Methods and compositions for weed control

专利摘要:
Provided are novel compositions for use in herbicide activity. Specifically, methods and compositions that modulate 5-enolpyruvylshikimate-3-phosphate synthase in plant species. The present invention also provides for combinations of compositions and methods that enhance weed control.
公开号:AU2012308818A1
申请号:U2012308818
申请日:2012-09-12
公开日:2014-03-27
发明作者:Daniel ADER；Zhaolong Li；Ronak Hasmukh Shah；Nengbing Tao；Dafu Wang；Heping Yang
申请人:Monsanto Technology LLC；
IPC主号:C12N15-82

专利说明:
WO 2013/039990 PCT/US2012/054789 METHODS AND COMPOSITIONS FOR WEED CONTROL This application claims benefit under 35USC § 119(e) of United States provisional application serial no. 61/534,057 filed 09/13/2011, herein incorporated by reference in it's entirety. The sequence listing that is contained in the file named "4021(58634)B seq listing.txt", which is 1,722,262 bytes (measured in operating system MS-Windows) and was created on 7 Sept 2012, is filed herewith and incorporated herein by reference. FIELD The methods and compositions generally relates to the field of weed management. More specifically, relates to 5-enolpyruvylshikimate-3-phosphate synthase genes in plants and compositions containing polynucleotide molecules for modulating and/or regulating their expression. Further provided are methods and compositions useful for weed control. BACKGROUND Weeds are plants that compete with cultivated plants in an agronomic environment and cost farmers billions of dollars annually in crop losses and the expense of efforts to keep weeds under control. Weeds also serve as hosts for crop diseases and insect pests. The losses caused by weeds in agricultural production environments include decreases in crop yield, reduced crop quality, increased irrigation costs, increased harvesting costs, reduced land value, injury to livestock, and crop damage from insects and diseases harbored by the weeds. The principal means by which weeds cause these effects are: 1) competing with crop plants for water, nutrients, sunlight and other essentials for growth and development, 2) production of toxic or irritant chemicals that cause human or animal health problem, 3) production of immense quantities of seed or vegetative reproductive parts or both that contaminate agricultural products and perpetuate the species in agricultural lands, and 4) production on agricultural and nonagricultural lands of vast amounts of vegetation that must be disposed of. Herbicide tolerant weeds are a problem with nearly all herbicides in use, there is a need to effectively manage these weeds. There are over 365 weed biotypes currently identified as being herbicide resistant to one 1 WO 2013/039990 PCT/US2012/054789 or more herbicides by the Herbicide Resistance Action Committee (HRAC), the North American Herbicide Resistance Action Committee (NAHRAC), and the Weed Science Society of America (WSSA). The EPSPS (5-enolpyruvylshikimate-3-phosphate synthase) enzyme catalyzes the conversion of shikimate-3-phosphate into 5-enolpyruvyl-shikimate-3-phosphate, an intermediate in the biochemical pathway for creating three essential aromatic amino acids (tyrosine, phenylalanine, and tryptophan). The EPSPS enzyme is the target for the herbicide N phosphonomethyl glycine also known as glyphosate. SUMMARY In one aspect, the invention provides a method of plant control comprising an external application to a plant or plant part a composition comprising a polynucleotide and a transfer agent, wherein the polynucleotide is essentially identical or essentially complementary to an EPSPS gene sequence or fragment thereof, or to the RNA transcript of said EPSPS gene sequence or fragment thereof, wherein said EPSPS gene sequence is selected from the group consisting of SEQ ID NO: 1-120 or a polynucleotide fragment thereof. As a result of such application, the plant growth or development or reproductive ability is reduced or the plant is made more sensitive to an EPSPS inhibitor herbicide relative to a plant not treated with said composition. In this manner, plants that have become resistant to the application of glyphosate containining herbicides are made more susceptible to the herbicidal effects of a glyphosate containing herbicide, thus potentiating the effect of the herbicide. The polynucleotide fragment is at least 18 contiguous nucleotides, at least 19 contiguous nucleotides, at least 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO: 1-120 and the transfer agent comprises an organosilicone composition or compound. The polynucleotide fragment can be sense or anti-sense ssDNA or ssRNA, dsRNA, or dsDNA, or dsDNA/RNA hybrids. The composition can include various components that include more than one polynucleotide fragments, an EPSPS inhibitor herbicide and/or other herbicides that enhance the plant control activity of the composition. In another aspect, polynucleotide molecules and methods for modulating EPSPS gene expression in a plant species are provided. The method reduces, represses or otherwise delays 2 WO 2013/039990 PCT/US2012/054789 expression of an EPSPS gene in a plant comprising an external application to such plant of a composition comprising a polynucleotide and a transfer agent, wherein the polynucleotide is essentially identical or essentially complementary to an EPSPS gene sequence or fragment thereof, or to the RNA transcript of the EPSPS gene sequence or fragment thereof, wherein the EPSPS gene sequence is selected from the group consisting of SEQ ID NO: 1-120 or a polynucleotide fragment thereof. The polynucleotide fragment is at least 18 contiguous nucleotides, at least 19 contiguous nucleotides, at least 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO: 1-120 and the transfer agent is an organosilicone compound. The polynucleotide fragment can be sense or anti-sense ssDNA or ssRNA, dsRNA, or dsDNA, or dsDNA/RNA hybrids. In a further aspect, the polynucleotide molecule composition may be combined with other herbicidal (co-herbicides) compounds to provide additional control of unwanted plants in a field of cultivated plants. In a further aspect, the polynucleotide molecule composition may be combined with any one or more additional agricultural chemicals, such as, insecticides, fungicides, nematocides, bactericides, acaricides, growth regulators, chemosterilants, semiochemicals, repellents, attractants, pheromones, feeding stimulants, biopesticides, microbial pesticides or other biologically active compounds to form a multi-component pesticide giving an even broader spectrum of agricultural protection. BRIEF DESCRIPTION OF THE FIGURES The following drawings form part of the present specification and are included to further demonstrate certain aspects of the function of the compositions and method. The function may be better understood by reference to one or more of these drawings in combination with the detailed description of specific embodiments presented herein. The function can be more fully understood from the following description of the figures: Figure 1. Regions of the Palmer amaranth EPSPS coding sequence that are sensitive to trigger molecules Figure 2. Transgenic glyphosate tolerant corn plants treated with trigger polynucleotides and glyphosate 3 WO 2013/039990 PCT/US2012/054789 Figure 3. Transgenic cotton plants treated with trigger polynucleotides and glyphosate DETAILED DESCRIPTION Provided are methods and compositions containing a polynucleotide that provide for regulation, repression or delay and/or modulation of EPSPS (5-enolpyruvylshikimate-3 phosphate synthase) gene expression and enhanced control of weedy plant species and importantly glyphosate resistant weed biotypes. Aspects of the method can be applied to manage various weedy plants in agronomic and other cultivated environments. The following definitions and methods are provided to guide those of ordinary skill in the art. Unless otherwise noted, terms are to be understood according to conventional usage by those of ordinary skill in the relevant art. Where a term is provided in the singular, the inventors also contemplate aspects described by the plural of that term. By "non-transcribable" polynucleotides is meant that the polynucleotides do not comprise a complete polymerase II transcription unit. As used herein "solution" refers to homogeneous mixtures and non-homogeneous mixtures such as suspensions, colloids, micelles, and emulsions. Weedy plants are plants that compete with cultivated plants, those of particular importance include, but are not limited to important invasive and noxious weeds and herbicide resistant biotypes in crop production, such as, Amaranthus species -A. albus, A. blitoides, A. hybridus, A. palmeri, A. powellii, A. retroflexus, A. spinosus, A. tuberculatus, and A. viridis; Ambrosia species - A. trifida, A. artemisifolia; Lolium species -L. multiflorum, L. rigidium, L perenne; Digitaria species -D. insularis; Euphorbia species -E. heterophylla; Kochia species K. scoparia; Sorghum species -S. halepense; Conyza species -C. bonariensis, C. canadensis, C. sumatrensis; Chloris species -C. truncate; Echinochola species - E. colona, E. crus-galli; Eleusine species -E. indica; Poa species -P. annua; Plantago species -P. lanceolata; Avena species - A. fatua; Chenopodium species - C. album; Setaria species - S. viridis, Abutilon theophrasti, Ipomoea species, Sesbania, species, Cassia species, Sida species, Brachiaria, species and Solanum species. 4 WO 2013/039990 PCT/US2012/054789 Additional weedy plant species found in cultivated areas include Alopecurus myosuroides, Avena sterilis, Avena sterilis ludoviciana, Brachiaria plantaginea, Bromus diandrus, Bromus rigidus, Cynosurus echinatus, Digitaria ciliaris, Digitaria ischaemum, Digitaria sanguinalis, Echinochloa oryzicola, Echinochloa phyllopogon, Eriochloa punctata, Hordeum glaucum, Hordeum leporinum, Ischaemum rugosum, Leptochloa chinensis, Lolium persicum, , Phalaris minor, Phalaris paradoxa, Rottboellia exalta, Setaria faberi, Setaria viridis var, robusta-alba schreiber, Setaria viridis var, robusta -purpurea, Snowdenia polystachea, Sorghum sudanese, Alisma plantago-aquatica, Amaranthus lividus, Amaranthus quitensis, Ammania auriculata, Ammania coccinea, Anthemis cotula, Apera spica-venti, Bacopa rotundifolia, Bidens pilosa, Bidens subalternans, Brassica tournefortii, Bromus tectorum, Camelina microcarpa, Chrysanthemum coronarium, Cuscuta campestris, Cyperus difformis, Damasonium minus, Descurainia sophia, Diplotaxis tenuifolia, Echium plantagineum, Elatine triandra var, pedicellata, Euphorbia heterophylla, Fallopia convolvulus, Fimbristylis miliacea, Galeopsis tetrahit, Galium spurium, Helianthus annuus, Iva xanthifolia, Ixophorus unisetus, Ipomoea indica, Ipomoea purpurea, Ipomoea sepiaria, Ipomoea aquatic, Ipomoea triloba, Lactuca serriola, Limnocharisflava, Limnophila erecta, Limnophila sessiliflora, Lindernia dubia, Lindernia dubia var, major, Lindernia micrantha, Lindernia procumbens, Mesembryanthemum crystallinum, Monochoria korsakowii, Monochoria vaginalis, Neslia paniculata, Papaver rhoeas, Parthenium hysterophorus, Pentzia suffruticosa, Phalaris minor, Raphanus raphanistrum, Raphanus sativus, Rapistrum rugosum, Rotala indica var, uliginosa, Sagittaria guyanensis, Sagittaria montevidensis, Sagittaria pygmaea, Salsola iberica, Scirpus juncoides var, ohwianus, Scirpus mucronatus, Setaria lutescens, Sida spinosa, Sinapis arvensis, Sisymbrium orientale, Sisymbrium thellungii, Solanum ptycanthum, Sonchus asper, Sonchus oleraceus, Sorghum bicolor, Stellaria media, Thlaspi arvense, Xanthium strumarium, Arctotheca calendula, Conyza sumatrensis, Crassocephalum crepidiodes, Cuphea carthagenenis, Epilobium adenocaulon, Erigeron philadelphicus, Landoltia punctata, Lepidium virginicum, Monochoria korsakowii, Solanum americanum, Solanum nigrum, Vulpia bromoides, Youngia japonica, Hydrilla verticillata, Carduus nutans, Carduus pycnocephalus, Centaurea solstitialis, Cirsium arvense, Commelina diffusa, Convolvulus arvensis, Daucus carota, Digitaria ischaemum, Echinochloa crus-pavonis, Fimbristylis miliacea, Galeopsis tetrahit, Galium spurium, Limnophila erecta, Matricaria perforate, Papaver rhoeas, Ranunculus acris, Soliva sessilis, 5 WO 2013/039990 PCT/US2012/054789 Sphenoclea zeylanica, Stellaria media, Nassella trichotoma, Stipa neesiana, Agrostis stolonifera, Polygonum aviculare, Alopecurus japonicus, Beckmannia syzigachne, Bromus tectorum, Chloris inflate, Echinochloa erecta, Portulaca oleracea, and Senecio vulgaris. It is believed that all plants contain a phytoene desaturase gene in their genome, the sequence of which can be isolated and polynucleotides made according to the methods of the present invention that are useful for regulation, suppressing or delaying the expression of the target EPSPS gene in the plants and the growth or development of the treated plants. A cultivated plant may also be considered a weedy plant when it occurs in unwanted environments. For example, corn plants growing in a soybean field. Transgenic crops with one or more herbicide tolerances may need specialized methods of management to control weeds and volunteer crop plants. The method enables the targeting of a transgene for herbicide tolerance to permit the treated plants to become sensitive to the herbicide. For example, an EPSPS DNA contained in a transgenic crop event can be a target for trigger molecules in order to render the transgenic crop sensitive to application of the corresponding glyphosate containing herbicide. Such transgenic events are known in the art and include but are not limited to DAS-44406-6, MON883302, MON87427, FG72, HCEM485, H7-1, ASR368, JIO, J163, DP-098140, GHB614, 356043, MON89788, MON88913, RT200, NK603, GTSB77, GA21, MON1445, and 40-3-2 and US patent publications: 20110126310, 20090137395, herein incorporated in their entirety by reference hereto. A "trigger" or "trigger polynucleotide" is a polynucleotide molecule that is homologous or complementary to a target gene polynucleotide. The trigger polynucleotide molecules modulate expression of the target gene when topically applied to a plant surface with a transfer agent, whereby a plant treated with said composition has its growth or development or reproductive ability regulated, suppressed or delayed or said plant is more sensitive to an EPSPS inhibitor herbicide as a result of said polynucleotide containing composition relative to a plant not treated with a composition containing the trigger molecule. Trigger polynucleotides disclosed herein are generally described in relation to the target gene sequence and maybe used in the sense (homologous) or antisense (complementary) orientation as single stranded molecules or comprise both strands as double stranded molecules or nucleotide variants and modified nucleotides thereof depending on the various regions of a gene being targeted. 6 WO 2013/039990 PCT/US2012/054789 It is contemplated that the composition may contain multiple polynucleotides and herbicides that include but are not limited to EPSPS gene trigger polynucleotides and an EPSPS inhibitor herbicide and one or more additional herbicide target gene trigger polynucleotides and the related herbicides and one or more additional essential gene trigger polynucleotides. Essential genes are genes in a plant that provide key enzymes or other proteins, for example, a biosynthetic enzyme, metabolizing enzyme, receptor, signal transduction protein, structural gene product, transcription factor, or transport protein; or regulating RNAs, such as, microRNAs, that are essential to the growth or survival of the organism or cell or involved in the normal growth and development of the plant (Meinke, et al., Trends Plant Sci. 2008:13(9):483-9 1). The suppression of an essential gene enhances the effect of a herbicide that affects the function of a gene product different than the suppressed essential gene. The compositions can include various trigger polynucleotides that modulate the expression of an essential gene other than an EPSPS gene. Herbicides for which transgenes for plant tolerance have been demonstrated and the method can be applied, include but are not limited to: auxin-like herbicides, glyphosate, glufosinate, sulfonylureas, imidazolinones, bromoxynil, delapon, dicamba, cyclohezanedione, protoporphyrionogen oxidase inhibitors, 4-hydroxyphenyl-pyruvate-dioxygenase inhibitors herbicides. For example, transgenes and their polynucleotide molecules that encode proteins involved in herbicide tolerance are known in the art, and include, but are not limited to an 5 enolpyruvylshikimate-3-phosphate synthase (EPSPS), for example, as more fully described in U.S. Pat. Nos. 7,807,791 (SEQ ID NO:5); 6,248,876 Bi; 5,627,061; 5,804,425; 5,633,435; 5,145,783; 4,971,908; 5,312,910; 5,188,642; 4,940,835; 5,866,775; 6,225,114 Bi; 6,130,366; 5,310,667; 4,535,060; 4,769,061; 5,633,448; 5,510,471; U.S. Pat. No. Re. 36,449; U.S. Pat. Nos. RE 37,287 E; and 5,491,288; tolerance to sulfonylurea and/or imidazolinone, for example, as described more fully in U.S. Pat. Nos. 5,605,011; 5,013,659; 5,141,870; 5,767,361; 5,731,180; 5,304,732; 4,761,373; 5,331,107; 5,928,937; and 5,378,824; and international publication WO 96/33270; tolerance to hydroxyphenylpyruvatedioxygenases inhibiting herbicides in plants are described in U.S. Pat. Nos. 6,245,968 B1; 6,268,549; and 6,069,115; and US7,312,379 SEQ ID NO:3; US7,935,869; US7,304,209, SEQ ID NO:1, 3,5 and 15; aryloxyalkanoate dioxygenase polynucleotides, which confer tolerance to 2,4-D and other phenoxy auxin herbicides as well as to aryloxyphenoxypropionate herbicides as described, for example, in W02005/107437; 7 WO 2013/039990 PCT/US2012/054789 US7,838,733 SEQ ID NO:5;) and dicamba-tolerance polynucleotides as described, for example, in Herman et al. (2005) J. Biol. Chem. 280: 24759-24767. Other examples of herbicide-tolerance traits include those conferred by polynucleotides encoding an exogenous phosphinothricin acetyltransferase, as described in U.S. Pat. Nos. 5,969,213; 5,489,520; 5,550,318; 5,874,265; 5,919,675; 5,561,236; 5,648,477; 5,646,024; 6,177,616; and 5,879,903. Plants containing an exogenous phosphinothricin acetyltransferase can exhibit improved tolerance to glufosinate herbicides, which inhibit the enzyme glutamine synthase. Additionally, herbicide-tolerance polynucleotides include those conferred by polynucleotides conferring altered protoporphyrinogen oxidase (protox) activity, as described in U.S. Pat. Nos. 6,288,306 BI; 6,282,837 B1; and 5,767,373; and WO 0 1/12825. Plants containing such polynucleotides can exhibit improved tolerance to any of a variety of herbicides which target the protox enzyme (also referred to as protox inhibitors). Polynucleotides encoding a glyphosate oxidoreductase and a glyphosate-N-acetyl transferase (GOX described in U.S. Patent 5,463,175 and GAT described in U.S. Patent publication 20030083480, dicamba monooxygenase U.S. Patent 7,022,896 and 7,884,262, all of which are incorporated herein by reference); a polynucleotide molecule encoding bromoxynil nitrilase (Bxn described in U.S. Patent No. 4,810,648 for Bromoxynil tolerance, which is incorporated herein by reference); a polynucleotide molecule encoding phytoene desaturase (crtI) described in Misawa et al, (1993) Plant J. 4:833-840 and Misawa et al, (1994) Plant J. 6:481-489 for norflurazon tolerance; a polynucleotide molecule encoding acetohydroxyacid synthase (AHAS, aka ALS) described in Sathasiivan et al. (1990) Nucl. Acids Res. 18:2188-2193 for tolerance to sulfonylurea herbicides; and the bar gene described in DeBlock, et al. (1987) EMBO J. 6:2513-2519 for glufosinate and bialaphos tolerance. The transgenic coding regions and regulatory elements of the herbicide tolerance genes are targets in which polynucleotide triggers and herbicides can be included in the composition and combinations thereof to provide for enhanced methods of weed control. "Glyphosate" (N-phosphonomethylglycine) herbicide inhibits the shikimic acid pathway which leads to the biosynthesis of aromatic compounds including amino acids, plant hormones and vitamins. Specifically, glyphosate curbs the conversion of phosphoenolpyruvic acid (PEP) and 3-phosphoshikimic acid to 5-enolpyruvyl-3-phosphoshikimic acid by inhibiting the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (hereinafter referred to as EPSP synthase or EPSPS). The term "glyphosate" should be considered to include any herbicidally effective form 8 WO 2013/039990 PCT/US2012/054789 of N-phosphonomethylglycine (including any salt thereof) and other forms which result in the production of the glyphosate anion in planta. Glyphosate is an example of an EPSPS inhibitor herbicide. Herbicides are molecules that affect plant growth or development or reproductive ability. Glyphosate is commercially available in numerous formulations. Examples of these formulations of glyphosate include, without limitation, those sold by Monsanto Company (St Louis, MO) as ROUNDUP.RTM., ROUNDUP.RTM. ULTRA, ROUNDUP.RTM. ULTRAMAX, ROUNDUP.RTM. CT, ROUNDUP.RTM. EXTRA, ROUNDUP.RTM. BIACTIVE, ROUNDUP.RTM. BIOFORCE, RODEO.RTM., POLARIS.RTM., SPARK.RTM. and ACCORD.RTM. herbicides, all of which contain glyphosate as its isopropylammonium salt, ROUNDUP.RTM. WEATHERMAX containing glyphosate as its potassium salt; ROUNDUP.RTM. DRY and RIVAL.RTM. herbicides, which contain glyphosate as its ammonium salt; ROUNDUP.RTM. GEOFORCE, which contains glyphosate as its sodium salt; and TOUCHDOWN.RTM. herbicide (Syngenta, Greensboro, NC), which contains glyphosate as its trimethylsulfonium salt. Various other salts of glyphosate are available for example, dimethylamine salt, isopropylamine salt, trimesium salt, potassium salt, monoammonium salt, and diammonium salt. Commerical formulations and application rates thereof are often defined in terms of acid equivalent pounds pe acre (a.e. Lb/ac). Numerous herbicides with similar or different modes of action (herein referred to as co herbicides) are available that can be added to the composition that provide multi-species weed control or alternative modes of action for difficult to control weed species, for example, members of the herbicide families that include but are not limited to amide herbicides, aromatic acid herbicides, arsenical herbicides, benzothiazole herbicides, benzoylcyclohexanedione herbicides, benzofuranyl alkylsulfonate herbicides, carbamate herbicides, cyclohexene oxime herbicides, cyclopropylisoxazole herbicides, dicarboximide herbicides, dinitroaniline herbicides, dinitrophenol herbicides, diphenyl ether herbicides, dithiocarbamate herbicides, halogenated aliphatic herbicides, imidazolinone herbicides, inorganic herbicides, nitrile herbicides, organophosphorus herbicides, oxadiazolone herbicides, oxazole herbicides, phenoxy herbicides, phenylenediamine herbicides, pyrazole herbicides, pyridazine herbicides, pyridazinone herbicides, pyridine herbicides, pyrimidinediamine herbicides, pyrimidinyloxybenzylamine herbicides, quaternary ammonium herbicides, thiocarbamate herbicides, thiocarbonate 9 WO 2013/039990 PCT/US2012/054789 herbicides, thiourea herbicides, triazine herbicides, triazinone herbicides, triazole herbicides, triazolone herbicides, triazolopyrimidine herbicides, uracil herbicides, and urea herbicides. In particular, the rates of use of the added herbicides can be reduced in compositions comprising the polynucleotides. Use rate reductions of the additional added herbicides can be 10-25 percent, 26-50 percent, 51-75 percent or more can be achieved that enhance the activity of the polynucleotides and herbicide composition and is contemplated. Representative herbicides of the families include but are not limited to acetochlor, acifluorfen, acifluorfen-sodium, aclonifen, acrolein, alachlor, alloxydim, allyl alcohol, ametryn, amicarbazone, amidosulfuron, aminopyralid, amitrole, ammonium sulfamate, anilofos, asulam, atraton, atrazine, azimsulfuron, BCPC, beflubutamid, benazolin, benfluralin, benfuresate, bensulfuron, bensulfuron-methyl, bensulide, bentazone, benzfendizone, benzobicyclon, benzofenap, bifenox, bilanafos, bispyribac, bispyribac-sodium, borax, bromacil, bromobutide, bromoxynil, butachlor, butafenacil, butamifos, butralin, butroxydim, butylate, cacodylic acid, calcium chlorate, cafenstrole, carbetamide, carfentrazone, carfentrazone-ethyl, CDEA, CEPC, chlorflurenol, chlorflurenol-methyl, chloridazon, chlorimuron, chlorimuron ethyl, chloroacetic acid, chlorotoluron, chlorpropham, chlorsulfuron, chlorthal, chlorthal dimethyl, cinidon-ethyl, cinmethylin, cinosulfuron, cisanilide, clethodim, clodinafop, clodinafop-propargyl, clomazone, clomeprop, clopyralid, cloransulam, cloransulam-methyl, CMA, 4-CPB, CPMF, 4-CPP, CPPC, cresol, cumyluron, cyanamide, cyanazine, cycloate, cyclosulfamuron, cycloxydim, cyhalofop, cyhalofop-butyl, 2,4-D, 3,4-DA, daimuron, dalapon, dazomet, 2,4-DB, 3,4-DB, 2,4-DEB, desmedipham, dicamba, dichlobenil, ortho dichlorobenzene, para-dichlorobenzene, dichlorprop, dichlorprop-P, diclofop, diclofop methyl, diclosulam, difenzoquat, difenzoquat metilsulfate, diflufenican, diflufenzopyr, dimefuron, dimepiperate, dimethachlor, dimethametryn, dimethenamid, dimethenamid-P, dimethipin, dimethylarsinic acid, dinitramine, dinoterb, diphenamid, diquat, diquat dibromide, dithiopyr, diuron, DNOC, 3,4-DP, DSMA, EBEP, endothal, EPTC, esprocarb, ethalfluralin, ethametsulfuron, ethametsulfuron-methyl, ethofumesate, ethoxyfen, ethoxysulfuron, etobenzanid, fenoxaprop-P, fenoxaprop-P-ethyl, fentrazamide, ferrous sulfate, flamprop-M, flazasulfuron, florasulam, fluazifop, fluazifop-butyl, fluazifop-P, fluazifop-P-butyl, flucarbazone, flucarbazone- sodium, flucetosulfuron, fluchloralin, flufenacet, flufenpyr, flufenpyr-ethyl, flumetsulam, flumiclorac, flumiclorac-pentyl, 10 WO 2013/039990 PCT/US2012/054789 flumioxazin, fluometuron, fluoroglycofen, fluoroglycofen-ethyl, flupropanate, flupyrsulfuron, flupyrsulfuron-methyl-sodium, flurenol, fluridone, fluorochloridone, fluoroxypyr, flurtamone, fluthiacet, fluthiacet-methyl, fomesafen, foramsulfuron, fosamine, glufosinate, glufosinate ammonium, glyphosate, halosulfuron, halosulfuron-methyl, haloxyfop, haloxyfop-P, HC 252, hexazinone, imazamethabenz, imazamethabenz-methyl, imazamox, imazapic, imazapyr, imazaquin, imazethapyr, imazosulfuron, indanofan, iodomethane, iodosulfuron, iodosulfuron-methyl- sodium, ioxynil, isoproturon, isouron, isoxaben, isoxachlortole, isoxaflutole, karbutilate, lactofen, lenacil, linuron, MAA, MAMA, MCPA, MCPA thioethyl, MCPB, mecoprop, mecoprop-P, mefenacet, mefluidide, mesosulfuron, mesosulfuron-methyl, mesotrione, metam, metamifop, metamitron, metazachlor, methabenzthiazuron, methylarsonic acid, methyldymron, methyl isothiocyanate, metobenzuron, metolachlor, S-metolachlor, metosulam, metoxuron, metribuzin, metsulfuron, metsulfuron-methyl, MK-66, molinate, monolinuron, MSMA, naproanilide, napropamide, naptalam, neburon, nicosulfuron, nonanoic acid, norflurazon, oleic acid (fatty acids), orbencarb, orthosulfamuron, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone, oxyfluorfen, paraquat, paraquat dichloride, pebulate, pendimethalin, penoxsulam, pentachlorophenol, pentanochlor, pentoxazone, pethoxamid, petrolium oils, phenmedipham, phenmedipham-ethyl, picloram, picolinafen, pinoxaden, piperophos, potassium arsenite, potassium azide, pretilachlor, primisulfuron, primisulfuron-methyl, prodiamine, profluazol, profoxydim, prometon, prometryn, propachlor, propanil, propaquizafop, propazine, propham, propisochlor, propoxycarbazone, propoxycarbazone- sodium, propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraflufen, pyraflufen-ethyl, pyrazolynate, pyrazosulfuron, pyrazosulfuron-ethyl, pyrazoxyfen, pyribenzoxim, pyributicarb, pyridafol, pyridate, pyriftalid, pyriminobac, pyriminobac-methyl, pyrimisulfan, pyrithiobac, pyrithiobac- sodium, quinclorac, quinmerac, quinoclamine, quizalofop, quizalofop-P, rimsulfuron, sethoxydim, siduron, simazine, simetryn, SMA, sodium arsenite, sodium azide, sodium chlorate, sulcotrione, sulfentrazone, sulfometuron, sulfometuron-methyl, sulfosate, sulfosulfuron, sulfuric acid, tar oils, 2,3,6-TBA, TCA, TCA-sodium, tebuthiuron, tepraloxydim, terbacil, terbumeton, terbuthylazine, terbutryn, thenylchlor, thiazopyr, thifensulfuron, thifensulfuron-methyl, thiobencarb, tiocarbazil, topramezone, tralkoxydim, tri-allate, triasulfuron, triaziflam, tribenuron, tribenuron-methyl, tricamba, triclopyr, 11 WO 2013/039990 PCT/US2012/054789 trietazine, trifloxysulfuron, trifloxysulfuron-sodium, trifluralin, triflusulfuron, triflusulfuron methyl, trihydroxytriazine, tritosulfuron, [3-[2-chloro-4-fluoro-5-(-methyl-6-trifluoromethyl 2,4-dioxo-,2,3,4-t- etrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy] acetic acid ethyl ester (CAS RN 353292-3-6), 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo)-H-,2,4-triazol--ylcarbonyl sulfamoyl]-5-methylthiophene-3-carboxylic acid (BAY636), BAY747 (CAS RN 33504-84-2), topramezone (CAS RN 2063-68-8), 4-hydroxy-3-[[2-[(2-methoxyethoxy)methyl]-6-(trifluoro methyl)-3-pyridi- nyl]carbonyl] -bicyclo[3.2.] oct-3-en-2-one (CAS RN 35200-68-5), and 4 hydroxy-3- [[2- (3-methoxypropyl)-6- (difluoromethyl)-3 -pyridinyl] carbon- yl]-bicyclo[3.2.]oct-3 en-2-one. Additionally, including herbicidal compounds of unspecified modes of action as described in CN101279950A, CN101279951A, DE10000600A1, DE10116399A1, DE102004054666A1, DE102005014638A1, DE102005014906A1, DE102007012168A1, DE102010042866A1, DE10204951A1, DE10234875A1, DE10234876A1, DE10256353A1, DE10256354A1, DE10256367A1, EP1157991A2, EP1238586A1, EP2147919A1, EP2160098A2, JP03968012B2, JP2001253874A, JP2002080454A, JP2002138075A, JP2002145707A, JP2002220389A, JP2003064059A, JP2003096059A, JP2004051628A, JP2004107228A, JP2005008583A, JP2005239675A, JP2005314407A, JP2006232824A, JP2006282552A, JP2007153847A, JP2007161701A, JP2007182404A, JP2008074840A, JP2008074841A, JP2008133207A, JP2008133218A, JP2008169121A, JP2009067739A, JP2009114128A, JP2009126792A, JP2009137851A, US20060111241A1, US20090036311A1, US20090054240A1, US20090215628A1, US20100099561A1, US20100152443A1, US20110105329A1, US20110201501A1, W02001055066A2, W02001056975A1, W02001056979A1, W02001090071A2, W02001090080A1, W02002002540A1 , W02002028182A1, W02002040473A1, W02002044173A2, W02003000679A2, W02003006422A1 , W02003013247A1, W02003016308A1, W02003020704A1, W02003022051A1, W02003022831A1, W02003022843A1, W02003029243A2, W02003037085A1, W02003037878A1, W02003045878A2, W02003050087A2, W02003051823A1, W02003051824A1, W02003051846A2, W02003076409A1, W02003087067A1, W02003090539A1, W02003091217A1, W02003093269A2, W02003104206A2, W02004002947A1, W02004002981A2, W02004011429A1, W02004029060A1, W02004035545A2, W02004035563A1, W02004035564A1, W02004037787A1, W02004067518A1, W02004067527A1, W02004077950A1, 12 WO 2013/039990 PCT/US2012/054789 W02005000824A1, W02005007627A1, W02005040152A1, W02005047233A1, W02005047281A1, W02005061443A2, W02005061464A1, W02005068434A1, W02005070889A1, W02005089551A1, W02005095335A1, W02006006569A1, W02006024820A1, W02006029828A1, W02006029829A1, W02006037945A1, W02006050803A1, W02006090792A1, W02006123088A2, W02006125687A1, W02006125688A1, W02007003294A1, W02007026834A1, W02007071900A1, W02007077201A1, W02007077247A1, W02007096576A1, W02007119434A1, W02007134984A1, W02008009908A1, W02008029084A1, W02008059948A1, W02008071918A1, W02008074991A1, W02008084073A1, W02008100426A2, W02008102908A1, W02008152072A2, W02008152073A2, W02009000757A1, W02009005297A2, W02009035150A2, W02009063180A1, W02009068170A2, W02009068171A2, W02009086041A1, W02009090401A2, W02009090402A2, W02009115788A1, W02009116558A1, W02009152995A1, W02009158258A1, W02010012649A1, W02010012649A1, W02010026989A1, W02010034153A1, W02010049270A1, W02010049369A1, W02010049405A1, W02010049414A1, W02010063422A1, W02010069802A1, W02010078906A2, W02010078912A1, W02010104217A1, W02010108611A1, W02010112826A3, W02010116122A3, W02010119906A1, W02010130970A1, W02011003776A2, W02011035874A1, W0201106545 1A1, all of which are incorporated herein by reference. Auxin-like herbicides include benzoic acid herbicide, phenoxy carboxylic acid herbicide, pyridine carboxylic acid herbicide, quinoline carboxylic acid herbicide, pyrimidine carboxylic acid herbicide, and benazolin-ethyl herbicide. The benzoic acid herbicide group (dicamba (3,6-dichloro-o-anisic acid), chloramben (3 amino-2,5-dichlorobenzoic acid), and TBA (2,3,6-trichlorobenzoic acid)) are effective herbicides for both pre-emergence and post-emergence weed management. Dicamba is one of the many auxin-like herbicides that is a low-cost, environmentally friendly herbicide that has been used as a pre-emergence and post-emergence herbicide to effectively control annual and perennial broadleaf weeds and several grassy weeds in corn, sorghum, small grains, pasture, hay, rangeland, sugarcane, asparagus, turf, and grass seed crops (Crop Protection Chemicals Reference, pp. 1803-1821, Chemical & Pharmaceutical Press, Inc., New York, NY, 11th ed., 1995). Dicamba refers to 3,6-dichloro-o-anisic acid or 3,6-dichloro-2-methoxy benzoic acid and 13 WO 2013/039990 PCT/US2012/054789 its acids and salts. Its salts include isopropylamine, diglycoamine, dimethylamine, potassium and sodium. Dicamba includes for example, commercial formulations without limitation, Banvel T M (as DMA salt, BASF, Research Triangle Park, NC), Clarity@ (DGA salt, BASF), VEL-58-CS-1 1TM (BASF) and Vanquish T M (DGA salt, BASF). Dicamba is a useful herbicide as a tank mix, concomitantly, or pre or post treatment with the compositions. An auxin-like herbicide also includes a phenoxy carboxylic acid compound, a pyridine carboxylic acid compound, a quinoline carboxylic acid compound, and a benazolin-ethyl compound. Examples of a phenoxy carboxylic acid compound include, but are not limited to 2,4-dichlorophenoxyacetic acid, (4-chloro-2-methylphenoxy) acetic acid, diclorprop (2,4-DP), mecoprop (MCPP), and clomeprop. Examples of pyridine herbicides include, but are not limited to clopryalid, picloram, fluroxypyr, aminocyclopyrachlor and triclopyr. These auxin-like herbicides are useful in a tank mix, concomitantly, or pre or post treatment with the compositions. Auxin-like herbicides include commercially available formulations, for example,including but not limited to 2,4-D, 2,4-DB (Butyrac@ 200, Bakker), MCPA (Rhonox@, Rhomene), mecoprop, dichlorprop, 2,4,5-T, triclopyr (Garlon@, Dow AgroSciences, Indianapolis, IN), chloramben, dicamba (Banvel@, Clarity@, Oracle@, Sterling®), 2,3,6-TBA, tricamba, clopyralid (Stinger@, Dow AgroSciences), picloram (Tordon®, Dow AgroSciences), quinmerac, quinclorac, benazolin, fenac, IAA, NAA, orthonil and fluroxypyr (Vista@, Starane@, Dow AgroSciences), aminopyralid (Milestone@, Dow AgroSciences) and aminocyclopyrachlor (Dupont, Wilmington, DE). The trigger polynucleotide and oligonucleotide molecule compositions are useful in compositions, such as liquids that comprise the polynucleotide molecules at low concentrations, alone or in combination with other components, for example one or more herbicide molecules, either in the same solution or in separately applied liquids that also provide a transfer agent. While there is no upper limit on the concentrations and dosages of polynucleotide molecules that can useful in the methods, lower effective concentrations and dosages will generally be sought for efficiency. The concentrations can be adjusted in consideration of the volume of spray or treatment applied to plant leaves or other plant part surfaces, such as flower petals, stems, tubers, fruit, anthers, pollen, or seed. In one embodiment, a useful treatment for herbaceous plants using 25-mer oligonucleotide molecules is about 1 nanomole (nmol) of oligonucleotide molecules per plant, for example, from about 0.05 to 1 nmol per plant. Other embodiments for herbaceous 14 WO 2013/039990 PCT/US2012/054789 plants include useful ranges of about 0.05 to about 100 nmol, or about 0.1 to about 20 nmol, or about 1 nmol to about 10 nmol of polynucleotides per plant. Very large plants, trees, or vines may require correspondingly larger amounts of polynucleotides. When using long dsRNA molecules that can be processed into multiple oligonucleotides, lower concentrations can be used. To illustrate embodiments, the factor 1X, when applied to oligonucleotide molecules is arbitrarily used to denote a treatment of 0.8 nmol of polynucleotide molecule per plant; lOX, 8 nmol of polynucleotide molecule per plant; and 10OX, 80 nmol of polynucleotide molecule per plant. The polynucleotide compositions are useful in compositions, such as liquids that comprise polynucleotide molecules, alone or in combination with other components either in the same liquid or in separately applied liquids that provide a transfer agent. As used herein, a transfer agent is an agent that, when combined with a polynucleotide in a composition that is topically applied to a target plant surface, enables the polynucleotide to enter a plant cell. In certain embodiments, a transfer agent is an agent that conditions the surface of plant tissue, e. g., leaves, stems, roots, flowers, or fruits, to permeation by the polynucleotide molecules into plant cells. The transfer of polynucleotides into plant cells can be facilitated by the prior or contemporaneous application of a polynucleotide-transferring agent to the plant tissue. In some embodiments the transferring agent is applied subsequent to the application of the polynucleotide composition. The polynucleotide transfer agent enables a pathway for polynucleotides through cuticle wax barriers, stomata and/or cell wall or membrane barriers into plant cells. Suitable transfer agents to facilitate transfer of the polynucleotide into a plant cell include agents that increase permeability of the exterior of the plant or that increase permeability of plant cells to oligonucleotides or polynucleotides. Such agents to facilitate transfer of the composition into a plant cell include a chemical agent, or a physical agent, or combinations thereof. Chemical agents for conditioning or transfer include (a) surfactants, (b) an organic solvent or an aqueous solution or aqueous mixtures of organic solvents, (c) oxidizing agents, (d) acids, (e) bases, (f) oils, (g) enzymes, or combinations thereof. Embodiments of the method can optionally include an incubation step, a neutralization step (e.g., to neutralize an acid, base, or oxidizing agent, or to inactivate an enzyme), a rinsing step, or combinations thereof. Embodiments of agents or treatments for conditioning of a plant to permeation by polynucleotides include emulsions, reverse emulsions, liposomes, and other micellar-like compositions. Embodiments of agents or 15 WO 2013/039990 PCT/US2012/054789 treatments for conditioning of a plant to permeation by polynucleotides include counter-ions or other molecules that are known to associate with nucleic acid molecules, e. g., inorganic ammonium ions, alkyl ammonium ions, lithium ions, polyamines such as spermine, spermidine, or putrescine, and other cations. Organic solvents useful in conditioning a plant to permeation by polynucleotides include DMSO, DMF, pyridine, N-pyrrolidine, hexamethylphosphoramide, acetonitrile, dioxane, polypropylene glycol, other solvents miscible with water or that will dissolve phosphonucleotides in non-aqueous systems (such as is used in synthetic reactions). Naturally derived or synthetic oils with or without surfactants or emulsifiers can be used, e. g., plant-sourced oils, crop oils (such as those listed in the 9h Compendium of Herbicide Adjuvants, publicly available on the worldwide web (internet) at herbicide.adjuvants.com can be used, e. g., paraffinic oils, polyol fatty acid esters, or oils with short-chain molecules modified with amides or polyamines such as polyethyleneimine or N-pyrrolidine. Transfer agents include, but are not limited to, organosilicone preparations. An agronomic field in need of plant control is treated by application of an agricultural chemical composition directly to the surface of the growing plants, such as by a spray. For example, the method is applied to control weeds in a field of crop plants by spraying the field with the composition. The composition can be provided as a tank mix with one or more herbicidal chemical and additional pesticidal chemicals to control pests and diseases of the crop plants in need of pest and disease control, a sequential treatment of components (generally the polynucleotide containing composition followed by the herbicide), or a simultaneous treatment or mixing of one or more of the components of the composition from separate containers. Treatment of the field can occur as often as needed to provide weed control and the components of the composition can be adjusted to target specific weed species or weed families through utilization of specific polynucleotides or polynucleotide compositions capable of selectively targeting the specific species or plant family to be controlled. The composition can be applied at effective use rates according to the time of application to the field, for example, preplant, at planting, post planting, post harvest. Glyphosate can be applied to a field at rates of 11-44 ounces/acre upto 7.2875 pounds/acre. The polynucleotides of the composition can be applied at rates of 1 to 30 grams per acre depending on the number of trigger molecules needed for the scope of weeds in the field. 16 WO 2013/039990 PCT/US2012/054789 Crop plants in which weed control may be needed include but are not limited to corn, soybean, cotton, canola, sugar beet, alfalfa, sugarcane, rice, and wheat; vegetable plants including, but not limited to, tomato, sweet pepper, hot pepper, melon, watermelon, cucumber, eggplant, cauliflower, broccoli, lettuce, spinach, onion, peas, carrots, sweet corn, Chinese cabbage, leek, fennel, pumpkin, squash or gourd, radish, Brussels sprouts, tomatillo, garden beans, dry beans, or okra; culinary plants including, but not limited to, basil, parsley, coffee, or tea; or fruit plants including but not limited to apple, pear, cherry, peach, plum, apricot, banana, plantain, table grape, wine grape, citrus, avocado, mango, or berry; a tree grown for ornamental or commercial use, including, but not limited to, a fruit or nut tree; ornamental plant (e. g., an ornamental flowering plant or shrub or turf grass). The methods and compositions provided herein can also be applied to plants produced by a cutting, cloning, or grafting process (i.e., a plant not grown from a seed) including fruit trees and plants that include, but are not limited to, avocados, tomatoes, eggplant, cucumber, melons, watermelons, and grapes as well as various ornamental plants. Pesticidal Mixtures The polynucleotide compositions may also be used as mixtures with various agricultural chemicals and/or insecticides, miticides and fungicides, pesticidal and biopesticidal agents. Examples include but are not limited to azinphos-methyl, acephate, isoxathion, isofenphos, ethion, etrimfos, oxydemeton-methyl, oxydeprofos, quinalphos, chlorpyrifos, chlorpyrifos methyl, chlorfenvinphos, cyanophos, dioxabenzofos, dichlorvos, disulfoton, dimethylvinphos, dimethoate, sulprofos, diazinon, thiometon, tetrachlorvinphos, temephos, tebupirimfos, terbufos, naled, vamidothion, pyraclofos, pyridafenthion, pirimiphos-methyl, fenitrothion, fenthion, phenthoate, flupyrazophos, prothiofos, propaphos, profenofos, phoxime, phosalone, phosmet, formothion, phorate, malathion, mecarbam, mesulfenfos, methamidophos, methidathion, parathion, methyl parathion, monocrotophos, trichlorphon, EPN, isazophos, isamidofos, cadusafos, diamidaphos, dichlofenthion, thionazin, fenamiphos, fosthiazate, fosthietan, phosphocarb, DSP, ethoprophos, alanycarb, aldicarb, isoprocarb, ethiofencarb, carbaryl, carbosulfan, xylylcarb, thiodicarb, pirimicarb, fenobucarb, furathiocarb, propoxur, bendiocarb, benfuracarb, methomyl, metolcarb, XMC, carbofuran, aldoxycarb, oxamyl, acrinathrin, allethrin, esfenvalerate, empenthrin, cycloprothrin, cyhalothrin, gamma-cyhalothrin, lambda-cyhalothrin, 17 WO 2013/039990 PCT/US2012/054789 cyfluthrin, beta-cyfluthrin, cypermethrin, alpha-cypermethrin, zeta-cypermethrin, silafluofen, tetramethrin, tefluthrin, deltamethrin, tralomethrin, bifenthrin, phenothrin, fenvalerate, fenpropathrin, furamethrin, prallethrin, flucythrinate, fluvalinate, flubrocythrinate, permethrin, resmethrin, ethofenprox, cartap, thiocyclam, bensultap, acetamiprid, imidacloprid, clothianidin, dinotefuran, thiacloprid, thiamethoxam, nitenpyram, chlorfluazuron, diflubenzuron, teflubenzuron, triflumuron, novaluron, noviflumuron, bistrifluoron, fluazuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, chromafenozide, tebufenozide, halofenozide, methoxyfenozide, diofenolan, cyromazine, pyriproxyfen, buprofezin, methoprene, hydroprene, kinoprene, triazamate, endosulfan, chlorfenson, chlorobenzilate, dicofol, bromopropylate, acetoprole, fipronil, ethiprole, pyrethrin, rotenone, nicotine sulphate, BT (Bacillus Thuringiensis) agent, spinosad, abamectin, acequinocyl, amidoflumet, amitraz, etoxazole, chinomethionat, clofentezine, fenbutatin oxide, dienochlor, cyhexatin, spirodiclofen, spiromesifen, tetradifon, tebufenpyrad, binapacryl, bifenazate, pyridaben, pyrimidifen, fenazaquin, fenothiocarb, fenpyroximate, fluacrypyrim, fluazinam, flufenzin, hexythiazox, propargite, benzomate, polynactin complex, milbemectin, lufenuron, mecarbam, methiocarb, mevinphos, halfenprox, azadirachtin, diafenthiuron, indoxacarb, emamectin benzoate, potassium oleate, sodium oleate, chlorfenapyr, tolfenpyrad, pymetrozine, fenoxycarb, hydramethylnon, hydroxy propyl starch, pyridalyl, flufenerim, flubendiamide, flonicamid, metaflumizole, lepimectin, TPIC, albendazole, oxibendazole, oxfendazole, trichlamide, fensulfothion, fenbendazole, levamisole hydrochloride, morantel tartrate, dazomet, metam-sodium, triadimefon, hexaconazole, propiconazole, ipconazole, prochloraz, triflumizole, tebuconazole, epoxiconazole, difenoconazole, flusilazole, triadimenol, cyproconazole, metconazole, fluquinconazole, bitertanol, tetraconazole, triticonazole, flutriafol, penconazole, diniconazole, fenbuconazole, bromuconazole, imibenconazole, simeconazole, myclobutanil, hymexazole, imazalil, furametpyr, thifluzamide, etridiazole, oxpoconazole, oxpoconazole fumarate, pefurazoate, prothioconazole, pyrifenox, fenarimol, nuarimol, bupirimate, mepanipyrim, cyprodinil, pyrimethanil, metalaxyl, mefenoxam, oxadixyl, benalaxyl, thiophanate, thiophanate-methyl, benomyl, carbendazim, fuberidazole, thiabendazole, manzeb, propineb, zineb, metiram, maneb, ziram, thiuram, chlorothalonil, ethaboxam, oxycarboxin, carboxin, flutolanil, silthiofam, mepronil, dimethomorph, fenpropidin, fenpropimorph, spiroxamine, tridemorph, dodemorph, flumorph, azoxystrobin, kresoxim-methyl, metominostrobin, orysastrobin, fluoxastrobin, trifloxystrobin, dimoxystrobin, pyraclostrobin, 18 WO 2013/039990 PCT/US2012/054789 picoxystrobin, iprodione, procymidone, vinclozolin, chlozolinate, flusulfamide, dazomet, methyl isothiocyanate, chloropicrin, methasulfocarb, hydroxyisoxazole, potassium hydroxyisoxazole, echlomezol, D-D, carbam, basic copper chloride, basic copper sulfate, copper nonylphenolsulfonate, oxine copper, DBEDC, anhydrous copper sulfate, copper sulfate pentahydrate, cupric hydroxide, inorganic sulfur, wettable sulfur, lime sulfur, zinc sulfate, fentin, sodium hydrogen carbonate, potassium hydrogen carbonate, sodium hypochlorite, silver, edifenphos, tolclofos-methyl, fosetyl, iprobenfos, dinocap, pyrazophos, carpropamid, fthalide, tricyclazole, pyroquilon, diclocymet, fenoxanil, kasugamycin, validamycin, polyoxins, blasticiden S, oxytetracycline, mildiomycin, streptomycin, rape seed oil, machine oil, benthiavalicarbisopropyl, iprovalicarb, propamocarb, diethofencarb, fluoroimide, fludioxanil, fenpiclonil, quinoxyfen, oxolinic acid, chlorothalonil, captan, folpet, probenazole, acibenzolar-S methyl, tiadinil, cyflufenamid, fenhexamid, diflumetorim, metrafenone, picobenzamide, proquinazid, famoxadone, cyazofamid, fenamidone, zoxamide, boscalid, cymoxanil, dithianon, fluazinam, dichlofluanide, triforine, isoprothiolane, ferimzone, diclomezine, tecloftalam, pencycuron, chinomethionat, iminoctadine acetate, iminoctadine albesilate, ambam, polycarbamate, thiadiazine, chloroneb, nickel dimethyldithiocarbamate, guazatine, dodecylguanidine-acetate, quintozene, tolylfluanid, anilazine, nitrothalisopropyl, fenitropan, dimethirimol, benthiazole, harpin protein, flumetover, mandipropamide and penthiopyrad. Polynucleotides As used herein, the term "DNA", "DNA molecule", "DNA polynucleotide molecule" refers to a single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) molecule of genomic or synthetic origin, such as, a polymer of deoxyribonucleotide bases or a DNA polynucleotide molecule. As used herein, the term "DNA sequence", "DNA nucleotide sequence" or "DNA polynucleotide sequence" refers to the nucleotide sequence of a DNA molecule. As used herein, the term "RNA", "RNA molecule", "RNA polynucleotide molecule" refers to a single-stranded RNA (ssRNA) or double-stranded RNA (dsRNA) molecule of genomic or synthetic origin, such as, a polymer of ribonucleotide bases that comprise single or double stranded regions. Unless otherwise stated, nucleotide sequences in the text of this specification are given, when read from left to right, in the 5' to 3' direction. The nomenclature 19 WO 2013/039990 PCT/US2012/054789 used herein is that required by Title 37 of the United States Code of Federal Regulations § 1.822 and set forth in the tables in WIPO Standard ST.25 (1998), Appendix 2, Tables 1 and 3. As used herein, "polynucleotide" refers to a DNA or RNA molecule containing multiple nucleotides and generally refers both to "oligonucleotides" (a polynucleotide molecule of typically 50 or fewer nucleotides in length) and polynucleotides of 51 or more nucleotides. Embodiments include compositions including oligonucleotides having a length of 18-25 nucleotides (18-mers, 19-mers, 20-mers, 21-mers, 22-mers, 23-mers, 24-mers, or 25-mers), for example, oligonucleotides SEQ ID NO:3223-3542 or fragments thereof or medium-length polynucleotides having a length of 26 or more nucleotides (polynucleotides of 26, 27, 28, 29, 30, 31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56, 57, 58, 59, 60, about 65, about 70, about 75, about 80, about 85, about 90, about 95, about 100, about 110, about 120, about 130, about 140, about 150, about 160, about 170, about 180, about 190, about 200, about 210, about 220, about 230, about 240, about 250, about 260, about 270, about 280, about 290, or about 300 nucleotides), for example, oligonucleotides SEQ ID NO: 121 3222 or fragments thereof or long polynucleotides having a length greater than about 300 nucleotides (for example, polynucleotides of between about 300 to about 400 nucleotides, between about 400 to about 500 nucleotides, between about 500 to about 600 nucleotides, between about 600 to about 700 nucleotides, between about 700 to about 800 nucleotides, between about 800 to about 900 nucleotides, between about 900 to about 1000 nucleotides, between about 300 to about 500 nucleotides, between about 300 to about 600 nucleotides, between about 300 to about 700 nucleotides, between about 300 to about 800 nucleotides, between about 300 to about 900 nucleotides, or about 1000 nucleotides in length, or even greater than about 1000 nucleotides in length, for example up to the entire length of a target gene including coding or non-coding or both coding and non-coding portions of the target gene), for example, polynucleotides of Table 1 (SEQ ID NO: 1-120), wherein the selected polynucleotides or fragments thereof are homologous or complementary to SEQ ID NO: 1-120 and suppresses, represses or otherwise delay the expression of the target EPSPS gene. Where a polynucleotide is double-stranded, its length can be similarly described in terms of base pairs. A target gene comprises any polynucleotide molecule in a plant cell or fragment thereof for which the modulation of the expression of the target gene is provided by the methods and compositions. A gene has noncoding genetic elements (components) that provide for the function of the gene, 20 WO 2013/039990 PCT/US2012/054789 these elements are polynucleotides that provide gene expression regulation, such as, a promoter, an enhancer, a 5' untranslated region, intron regions, and a 3' untranslated region. Oligonucleotides and polynucleotides can be made to any of the genetic elements of a gene and to polynucleotides spanning the junction region of a genetic element, such as, an intron and exon, the junction region of a promoter and a transcribed region, the junction region of a 5' leader and a coding sequence, the junction of a 3' untranslated region and a coding sequence. Polynucleotide compositions used in the various embodiments include compositions including oligonucleotides or polynucleotides or a mixture of both, including RNA or DNA or RNA/DNA hybrids or chemically modified oligonucleotides or polynucleotides or a mixture thereof. In some embodiments, the polynucleotide may be a combination of ribonucleotides and deoxyribonucleotides, for example, synthetic polynucleotides consisting mainly of ribonucleotides but with one or more terminal deoxyribonucleotides or synthetic polynucleotides consisting mainly of deoxyribonucleotides but with one or more terminal dideoxyribonucleotides. In some embodiments, the polynucleotide includes non-canonical nucleotides such as inosine, thiouridine, or pseudouridine. In some embodiments, the polynucleotide includes chemically modified nucleotides. Examples of chemically modified oligonucleotides or polynucleotides are well known in the art; see, for example, US Patent Publication 20110171287, US Patent Publication 20110171176, and US Patent Publication 20110152353, US Patent Publication, 20110152346, US Patent Publication 20110160082, herein incorporated in its entirety by reference hereto. For example, including but not limited to the naturally occurring phosphodiester backbone of an oligonucleotide or polynucleotide can be partially or completely modified with phosphorothioate, phosphorodithioate, or methylphosphonate internucleotide linkage modifications, modified nucleoside bases or modified sugars can be used in oligonucleotide or polynucleotide synthesis, and oligonucleotides or polynucleotides can be labeled with a fluorescent moiety (for example, fluorescein or rhodamine) or other label (for example, biotin). The polynucleotides can be single- or double-stranded RNA or single- or double-stranded DNA or double-stranded DNA/RNA hybrids or modified analogues thereof, and can be of oligonucleotide lengths or longer. In more specific embodiments, the polynucleotides that provide single-stranded RNA in the plant cell are selected from the group consisting of (a) a single-stranded RNA molecule (ssRNA), (b) a single-stranded RNA molecule that self 21 WO 2013/039990 PCT/US2012/054789 hybridizes to form a double-stranded RNA molecule, (c) a double-stranded RNA molecule (dsRNA), (d) a single-stranded DNA molecule (ssDNA), (e) a single-stranded DNA molecule that self-hybridizes to form a double-stranded DNA molecule, and (f) a single-stranded DNA molecule including a modified Pol III gene that is transcribed to an RNA molecule, (g) a double stranded DNA molecule (dsDNA), (h) a double-stranded DNA molecule including a modified Pol III gene that is transcribed to an RNA molecule, (i) a double-stranded, hybridized RNA/DNA molecule, or combinations thereof. In some embodiments these polynucleotides include chemically modified nucleotides or non-canonical nucleotides. In some embodiments, the oligonucleotides may be blunt-ended or may comprise a 3' overhang of from 1-5 nucleotides of at least one or both of the strands. Other configurations of the oligonucleotide are known in the field and are contemplated herein. In embodiments of the method the polynucleotides include double-stranded DNA formed by intramolecular hybridization, double-stranded DNA formed by intermolecular hybridization, double-stranded RNA formed by intramolecular hybridization, or double-stranded RNA formed by intermolecular hybridization. In one embodiment the polynucleotides include single-stranded DNA or single-stranded RNA that self-hybridizes to form a hairpin structure having an at least partially double-stranded structure including at least one segment that will hybridize to RNA transcribed from the gene targeted for suppression. Not intending to be bound by any mechanism, it is believed that such polynucleotides are or will produce single-stranded RNA with at least one segment that will hybridize to RNA transcribed from the gene targeted for suppression. In certain other embodiments the polynucleotides further includes a promoter, generally a promoter functional in a plant, for example, a pol II promoter, a pol III promoter, a pol IV promoter, or a pol V promoter. The term "gene" refers to components that comprise chromosomal DNA, plasmid DNA, cDNA, intron and exon DNA, artificial DNA polynucleotide, or other DNA that encodes a peptide, polypeptide, protein, or RNA transcript molecule, and the genetic elements flanking the coding sequence that are involved in the regulation of expression, such as, promoter regions, 5' leader regions, 3' untranslated region that may exist as native genes or transgenes in a plant genome. The gene or a fragment thereof is isolated and subjected to polynucleotide sequencing methods that determines the order of the nucleotides that comprise the gene. Any of the components of the gene are potential targets for a trigger oligonucleotide and polynucleotides. 22 WO 2013/039990 PCT/US2012/054789 The trigger polynucleotide molecules are designed to modulate expression by inducing regulation or suppression of an endogenous EPSPS gene in a plant and are designed to have a nucleotide sequence essentially identical or essentially complementary to the nucleotide sequence of an endogenous EPSPS gene of a plant or to the sequence of RNA transcribed from an endogenous EPSPS gene of a plant, the sequence thereof determined by isolating the gene or a fragment of the gene from the plant, which can be coding sequence or non-coding sequence. Effective molecules that modulate expression are referred to as "a trigger molecule, or trigger polynucleotide". By "essentially identical" or "essentially complementary" is meant that the trigger polynucleotides (or at least one strand of a double-stranded polynucleotide or portion thereof, or a portion of a single strand polynucleotide) are designed to hybridize to the endogenous gene noncoding sequence or to RNA transcribed (known as messenger RNA or an RNA transcript) from the endogenous gene to effect regulation or suppression of expression of the endogenous gene. Trigger molecules are identified by "tiling" the gene targets with partially overlapping probes or non-overlapping probes of antisense or sense polynucleotides that are essentially identical or essentially complementary to the nucleotide sequence of an endogenous gene. Multiple target sequences can be aligned and sequence regions with homology in common, according to the methods, are identified as potential trigger molecules for the multiple targets. Multiple trigger molecules of various lengths, for example 18-25 nucleotides, 26-50 nucleotides, 5 1-100 nucleotides, 101-200 nucleotides, 201-300 nucleotides or more can be pooled into a few treatments in order to investigate polynucleotide molecules that cover a portion of a gene sequence (for example, a portion of a coding versus a portion of a noncoding region, or a 5' versus a 3' portion of a gene) or an entire gene sequence including coding and noncoding regions of a target gene. Polynucleotide molecules of the pooled trigger molecules can be divided into smaller pools or single molecules inorder to identify trigger molecules that provide the desired effect. The target gene RNA and DNA polynucleotide molecules (Table 1, SEQ ID NO: 1-120) are sequenced by any number of available methods and equipment. Some of the sequencing technologies are available commercially, such as the sequencing-by-hybridization platform from Affymetrix Inc. (Sunnyvale, Calif.) and the sequencing-by-synthesis platforms from 454 Life Sciences (Bradford, Conn.), Illumina/Solexa (Hayward, Calif.) and Helicos Biosciences (Cambridge, Mass.), and the sequencing-by-ligation platform from Applied Biosystems (Foster 23 WO 2013/039990 PCT/US2012/054789 City, Calif.), as described below. In addition to the single molecule sequencing performed using sequencing-by-synthesis of Helicos Biosciences, other single molecule sequencing technologies are encompassed and include the SMRTTM. technology of Pacific Biosciences, the Ion TorrentTM. technology, and nanopore sequencing being developed for example, by Oxford Nanopore Technologies. An EPSPS target gene comprising DNA or RNA can be isolated using primers or probes essentially complementary or essentially homologous to SEQ ID NO: 1-120 or a fragment thereof. A polymerase chain reaction (PCR) gene fragment can be produced using primers essentially complementary or essentially homologous to SEQ ID NO: 1-120 or a fragment thereof that is useful to isolate an EPSPS gene from a plant genome. SEQ ID NO: 1-120 or fragments thereof can be used in various sequence capture technologies to isolate additional target gene sequences, for example, including but not limited to Roche NimbleGen@ (Madison, WI) and Streptavdin-coupled Dynabeads@ (Life Technologies, Grand Island, NY) and US20110015084, herein incorporated by reference in its entirety. Embodiments of functional single-stranded polynucleotides have sequence complementarity that need not be 100 percent, but is at least sufficient to permit hybridization to RNA transcribed from the target gene or DNA of the target gene to form a duplex to permit a gene silencing mechanism. Thus, in embodiments, a polynucleotide fragment is designed to be essentially identical to, or essentially complementary to, a sequence of 18 or more contiguous nucleotides in either the target EPSPS gene sequence or messenger RNA transcribed from the target gene. By "essentially identical" is meant having 100 percent sequence identity or at least about 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 percent sequence identity when compared to the sequence of 18 or more contiguous nucleotides in either the target gene or RNA transcribed from the target gene; by "essentially complementary" is meant having 100 percent sequence complementarity or at least about 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 percent sequence complementarity when compared to the sequence of 18 or more contiguous nucleotides in either the target gene or RNA transcribed from the target gene. In some embodiments, polynucleotide molecules are designed to have 100 percent sequence identity with or complementarity to one allele or one family member of a given target gene (coding or non-coding sequence of a gene); in other embodiments the polynucleotide molecules are designed to have 100 percent sequence identity with or complementarity to multiple alleles or family members of a given target gene. 24 WO 2013/039990 PCT/US2012/054789 "Identity" refers to the degree of similarity between two polynucleic acid or protein sequences. An alignment of the two sequences is performed by a suitable computer program. A widely used and accepted computer program for performing sequence alignments is CLUSTALW v1.6 (Thompson, et al. Nucl. Acids Res., 22: 4673-4680, 1994). The number of matching bases or amino acids is divided by the total number of bases or amino acids, and multiplied by 100 to obtain a percent identity. For example, if two 580 base pair sequences had 145 matched bases, they would be 25 percent identical. If the two compared sequences are of different lengths, the number of matches is divided by the shorter of the two lengths. For example, if there are 100 matched amino acids between a 200 and a 400 amino acid protein, they are 50 percent identical with respect to the shorter sequence. If the shorter sequence is less than 150 bases or 50 amino acids in length, the number of matches are divided by 150 (for nucleic acid bases) or 50 (for amino acids), and multiplied by 100 to obtain a percent identity. Trigger molecules for specific gene family members can be identified from coding and/or non-coding sequences of gene families of a plant or multiple plants, by aligning and selecting 200-300 polynucleotide fragments from the least homologous regions amongst the aligned sequences and evaluated using topically applied polynucleotides (as sense or anti-sense ssDNA or ssRNA, dsRNA, or dsDNA) to determine their relative effectiveness in providing the herbicidal phenotype. The effective segments are further subdivided into 50-60 polynucleotide fragments, prioritized by least homology, and reevaluated using topically applied polynucleotides. The effective 50-60 polynucleotide fragments are subdivided into 19-30 polynucleotide fragments, prioritized by least homology, and again evaluated for induction of the herbicidal phenotype. Once relative effectiveness is determined, the fragments are utilized singly, or again evaluated in combination with one or more other fragments to determine the trigger composition or mixture of trigger polynucleotides for providing the herbicidal phenotype. Trigger molecules for broad activity can be identified from coding and/or non-coding sequences of gene families of a plant or multiple plants, by aligning and selecting 200-300 polynucleotide fragments from the most homologous regions amongst the aligned sequences and evaluated using topically applied polynucleotides (as sense or anti-sense ssDNA or ssRNA, dsRNA, or dsDNA) to determine their relative effectiveness in inducing the herbicidal phenotype. The effective segments are subdivided into 50-60 polynucleotide fragments, prioritized by most homology, and reevaluated using topically applied polynucleotides. The 25 WO 2013/039990 PCT/US2012/054789 effective 50-60 polynucleotide fragments are subdivided into 19-30 polynucleotide fragments, prioritized by most homology, and again evaluated for induction of the herbicidal phenotype. Once relative effectiveness is determined, the fragments may be utilized singly, or in combination with one or more other fragments to determine the trigger composition or mixture of trigger polynucleotides for providing the herbicidal phenotype. Methods of making polynucleotides are well known in the art. Chemical synthesis, in vivo synthesis and in vitro synthesis methods and compositions are known in the art and include various viral elements, microbial cells, modified polymerases, and modified nucleotides. Commercial preparation of oligonucleotides often provides two deoxyribonucleotides on the 3' end of the sense strand. Long polynucleotide molecules can be synthesized from commercially available kits, for example, kits from Applied Biosystems/Ambion (Austin, TX) have DNA ligated on the 5' end in a microbial expression cassette that includes a bacterial T7 polymerase promoter that makes RNA strands that can be assembled into a dsRNA and kits provided by vaious manufacturers that include T7 RiboMax Express (Promega, Madison, WI), AmpliScribe T7-Flash (Epicentre, Madison, WI), and TranscriptAid T7 High Yield (Fermentas, Glen Burnie, MD). dsRNA molecules can be produced from microbial expression cassettes in bacterial cells (Ongvarrasopone et al. ScienceAsia 33:35-39; Yin, Appl. Microbiol. Biotechnol 84:323-333, 2009; Liu et al., BMC Biotechnology 10:85, 2010) that have regulated or deficient RNase III enzyme activity or the use of various viral vectors to produce sufficient quantities of dsRNA. EPSPS gene fragments are inserted into the microbial expression cassettes in a position in which the fragments are express to produce ssRNA or dsRNA useful in the methods described herein to regulate expression on a target EPSPS gene. Long polynucleotide molecules can also be assembled from multiple RNA or DNA fragments. In some embodiments design parameters such as Reynolds score (Reynolds et al. Nature Biotechnology 22, 326 - 330 (2004),Tuschl rules (Pei and Tuschl, Nature Methods 3(9): 670-676, 2006), i-score (Nucleic Acids Res 35: e123, 2007), i-Score Designer tool and associated algorithms (Nucleic Acids Res 32: 936-948, 2004. Biochem Biophys Res Commun 316: 1050-1058, 2004, Nucleic Acids Res 32: 893-901, 2004, Cell Cycle 3: 790-5, 2004, Nat Biotechnol 23: 995-1001, 2005, Nucleic Acids Res 35: e27, 2007, BMC Bioinformatics 7: 520, 2006, Nucleic Acids Res 35: e123, 2007, Nat Biotechnol 22: 326-330, 2004) are known in the art and may be used in selecting polynucleotide sequences effective in gene silencing. In some embodiments the sequence of a polynucleotide is screened 26 WO 2013/039990 PCT/US2012/054789 against the genomic DNA of the intended plant to minimize unintentional silencing of other genes. Ligands can be tethered to a polynucleotide, for example a dsRNA, ssRNA, dsDNA or ssDNA. Ligands in general can include modifiers, e.g., for enhancing uptake; diagnostic compounds or reporter groups e.g., for monitoring distribution; cross-linking agents; nuclease resistance conferring moieties; and natural or unusual nucleobases. General examples include lipophiles, lipids (e.g., cholesterol, a bile acid, or a fatty acid (e.g., lithocholic-oleyl, lauroyl, docosnyl, stearoyl, palmitoyl, myristoyl oleoyl, linoleoyl), steroids (e.g., uvaol, hecigenin, diosgenin), terpenes (e.g., triterpenes, e.g., sarsasapogenin, Friedelin, epifriedelanol derivatized lithocholic acid), vitamins (e.g., folic acid, vitamin A, biotin, pyridoxal), carbohydrates, proteins, protein binding agents, integrin targeting molecules, polycationics, peptides, polyamines, and peptide mimics. The ligand may also be a recombinant or synthetic molecule, such as a synthetic polymer, e.g., polyethylene glycol (PEG), PEG-40K, PEG-20K and PEG-5K. Other examples of ligands include lipophilic molecules, e.g, cholesterol, cholic acid, adamantane acetic acid, 1 pyrene butyric acid, dihydrotestosterone, glycerol (e.g., esters and ethers thereof, e.g., C.sub. 10, C.sub.11, C.sub.12, C.sub.13, C.sub.14, C.sub.15, C.sub.16, C.sub.17, C.sub.18, C.sub.19, or C.sub.20 alkyl; e.g., lauroyl, docosnyl, stearoyl, oleoyl, linoleoyl 1,3-bis-O(hexadecyl)glycerol, 1,3-bis-O(octaadecyl)glycerol), geranyloxyhexyl group, hexadecylglycerol, borneol, menthol, 1,3-propanediol, heptadecyl group, palmitic acid, myristic acid, 03-(oleoyl)lithocholic acid, 03 (oleoyl)cholenic acid, dodecanoyl, lithocholyl, 5.beta.-cholanyl, N,N-distearyl-lithocholamide, 1,2-di-O-stearoylglyceride, dimethoxytrityl, or phenoxazine) and PEG (e.g., PEG-5K, PEG-20K, PEG-40K). Preferred lipophilic moieties include lipid, cholesterols, oleyl, retinyl, or cholesteryl residues. Conjugating a ligand to a dsRNA can enhance its cellular absorption, lipophilic compounds that have been conjugated to oligonucleotides include 1-pyrene butyric acid, 1,3-bis O-(hexadecyl)glycerol, and menthol. One example of a ligand for receptor-mediated endocytosis is folic acid. Folic acid enters the cell by folate-receptor-radiated endocytosis. dsRNA compounds bearing folic acid would be efficiently transported into the cell via the folate receptor-mediated endocytosis. Other ligands that have been conjugated to oligonucleotides include polyethylene glycols, carbohydrate clusters, cross-linking agents, porphyrin conjugates, delivery peptides and lipids such as cholesterol. In certain instances, conjugation of a cationic 27 WO 2013/039990 PCT/US2012/054789 ligand to oligonucleotides results in improved resistance to nucleases. Representative examples of cationic ligands are propylammonium and dimethylpropylammonium. Interestingly, antisense oligonucleotides were reported to retain their high binding affinity to mRNA when the cationic ligand was dispersed, throughout the oligonucleotide. See M. Manoharan Antisense & Nucleic Acid Drug Development 2002, 12, 103 and references therein. A biologic delivery can be accomplished by a variety of methods including, without limitation, (1) loading liposomes with a dsRNA acid molecule provided herein and (2) complexing a dsRNA molecule with lipids or liposomes to form nucleic acid-lipid or nucleic acid-liposome complexes. The liposome can be composed of cationic and neutral lipids commonly used to transfect cells in vitro. Cationic lipids can complex (e.g., charge-associate) with negatively charged, nucleic acids to form liposomes. Examples of cationic liposomes include, without limitation, lipofectin, lipofectamine, lipofectace, and DOTAP. Procedures for forming liposomes are well known in the art. Liposome compositions can be formed, for example, from phosphatidylcholine, dimyristoyl phosphatidylcholine, dipalmitoyl phosphatidylcholine, dimyristoyl phosphatidyl glycerol, dioleoyl phosphatidylethanolamine or liposomes comprising dihydrosphingomyelin (DHSM) Numerous lipophilic agents are commercially available, including Lipofectin@ (Invitrogen/Life Technologies, Carlsbad, Calif.) and EffecteneTM (Qiagen, Valencia, Calif.), In addition, systemic delivery methods can be optimized using commercially available cationic lipids such as DDAB or DOTAP, each of which can be mixed with a neutral lipid such as DOPE or cholesterol. In some eases, liposomes such as those described by Templeton et al. (Nature Biotechnology, 15:647-652 (1997)) can be used. In other embodiments, polycations such as polyethyleneimine can be used to achieve delivery in vivo and ex vivo (Boletta et al., J. Am Soc. Nephrol. 7:1728 (1996)). Additional information regarding the use of liposomes to deliver nucleic acids can be found in U.S. Pat. No. 6,271,359, PCT Publication WO 96/40964 and Morrissey, D. et al. 2005. Nat Biotechnol. 23(8):1002-7. In certain embodiments, an organosilicone preparation that is commercially available as Silwet@ L-77 surfactant having CAS Number 27306-78-1 and EPA Number: CAL.REG.NO. 5905-50073-AA, and currently available from Momentive Performance Materials, Albany, New York can be used to prepare a polynucleotide composition. In certain embodiments where a Silwet L-77 organosilicone preparation is used as a pre-spray treatment of plant leaves or other plant surfaces, freshly made concentrations in the range of about 0.0 15 to about 2 percent by 28 WO 2013/039990 PCT/US2012/054789 weight (wt percent) (e. g., about 0.01, 0.015, 0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05, 0.055, 0.06, 0.065, 0.07, 0.075, 0.08, 0.085, 0.09, 0.095, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.5 wt percent) are efficacious in preparing a leaf or other plant surface for transfer of polynucleotide molecules into plant cells from a topical application on the surface. In certain embodiments of the methods and compositions provided herein, a composition that comprises a polynucleotide molecule and an organosilicone preparation comprising Silwet L-77 in the range of about 0.015 to about 2 percent by weight (wt percent) (e. g., about 0.01, 0.015, 0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05, 0.055, 0.06, 0.065, 0.07, 0.075, 0.08, 0.085, 0.09, 0.095, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.5 wt percent) is used or provided. In certain embodiments, any of the commercially available organosilicone preparations provided such as the following Breakthru S 321, Breakthru S 200 Cat# 67674-67-3, Breakthru OE 441 Cat#68937-55-3, Breakthru S 278 Cat #27306-78-1, Breakthru S 243, Breakthru S 233 Cat#134180-76-0, available from manufacturer Evonik Goldschmidt (Germany), Silwet@ HS 429, Silwet@ HS 312, Silwet@ HS 508, Silwet@ HS 604 (Momentive Performance Materials, Albany, New York) can be used as transfer agents in a polynucleotide composition. In certain embodiments where an organosilicone preparation is used as a pre-spray treatment of plant leaves or other surfaces, freshly made concentrations in the range of about 0.015 to about 2 percent by weight (wt percent) (e. g., about 0.01, 0.015, 0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05, 0.055, 0.06, 0.065, 0.07, 0.075, 0.08, 0.085, 0.09, 0.095, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.5 wt percent) are efficacious in preparing a leaf or other plant surface for transfer of polynucleotide molecules into plant cells from a topical application on the surface. In certain embodiments of the methods and compositions provided herein, a composition that comprises a polynucleotide molecule and an organosilicone preparation in the range of about 0.015 to about 2 percent by weight (wt percent) (e. g., about 0.01, 0.015, 0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05, 0.055, 0.06, 0.065, 0.07, 0.075, 0.08, 0.085, 0.09, 0.095, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.5 wt percent) is used or provided. Organosilicone preparations used in the methods and compositions provided herein can comprise one or more effective organosilicone compounds. As used herein, the phrase "effective organosilicone compound" is used to describe any organosilicone compound that is found in an 29 WO 2013/039990 PCT/US2012/054789 organosilicone preparation that enables a polynucleotide to enter a plant cell. In certain embodiments, an effective organosilicone compound can enable a polynucleotide to enter a plant cell in a manner permitting a polynucleotide mediated suppression of a target gene expression in the plant cell. In general, effective organosilicone compounds include, but are not limited to, compounds that can comprise: i) a trisiloxane head group that is covalently linked to, ii) an alkyl linker including, but not limited to, an n-propyl linker, that is covalently linked to, iii) a poly glycol chain, that is covalently linked to, iv) a terminal group. Trisiloxane head groups of such effective organosilicone compounds include, but are not limited to, heptamethyltrisiloxane. Alkyl linkers can include, but are not limited to, an n-propyl linker. Poly glycol chains include, but are not limited to, polyethylene glycol or polypropylene glycol. Poly glycol chains can comprise a mixture that provides an average chain length "n" of about "7.5". In certain embodiments, the average chain length "n" can vary from about 5 to about 14. Terminal groups can include, but are not limited to, alkyl groups such as a methyl group. Effective organosilicone compounds are believed to include, but are not limited to, trisiloxane ethoxylate surfactants or polyalkylene oxide modified heptamethyl trisiloxane. Si n (Compound I: polyalkyleneoxide heptamethyltrisiloxane, average n=7.5). In certain embodiments, an organosilicone preparation that comprises an organosilicone compound comprising a trisiloxane head group is used in the methods and compositions provided herein. In certain embodiments, an organosilicone preparation that comprises an organosilicone compound comprising a heptamethyltrisiloxane head group is used in the methods and compositions provided herein. In certain embodiments, an organosilicone composition that comprises Compound I is used in the methods and compositions provided herein. In certain embodiments, an organosilicone composition that comprises Compound I is used in the methods and compositions provided herein. In certain embodiments of the methods 30 WO 2013/039990 PCT/US2012/054789 and compositions provided herein, a composition that comprises a polynucleotide molecule and one or more effective organosilicone compound in the range of about 0.015 to about 2 percent by weight (wt percent) (e. g., about 0.01, 0.015, 0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05, 0.055, 0.06, 0.065, 0.07, 0.075, 0.08, 0.085, 0.09, 0.095, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.5 wt percent) is used or provided. Compositions include but are not limited components that are one or more polynucleotides essentially identical to, or essentially complementary to an EPSPS gene sequence (promoter, intron, exon, 5' untranslated region, 3' untranslated region), a transfer agent that provides for the polynucleotide to enter a plant cell, a herbicide that complements the action of the polynucleotide, one or more additional herbicides that further enhance the herbicide activity of the composition or provide an additional mode of action different from the complementing herbicide, various salts and stabilizing agents that enhance the utility of the composition as an admixture of the components of the composition. In certain aspects, methods include one or more applications of a polynucleotide composition and one or more applications of a transfer agent for conditioning of a plant to permeation by polynucleotides. When the agent for conditioning to permeation is an organosilicone composition or compound contained therein, embodiments of the polynucleotide molecules are double-stranded RNA oligonucleotides, single-stranded RNA oligonucleotides, double-stranded RNA polynucleotides, single-stranded RNA polynucleotides, double-stranded DNA oligonucleotides, single-stranded DNA oligonucleotides, double-stranded DNA polynucleotides, single-stranded DNA polynucleotides, chemically modified RNA or DNA oligonucleotides or polynucleotides or mixtures thereof. Compositions and methods are useful for modulating the expression of an endogenous EPSPS gene or transgenic EPSPS gene (for example, CP4 EPSPS, U.S. Pat. No. RE39,247 and 2mEPSPS, U.S. Pat. No. 6,040,497) gene in a plant cell. In various embodiments, an EPSPS gene includes coding (protein-coding or translatable) sequence, non-coding (non-translatable) sequence, or both coding and non-coding sequence. Compositions can include polynucleotides and oligonucleotides designed to target multiple genes, or multiple segments of one or more genes. The target gene can include multiple consecutive segments of a target gene, multiple non consecutive segments of a target gene, multiple alleles of a target gene, or multiple target genes from one or more species. 31 WO 2013/039990 PCT/US2012/054789 Provided is a method for modulating expression of an EPSPS gene in a plant including (a) conditioning of a plant to permeation by polynucleotides and (b) treatment of the plant with the polynucleotide molecules, wherein the polynucleotide molecules include at least one segment of 18 or more contiguous nucleotides cloned from or otherwise identified from the target EPSPS gene in either anti-sense or sense orientation, whereby the polynucleotide molecules permeate the interior of the plant and induce modulation of the target gene. The conditioning and polynucleotide application can be performed separately or in a single step. When the conditioning and polynucleotide application are performed in separate steps, the conditioning can precede or can follow the polynucleotide application within minutes, hours, or days. In some embodiments more than one conditioning step or more than one polynucleotide molecule application can be performed on the same plant. In embodiments of the method, the segment can be cloned or identified from (a) coding (protein-encoding), (b) non-coding (promoter and other gene related molecules), or (c) both coding and non-coding parts of the target gene. Non-coding parts include DNA, such as promoter regions or the RNA transcribed by the DNA that provide RNA regulatory molecules, including but not limited to: introns, 5' or 3' untranslated regions, and microRNAs (miRNA), trans-acting siRNAs, natural anti-sense siRNAs, and other small RNAs with regulatory function or RNAs having structural or enzymatic function including but not limited to: ribozymes, ribosomal RNAs, t-RNAs, aptamers, and riboswitches. All publications, patents and patent applications are herein incorporated by reference to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference. The following examples are included to demonstrate examples of certain preferred embodiments. It should be appreciated by those of skill in the art that the techniques disclosed in the examples that follow represent approaches the inventors have found function well in the practice, and thus can be considered to constitute examples of preferred modes for its practice. However, those of skill in the art should, in light of the present disclosure, appreciate that many changes can be made in the specific embodiments that are disclosed and still obtain a like or similar result without departing from the spirit and scope. EXAMPLES Example 1. Polynucleotides related to the EPSPS gene sequences. 32 WO 2013/039990 PCT/US2012/054789 The target EPSPS gene polynucleotide molecules have been found that naturally occur in the genome of Amaranthus palmeri, Amaranthus rudis, Amaranthus graecizans, Amaranthus hybridus, Amaranthus lividus, Amaranthus spinosus, Amaranthus thunbergii, Amaranthus viridis, Lolium multiflorum, Lolium rigidium, Ambrosia artemisiifolia, Ambrosia trifida, Euphorbia heterophylla, Kochia scoparia, Abutilon theophrasti, Sorghum halepense, Chenopodium album, Commelina diffusa, Conyza candensis, Digitaria sanguinalis, and include molecules related to the expression of a polypeptide identified as an EPSPS, that include regulatory molecules, cDNAs comprising coding and noncoding regions of an EPSPS gene and fragments of the plant genes thereof as shown in Table 1. Additionally, the EPSPS gene coding sequence isolated from Agrobacterium tumefaciens that encodes for a glyphosate resistant EPSPS enzyme and that is commonly used to produce glyphosate resistant crop plants is shown in SEQ ID NO: 1 in Table 1. Polynucleotide molecules were extracted from these plant species by methods standard in the field, for example, total RNA was extracted using Trizol Reagent (Invitrogen Corp, Carlsbad, CA Cat. No. 15596-018), following the manufacturer's protocol or modifications thereof by those skilled in the art of polynucleotide extraction that may enhance recover or purity of the extracted RNA. Briefly, start with 1 gram of ground plant tissue for extraction. Prealiquot 10 milliliters (mL) Trizol reagent to 15 mL conical tubes. Add ground powder to tubes and shake to homogenize. Incubate the homogenized samples for 5 minutes (min) at room temperature (RT) and then add 3 mL of chloroform. Shakes tubes vigorously by hand for 15-30 seconds(sec) and incubate at RT for 3 min. Centrifuge the tubes at 7,000 revolutions per minute (rpm) for 10 min at 4 degrees C. Transfer the aqueous phase to a new 1.5 mL tube and add 1 volume of cold isopropanol. Incubate the samples for 20-30 min at RT and centrifuge at 10,000 rpm for 10 min at 4 degrees C. Wash pellet with Sigma-grade 80 percent ethanol. Remove the supernatant and briefly air-dry the pellet. Dissolve the RNA pellet in approximately 200 microliters of DEPC treated water. Heat briefly at 65 degrees C to dissolve pellet and vortex or pipet to resuspend RNA pellet. Adjust RNA concentraiton to 1-2 microgram/microliter. DNA was extracted using EZNA SP Plant DNA Mini kit (Omega Biotek, Norcross GA, Cat#D55 11) and Lysing Matrix E tubes (Q-Biogen, Cat#6914), following the manufacturer's protocol or modifications thereof by those skilled in the art of polynucleotide extraction that may enhance recover or purity of the extracted DNA. Briefly, aliquot ground tissue to a Lysing 33 WO 2013/039990 PCT/US2012/054789 Matrix E tube on dry ice, add 800 1 Buffer SPI to each sample, homogenize in a bead beater for 35-45sec, incubate on ice for 45-60 sec, centrifuge at >14000 rpm for 1min at RT, add 10 microliter RNase A to the lysate, incubate at 65'C for 10min, centrifuge for 1min at RT, add 280 1 Buffer SP2 and vortex to mix, incubate the samples on ice for 5min, centrifuge at >10,000g for 10min at RT, transfer the supernatant to a homogenizer column in a 2ml collection tube, centrifuge at 10,000g for 2min at RT, transfer the cleared lysate into a 1.5ml microfuge tube, add 1.5 volumes Buffer SP3 to the cleared lysate, vortex immediately to obtain a homogeneous mixture, transfer up to 650 1 supernatant to the Hi-Bind column, centrifuge at 10,000g for 1min, repeat, apply 100 1 65'C Elution Buffer to the column, centrifuge at 10,000g for 5min at RT. Next-generation DNA sequencers, such as the 454-FLX (Roche, Branford, CT), the SOLiD (Applied Biosystems), and the Genome Analyzer (HiSeq2000, Illumina, San Diego, CA) were used to provide polynucleotide sequence from the DNA and RNA extracted from the plant tissues. Raw sequence data was assembled into contigs as illustrated in Table 1 and SEQ ID NO: 2-120. The contig sequence was used to identify trigger molecules that can be applied to the plant to enable regulation of the gene expression. Example 2. Polynucleotides related to the trigger molecules The gene sequences and fragments of Table 1 were divided into 200 polynucleotide (200 mer) lengths with 25 polynucleotide overlapping regions (SEQ ID NO: 121-3222). These polynucleotides are tested to select the most efficacious trigger regions across the length of any target sequence. The trigger polynucleotides are constructed as sense or anti-sense ssDNA or ssRNA, dsRNA, or dsDNA, or dsDNA/RNA hybrids and combined with an organosilicone based transfer agent to provide a polynucleotide preparation. The polynucleotides are combined into sets of two to three polynucleotides per set, using 4-8 nmol of each polynucleotide. Each polynucleotide set is prepared with the transfer agent and applied to a plant or a field of plants in combination with a glyphosate containing herbicide, or followed by a glyphosate treatment one to three days after the polynucleotide application, to determine the effect on the plant's susceptibility to glyphosate. The effect is measured as stunting the growth and/or killing of the plant and is measured 8-14 days after treatment with the polynucleotide set and glyphosate. The most efficacious sets are identified and the individual polynucleotides are tested in the same 34 WO 2013/039990 PCT/US2012/054789 methods as the sets are and the most efficacious single 200-mer identified. The 200-mer sequence is divided into smaller sequences of 50-70-mer regions with 10-15 polynucleotide overlapping regions and the polynucleotides tested individually. The most efficacious 50-70-mer is further divided into smaller sequences of 25-mer regions with a 12 to 13 polynucleotide overlapping region and tested for efficacy in combination with glyphosate treatment. By this method it is possible to identify an oligonucleotide or several oligonucleotides that are the most efficacious trigger molecule to effect plant sensitivity to glyphosate or modulation of EPSPS gene expression. The modulation of EPSPS gene expression is determined by the detection of EPSPS siRNA moleclules specific to EPSPS gene or by an observation of a reduction in the amount of EPSPS RNA transcript produced relative to an untreated plant or by merely observing the anticipated phenotype of the application of the trigger with the glyphosate containing herbicide. Detection of siRNA can be accomplished, for example, using kits such as mirVana (Ambion, Austin TX) and mirPremier (Sigma-Aldrich, St Louis, MO). The gene sequences and fragments of Table 1 were compared and 21-mers of contiguous polynucleotides were identified that have homology across the various EPSPS gene sequences (SEQ ID NO: 1-120). The purpose was to identify trigger molecules that are useful as herbicidal molecules or in combination with glyphosate herbicide enhance effective weed control across a broad range of weed species including glyphosate resistant weed biotypes. SEQ ID NO: 3223 3542 represent the 21-mers that are present in the EPSPS gene of at least eight of the weed species of Table 1. It is contemplated that additional 21-mers can be selected from the sequences of Table 1 that are specific for a single weed species or a few weeds species within a genus or trigger molecules that are at least 18 contiguous nucleotides, at least 19 contiguous nucleotides, at least 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO:1-120 or fragments thereof. The 21-mer oligonucleotides are combined into a 6-12 oligonucleotide set and tested for efficacy against the broadest range of weed species in which the oligonucleotide is essentially identical or essentially complementary to the EPSPS gene sequence in the genome of the weed species. Efficacious sets are divided into smaller sets of 2-3 oligonucleotides and tested for efficacy. Each polynucleotide set is prepared with the transfer agent and applied to a plant or a field of plants in combination with a glyphosate containing herbicide, or followed by a glyphosate treatment one to three days after the oligonucleotide 35 WO 2013/039990 PCT/US2012/054789 application, to determine the effect in the plant's susceptibility to glyphosate. The effect is measured as stunting the growth and/or killing of the plant and is measured 8-14 days after treatment with the polynucleotide set and glyphosate. By this method it is possible to identify an oligonucleotide or several oligonucleotides that are the most efficacious trigger molecule to effect plant sensitivity to glyphosate or modulation of EPSPS gene expression. The modulation of EPSPS gene expression is determined by the detection of EPSPS siRNA moleclules specific to EPSPS gene or by an observation of a reduction in the amount of EPSPS RNA transcript produced relative to an untreated plant. Detection of siRNA can be accomplished, for example, using kits such as mirVana (Ambion, Austin TX) and mirPremier (Sigma-Aldrich, St Louis, MO). Example 3. Methods related to treating plants or plant parts with a topical mixture of the modified trigger oligonucleotide molecules. Single stranded or double stranded DNA or RNA fragments in sense or antisense orientation or both were identified and mixed with a transfer agent and other components in the composition. This composition was topically applied to plants to effect expression of the target EPSPS genes in the specified plant to obtain the desired effect on growth or development. In this example, growing Amaranthus palmeri plants were treated with a topically applied composition for inducing modulation of a target gene in a plant including (a) an agent for conditioning of a plant to permeation by polynucleotides and (b) polynucleotides including at least one polynucleotide strand including at least one segment of 17-25 contiguous nucleotides of the target gene in either anti-sense (AS) or sense (S) orientation. Amaranthus palmeri plants were treated with a topically applied adjuvant solution comprising dsRNA, ssDNA, and DNA/RNA hybrid polynucleotides shown in Table 2 (SEQ ID NO: 3544-3587, respectively) essentially homologous or essentially complementary to the Amaranthus palmeri EPSPS coding sequence. The polynucleotide sequences of the trigger molecules used in each treatment are shown in column 2. The trigger molecules, 5.2-RNA-M1 through M6 are modified for mismatch nucleotides (n) relative to 5.2.RNA-wt (wildtype). The type of polynucleotide for each trigger is shown in column 3, its' length in column 4 and the results observed in column 5. The results are expressed as a relative measure of activity, the tested oligonucleotide was either active, less active, or inactive in the bioassay. 36 WO 2013/039990 PCT/US2012/054789 A trigger sequence was identified to target the EPSPS promoter of glyphosate resistant Amaranthus palmeri and tests conducted to determine some activities of the trigger identified as AS83 (SEQ ID NO: 3670). The trigger sequence was made as ssDNA, dsDNA or dsRNA and various 3' and 5' deletions of AS83 were tested along with internal mismatch mutations. The following procedure was used for all assays described in this example. Approximately four-week old Amaranthus palmeri plants (glyphosate-resistant Palmer amaranth, "R-22") were used in this assay. Plants were treated with 0.1% Silwet L-77 solution freshly made with ddH20. Two fully expanded leaves per plant (one cotyledon, one true leaf) awere treated with the polynucleotide/Silwet L-77 solution. Final concentration for each oligonucleotide or polynucleotide was 25 microM (in 0.0 1% Silwet L-77, 5 mM sodium phosphate buffer, pH 6.8) unless otherwise stated. Twenty microliters of the solution was applied to the top surface of each of the two pre-treated leaves to provide a total of 40 microliters (1 nmol oligonucleotide or polynucleotide) for each plant. Spray solutions were prepared the same day as spraying. Single oligonucleotide molecules shown in Table 2 and Table 4 were applied at rates between 0.04 and 0.18 mg/ml in 20 mM potassium phosphate buffer (pH 6.8) are added to spray solutions 15 to 50 minutes before spraying. One-to-two-ml spray solutions were applied using a custom low-dead-volume sprayer ("milli applicator") at 8-30 gpa (gallons per acre) to one-to-four inch tall plants. Treated plants were place in a greenhouse set for either a 26.7/21.1 C or 29.4/21.1 C 14/10 hour temperature and supplemental light schedule. The amount of response relative to unsprayed treatments was collected at various time intervals up to 21 days after treatment. The current default spray nozzle used for all applications made with the track sprayer is the Turbo Teejet air induction nozzle (015) nozzle with air pressure set at a minimum of 20 psi (160kpa). The height of the spray nozzle was 16-18 inches above top of plant material. Treatments were made when plants reach the desired size, height or leaf stage. Application rates are chosen so as to achieve percent control ratings in the range of 50% at the lowest rate to 90% control at the highest rate. The rates in this control range provide the best possible efficacy comparisons among formulations, allowing separation of relative performance of test samples. The rate of glyphosate used in these studies is typically held constant at 1680g ae/ha (grams acid equivalent/hectare). On occasion lower or higher rates may be necessary depending on test objectives. The rate structure used for a given test will be 37 WO 2013/039990 PCT/US2012/054789 dependent on the environmental conditions at the time of spray application (time of year), the plant species being treated (highly susceptible or tough to kill) and age (or size) of plants to be treated. These results illustrated in Table 2 shows that dsRNA, dsDNA and ssDNA were effective oligonucleotides trigger molecules for activity against EPSPS gene exon coding sequence and noncoding (promoter) sequence. Generally, 3 mismatches in a 21-mer or about 85 percent sequence homology can be tolerated, oligonucleotides shorter than 21 appear to have less activity in this assay Other modifications, such as the addition of some 3' synthetic nucleotides (ddC and IdT) did not seem to be tolerated in this bioassay. Table 2. Various polynucleotide types and modified sequence homologies 1. Oligo name 2. Sequence (AS strand, unless 3. Type 4.length 5.Activity otherwise indicated) 5.2-RNA-wt GTC ATA GCA ACA TCT GGC dsRNA 21 active ATT 5.2-DNA-wt GTC ATA GCA ACA TCT GGC dsDNA 21 active ATT 5.2-ssDNA-S AAT GCC AGA TGT TGC TAT ssDNA 21 less active GAC 5.2-ssDNA-AS GTC ATA GCA ACA TCT GGC ssDNA 21 less active ATT 5.2-sDNA/asRNA GTC ATA GCA ACA TCT GGC DNA/RNA 21 inactive ATT hybrid 5.2-asDNA/sRNA GTC ATA GCA ACA TCT GGC DNA/RNA 21 inactive ATT hybrid 5.2-RNA-5'-20 TC ATA GCA ACA TCT GGC dsRNA 20 active ATT 5.2-RNA-5'-19 C ATA GCA ACA TCT GGC dsRNA 19 less active ATT 5.2-RNA-5'-18 ATA GCA ACA TCT GGC ATT dsRNA 18 inactive 5.2-RNA-M1 GTC ATA GCA ACA TCT GGC dsRNA 21 active ATa 5.2-RNA-M2 GTC ATA GCA ACA TCT GGC dsRNA 21 active Aaa 5.2-RNA-M3 GTC ATA GCA AgA TCT GGC dsRNA 21 inactive ATT 5.2-RNA-M4 GTC ATA GCA tgt TCT GGC dsRNA 21 less active ATT 5.2-RNA-M5 GTC Aat GCA ACA TCT GGC dsRNA 21 active ATT 38 WO 2013/039990 PCT/US2012/054789 5.2-RNA-M6 GTC ATA GCA ACA TCT ccC dsRNA 21 active ATT 5.2-RNA-3'ddC GTC ATA GCA ACA TCT GGC dsRNA 22 inactive ATT-3'ddC 5.2-RNA-3'IdT GTC ATA GCA ACA TCT GGC dsRNA 22 inactive ATT-3'IdT 3' Deletion Analysis AS83-DNA-25-wt CTC TTT GTT TTT CTT CTG ssDNA 25 active CCA ATT T AS83-DNA-24- CTC TTT GTT TTT CTT CTG ssDNA 24 active 3'D CCA ATT AS83-DNA-23- CTC TTT GTT TTT CTT CTG ssDNA 23 active 3'D CCA AT AS83-DNA-22- CTC TTT GTT TTT CTT CTG ssDNA 22 active 3'D CCA A AS83-DNA-21- CTC TTT GTT TTT CTT CTG ssDNA 21 active 3'D CCA AS83-DNA-20- CTC TTT GTT TTT CTT CTG CC ssDNA 20 active 3'D AS83-DNA-19- CTC TTT GTT TTT CTT CTG C ssDNA 19 inactive 3'D AS83-DNA-18- CTC TTT GTT TTT CTT CTG ssDNA 18 inactive 3'D AS83-DNA-17- CTC TTT GTT TTT CTT CT ssDNA 17 inactive 3'D 5' Deletion Analysis AS83-DNA-24- TCT TTG TTT TTC TTC TGC ssDNA 24 active 5'D CAA TTT AS83-DNA-23- CTT TGT TTT TCT TCT GCC ssDNA 23 active 5'D AAT TT AS83-DNA-22- TTT GTT TTT CTT CTG CCA ssDNA 22 active 5'D ATT T AS83-DNA-21- TTG TTT TTC TTC TGC CAA ssDNA 21 active 5'D TTT AS83-DNA-20- TTG TTT TTC TTC TGC CAA ssDNA 20 active 5'D TT AS83-DNA-19- TTG TTT TTC TTC TGC CAA T ssDNA 19 less active 5'D AS83-DNA-18- TTG TTT TTC TTC TGC CAA ssDNA 18 inactive 5'D AS83-DNA-17- TTG TTT TTC TTC TGC CA ssDNA 17 inactive 5'D Mutational Analysis 39 WO 2013/039990 PCT/US2012/054789 AS83-DNA-5'M1 gTC TTT GTT TTT CTT CTG ssDNA 25 less active CCA ATT T AS83-DNA-5'M2 gaC TTT GTT TTT CTT CTG ssDNA 25 less active CCA ATT T AS83-DNA-M3 CTC TTT GTT TTT gTT CTG ssDNA 25 less active CCA ATT T AS83-DNA-M4 CTC TTT GTT TTa gaT CTG ssDNA 25 less active CCA ATT T AS83-DNA-M5 CTC TTT caa TTT CTT CTG ssDNA 25 less active CCA ATT T AS83-DNA-M6 CTC TTT GTT TTT CTT Cac ssDNA 25 less active gCA ATT T AS83-DNA-3'M1 CTC TTT GTT TTT CTT CTG ssDNA 25 less active CCA ATT a AS83-DNA-3'M2 CTC TTT GTT TTT CTT CTG ssDNA 25 inactive CCA ATa a AS83-DNA-3'ddC CTC TTT GTT TTT CTT CTG ssDNA 26 inactive CCA ATT T-3'ddC AS83-DNA- CTC TTT GTT TTT CTT CTG ssDNA 26 inactive 3'InvdT CCA ATT T-3'InvdT Example 4. Identification of effective trigger polynucleotides One non-limiting example of a method for selecting a polynucleotide for use in a composition for topical application to the surface of a parent plant involves the mapping of efficacious oligonucleotide or polynucleotide sequences (or segments of sequences) using a whole-gene (or full-length reference sequence) tiling array approach. The available full-length reference sequence is divided into "tiling sequences" or segments of 25 contiguous nucleotides along the entire length of the available sequence. For convenience, an Excel template was developed to allow convenient generation of sense and anti-sense tiling sequences for any given full-length reference sequence, providing as output a list of sense and anti-sense sequences for submission to oligonucleotide synthesis providers such as IDT (Integrated DNA Technologies, Coralville, IA). Oligonucleotides corresponding to each 25-mer tiling sequence (in sense, anti sense, or both sense and anti-sense orientation) are synthesized for efficacy screening. Oligonucleotides are screened in sets. It is clear to one skilled in the art that the tiling sequences can be of sizes other than 25 nucleotides (such as about 18, 19, 20, 21, 22, 23, or 24 nucleotides, or larger than 25 nucleotides), that these tiling sequences can be designed to be contiguous segments with no overlap or to overlap adjacent segments, and that such tiling sequences can be 40 WO 2013/039990 PCT/US2012/054789 grouped into sets of any size. For example, sets of five individual oligonucleotides are pooled into a single polynucleotide composition using 20 mM phosphate buffer and 2 percent w/v ammonium sulfate and 1 percent Silwet L-77, and topically applied to plants at a rate known to be efficacious for the plant species of interest (e. g., 4 nanomoles per plant). Those oligonucleotide sets showing better efficacy are then re-screened by testing the individual component oligonucleotides for efficacy. A specific example of selecting a polynucleotide for use in a composition for topical application to the surface of a parent plant follows. An EPSPS promoter 1302 nucleotide sequence was identified from genomic sequence of Palmer amaranth (Amaranthus palmeri) as having the sequence SEQ ID NO: 3543. A 1152 nucleotide segment of the 1302 nucleotides EPSPS promoter sequence was used in this example. The 1152-nt EPSPS promoter sequence was "tiled" (i. e., the full-length sequence covered by overlapping shorter sequences) by 25-mer anti-sense (AS) and sense (S) ssDNAs. A total of 96 25-mer ssDNA oligonucleotides were designed and grouped into 16 sets of 6 ssDNA oligonucleotides each (each set covering 150 contiguous nucleotides of the promoter sequence). The oligonucleotides were synthesized by IDT in 96-well plate format. Oligonucleotide sequences are provided in Table 3 (SEQ ID NO: 3588-3779). The oligonucleotides in a given set consisted of six contiguous sequences (in terms of their position within the 1152-nt full length sequence) where each oligonucleotide did not overlap the adjacent oligonucleotide(s). Table 3. Polynucleotides for targeting Amaranthus palmeri EPSPS promoter Name Antisense Sequence SEQ Name Sense Sequence SEQ ID ID NO: NO: ASI cgaatcaaaggaaaaagttatccaa 3588 S_1 ttggataactttttcctttgattcg 3684 AS2 aataatccgattcgaatcaaaggaa 3589 S_3 gaatcggattatttttaatacagta 3686 AS3 tactgtattaaaaataatccgattc 3590 S_5 attatgaactgatttaatgaaagtg 3688 AS4 atcagttcataatactgtattaaaa 3591 S_7 ggaggaagtttcaatttttaaagtt 3690 AS5 cactttcattaaatcagttcataat 3592 S_9 tgtaggtgtaatgttttctcatttt 3692 AS6 tgaaacttcctccactttcattaaa 3593 S_11 tggatatgaaagtggaggaagtttc 3694 AS7 aactttaaaaattgaaacttcctcc 3594 S_2 ttcctttgattcgaatcggattatt 3685 AS8 cattacacctacaactttaaaaatt 3595 S_4 ttttaatacagtattatgaactgat 3687 AS9 aaaatgagaaaacattacacctaca 3596 S_6 tttaatgaaagtggaggaagtttca 3689 AS1O actttcatatccaaaatgagaaaac 3597 S_8 aatttttaaagttgtaggtgtaatg 3691 AS11 gaaacttcctccactttcatatcca 3598 S_10 gttttctcattttggatatgaaagt 3693 AS12 tgattcgaaattgaaacttcctcca 3599 S_12 tggaggaagtttcaatttcgaatca 3695 41 WO 2013/039990 PCT/US2012/054789 AS13 aactggcaaacatgattcgaaattg 3600 S_13 caatttcgaatcatgtttgccagtt 3696 AS14 attcattgaatcaactggcaaacat 3601 S_15 tgattcaatgaatgctcttggaaat 3698 AS15 atttccaagagcattcattgaatca 3602 S_17 tgaccaagagttcaaggcttcttgt 3700 AS16 gaactcttggtcatttccaagagca 3603 S_19 ttataaaacatttcaattttgatct 3702 AS17 acaagaagccttgaactcttggtca 3604 S_21 taagaatgaactatttagaacttaa 3704 AS18 aaatgttttataacaagaagccttg 3605 S_23 aagtaattaaattattagttataac 3706 AS19 agatcaaaattgaaatgttttataa 3606 S_14 atgtttgccagttgattcaatgaat 3697 AS20 tagttcattcttagatcaaaattga 3607 S_16 tgctcttggaaatgaccaagagttc 3699 AS21 ttaagttctaaatagttcattctta 3608 S_18 caaggcttcttgttataaaacattt 3701 AS22 aatttaattactttaagttctaaat 3609 S_20 tcaattttgatctaagaatgaacta 3703 AS23 gttataactaataatttaattactt 3610 S_22 atttagaacttaaagtaattaaatt 3705 AS24 atttttttataagttataactaata 3611 S_24 tattagttataacttataaaaaaat 3707 AS25 ggttaaaattgaatttttttataag 3612 S_25 cttataaaaaaattcaattttaacc 3708 AS26 ttataaatttaaggttaaaattgaa 3613 S_27 cttaaatttataaattatgacctta 3710 AS27 taaggtcataatttataaatttaag 3614 S_29 aaaaagatcaagtattgaacgcata 3712 AS28 acttgatctttttaaggtcataatt 3615 S_31 atttagaaaaattataattcggctt 3714 AS29 tatgcgttcaatacttgatcttttt 3616 S_33 tatcagtctcatattgagacggtct 3716 AS30 aatttttctaaatatgcgttcaata 3617 S 35 Tcgtccaagacaagttgtatcattt 3718 AS31 aagccgaattataatttttctaaat 3618 S_26 ttcaattttaaccttaaatttataa 3709 AS32 tatgagactgataagccgaattata 3619 S_28 aattatgaccttaaaaagatcaagt 3711 AS33 agaccgtctcaatatgagactgata 3620 S_30 tattgaacgcatatttagaaaaatt 3713 AS34 Ttgtcttggacgagaccgtctcaat 3621 S 32 tataattcggcttatcagtctcata 3715 AS35 aaatgatacaacttgtcttggacga 3622 S 34 attgagacggtctcgtccaagacaA 3717 AS36 atttgattatataaatgatacaact 3623 S_36 Agttgtatcatttatataatcaaat 3719 AS37 actcataattatatttgattatata 3624 S_37 Tatataatcaaatataattatgagt 3720 AS38 ctacatgaatacactcataattata 3625 S_39 Tgtattcatgtaggtttcaacttta 3722 AS39 taaagttgaaacctacatgaataca 3626 S_41 Aaagcctaggtgaaagatatgttgt 3724 AS40 tcacctaggctttaaagttgaaacc 3627 S_43 Tagcatctttgtgaaagtcagccta 3726 AS41 acaacatatctttcacctaggcttt 3628 S_45 Ataacttggttctaaaattttgaag 3728 AS42 cacaaagatgctacaacatatcttt 3629 S_47 Gcataaccatatagtccctcgaatt 3730 AS43 taggctgactttcacaaagatgcta 3630 S_38 Tataattatgagtgtattcatgtag 3721 AS44 agaaccaagttataggctgactttc 3631 S_40 Ggtttcaactttaaagcctaggtga 3723 AS45 cttcaaaattttagaaccaagttat 3632 S_42 Aaagatatgttgtagcatctttgtg 3725 AS46 tatatggttatgcttcaaaatttta 3633 S_44 Gaaagtcagcctataacttggttct 3727 AS47 aattcgagggactatatggttatgc 3634 S_46 Taaaattttgaagcataaccatata 3729 AS48 acaacttgaatgaattcgagggact 3635 S_48 Agtccctcgaattcattcaagttgt 3731 AS49 aaagtaaattggacaacttgaatga 3636 S_49 Tcattcaagttgtccaatttacttt 3732 AS50 ggcaagtataaaaaagtaaattgga 3637 S_51 Ttttatacttgccgagacaacattt 3734 AS51 aaatgttgtctcggcaagtataaaa 3638 S_53 Ttaaacccttaatatttctaattaa 3736 AS52 attaagggtttaaaatgttgtctcg 3639 S_55 Atcttaattaaaaattatgaaaatt 3738 AS53 ttaattagaaatattaagggtttaa 3640 S_57 Ttgatattaataatctttgtattga 3740 AS54 ttttaattaagattaattagaaata 3641 S_59 Aaacgaatttaacaagatctcacat 3742 AS55 aattttcataatttttaattaagat 3642 S 50 Tccaatttacttttttatacttgcc 3733 AS56 ttattaatatcaaattttcataatt 3643 S_52 Cgagacaacattttaaacccttaat 3735 AS57 tcaatacaaagattattaatatcaa 3644 S_54 Tatttctaattaatcttaattaaaa 3737 AS58 gttaaattcgtttcaatacaaagat 3645 S_56 Aattatgaaaatttgatattaataa 3739 42 WO 2013/039990 PCT/US2012/054789 AS59 atgtgagatcttgttaaattcgttt 3646 S_58 Atctttgtattgaaacgaatttaac 3741 AS60 taaaacatagtcatgtgagatcttg 3647 S_60 Caagatctcacatgactatgtttta 3743 AS61 taatctataagttaaaacatagtca 3648 S_61 Tgactatgttttaacttatagatta 3744 AS62 ttgtattttttttaatctataagtt 3649 S_63 Aaaaaaaatacaaattaagagtgat 3746 AS63 atcactcttaatttgtatttttttt 3650 S_65 Taagtgaatagtgccccaaaacaaa 3748 AS64 cactattcacttatcactcttaatt 3651 S_67 Atgggacaacttagatgaattggag 3750 AS65 tttgttttggggcactattcactta 3652 S_69 Ggtaatattaggtagcaagtgatct 3752 AS66 taagttgtcccatttgttttggggc 3653 S_71 Tagcaagtgatcactttaacatcaa 3754 AS67 ctccaattcatctaagttgtcccat 3654 S_62 Aacttatagattaaaaaaaatacaa 3745 AS68 acctaatattacctccaattcatct 3655 S_64 Aattaagagtgataagtgaatagtg 3747 AS69 agatcacttgctacctaatattacc 3656 S_66 Gccccaaaacaaatgggacaactta 3749 AS70 tgatcacttgctagatcacttgcta 3657 S_68 Agatgaattggaggtaatattaggt 3751 AS71 ttgatgttaaagtgatcacttgcta 3658 S_70 Tagcaagtgatctagcaagtgatca 3753 AS72 aagtgatcaattttgatgttaaagt 3659 S_72 Actttaacatcaaaattgatcactt 3755 AS73 atttgaacctataagtgatcaattt 3660 S_73 Aaattgatcacttataggttcaaat 3756 AS74 gtaaaagtttcaatttgaacctata 3661 S_75 Ttgaaacttttactttaattgatat 3758 AS75 atatcaattaaagtaaaagtttcaa 3662 S_77 Tgtttaaatactactttaaattgaa 3760 AS76 tagtatttaaacatatcaattaaag 3663 S_79 Aattgatatttttaaggtcaaaatt 3762 AS77 ttcaatttaaagtagtatttaaaca 3664 S_81 Tgaaacctttaagattataattgaa 3764 AS78 aaaaatatcaatttcaatttaaagt 3665 S 83 Aaattggcagaagaaaaacaaagag 3766 AS79 aattttgaccttaaaaatatcaatt 3666 S_74 Tataggttcaaattgaaacttttac 3757 AS80 cttaaaggtttcaattttgacctta 3667 S_76 Ctttaattgatatgtttaaatacta 3759 AS81 ttcaattataatcttaaaggtttca 3668 S_78 Actttaaattgaaattgatattttt 3761 AS82 cttctgccaattttcaattataatc 3669 S_80 Taaggtcaaaattgaaacctttaag 3763 AS83 ctctttgtttttcttctgccaattt 3670 S_82 Gattataattgaaaattggcagaag 3765 AS84 cttatattctttctctttgtttttc 3671 S_84 Gaaaaacaaagagaaagaatataag 3767 AS85 caatttgcgtgtcttatattctttc 3672 S_85 Gaaagaatataagacacgcaaattg 3768 AS86 agtagatcggtacaatttgcgtgtc 3673 S_87 Gtaccgatctactcttatttcaatt 3770 AS87 aattgaaataagagtagatcggtac 3674 S_89 Tttgagacggtctcgcccaagacta 3772 AS88 agaccgtctcaaaattgaaataaga 3675 S_91 Agatgttcggtcatcctacaccaac 3774 AS89 tagtcttgggcgagaccgtctcaaa 3676 S_93 Ccccaaaaaattcaacaacaaagtc 3776 AS90 tgaccgaacatctagtcttgggcga 3677 S_95 Cttataatgattccctctaatctac 3778 AS91 gttggtgtaggatgaccgaacatct 3678 S_86 Gacacgcaaattgtaccgatctact 3769 AS92 gaattttttggggttggtgtaggat 3679 S_88 Tcttatttcaattttgagacggtct 3771 AS93 gactttgttgttgaattttttgggg 3680 S_90 Tcgcccaagactagatgttcggtca 3773 AS94 gaatcattataagactttgttgttg 3681 S_92 Atcctacaccaaccccaaaaaattc 3775 AS95 gtagattagagggaatcattataag 3682 S_94 Caacaacaaagtcttataatgattc 3777 AS96 gtgtagactgtagtagattagaggg 3683 S_96 Ccctctaatctactacagtctacac 3779 Oligonucleotide sets assigned an even number n contain oligonucleotides with a sequence shifted by 12 or 13 nucleotides (nt) relative to the 3'end of the oligonucleotides in sets assigned a number equal to (n - 1). For example, the oligonucleotide sequences in set number 2 have a sequence shifted by 12 or 13 nt relative to the 3' end of the oligonucleotides in set number 1. 43 WO 2013/039990 PCT/US2012/054789 The ssDNA oligonucleotides were formulated as 100 micromolar (per oligonucleotide) mixtures (each consisting of a set of 6 oligonucleotides) in 20 millimolar phosphate buffer (pH 7.0), 2% ammonium sulfate, 1% Silwet@ L-77, and were hand applied by pipetting to the surface of four fully expanded source leaves of glyphosate-resistant Palmer amaranth (Amaranthus palmeri R-22) plants. Each leaf received 10 microliters of 100 micromolar ssDNA solution (a total of 1 nanomole per oligonucleotide per leaf for a total 4 nanomole per oligonucleotide per plant). Silwet-containing buffer without oligonucleotides was applied as a negative control. A composition of four EPSPS short dsRNA1, 3, 4 and 5 (see Example 6) were applied at 4 nm each oligonucleotide per plant as positive control. The Palmer plants were then sprayed with 2X WeatherMax (1.5 lb/ac) at either 2 or 3-day after oligos treatment. The first round of efficacy testing showed that sets 8 and 13 gave better herbicidal control of Palmer amaranth (for both sense and anti-sense strands). A second round of efficacy testing used the 12 individual oligonucleotides in sets 8 and 13 and showed that five individual ssDNA oligonucleotides numbered 44, 48, 79, 81, and 83 gave better herbicidal control of Palmer amaranth than the other seven ssDNA oligonucleotides. These five ssDNA oligonucleotides were individually tested at 16 nmol/plant followed by 2X WMax on Palmer R-22 plants. The treated Palmer amaranth plants were observed ten days after treatment and showed that ssDNA oligonucleotides numbers 79 (SEQ ID NO: 3666), 81(SEQ ID NO: 3668), and 83(SEQ ID NO: 3670) gave 95, 98 and 99 percent control respectively when applied in combination with dsRNA5 (EPSPS) and dsRNATIF1 (SEQ ID NO: 3780). Further experimental testing of the AS83 trigger that targets the EPSPS promoter in Palmer R-22 was conducted in which the AS83 trigger was used to make ssDNA, dsRNA (SEQ ID NO:3789) and dsDNA. These AS83 molecules were tested as described in Exampe 3 and the results shown in Table 4 determined that all of the molecular forms of AS83 were active in making the Palmer R-22 plant sensitive to glyphosate. Table 4. EPSPS promoter AS83 trigger molecules Oligo Name Sequence (AS/bottom strand) Type Size Activity AS83-DNA-wt- CTC TTT GTT TTT CTT CTG ssDNA 25 active CCA ATT T 44 WO 2013/039990 PCT/US2012/054789 AS83-RNA-wt- CUC UUU GUU UUU CUU CUG dsRNA 25 active CCA AUU U AS83-DNA-blunt CTC TTT GTT TTT CTT CTG dsDNA 25 active CCA ATT T Example 5 Tiling of tigger oligonucleotides was conducted on a Palmer amaranth EPSPS coding region using a similar testing protocol as described in Example 3. In this test, approximately 700 base pairs of coding region were used to select 46 individual antisense ssDNA oligonucleotides each 25 nucleotides long. These were applied to Palmer amaranth plants (R-22) at l2nmole per oligonucleotide per plant, followed by 2X WeatherMax 2 days after oligonucleotide treatment later. . The plants were scored for glyphosate effect on growth. As shown in Figure 1 , there were two regions identified in the coding sequence where many of the trigger molecules were able to provide a glyphosate sensitive phenotype to the treated plants, these are identified by the boxes in Figure 1. The 5' region (Region 1, SEQ ID NO:3787) is approximately 150 nucleotides including and between antisense oligo 34 (SEQ ID NO: 3781) and 57 (SEQ ID NO: 3782) and the 3' region (Region 2, SEQ ID NO:3788) is approximately 100 nucleotides including and between antisense oligo 32 (SEQ ID NO:3783) and oligo 36 (SEQ ID NO:3784). The triggers plus glyphosate provided 30-70 percent and 25-45 percent control in the 5' region and in the 3' region, respectively. Additional trigger polynucleotides in these regions include oligo 81 (SEQ ID NO: 3785) and oligo 95 (SEQ ID NO: 3786). It is contemplated that additional trigger molecules can be identified in these regions and combinations of triggers would be useful to provide a high level of glyphosate sensitivity. Example 6. Effects on transgenic herbicide tolerant plants This example demonstrates that the topical application of a polynucleotide trigger molecule can be used to make transgenic herbicide tolerant crops sensitive to the herbicide for which they were engineered to be tolerant. In this example, a gene coding sequence for Agrobacterium tumefaciens CP4 EPSPS (SEQ ID NO: 1) was targeted with two dsRNA trigger molecules referred to as CP4-12 (82-462 of SEQ ID NO:1) a 381 polynucleotide, and CP4-34 (594-1043 of SEQ ID NO: 1) a 450 polynucleotide. Corn and cotton plants that were transformed 45 WO 2013/039990 PCT/US2012/054789 with the CP4 EPSPS gene and are resistant to glyphosate were planted in pots in a greenhouse along with negative isolines for each and grown to the first true leaf emergence stage then treated with a trigger solution containing 0.5% Silwet L77, 2% ammonium sulfate, 20 mM Na Phoshpate (pH 6.8) at different rates of trigger amount, 0 picomoles (pmol), 210 pmol, 630 pmol and 1890 pmol. For each replication (8-10 plants), two fully expanded cotyledons were treated by pipette with 50 microliters of trigger solution each, then sprayed two-three days later with 1.5 a.e.lb/acre) of RoundUpTM Ultra (glyphosate, Monsanto, St Louis, MO). The cotton and corn plants were scored for stunting and injury 7-16 days after spray treatment. Figures 2 and 3 show the corn and cotton plant results, respectively. The corn plants in Figure 2 shows the number of treated plants that showed glyphosate injury after treatment with the trigger polynucleotides and glyphosate, injury was observed as dead or damaged terminal leaves 2-4 days after RoundUp treatment, and stunting was evident 7-14 days after RoundUp treatment. The nontransgenic control is labeled "Minus CP4", these plant were killed by the RoundUp treatment. Figure 3 shows the results of glyphosate tolerant cotton plants treated with the trigger polynucleotides and glyphosate, symptoms observed on the cotton plants were severe stunting and death of the apical meristem. These results demonstrate that topical treatment with a trigger polynucleotide can be used to effect a herbicide tolerant trait in a transgenic herbicide tolerant crop plant. Example 7. Enhancement with the addition of non-EPSPS herbicides This example demonstrates that the addition of herbicides with a mode of action different than glyphosate that enhance the effect of the treatment comprising glyphosate , an EPSPS trigger polynucleotides, and an essential gene (transcription initiation factor, TIF) trigger polynucleotide. Glyphosate is applied as a Roundup WeatherMAX® formulation (RU Wmax, Monsanto, St Louis, MO) at 2X (1.5 pounds acid equivalent/acre), 4X and 8X in a field test plot infested with glyphosate resistant A. palmeri. Clarity@ (Diglycolamine salt, BASF) is a dicamba formulation applied at 0.25 pounds/acre (lb/ac) is equal to half of the recommended use rate for broadleaf weed control. The polynucleotides are all dsRNA, 4001 is mixture of the following four A. palmeri EPSPS dsRNA trigger polynucleotides: dsRNA1: sense strand sequence CUACCAUCAACAAUGGUGUCC (1479-1499 of SEQ ID NO: 10) and complementary anti-sense strand, and dsRNA3: sense strand GUCGACAACUUGCUGUAUAGU 46 WO 2013/039990 PCT/US2012/054789 (4241-4261 of SEQ ID NO: 10) and complementary anti-sense strand, and dsRNA4: sense strand GGUCACCUGGACAGAGAAUAG(9919-9939 of SEQ ID NO: 10) and complementary anti-sense strand, and dsRNA5: sense strand AAUGCCAGAUGUUGCUAUGAC (10015-10035 of SEQ ID NO: 10) and complementary anti-sense strand and one A. palmeri TIF dsRNA trigger polynucleotide (dsRNATIF1: sense strand GCACAAAUGUAAAUAAACCGUCUCC (SEQ ID NO: 3780) and complementary anti-sense strand), 4002 is mixture of one EPSPS dsRNA trigger polynucleotide (dsRNA5) and one A. palmeri TIF dsRNA trigger polynucleotide (dsRNATIF 1). The composition of the herbicides and polynucleotides also contain one percent Silwet L77. The treatments of the field plots containing glyphosate resistant A. palmeri plants (mostly 4-6 inches tall) with compositions shown in Table 6 with 4 replications per treatment at a spray volume of 10 gallons per acre, the total polynucleotide concentration was in the composition was approximately 160nmol. The treated glyphosate resistant A. palmeri were scored for percent injury between 10-14 days post treatment. The results show that glyphosate (RU Wmax) was not effective in controlling this population of resistant A. palmeri even at 8X the recommended field rates, 52.5 percent. The addition of the 4001 and 4002 polynucleotides substantially increased the observed glyphosate percent injury, 83.75 and 72.5 percent respectively. The treatments that also included 0.25 lb/ac Clarity (dicamba) increased the injury rate to 95.75 percent when included in the composition with the 4001 trigger polynucleotides and to 93.25 percent when included in the composition with the 4002 trigger polynucleotides. The RU Wmax and Clarity alone showed a 83.75 percent injury rate on the glyphosate resistant A. palmeri. Table 5. Addition of Dicamba to glyphosate and EPSPS and essential gene trigger polynucleotides enhances injury rates to glyphosate resistant A. palmeri. Treatment Percent injury std err Mean RU Wmax 2X 28.75 12.045 RU Wmax 4X 30 4.291 RU Wmax 8X 52.5 11.219 47 WO 2013/039990 PCT/US2012/054789 2X RU Wmax + 4001 83.75 3.1 2X RU Wmax + 4001 + 0.25 lb 95.75 4.095 Clarity 2X RU Wmax + 4002 72.5 3.067 2X RU Wmax + 4002 + 0.25 lb 93.25 3.513 Clarity 2X RU Wmax + 0.25 lb Clarity 83.75 6.221 A greenhouse test was conducted to determine the effect of a composition containing 2,4-D herbicide, an EPSPS dsRNA, an essential gene dsRNA and a glyphosate herbicide. The polynucleotides used in the test was 4002 which is a mixture of 1 EPSPS dsRNA trigger polynucleotide (dsRNA5) and 1 A. palmeri TIF dsRNA trigger polynucleotide (dsRNATIF1), at a concentration of 80nm applied with a 9501E nozzle at 93 L/ha (liters/hectare). Roundup WeatherMax@ was the glyphosate herbicide and applied at the 2X rate. The 2,4-D herbicide is 2,4D amine (dimethylamine salt) at a concentration of 3.8 lb/gal and tested at 2 rates, 0.0625 pounds/acre (lb/ac) and 0.125 lb/ac. The composition of the herbicides and polynucleotides also contain one percent Silwet L77. A. palmeri (R-22) were treated with the compositions listed in Table 6 when they were between 4-8 centimeters tall and had 6-12 leaves, there were 6 replications in the experiment. The effect of the composition was measured as percent control relative to an untreated control 14 days after treatment. Table 6 shows that the composition containing the polynucleotides and glyphosate had enhanced herbicidal activity when 2,4-D was included in the composition as demonstrated by the reduced rate needed to provide the same level of percent control as twice the amount. Table 6. Addition of 2,4-D to glyphosate and trigger polynucleotides % Control Treatment Description (mean) Roundup WeatherMAX (1.5/A) 51.7 2,4-D (0.06251b/A) 60 2,4-D (0. 1251b/A) 80.8 RU Wmax (1.51b/A) + 2,4-D (0.06251b/A) 57.5 48 WO 2013/039990 PCT/US2012/054789 RU Wmax (1.51b/A) + 2,4-D (0.1251b/A) 77.5 4002 + RU Wmax (1.51b/A) + 2,4-D (0.06251b/A) 80.8 4002 + RU Wmax (1.51b/A) + 2,4-D (0.1251b/A) 88.3 Example 8. A method to control weeds in a field. A method to control weeds in a field comprises the use of trigger polynucleotides that can modulate the expression of an EPSPS gene in one or more target weed plant species. Example 5 showed that a weed control composition comprising multiple herbicides and multiple polynucleotides can be used in a field environment to control A. palmeri plant growth. An analysis of EPSPS gene sequences from 20 plant species provided a collection of 21-mer polynucleotides (SEQ ID NO:3223-3542) that can be used in compositions to affect the growth or develop or sensitivity to glyphosate herbicide to control multiple weed species in a field. A composition containing 1 or 2 or 3 or 4 or more of the polynucleotides of SEQ ID NO:3223 3542 would enable broad activity of the composition against the multiple weed species or variant populations that occur in a field environment. The method includes creating an agricultural chemical composition that comprises components that include at least one polynucleotide of SEQ ID NO:3223-3542 or any other effective gene expression modulating polynucleotide essentially identical or essentially complementary to SEQ ID NO: 1-120 or fragment thereof, a transfer agent that mobilizes the polynucleotide into a plant cell and a glyphosate containing herbicide and optionally a polynucleotide that modulates the expression of an essential gene and optionally a herbicide that has a different mode of action relative to glyphosate. The polynucleotide of the composition includes a dsRNA, ssDNA or dsDNA or a combination thereof. A composition containing a polynucleotide can have a use rate of about 1 to 30 grams or more per acre depending on the size of the polynucleotide and the number of polynucleotides in the composition. The composition may include one or more additional herbicides as needed to provide effective multi-species weed control. For example, a composition comprising an EPSPS gene trigger oligonucleotide, the composition further including a co-herbicide but not limited to acetochlor, acifluorfen, acifluorfen-sodium, aclonifen, acrolein, alachlor, alloxydim, allyl alcohol, ametryn, amicarbazone, amidosulfuron, aminopyralid, amitrole, ammonium sulfamate, anilofos, asulam, atraton, atrazine, azimsulfuron, BCPC, beflubutamid, benazolin, benfluralin, 49 WO 2013/039990 PCT/US2012/054789 benfuresate, bensulfuron, bensulfuron-methyl, bensulide, bentazone, benzfendizone, benzobicyclon, benzofenap, bifenox, bilanafos, bispyribac, bispyribac- sodium, borax, bromacil, bromobutide, bromoxynil, butachlor, butafenacil, butamifos, butralin, butroxydim, butylate, cacodylic acid, calcium chlorate, cafenstrole, carbetamide, carfentrazone, carfentrazone-ethyl, CDEA, CEPC, chlorflurenol, chlorflurenol-methyl, chloridazon, chlorimuron, chlorimuron-ethyl, chloroacetic acid, chlorotoluron, chlorpropham, chlorsulfuron, chlorthal, chlorthal-dimethyl, cinidon-ethyl, cinmethylin, cinosulfuron, cisanilide, clethodim, clodinafop, clodinafop-propargyl, clomazone, clomeprop, clopyralid, cloransulam, cloransulam-methyl, CMA, 4-CPB, CPMF, 4-CPP, CPPC, cresol, cumyluron, cyanamide, cyanazine, cycloate, cyclosulfamuron, cycloxydim, cyhalofop, cyhalofop-butyl, 2,4-D, 3,4-DA, daimuron, dalapon, dazomet, 2,4-DB, 3,4-DB, 2,4-DEB, desmedipham, dicamba, dichlobenil, ortho-dichlorobenzene, para-dichlorobenzene, dichlorprop, dichlorprop-P, diclofop, diclofop-methyl, diclosulam, difenzoquat, difenzoquat metilsulfate, diflufenican, diflufenzopyr, dimefuron, dimepiperate, dimethachlor, dimethametryn, dimethenamid, dimethenamid-P, dimethipin, dimethylarsinic acid, dinitramine, dinoterb, diphenamid, diquat, diquat dibromide, dithiopyr, diuron, DNOC, 3,4-DP, DSMA, EBEP, endothal, EPTC, esprocarb, ethalfluralin, ethametsulfuron, ethametsulfuron-methyl, ethofumesate, ethoxyfen, ethoxysulfuron, etobenzanid, fenoxaprop-P, fenoxaprop-P-ethyl, fentrazamide, ferrous sulfate, flamprop-M, flazasulfuron, florasulam, fluazifop, fluazifop butyl, fluazifop-P, fluazifop-P-butyl, flucarbazone, flucarbazone-sodium, flucetosulfuron, fluchloralin, flufenacet, flufenpyr, flufenpyr-ethyl, flumetsulam, flumiclorac, flumiclorac pentyl, flumioxazin, fluometuron, fluoroglycofen, fluoroglycofen-ethyl, flupropanate, flupyrsulfuron, flupyrsulfuron-methyl- sodium, flurenol, fluridone, fluorochloridone, fluoroxypyr, flurtamone, fluthiacet, fluthiacet-methyl, fomesafen, foramsulfuron, fosamine, glufosinate, glufosinate-ammonium, halosulfuron, halosulfuron-methyl, haloxyfop, haloxyfop-P, HC-252, hexazinone, imazamethabenz, imazamethabenz-methyl, imazamox, imazapic, imazapyr, imazaquin, imazethapyr, imazosulfuron, indanofan, iodomethane, iodosulfuron, iodosulfuron-methyl- sodium, ioxynil, isoproturon, isouron, isoxaben, isoxachlortole, isoxaflutole, karbutilate, lactofen, lenacil, linuron, MAA, MAMA, MCPA, MCPA-thioethyl, MCPB, mecoprop, mecoprop-P, mefenacet, mefluidide, mesosulfuron, mesosulfuron-methyl, mesotrione, metam, metamifop, metamitron, metazachlor, 50 WO 2013/039990 PCT/US2012/054789 methabenzthiazuron, methylarsonic acid, methyldymron, methyl isothiocyanate, metobenzuron, metolachlor, S-metolachlor, metosulam, metoxuron, metribuzin, metsulfuron, metsulfuron-methyl, MK-66, molinate, monolinuron, MSMA, naproanilide, napropamide, naptalam, neburon, nicosulfuron, nonanoic acid, norflurazon, oleic acid (fatty acids), orbencarb, orthosulfamuron, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone, oxyfluorfen, paraquat, paraquat dichloride, pebulate, pendimethalin, penoxsulam, pentachlorophenol, pentanochlor, pentoxazone, pethoxamid, petrolium oils, phenmedipham, phenmedipham-ethyl, picloram, picolinafen, pinoxaden, piperophos, potassium arsenite, potassium azide, pretilachlor, primisulfuron, primisulfuron-methyl, prodiamine, profluazol, profoxydim, prometon, prometryn, propachlor, propanil, propaquizafop, propazine, propham, propisochlor, propoxycarbazone, propoxycarbazone- sodium, propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraflufen, pyraflufen-ethyl, pyrazolynate, pyrazosulfuron, pyrazosulfuron-ethyl, pyrazoxyfen, pyribenzoxim, pyributicarb, pyridafol, pyridate, pyriftalid, pyriminobac, pyriminobac-methyl, pyrimisulfan, pyrithiobac, pyrithiobac- sodium, quinclorac, quinmerac, quinoclamine, quizalofop, quizalofop-P, rimsulfuron, sethoxydim, siduron, simazine, simetryn, SMA, sodium arsenite, sodium azide, sodium chlorate, sulcotrione, sulfentrazone, sulfometuron, sulfometuron-methyl, sulfosate, sulfosulfuron, sulfuric acid, tar oils, 2,3,6-TBA, TCA, TCA-sodium, tebuthiuron, tepraloxydim, terbacil, terbumeton, terbuthylazine, terbutryn, thenylchlor, thiazopyr, thifensulfuron, thifensulfuron-methyl, thiobencarb, tiocarbazil, topramezone, tralkoxydim, tri-allate, triasulfuron, triaziflam, tribenuron, tribenuron-methyl, tricamba, triclopyr, trietazine, trifloxysulfuron, trifloxysulfuron-sodium, trifluralin, triflusulfuron, triflusulfuron methyl, trihydroxytriazine, tritosulfuron, [3-[2-chloro-4-fluoro-5-(-methyl-6-trifluoromethyl 2,4-dioxo-,2,3,4-t- etrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy] acetic acid ethyl ester (CAS RN 353292-3-6), 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo)-H-,2,4-triazol--ylcarbonyl sulfamoyl]-5-methylthiophene-3-carboxylic acid (BAY636), BAY747 (CAS RN 33504-84-2), topramezone (CAS RN 2063-68-8), 4-hydroxy-3-[[2-[(2-methoxyethoxy)methyl]-6-(trifluoro methyl)-3-pyridi- nyl]carbonyl] -bicyclo[3.2.] oct-3-en-2-one (CAS RN 35200-68-5), and 4 hydroxy-3- [ [2- (3-methoxypropyl)-6- (difluoromethyl)-3 -pyridinyl] carbon- yl]-bicyclo[3.2.]oct-3 en-2-one. 51 WO 2013/039990 PCT/US2012/054789 A field of crop plants in need of weed plant control is treated by spray application of the composition. The composition can be provided as a tank mix, a sequential treatment of components (generally the polynucleotide followed by the herbicide), a simultaneous treatment or mixing of one or more of the components of the composition from separate containers. Treatment of the field can occur as often as needed to provide weed control and the components of the composition can be adjusted to target specific weed species or weed families. Example 9. Herbicidal Compositions comprising pesticidal agents A method of controlling weeds and plant pest and pathogens in a field of glyphosate tolerant crop plants is provided, wherein the method comprises applying a composition comprising an EPSPS trigger oligonucleotide, a glyphosate composition and an admixture of a pest control agent. For example, the admixture comprises insecticides, fungicides, nematocides, bactericides, acaricides, growth regulators, chemosterilants, semiochemicals, repellents, attractants, pheromones, feeding stimulants or other biologically active compounds or biological agents, such as, microorganisms. For example, the admixture comprises a fungicide compound for use on a glyphosate tolerant crop plant to prevent or control plant disease caused by a plant fungal pathogen, The fungicide compound of the admixture may be a systemic or contact fungicide or mixtures of each. More particularly the fungicide compound includes, but is not limited to members of the chemical groups strobilurins, triazoles, chloronitriles, carboxamides and mixtures thereof. The composition may additional have an admixture comprises an insecticidal compound or agent. The EPSPS trigger oligonucleotides and WeatherMAX® (WMAX) tank mixes with fungicides, insecticides or both are tested for use in soybean. Soybean rust is a significant problem disease in South America and serious concern in the U.S. Testing is conducted to develop a method for use of mixtures of the WMAX formulation and various commercially available fungicides for weed control and soy rust control. The field plots are planted with Roundup Ready@ soybeans. All plots receive a post plant application of the EPSPS trigger +WMAX about 3 weeks after planting. The mixtures of trigger +WMAX or trigger +WMAX + fungicide + insecticides are used to treat the plots at the RI stage of soybean development (first flowering) of treatment. Data is taken for percent weed control at 7 and 21 days after RI treatment, soybean safety (percent necrosis, chlorosis, growth rate): 5 days after treatment, 52 WO 2013/039990 PCT/US2012/054789 disease rating, and soybean yield (bushels/Acre). These mixtures and treatments are designed to provide simultaneous weed and pest control of soybean, such as fungal pest control, for example, soybean rust disease; and insect pest control, for example, aphids, armyworms, loopers, beetles, stinkbugs, and leaf hoppers. Agricultural chemicals are provided in containers suitable for safe storage, transportation and distribution, stability of the chemical compositions, mixing with solvents and instructions for use. A container of a mixture of a trigger oligonucleotide + glyphosate + fungicide compound, or a mixture of a trigger oligonucleotide + glyphosate compound and an insecticide compound, or a trigger oligonucleotide + a glyphosate compound and a fungicide compound and an insecticide compound (for example, lambda-cyhalothrin, Warrier®). The container may further provide instructions on the effective use of the mixture. Containers of the present invention can be of any material that is suitable for the storage of the chemical mixture. Containers of the present invention can be of any material that is suitable for the shipment of the chemical mixture. The material can be of cardboard, plastic, metal, or a composite of these materials. The container can have a volume of 0.5 liter, 1 liter, 2 liter, 3-5 liter, 5-10 liter, 10-20 liter, 20-50 liter or more depending upon the need. A tank mix of a trigger oligonucleotide + glyphosate compound and a fungicide compound is provided, methods of application to the crop to achieve an effective dose of each compound are known to those skilled in the art and can be refined and further developed depending on the crop, weather conditions, and application equipment used. Insecticides, fungicides, nematocides, bactericides, acaricides, growth regulators, chemosterilants, semiochemicals, repellents, attractants, pheromones, feeding stimulants or other biologically active compounds can be added to the trigger oligonucleotide to form a multi component pesticide giving an even broader spectrum of agricultural protection. Examples of such agricultural protectants with which compounds of this invention can be formulated are: insecticides such as abamectin, acephate, azinphos-methyl, bifenthrin, buprofezin, carbofuran, chlorfenapyr, chlorpyrifos, chlorpyrifos-methyl, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda cyhalothrin, deltamethrin, diafenthiuron, diazinon, diflubenzuron, dimethoate, esfenvalerate, fenoxycarb, fenpropathrin, fenvalerate, fipronil, flucythrinate, tau-fluvalinate, fonophos, imidacloprid, isofenphos, malathion, metaldehyde, methamidophos, methidathion, methomyl, methoprene, methoxychlor, methyl 7-chloro-2,5-dihydro-2-[[N-(methoxycarbonyl)-N-[4 (trifluoromethoxy)phenyl ]amino] carbonyl] indeno [1,2-e] [1,3,4] oxadiazine-4a(3H)-carboxylate 53 WO 2013/039990 PCT/US2012/054789 (DPX-JW062), monocrotophos, oxamyl, parathion, parathion-methyl, permethrin, phorate, phosalone, phosmet, phosphamidon, pirimicarb, profenofos, rotenone, sulprofos, tebufenozide, tefluthrin, terbufos, tetrachlorvinphos, thiodicarb, tralomethrin, trichlorfon and triflumuron; most preferably a glyphosate compound is formulated with a fungicide compound or combinations of fungicides, such as azoxystrobin, benomyl, blasticidin-S, Bordeaux mixture (tribasic copper sulfate), bromuconazole, captafol, captan, carbendazim, chloroneb, chlorothalonil, copper oxychloride, copper salts, cymoxanil, cyproconazole, cyprodinil (CGA 219417), diclomezine, dicloran, difenoconazole, dimethomorph, diniconazole, diniconazole-M, dodine, edifenphos, epoxiconazole (BAS 480F), famoxadone, fenarimol, fenbuconazole, fenpiclonil, fenpropidin, fenpropimorph, fluazinam, fluquinconazole, flusilazole, flutolanil, flutriafol, folpet, fosetyl aluminum, furalaxyl, hexaconazole, ipconazole, iprobenfos, iprodione, isoprothiolane, kasugamycin, kresoxim-methyl, mancozeb, maneb, mepronil, metalaxyl, metconazole, S-methyl 7-benzothiazolecarbothioate (CGA 245704), myclobutanil, neo-asozin (ferric methanearsonate), oxadixyl, penconazole, pencycuron, probenazole, prochloraz, propiconazole, pyrifenox, pyroquilon, quinoxyfen, spiroxamine (KWG4168), sulfur, tebuconazole, tetraconazole, thiabendazole, thiophanate-methyl, thiram, triadimefon, triadimenol, tricyclazole, trifloxystrobin, triticonazole, validamycin and vinclozolin; combinations of fungicides are common for example, cyproconazole and azoxystrobin, difenoconazole, and metalaxyl-M, fludioxonil and metalaxyl M, mancozeb and metalaxyl-M, copper hydroxide and metalaxyl-M, cyprodinil and fludioxonil, cyproconazole and propiconazole; commercially available fungicide formulations for control of Asian soybean rust disease include, but are not limited to Quadris@ (Syngenta Corp), Bravo@ (Syngenta Corp), Echo 720@ (Sipcam Agro Inc), Headline@ 2.09EC (BASF Corp), Tilt@ 3.6EC (Syngenta Corp), PropiMax T M 3.6EC (Dow AgroSciences), Bumper@ 41.8EC (MakhteshimAgan), Folicur@ 3.6F (Bayer CropScience), Laredo@ 25EC (Dow AgroSciences), Laredo T M 25EW (Dow AgroSciences), Stratego@ 2.08F (Bayer Corp), Domark TM 125SL (Sipcam Agro USA), and Pristine@38%WDG (BASF Corp) these can be combined with glyphosate compositions as described in the present invention to provide enhanced protection from soybean rust disease; nematocides such as aldoxycarb and fenamiphos; bactericides such as streptomycin; acaricides such as amitraz, chinomethionat, chlorobenzilate, cyhexatin, dicofol, dienochlor, etoxazole, fenazaquin, fenbutatin oxide, fenpropathrin, fenpyroximate, hexythiazox, propargite, pyridaben and tebufenpyrad; and biological agents such as Bacillus thuringiensis, 54 WO 2013/039990 PCT/US2012/054789 Bacillus thuringiensis delta endotoxin, baculovirus, and entomopathogenic bacteria, virus and fungi. Table 1. EPSPS gene polynucleotide sequences SEQ SPECIES TYPE LENGTH SEQ ID NO 1 Agrobacteri cDNA 1362 CACGGTGCAAGCAGCCGGCCCGCAACCGCCCGCAAATCC um TCTGGCCTTTCCGGAACCGTCCGCATTCCCGGCGACAAG tumefaciens TCGATCTCCCACCGGTCCTTCATGTTCGGCGGTCTCGCG AGCGGTGAAACGCGCATCACCGGCCTTCTGGAAGGCGAG GACGTCATCAATACGGGCAAGGCCATGCAGGCCATGGGC GCCAGGATCCGTAAGGAAGGCGACACCTGGATCATCGAT GGCGTCGGCAATGGCGGCCTCCTGGCGCCTGAGGCGCCG CTCGATTTCGGCAATGCCGCCACGGGCTGCCGCCTGACC ATGGGCCTCGTCGGGGTCTACGATTTCGACAGCACCTTC ATCGGCGACGCCTCGCTCACAAAGCGCCCGATGGGCCGC GTGTTGAACCCGCTGCGCGAAATGGGCGTGCAGGTGAAA TCGGAAGACGGTGACCGTCTTCCCGTTACCTTGCGCGGG CCGAAGACGCCGACGCCGATCACCTACCGCGTGCCGATG GCCTCCGCACAGGTGAAGTCCGCCGTGCTGCTCGCCGGC CTCAACACGCCCGGCATCACGACGGTCATCGAGCCGATC ATGACGCGCGATCATACGGAAAAGATGCTGCAGGGCTTT GGCGCCAACCTTACCGTCGAGACGGATGCGGACGGCGTG CGCACCATCCGCCTGGAAGGCCGCGGCAAGCTCACCGGC CAAGTCATCGACGTGCCGGGCGACCCGTCCTCGACGGCC TTCCCGCTGGTTGCGGCCCTGCTTGTTCCGGGCTCCGAC GTCACCATCCTCAACGTGCTGATGAACCCCACCCGCACC GGCCTCATCCTGACGCTGCAGGAAATGGGCGCCGACATC GAAGTCATCAACCCGCGCCTTGCCGGCGGCGAAGACGTG GCGGACCTGCGCGTTCGCTCCTCCACGCTGAAGGGCGTC ACGGTGCCGGAAGACCGCGCGCCTTCGATGATCGACGAA TATCCGATTCTCGCTGTCGCCGCCGCCTTCGCGGAAGGG GCGACCGTGATGAACGGTCTGGAAGAACTCCGCGTCAAG GAAAGCGACCGCCTCTCGGCCGTCGCCAATGGCCTCAAG CTCAATGGCGTGGATTGCGATGAGGGCGAGACGTCGCTC GTCGTGCGTGGCCGCCCTGACGGCAAGGGGCTCGGCAAC GCCTCGGGCGCCGCCGTCGCCACCCATCTCGATCACCGC ATCGCCATGAGCTTCCTCGTCATGGGCCTCGTGTCGGAA AACCCTGTCACGGTGGACGATGCCACGATGATCGCCACG AGCTTCCCGGAGTTCATGGACCTGATGGCCGGGCTGGGC GCGAAGATCGAACTCTCCGATACGAAGGCTGCCTGA 2 Abutilon cDNA 1622 TTCAGTTTCATTCAGATCAAATCTCAAAGGAGGTTTTTC theophrasti CAATTCCCGGGGTTTGTGTTTGAACAGCAATGGTAAGTT GGGAACAATCAAGGTTCGGCCAGGAGTGGTTTCTGCTTC AACAGCAGCCACGGCTGAGAAGCCATCCAGCGCATCCGA AATTGTGCTTCAACCAATCAATGAAATTTCGGGTACTGT TAAATTACCCGGCTCTAAATCACTCTCCAATCGGATTCT GCTCCTAGCTGCTCTATCCGAGGGAACTACTGTGGTTGA CAATTTGTTGAATAGCGACGATGTTCATCACATGCTTGT CGCTTTGGGAAAACTTGGCCTTCGTGTGGAGCATGACAG 55 WO 2013/039990 PCT/US2012/054789 TGAAAAGAAACGAGCCATTGTTGAAGGCTGCGGTGGTCA ATTTCCAGTAGGGAAAGGGGAAGGTCAAGAAATTGAGCT TTTCCTCGGGAATGCTGGAACCGCAATGCGACCTCTTAC TGCTGCTATTACCGCCGCCGGTGGCAATTCAAGCTACGT ACTTGATGGTGTACCCCGAATGAGAGAGAGGCCAATTGG GGACTTAGTTACTGGTCTTAAGCAGCTGGGTGCAGATGT CGATTGTACTCTTGGCACAAATTGCCCCCCTGTCCGTAT AAATGGAAAGGGTGGTCTTCCTGGAGGAAAGGTGAAACT TTCAGGATCTATCAGTAGTCAATACTTGACCGCTTTACT CATGGCAGCTCCTTTGGCTCTTGGGGATGTGGAAATTGA GATTATTGATAAACTGATTTCAATCCCATATGTTGAAAT GACCATAAAATTGATGGAAAGGTTTGGGGTCAGTGTGGA GCACAGTAATAGCTGGGATCGATTCTTTATCCGAGGAGG TCAAAAGTACAAGTCTCCTGGAAATGCTTACGTCGAAGG TGACGCTTCAAGTGCTAGTTACTTCCTTGCTGGTGCAGC TGTTACTGGTGGGACTGTCACAGTAGAAGGATGTGGAAC AAGTAGTTTGCAGGGTGATGTAAAATTCGCTGAGGTTCT TGAGATGATGGGTGCCAAAGTTACTTGGACCGAGAACAG TGTAACCGTCACTGGACCCCCAAGAAATTCCTTTGGGAG GAAGCAATTGCGTGCTATTGATGTCAACATGAACAAAAT GCCAGATGTTGCCATGACTCTCGCTGTTGTTGCCCTTTA CGCTGATGGTCCCACTGCCATAAGAGATGTGGCAAGTTG GAGGGTGAAAGAGACTGAAAGGATGATTGCTATATGCAC AGAACTCAGGAAGCTCGGAGCAACAGTTGAAGAAGGGCC AGATTATTGCGTCATCACTCCACCGGAGAAATTAAACGT GACAGCAATAGATACTTATGATGATCACCGAATGGCCAT GGCATTCTCTCTTGCCGCCTGTGCAGAGGTTCCAGTTAC CATCAATGATCCTGGTTGTACCCGGAAAACCTTCCCTGA CTACTTTGAAGTTCTCGAGAGGGTTACAAAGCATTGAAT GGCTCGTTTTACTTCGTTATACAAGAGAAAGAAACAAAG CATGAGAGATAGGTTCGTACCACTGTTCTTAAAATCAAA GGCTGAAATCAGTTGAACCTTGTCTTCAATGTTGTCTCC TGATCTGATAATTTCTCATCGGC 3 Amaranthus cDNA 958 GCGCCCATTGACAGCTGCGGTTGCCGTTGCTGGAGGAAA graecizans TTCAAGTTATGTGCTTGATGGAGTACCAAGAATGAGGGA GCGCCCCATTGGGGATCTGGTAGCAGGTCTAAAGCAACT TGGTTCAGATGTTGACTGTTTTCTTGGCACAAATTGCCC TCCTGTTCGGGTCAATGCTAAAGGAGGCCTTCCAGGGGG CAAGGTCAAGCTCTCTGGATCAGTTAGTAGCCAATATTT AACTGCACTTCTCATGGCTACTCCTTTGGGTGTTGGAGA CGTGGAGATTGAGATAGTTGATAAATTGATTTCTGTACC GTATGTTGAAATGACAATAAGGTTGATGGAACGCTTTGG AGTATCTGTTGAACATAGTGATAGTTGGGACAGGTTCTA CATCCGAGGTGGTCAGAAATACAAATCTCCCGGAAAGGC ATATGTTGAGGGTGATGCTTCAAGTGCTAGCTACTTTCT AGCAGGAGCCGCCGTCACTGGTGGGACTGTGACTGTAAA GGGTTGTGGAACAAGCAGTTTACAGGGTGATGTAAAATT TGCTGAAGTTCTTGAAAAGATGGGTTGCAAGGTCACCTG GACAGAGAATAGCGTAACTGTTACCGGACCACCCAGGGA TTCATCTGGAAGAAAACATCTGCGCGCTATCGACGTCAA CATGAACAAAATGCCAGATGTTGCTATGACTCTTGCAGT TGTTGCCTTGTATGCAGATGGGCCCACCGCCATCAGAGA TGTGGCTAGCTGGAGAGTGAAGGAAACCGAACGGATGAT TGCCATTTGCACAGAACTGAGAAAGCTTGGGGCAACAGT 56 WO 2013/039990 PCT/US2012/054789 TGAGGAAGGATCTGATTTCTGTGTGATCACTCCGCCTGA AAAGCTAAATCCTACCGCCATCGAAACTTATGACGATCA CCGAATGGCCATGGCATTCTCTCTTGCTGCCTGTGCAGA TGTTCCCGTCACTATCCTTGAT 4 Amaranthus cDNA 490 GAGCCAAGAAACAACGCGAAATTCAGAGATAAAGAGAAA graecizans GAATAATGGCTCAAGCTACTACCATCAACAATGGTGTCC AAACTGGTCAATTGCACCATACTTTACCCAAAACCCACT TACCCAAATCTTCAAAAACTGTTAATTTTGGATCAAACT TGAGATTTTCTCCAAAGTTCATGTCTTTAACCAATAAAA GAGTTGGTGGGCAATCATCAATTGTTCCCAGGATTCAAG CTACTGTTGCTGCTGCATCTGAGAAGCCTTCATCTGCCC CAGAAATTGTGTTACAACCCATCAAAGAGATCTCCGGTA CTGTTCAATTGCCTGGGTCAAAGTCTTTATCCAATCGAA TCCTTCTTTTAGCTGCTTTGTCTGAGGGCACAACATTGG TCGACAACTTGCTGTATAGTGATGATATTCGTTATATGC TGGACGCTCTCAGAGCTCTTGGTTTAAAAGTGGAGGATG ATAATACAGCCAAAAGGGCAGT 5 Amaranthus cDNA 1682 CTAAGCCCTCGTCTTTCCCTTCTCTCTCTCTTAAAATCT hybridus TAAAATCCACCCAACTTTTTCAGCCAACAAACAACGCCA AATTCAGAGAAAGAATAATGGCTCAAGCTACTACCATCA ACAATGGTGTCCAAACTGGTCAATTGCACCATATTTTAC CCAAAACCCACTTACCCAAATCTTCAAAAACTCTTAATT TTGGATCAAACTTGAGAATTTCTCCAAAGTTCATGTCTT TGACCAATAAAAGAGTTGGTGGGCAATCATCAATTGTTC CCAAGATTCAAGCTTCTGTTGCTGCTGCAGCTGAGAAGC CTTCATCTGTCCCAGAAATTGTTTTACAACCCATCAAAG AGATCTCTGGTACTGTTCAATTGCCTGGGTCAAAGTCTT TATCCAATCGAATCCTTCTTTTAGCTGCTTTGTCTGAGG GCACAACAGTGGTCGACAACTTGCTGTATAGTGATGATA TTCTTTATATGTTGGATGCTCTCAGAACTCTTGGTTTAA AAGTGGAGGATGATAATACAGCCAAAAGGGCAGTCGTGG AGGGTTGTGGTGGTCTGTTTCCTGTTGGTAAAGATGGAA AGGAAGAGATTCAACTTTTCCTTGGTAATGCAGGAACAG CGATGCGCCCATTGACAGCTGCGGTTGCCGTTGCTGGAG GAAATTCTAGTTATGTGCTTGATGGAGTGCCAAGAATGA GGGAGCGCCCCATTGGGGATCTGGTAGCAGGTCTAAAGC AACTTGGTTCAGATGTTGACTGTTTTCTTGGCACAAATT GCCCTCCTGTTCGGGTTAATGCTAAAGGAGGCCTTCCAG GGGGCAAGGTCAAGCTCTCTGGATCGGTTAGTAGCCAAT ATTTAACTGCACTTCTCATGGCTACTCCTTTGGGTCTTG GAGACGTGGAGATTGAGATAGTTGATAAATTGATTTCTG TACCGTATGTTGAAATGACAATAAGGTTGATGGAACGCT TTGGAGTATCTGTAGAACATAGTGATAGTTGGGACAGGT TCTACATACGAGGTGGTCAAAAATACAAATCTCCTGGAA AGGCATATGTTGAGGGTGACGCTTCAAGTGCTAGCTACT TCCTAGCTGGAGCCGCCGTCACTGGTGGGACTGTGACTG TCAAGGGTTGTGGAACAAGCAGTTTACAGGGTGATGTAA AATTTGCCGAAGTTCTTGAGAAGATGGGCTGCAAGGTCA CCTGGACAGAGAATAGCGTAACTGTTACGGGACCACCCA GGGATTCATCTGGAAGGAAACATCTGCGCGCTGTCGACG TCAACATGAACAAAATGCCAGATGTTGCTATGACTCTTG CAGTAGTTGCCTTGTATGCTGATGGGCCCACTGCCATCA GAGATGTGGCTAGCTGGAGAGTGAAGGAAACCGAACGGA TGATTGCCATTTGCACAGAACTGAGAAAGCTTGGGGCAA 57 WO 2013/039990 PCT/US2012/054789 CAGTTGAGGAAGGATCTGATTACTGTGTGATCACTCCGC CTGAAAAGCTAAATCCCACCGCCATCGAAACTTATGACG ATCACCGAATGGCCATGGCATTCTCTCTTGCTGCCTGTG CAGATGTTCCCGTCACTATCCTTGATCCGGGATGCACCC GTAAAACCTTCCCGGACTACTTTGAAGTTTTAGAAAAGT TCGCCAAGCATTGAGTAACATATGGGTTCTTTAAATTGT ACGCC 6 Amaranthus cDNA 843 GAGGGTTGTGGTGGTCTGTTTCCTGTTTGGTAAAGATGG lividus AAAGGAAGAGATTCAACTTTTCCTTGGTAATGCAGGAAC AGCGATGCGCCCATTGACAGCTGCGGTTGCCGTTGCTGG AGGAAATTCTAGTTATGTGCTTGATGGAGTGCCAAGAAT GAGGGAGCGCCCCATTGGGGATCTGGTAGCAGGTCTAAA GCAACTTGGTTCAGATGTTGACTGTTTTCTTGGCACAAA TTGCCCTCCTGTTCGGGTTAATGCTAAAGGAGGCCTTCC AGGGGGCAAGGTCAAGCTCTCTGGATCGGTTAGTAGCCA ATATTTAACTGCACTTCTCATGGCTACTCCTTTGGGTCT TGGAGACGTGGAGATTGAGATAGTTGATAAATTGATTTC TGTACCGTATGTTGAAATGACAATAAGGTTGATGGAACG CTTTGGAGTATCTGTAGAACATAGTGATAGTTGGGACAG GTTCTACATACGAGGTGGTCAAAAATACAAATCTCCTGG AAAGGCATATGTTGAGGGTGACGCTTCAAGTGCTAGCTA CTTCCTAGCTGGAGCCGCCGTCACTGGTGGGACTGTGAC TGTCAAGGGTTGTGGAACAAGCAGTTTACAGGGTGATGT AAAATTTGCCGAAGTTCTTGAGAAGATGGGCTGCAAGGT CACCTGGACAGAGAATAGCGTAACTGTTACGGGACCACC CAGGGATTCATCTGGAAGGAAACATCTGCGCGCTGTCGA CGTCAACATGAACAAAATGCCAGATGTTGCTATGACTCT TGCAGTAGTTGCCTTGTATGCTGATGGGCCCACTGCCAT CAGAGATGTGGCTAGCTGGAGAGT 7 Amaranthus cDNAC 1554 ATGGCTCAAGCTACTACCATCAACAATGGTGTCCATACT palmeri ontig GGTCAATTGCACCATACTTTACCCAAAACCCAGTTACCC AAATCTTCAAAAACTCTTAATTTTGGATCAAACTTGAGA ATTTCTCCAAAGTTCATGTCTTTAACCAATAAAAGAGTT GGTGGGCAATCATCAATTGTTCCCAAGATTCAAGCTTCT GTTGCTGCTGCAGCTGAGAAACCTTCATCTGTCCCAGAA ATTGTGTTACAACCCATCAAAGAGATCTCTGGTACTGTT CAATTGCCTGGGTCAAAGTCTTTATCCAATCGAATCCTT CTTTTAGCTGCTTTGTCTGAGGGCACAACAGTGGTCGAC AACTTGCTGTATAGTGATGATATTCTTTATATGTTGGAC GCTCTCAGAACTCTTGGTTTAAAAGTGGAGGATGATAGT ACAGCCAAAAGGGCAGTCGTAGAGGGTTGTGGTGGTCTG TTTCCTGTTGGTAAAGATGGAAAGGAAGAGATTCAACTT TTCCTTGGTAATGCAGGAACAGCGATGCGCCCATTGACA GCTGCGGTTGCCGTTGCTGGAGGAAATTCAAGTTATGTG CTTGATGGAGTACCAAGAATGAGGGAGCGCCCCATTGGG GATCTGGTAGCAGGTCTAAAGCAACTTGGTTCAGATGTA GATTGTTTTCTTGGCACAAATTGCCCTCCTGTTCGGGTC AATGCTAAAGGAGGCCTTCCAGGGGGCAAGGTCAAGCTC TCTGGATCGGTTAGTAGCCAATATTTAACTGCACTTCTC ATGGCTACTCCTTTGGGTCTTGGAGACGTGGAGATTGAG ATAGTTGATAAATTGATTTCTGTACCGTATGTTGAAATG ACAATAAAGTTGATGGAACGCTTTGGAGTATCCGTAGAA CATAGTGATAGTTGGGACAGGTTCTACATTCGAGGTGGT CAGAAATACAAATCTCCTGGAAAGGCATATGTTGAGGGT 58 WO 2013/039990 PCT/US2012/054789 GATGCTTCAAGTGCTAGCTACTTCCTAGCCGGAGCCGCC GTCACTGGTGGGACTGTCACTGTCAAGGGTTGTGGAACA AGCAGTTTACAGGGTGATGTAAAATTTGCCGAAGTTCTT GAGAAGATGGGTTGCAAGGTCACCTGGACAGAGAATAGT GTAACTGTTACTGGACCACCCAGGGATTCATCTGGAAAG AAACATCTGCGTGCTATCGACGTCAACATGAACAAAATG CCAGATGTTGCTATGACTCTTGCAGTTGTTGCCTTGTAT GCAGATGGGCCCACCGCCATCAGAGATGTGGCTAGCTGG AGAGTGAAGGAAACCGAACGGATGATTGCCATTTGCACA GAACTGAGAAAGCTTGGGGCAACAGTTGAGGAAGGATCT GATTACTGTGTGATCACTCCGCCTGAAAAGCTAAACCCC ACCGCCATTGAAACTTATGACGATCACCGAATGGCCATG GCATTCTCTCTTGCTGCCTGTGCAGATGTTCCCGTCACT ATCCTTGATCCGGGATGCACCCGTAAAACCTTCCCGGAC TACTTTGATGTTTTAGAAAAGTTCGCCAAGCAT 8 Amaranthus Genom 18729 CCCAAATGAAATTTGACCTATTTTAGTAGGTTATCTTCT palmeri ic TCAATGTCTTCTTCAATGCCTCTTTATAAACCCAGCTAC TGATTTGTATCCCACAAGCCATTGTTCTTCTTCAATTTA TTCCACTTTGTTCTTCAATCTTCACCTTTCTTCTTCCAT TGTGTTCTTCCTTCTTCACTATTAACCCTACGCAAGCCC TCTTCAAATGTATTACAATTTTGAATCAAATAATACAAT TGATGCTCATAATTAACACCAAGACTAGTGACCACCAAA TCATTAAGATCAAACCATGAAATGCAATCAGGATCAAGT GAAAGGCTTCTATATTCCCCACCCACATAATTCAACCCT ACCCCAGTCCTTTTGAATTTACCCCCATACCAAAACATC ACTTGAAATTTTTCAAAATTATTAACCTAAAAAAACAAC ACAATTGAACATAATTACCAATGCATTTCTATAACAACA AAGAAAACATTAAAGAATCAAAGATTAAAGTGAGGAATG GCAAAGAAATTACCATGGTTTGATTGAGAACAAGAAGAC CCAAAATTCGTCTGCACAGCCCCAAAATTTTCGCACAGA GCAGCAATACCACCCCCAAAATTCGACACTGTTGATAAA AAATAAACCCTAATTTTTTTGGGAAATTACAGTTGATGA ATGTGAGTGTTGATTATGGCGTGAAGCTTGATGATTATG AATGACAATTGTGCTTCAAGTTTTTGAAATTTTGAAGTT TTGAAGGAAGATGGTGTGAAGGAATGGTAGAACAGGAAA TGAAGTTAAGGGTATGCCTTTTTGGGTTGAATGTTTATT TTATGGAATTAAAGAATATGAAAGATCATACTCTAACCT GCAATAGTAGGTCAAATTTCATTTGGGGGTGCCACGAGC AAATACACTTGAAAGGTGAGATTATTCATAAATAATCAA TACTTGGGATTATTCACATAGGTTTGCGAATAGTTCGGA TTATTCCCAACAATTTTTCCTTAAGATTATAATTAAAAA ATCCCCAAAAGATGAAAAAAAGAGAAAGCATGTAAAACA CGCGAATCAGACCGGTCCACTCTTGTTTTAATTTGAGAC AATTTTGATGTTGAGTCATCCCACACCAACCCCAAAAAA TTCAACAACAAACTCTTATAATGATTCCCTCTACTCTAC TAGAGTCTACACCAACCCACTTTCTCTTTGCCCACCAAA ACTTTGGTTTGGTAAGAACTAAGCCCTCTTCTTTCCCTT CTCTCTCTTAAAAGCCTAAAATCCACCTAACTTTTTCAG CCAACAAACAACGCCAAATTCAGAGGAAGAATAATGGCT CAAGCTACTACCATCAACAATGGTGTCCATACTGGTCAA TTGCACCATACTTTACCCAAAACCCAGTTACCCAAATCT TCAAAAACTCTTAATTTTGGATCAAACTTGAGAATTTCT CCAAAGTTCATGTCTTTAACCAATAAAAGAGTTGGTGGG CAATCATCAATTGTTCCCAAGATTCAAGCTTCTGTTGCT 59 WO 2013/039990 PCT/US2012/054789 GCTGCAGCTGAGAAACCTTCATCTGTCCCAGAAATTGTG TTACAACCCATCAAAGAGATCTCTGGTACTGTTCAATTG CCTGGGTCAAAGTCTTTATCCAATCGAATCCTTCTTTTA GCTGCTTTGTCTGAGGTATTTATTTCTCAACTGCGAAAA CAATCTCTATTTGATATTGGAATTTATATTACATACTCC ATCTTGTTGTAATTGCATTAGTACATACTTATGTTTTGA CCTTTGTTCGTTTGTTTGTTGAATTGGTAGTGTTGAGAA TTTGAATCTAATTATTTGTTTTTCCATGTGAATTTAATC TGATTAAATCCACTTCTTATTTATGTTAAGTTGCAATGA TGTTTGCCAAACGGTTATCATTGAAGGATAAGTTCGCCT ACTTTTGACCCTCCCAACTTCGCGTTGGTAGAGCCATTT TATGTTATTGGGGGAAAGTAGAAAGATTTATTTGTTTTG CCATTCGAAATAGTAGCGTTCGTGATTCTGATTTGGGTG TCTTTATAGATATGATATATGGGTTATTCATGTAATGTG TAGGTTTATGCATTATGTTGGATGCATGTCTGGTGTTAT TGCTGTAAATGGATGAATGTTGTTATTTGGAGACATTTT TTCATTCATTTTTTCCCTTTTTAATTGGAACTGGAAGAG GGAAAGTTATTGGGAGTAATTAAAAGGTTGTGAGTTCGA TACACTGCATCAAAGACGAAGAACTTGACATAGATGTTG AAGGCTAATCCTTATCACTGCTTGAATTCAATATGTATC TGAAAATTTTACCCCTCTATATGCATCTGTTTTTGCTAA TAAAGTGTTTTTGGACTATCATGTTTTGTGATGCTTAAG AGGGTGATATTACTGAGATAAATGGAAATATCAAAATAA CATCTATTGTGAAGTAGTTTTAGAGGCTTTTGATTGGTG CTTCGACTTTGGATTTACTTGCATCCTAGATTGACTCAG TTTGTGCAATCTGAAAATGATTTCATCATGGTATGAATA TGGTTCAAAAACAAGGCTGCATCTCATCGAACACGTTGT AAAGATTTAAAATTAATCAAATTGATATTTCTAGCATTG TAAAGGCTTAAAAAACTGTATCTCAGGCTATATTAGGGA TTCTCATGCTCTTGACCGATATTTAGGTGTTACGATAAC CACATCACTCCTACGATCGTTACCAGATGTTTGCACTTT GTTATGTGTTACAAGAGATAAGTGTTGCATGCAGTGGAT CCCTTGTGATTTTGTTCTAGGTAGACAGTGTTGTTTTTG AATTTCAAAGCAGGAATTATAACGAGATTTGATATTAGG GTTTGAATTTTTTTAAAAGTTTTTTGCATTCCTCCGATT TGCAACACGGTTTACCTACTGTTTATTTGAATTTTTTGT GTGAGAAAAGGCTTACAGGCTTGCTCTTGTATATGTGTA TGTATTTGCTTTGTGGTTAAATATGCTGCATGTTGTAAT GAAAACTCTGCCCGGGGATGGTGGGCTTACACGCCAAAG AAAAAGATTGTTTTCCACAACTAAAAATATCCCATTGGC AACAGCGTGCAATTATTTAGGGAATGGTGTTAGAGCATT AAAATTGGAAAATAAATGAGCTCTCATTTTGTTCAAACC ATGAGAATTTTCCCCTGGTCCAATATTCAGCGTTTTGTT TCATTTGTAAAAATTACGATCATATTTCTCTTTAGTGAA GCAACTGATTGGAAAACTTTGGTATATGCCATGTTTCTT TCCAAGTTAAAGAGTTCCCAGGCATCATCCTCAATGATC TTCCTCTATATTCCTGTACAATATTGTTGATAGGAAGTT CATTCATGCCAATAACAATATGTCTCTTGCGAATTTCTA GAAGACCAGAAATTTGTTGTGACCTGTGGAGTTCTTCCA AAAGTATCCTCTGTGCGACGCATGAAAAAAGCCTTTGGG CTAGACTACTGAGATGCAGCTGCCTGGTAATTCATGCCT CTCTCCCAAGAGAGTACGAGAAGTCATTTATAGCCGCTT AAGAGAGCCAAGGATCAATTTAGGCGTGTTCTATTTCCA TATCTTAATGTATCACTGAAGTTTAGCAAGTAAACAAAC 60 WO 2013/039990 PCT/US2012/054789 ATCACAATCCCTGATGCTTGCATAGTCATGGCAAATGTT ATACTCTTTGTTTACATATGAAAAACCAGATATTACTCC ATATTTTTAGAAACCAGCAACCAAAGGAGCTTAAATGGT CCCTGCTCCTAAGTCATATCTCTTGGCAATGGGGTGTTT GTAGATCTTGAGTGCTGCCAGTCCACTTACTGTAATGCA ATACATCAATATTGAGCTAGTTTCTCATGGGAAAAAACC ATAGAAATGGGACAAATTTGATGTTAATGTTCTGTAATC CAACTTGAGGATTAGTTTTATCACATAAAAGCTACATTG AAAGTTCTATTATTATTTTGAGTTTGCATCTTATGTTGT TTTTCCTTTGTGATTTTATCCATTTTCTTAACTAGTTAT TCGTTTCCTGAAGTTTTTAGTGTCATAACTCCTAATCAC AATCATGCTACAGGGCACAACAGTGGTCGACAACTTGCT GTATAGTGATGATATTCTTTATATGTTGGACGCTCTCAG AACTCTTGGTTTAAAAGTGGAGGATGATAGTACAGCCAA AAGGGCAGTCGTAGAGGGTTGTGGTGGTCTGTTTCCTGT TGGTAAAGATGGAAAGGAAGAGATTCAACTTTTCCTTGG TAATGCAGGAACAGCGATGCGCCCATTGACAGCTGCGGT TGCCGTTGCTGGAGGAAATTCAAGGTTTGTCCAATTATA TTCTTTATGTGAGTGTTGTTTTTTGTGTTAGTTTCAATC ATGAAGGTACTAATGCAGAAGCCGTACCCCTGAAATTTT CTTATTTTGTATATATCAATTGGTAATTGATGTAAGATA TTTTTCCGAGAGGAATAAAAAACAGGGGGATAGAGAATA TTAAAGTATTGTTCTATCACATTAACTTTTTATCAAAGG TGTACATTGTGTTTGTGAAGTTTATAGAGCTAAAGGGAT GGAAGGGAAGGGGATTGAAGAAGAGGAGAAAAGAAGAAG ATCCTCCTTTGAATACCAAGGTTTGAACGGAAGGGAGAA GGAGGAAACTCTAAACAATATGGAGATGAACTGATGAAG TTTTTGGATCAGAACCGCTTGAGAATCAGAGTTAAGCCA TGTGAAAGTCTATGAGCATGACTTCACCTGGTTAATAAT TTTAAGCTCTCAACTTCTCATCCTCTTTTCTTTGTCGAA AATGTCATGTCTTCATGTGATACGTGCTTACATAATCGT TTCTTTTGTAAAGCGATTGTCTCTCCAGATTTCTCCCCT TACGAAAATAATCCTTGAAGGTTGAAGAAATCCCTTCAT TTCCTTTTCCCCTATTTCTCTACCCTTCCTACTTTGGTG AAGGATTTTGTATCCCTCCCTTTTCATGGTCTATAGTGT TAGATATTCAAACTTAAGCTTCTCAAGTTTCATGTGGGT TCTGATTATTATTTTATATATGCATTACCAAGGATTCAA GGTAATTTGAACCAATCAAGACCAGAACCGGATATGAAT TCTTCAACCTAGTCTGAACTTGTACATCTAAAACATGCT AGTTACAACTGAAATATGATCAACTTCTATAGCCTATAA GACTCTCACCTTCATTTGTAGGTTGCCACATAGCACGTA TTGTCGATCCATCCATCCTCATTATTTGACTCATCAAAT AAAGGAAC CAC T CAT GT GAAAT T C C T GTC C TACAAAATA ATCCATCTTCCTCATCTCATTTGTATTCATGTAGTTTGC TTCCTCAATCCTACAAGTAAAAGGACAACTGCGATTCAA CTCTTGGACCTATTTGACAGTAAATCCACGAATATTAGG ACAATCACGTTGGTAATGAACCATCGCTTGGCGCTTGAA ACATTTGATTTCCTCAAAATCCTTTGCTTCCCCCAACAT TTCATCCTTTGCTTTCCACATTAAAGTTGGTGCCCGAAC CTCCATAGCCACAAACTTGGTTGTAGACAACACACCAAC GTTTCTACCTCTAATAGAGATAGGATTTGTATAAGCCTT ACTCTTCTTAGATCCTTATGTTTCATAGACCTTTTTCAT CTTGCACGTATCATCAAAAGACAAGTTGGTATGTATCTC AGGCTTCACGCACAAGTCAACATCCTTATCACCATACCT 61 WO 2013/039990 PCT/US2012/054789 CAATATGACAAGCCCTACCTCTCAATCTTCTACAAAGCT ATAGATCTTCCATCTCAATGCAAGGAACTTCAACACACG TATAAACTTTTTTTGAATTTAATTGTTCAAAGGAAAAAA CCTTTCTTTCATGTGCATTTTTATGTCAACATAGCTATT AATCAACGTCTTTCCTCTTGTACGAGCTAATTCTCAATA CCTTTAAGCCCACATGAAGCCTTCTTCTTGAGCTTGAAT TTAAAAAACTGGAAAATTTGCTTTTCGTACGGAGTTCTT GTTGTTGTAAAAACACTCCGAACTTCTCTCCTATTCACG ATGATCTTTTGGGTGTAAGGACATACTATCAAAATTTTC TACGTTATCCTGAAGCCATGATCATCCACCTCGCAATAT GCTCAACTTTCAGTTCACGCTGATTCAATATCTGCGTGA ATAGATTGATCAAGCTTGCCATTTGCTCAAGAATAGTTG AGTTTTCCTCTTGTAATACTCGATTCCTCTCTTCTGTTT TTTTAGTCATCCTACTATTTGCTAGCGACAATCTCACAA GAATATAAGAGGGGATTCTCATCTATTATAACGCACTAC TCTGTACCTAAGGAACTAGTGTGGGTGTCTTATTTTTGT CCTCTCCTCGTAGGATATAAAAGAGATGTGTATTTGTGA ATGATTCAACATAAAACAAAAGTATGTAGGCTCTTAGAT TATACCATCTCATTAACATATGATGAACTCTTACATATG CTCCTTCACATATATTTGTTTTTTTGGGGTCATTTATTC TAGTAGTCCATTGATATTGAATCCCTTAGTTATGGCATT ATTGTCCGTGCACTGTCTCAGGAGAATAGATGGATTGTT ATTGCTTTTTCTGTATCTGATGGTAATACAAAGATTGCA ACATTTGCTAGACCTTGCTGTTTGGATATAGAAAGAAAA TTATTTGCCATTCATTTCCAAGGGGTCGAATGTAGCCTT ATCCTTATTCGTGATAACAAAGAGATTGATTTGTAGTCC TTACATTTGAAAATCCTGGACTTCACTGAATTTATGTAA CTGTTGCATGCCATGAAATGGAATACTTTATTGATTATG TGTTTGGGATATGTAAGCTGAAGAAGGCAATTTCCCAGC TCCTATTAATGCTATCTACACTTCATATTATCCTTTCTG ATATAGTTTACTTTTCTTTGCATGTGTCGAATTAGTTAT GTGCTTGATGGAGTACCAAGAATGAGGGAGCGCCCCATT GGGGATCTGGTAGCAGGTCTAAAGCAACTTGGTTCAGAT GTAGATTGTTTTCTTGGCACAAATTGCCCTCCTGTTCGG GTCAATGCTAAAGGAGGCCTTCCAGGGGGCAAGGTAATG TGACTAAACTTCTTTATGTTTTGTTAGATTTTGGGTTTT ACTCCATCTAATTCAATGAATGATGATTCATGCGTCAAT TTCTTGGTAGCAATTCCTTTCCCTACCTAACTATGACTT CTCTGATTGACCTTTTCTATGAGGTGGGGAATAGTGTTT TTAATGTGAGGAAAAGAGAAACCCGGGGTATGAGCTTTA GCATGATAGAGTATGTATTTGATACTAAAACTGCAAATT AAGTTGGAATCAAGAATAAGAAGACTTATACAGTATAAA TCAACAGAGGTGTCTGCTGTGTATATGTGTAATAGACAG TTATAGTTAGCAGGAATTCAGGAGATAAAATGAAGATGG TGTTGATGAAACTTAACAGACAATT CAGAAAACAAAGTT TGAGTAGTAAGTAGACTTTTGAGAGGCTGCTTCTCTCTC AAATGAGCTATAAGTTCTAACAAAAGTCT CAATACATAA TTTAGATAATAATCAGATGCCTCTCTCACGCTCCATCCC TTTATTATCTAGATTTCTTGATTTTTTTTCATAACTTAT GCAACTTATTTCAGCCTCTTCCTTCATTCCACCTTCTAC TTGAAATAAAATGCAATCTCTACCTTGTTTCTTTATGGT TTGTTCATTTTAATAAAGATTTAGTATGAAAGTCAATAT TGCTTTTGCATTGTTGTTTGTCTAAGATCCTAATGGCAA GTCCACATAAGATGTTTGTTGGTATATGCTAGGTTATTA 62 WO 2013/039990 PCT/US2012/054789 GGATCGGGATTCTACTTAGGATCGTTGAGGAGGTAGGAT TGAAATAGGTAGAATCGGTTCGTACTTCGTAGGATTGTG CCATGCTACAAATATGCATTGATGTGCTTTGGATTATTT GTTATCAATTATATTTGTTCTTCTGTTCAGTTTTAAGGT GTAAGTAAAAACTTATTCGATTTCATTTATTAAGTTTTG AAAAAAATACTTTAATAATCACTTTTAAACTGCAAATTG AAAAAAAATTGCATTTTTTAGTGATGTTTTTTTTTTTTT GAATATCAGTGATGTTGATATAATTATTTTATAGAATAT TTATACATAATTGAAATCTTGATTATATGAAAATATTTT ACGATTGAAACTACTTTTATAGGATCGGATCGTTTGATT GTAGGATCTTAGAATCGTATTATGATCCTACCACCTAAA TTTTTGAGCTAGTTCTACCACATTATGACTCTACCTAAG ATCCGGATCGATTGTTTATTTTTAGATCGTAGAATCGTA GATCAAAATCGAGACTCTAATATCTATGGGTATATGTGT TAAATTATTAGTCAGTAGAACAATTCTCTTTTTCTTGGT AAATAAAATCGTACGATACTTTAGTCCGGGGGGCGCGCT TTGTGTCCTGTACGGTAAGTATCCTGTGACAAAACTGTA CTTCAGGTGTCTTCTTCACTCTTGGGAAAGTGTAAATGT CTTTTGTCCCGATTAAGGAAGATTTTATGAGAAATTTTC CCACATGCTTGGCACCAATTTGTTTTTATTTAGTAGAAG AAGAAATTATGTATAACATGCATACTCAGGATGGTAGTG AATATGAAAT GAAGAAAGGAGGTAAAGTT GCAT GCTGGA AACTTATAAAGAGATGATTCATTCAAAATTTTGATATTC CTAATAGCATAGTTGTGGTTTTCAATTTCACAGTCATGA AGTAAGAACCTCTCTAATATTATCCATTTGTTTTGTGAA TTGATCAAATTAGAACTACAATTTCAATGTTTGTTGTTA ATGAGAAGTTCTAGCATAGTTGTGGTTTTCAATTTCACA GTCATGAAGTAAGAACCTCTCTAATATTATCGATTTGTT TTGTAAACTGTTTGCAGGTCAAGCTCTCTGGATCGGTTA GTAGCCAATATTTAACTGCACTTCTCATGGCTACTCCTT TGGGTCTTGGAGACGTGGAGATTGAGATAGTTGATAAAT TGATTTCTGTACCGTATGTTGAAATGACAATAAAGTTGA TGGAACGCTTTGGAGTATCCGTAGAACATAGTGATAGTT GGGACAGGTTCTACATTCGAGGTGGTCAGAAATACAAGT AAGTCTCTCATCTTATATTACATGTCCTTTTAACGTGTC TCCATTAGTAGACTGAAAACACATGTAAATACATCAGAT CTCCTGGAAAGGCATATGTTGAGGGTGATGCTTCAAGTG CTAGCTACTTCCTAGCCGGAGCCGCCGTCACTGGTGGGA CTGTCACTGTCAAGGGTTGTGGAACAAGCAGTTTACAGG TATAATGTTAACCCTTACCCTTCACATTGTTCTGCTAAA TTCTAGAGGACCCTTTCAATTCTGGGTGGGATAAGCACG GCAATTTGACCGCAAAAAAATTGCAAAATTATTCTGCTG ATAGAACATCTCGAGATGAGATCATATTGAGTTTTGGCG T CAACATAAAC C TAAT CAAATAAT GAAAAATACAAACAT CATATGGTTTCTTTTGTCTTTATGACTAGACACTCTCTA TTATTCCTTGATTGGGATCTTATTTGAAATTGCTGTGTA GCCTACACCTCATGTTCAGATTTTGTTCGTATACCAGAC TTTTCTTGATTGGGATCTTATTTGTCCCCTGGATTTTGC ATAGGGTGATGTAAAATTTGCCGAAGTTCTTGAGAAGAT GGGTTGCAAGGTCACCTGGACAGAGAATAGTGTAACTGT TACTGGACCACCCAGGGATTCATCTGGAAAGAAACATCT GCGTGCTATCGACGTCAACATGAACAAAATGCCAGATGT TGCTATGACTCTTGCAGTTGTTGCCTTGTATGCAGATGG GCCCACCGCCATCAGAGATGGTATGCTTAACTCTTTTCA 63 WO 2013/039990 PCT/US2012/054789 TTGAACTGTGGCTTATGTAGACTCTTTCAAATATTGATA ATGAAATTTAGTGTGTCATAAGAAAATCGGAATTTGGAC TTGTTTTTGTTTTGGAATATTCAAACAGCTAGAAAGATG TTTTTTTTGCTCTAATGGTGGTTAAACTATCACTGTCCT TGATGGGAAATTATGATTTTTGCTGTCCCCAATGTGTTT ATTGGCATATCTTGATACAATTAAGTGAGGGACCACTTT GCACCATTAAGTTTCTCATAGTCATCACCATTTCTAAAT AATTAAAATTTAGTATTTTGTAGACTTGTTATGAAATGA CGTTAATTTTTAACAATACTTAATGGTCTTAAAGGGGTG TTTGGGAAATGACTGCTGATTAAAATTGTTTTGACTAGA TGATTTTTATCAACTGATTTGACCTATTGAATTTGAACA TGCTTTTAGGAATAGCTTGTTCAAAAATAGCTTCTTCAG AACAATAAGTTGTTTCAATCAACTAATATACCAAACACT AACCAATTATTTACAATTGTGCCAAAATAAGCTAAAATT GTCAAATCAACTATTATGCAACCTCAGGATGTGTTCCGG GGATATGAATTGAAACCCATCTTTGGCAGAGTAGAGATA AGACGAAAATTGATCCAATCTTAGGGATGAATGTTGAGA TATTATTTCCATAAATATACTGTGGTGGCATTTAGGGTT TTTTATTTAACAAGGGGTGTTTAGTTTGGAGAACTTTTT ATTGAAAACCTGTTTTCTCCATATTCCCATACTGGGTTG ACAATGAAAATTTGAAAATTAGGGTTGAAAAGAATTATT CCTTCCATTATTAGCTTACAAACTTATATAGTTGGATGA AAATTAAATTTCATTCACTTTCACTCCATCTCCCTTGGT AGCATTATCGTATT CCAT CAAACAAAACAAAAGAAAAGT AGTAATAATTAACGTTTAATTGGAAAATTGTTTCTCATG GAAAATGTTCTCCGCCAGACCAAATACTTTCGGAACGAG GAAGCATTTTGGAATAAAGAACCTTGTGCTTGGATTAAT ATATTTGTCTATGAGATAGTTTTCTCTAGAGTTTACTTG TATGTTTATTAACTGAACACGCCTCCTTTGCAATCAAAG AAAAAGGAATTATTTCACCTCTAAGCATACCGAAAACAT CGACGCAAAATACATGTCAAGATGTGTAATGATTTTGTT ATGTGAATTAACAGTGGCTAGCTGGAGAGTGAAGGAAAC CGAACGGATGATTGCCATTTGCACAGAACTGAGAAAGGT TAGCAGCCTTTTACATTCTCGAAAGCTGTAATTGTTCTT GAGTAATATATATTCAAACTATAACTGATGTTATTTTGC ATTCCTATCAATACATTCAGCTTGGGGCAACAGTTGAGG AAGGATCTGATTACTGTGTGATCACTCCGCCTGAAAAGC TAAACCCCACCGCCATTGAAACTTATGACGATCACCGAA TGGCCATGGCATTCTCTCTTGCTGCCTGTGCAGATGTTC CCGTCACTATCCTTGATCCGGGATGCACCCGTAAAACCT TCCCGGACTACTTTGATGTTTTAGAAAAGTTCGCCAAGC ATTGAGTAGCTATATACGAGATCCTTAAATTGTACGCCG AAGGTTTTGATTTGAGTCTAATAGTAGATAAAAGGCTAT AAATAAACTGGCTTTCTGCTTGAGTAATTATGAAATTCT TTGTATTATGTTTGTGAGATTTTAAGTAGCTTATAAATT ACAATGTACTAAAGTCTAGAAATAAGTTATGTATCTTTT AAATCAATGAGAAATGCATACTTGAAAGGCTTGACCTTG TATTCGTGACCTAAAGAGTACTAACTTTGGAGTTTCCAA GTCATTTGTTTATCTCATTTTTTTTTAATTTTTGATTTA AATTGTTTATTTTCATGAGTAATCATGTACTCCCTCCGT TCCTTTTTGTTTTTCCACCTTACTAATACAGGTAGTTCC ATAAGTTTTTCCACTTTAGAATACTTTCCATTTTTGGAA AGTTTTCATCCCAGTTCCCACATTTACTCCTTAAAACCC CACTTTCCTTACTTTACACTACTATTTAATTATTTTCTC 64 WO 2013/039990 PCT/US2012/054789 TCTTATACTTCCAATACAAGTATTACATTATACTATTAT TTAATTATTTTTTCTCTCATACTTTCAATACAATCATTA CTTTTCACTACTATGAAGTAATTAAAATAATACCCATTA CCACCAAAGATTCCATTTTTCTTAATCTTGGTGAAAAAC CCAAATAGGAACAT CAAAAAGGAAC GGAGGGAGTATC CA AAATAAGGGAACTAATTGTTATTTTTACTATTTTTCATT ACTTTCTAATTGATTCTCCCACCTCTTTAACAATAAAAT TCCTTTAGTTAGCAAATTCAAAAAAAAAAAATTCCTTTA GTTAGCTATTTAATTAATTTTGTTTTCCTAATTTGACTA ATACTTCTTGAAAATTTACCTACAATCCAAGCGATCTCT TTGAAATTAAATAGGAATAGTGTGTTGGGGAGCTGGCAG TTATAGAATACGGGTGATCAAAACAAATTACAAGATCGA TTCACATATGGATTTTCGGATAATGAAAATCGTAATCCG GATTATATATCGAATATCCGGTTTATTTATTCTTAATTA TTTTTTGCTTTTTCTAAAACAAAATTGTATTTTATTACA CCAAGTAGAAGAGTGAAACGTTGAAACTTTGATGTGTTT AAAGAAGAGACACTTGAAAGATGACTTGACTTAGAGAAG TGAAACATAAAAAAATGAAATTTGTAAGAGCATATAACA TTAGATACAAAAGAATATAAAAGGAGAATATATGTAGAT GATAATTGTAACTGAATTTGCAAGTTGTATAATCAGGCG TCCAACATGCGTATTTGGAGTAAAGAGATAAGTCCAAGC AACATAGTTGTCTATGACCATTTTACATTATGGTATGAT GATTCATGACTACTGAGCTTGTTTGTTGATTAGTCTTGT GCACTTCTAATATACAATCTTAAATAGCCTCTTTTTATC TTCTTTTTGTGACTGGTATGTAACATGGCTACATATATT CTGTGAGTAATCTTTTAATATTCTTTCTAGTTTCCTTTG TTCTTATCTTGTGTTACTCTAGTCGTATTACTGGACGAA CTTAACTTCATAACTTTCAGTTCAATGTGCTGAACCTTT ATGTTCTTTTGAAATTGGGGCGTGGTGTACCCAACGTGC AGAATCTATTTGTGAGCTTTGGTATAAATGAGCGATTAC AATGAAAGGAGCACTCTATGATTTTTGCTATGCCAAGCA AGCCTGGTGATTTTAGTCAGTTTTTGATTTTCCTAATGT CCTTCCAGCACCATTTAACGGTTAGTTTGGTAATGAAAT TTGGAAAATGTCTGTATTAGCAAAAGTCAAACTACTTTT AATGACTTTCACGAGTCTCTTCATCAAGATGTTTGATGT GTGCATGTATGTGTGCGCGGAAATAGTATCTACTCCTCT TGATTTACTCAGTTCTCGAACAAAATTTGACTGCAACAG ACAATATGTAACCTTAAAATGCTTTGACACGCGATCAAT TTTCAATCTAGATTTGGATTTATGATCAAAGTAAAGAAG GTTTGATGTAAAAAGCCTAATAAAAGAAGATATTGTTCT AATGATATCAATTGAAGTCCAATTCTGCCAGATATATCT ATAGCTTAAAACTAGGGCATTATATACATGCACCGAAAT GTAAGTAGCAAATCAACAACGATAAAATTAAGAGCTTAA CTAGTTGAGCAAGAGCTACCCCTCGGAATCAATCAGTCT CAGTTTTAGCGACTTTTTATCCTTGAATGTCATTTTGTA AGTTATCTACTTTGAAATATCGAGAATTTTTTCATAGTT ATATAGGAAGGTCATTAATGAAGAAATTATTTTGAATAA GTTAGAACTTCAAAATAAACATTTAACTACAAATCATTG ACAAACCTAGTACATTGCATAGGGATCCATTATCACAAC TTCCAAAGAAGATTGTAACTTAAACCCTAATTTGTTTCC AAGCTTGCAATTTCAACAAAATCTAACAAATTCCAACTT TTTAAGCTTTAAAACCACGTACATTGGACATTTAATTAT ATCATTCCTCAGGATTCTAACTTATATATAACATTAATT ATATTACCTAATATACTATAAAATTTAGAATTTAAAATC 65 WO 2013/039990 PCT/US2012/054789 TGAAATTTATCACCAAATTACGTGTCAAAGTATATTATT TTATATTTATCTTTTCATCGTGTTTCCTGATTAACTCTT TCGGATATATTATTACTCTTGTTAACAATACCCTCAAAT GTTCATTTGCTTTTTCCCTTATAAAAAATCGGAAAACTT TACATAGCATGAATAAGGTTTGATGAAACACCATTGTAG CACTTTTTTTGTTTTTGTATGATAGCAACAAGATTACAA GTTTATAAAAACACTTAGCAAATTATGTTAAATACAAGC CTATTATGTTAATTTTGGACTTTTTTTAAATGTTTTTTT AGATTTATATTTACGATATACTTGTATATAAATAAAACA AAATTTAAAAATCAAAATTTTCCTCCCAACTTCCTCCCT TTCCTTGTTAGTTGTCACAACCCCTAACCCAACCATCCT TTCCCTTGTGTCAACAAAGAGTACTTAAAATTAGATATC GTATTATTGTAAAATTCAAATTATCATAAGAGCATGATG TACATGTAACAAGAAGGTCAAACAAAAGGGAGTTAAAAT CAATTTAGCTTTTTACTAAATTCTTAAAATCTCGCAACG AGAAAATTAAATATAAGTTAGATTTTTGCATTATTTACT AAAAGTTATAAATCTATAGGATGAGCTATATGAATTAAA TGTTTAGGAAATTTAAAATTATACCCAGTTCTCATATGA ACATCAAATATTACACGGTAT CTATAAACAAAAACCGTA ATTAAAAGCAGTCTACGTTAATTTGAAAATCTCCTTATA TTAATCAAGGAATCAGATTAAAACTCTATTAGGTTGTGT CTTAAACTATTTTTTATTTTACATTTATACATTAAAAAA TTTATTCGAGGGTATATTAAAAATAAATAATATTCTTCA TAATCTTAGCTAATCCTAATTCCTAACTATCAAATCAAT GGTTAACACAGTAAATTACCCTCTAATCCCCCAACAGCC CATTGTTTGTTTGGAAGTGTAAGCATAAAAAACCTCAAT AATACTAATTAGTGTGCTGTAACCATGGTGTCTATGACG TGTGTTGGGAGTTGAGAGCAAATAGAATTCTGTGCCAAT TGAAGGCTAAAACTTAAAACCAACCAAACACTCTTTTAG AGACGTATTTTAAGTCCAGCCTATCAAAGACAATACCTA CCTACTGTATTCTTAATGTCAACTTACATTATCCTTAAT GCCTACTTTCAATATGTTAAATGTCTACTTACATCATTT TTAATGCATACTTACAGTATTTTAAACAATTTATAACGG GTCAGCCCAATCAGAGATGGTCTCTCAAACAGACCGTCT AAGACCGTCTCTCACAAGAATTTGTGCAAGCCCTTAATC CTCTAAACAAAGATCTCATTCCCTGGTTTTTGTTCCCTT ACAACTCAACCTTTGCTTTGTTTTGTATAAACAACCTTC CCTTTTTTATGCTTTCCTTTGCCAGATTTCTAATCTTCC ATCCCCCAACTAGCCTACATTGTTTCATTGAATAATTCT AATTAACACTTCTCAATACTTGTACTTACCGAATTCTTA GTCATTTGTATTTAAAGATTATGCCCACGTTCACTCCCC CTCCTTGATAATCACGTTTTTGCTAATCCCAATCTTCTT GATATTACTCATCTTCACCTTTATGAACTTGTAAGCTTT GTATATATACACCCACCATATGTATATCCTTTCATATTA AGTACTTCATCATATCCTTAATACTACTTTCAAAAAAAG GAAAAACACAATAAAAAGGTTAGTTATGGCTCAAATT CA ACAATTCACTAGCATTTCTTATGCTCCTTCTAAGAGAAA GGGGAATGGGTTCACTAGGAAGTGTGCCTCTTTAATTAA AGAGCAACACGCTCGAATCTATATCCTTAGAAGATGTGC TACAATGCTTCTTTGCTCGTACATTGAAGCCGATGATGA CTAAACATCTCCTTTATCTTAGCCTTACGTTCTGATGTA ATCCGGTGCATACTAGTACTAGCTACAGTATATACGTAA GTCATAACTATGCCTTTTCCCACTCTCCATTGTATACCA GGCTCGAGCAGTAATGCACCTTCGTTTAATCGCTTAATC 66 WO 2013/039990 PCT/US2012/054789 ATCCAAATTTTTGACCCAAAAGGCAATAATTCGATTGGG TTTTTTCACTTTTTAGTTTGGATGGTTGCTGGTTTAAGA ATTTTATGGGTGCATTGCTGCTTTTTTGTAA-ACCAGCAG TAGTGCTGATGAGGCTTACAAGCATCAATTCAATGCCGC TCAGAGAACTGGACTTGAGATTTAGAGATGGCTGAA-AAT GGGGTTATATACTTAAACTTATGTTGAATGTAACTCTAA GAGTTTTATCCTAAAAGATATATATCTGATAATACGACT TTGAGAGAGTATTATCATTGTGTTGTGTTACTAATCTTT AT GAGAAAAATGAAAT GAAAT TGAGTGGATATGTAATAC TTCAACATTCCAAAGCATATTCTTTTGTTGATATGAACA AT CCTT TAAGCTTT CAAC TAAATGGAAACATATACATAG ATTTGCATACAAA-AATCAGTATACATGATCAAGAA-ACCT TTGAGCAATTTAAATGTTGTCAGCCCAGAATTGAGTTCT GAATACATAAACGCAGTCTAAATTCAACTCAA-ATGCATT TAGAATCTGAAAATTTTTTGGTTGCATCAAA-ATTTATAT TAAAAAAATCACAATTACAACACTTTGGAGCTCCAA-AAC CTGATATTACACCGATTCTAAATTTGCTCTTCAAATTAA AATCCCTAGCAACATTGACTATTAATTACTGATCAATTA AAATCC CTAACAAT TT CAT CAT CAATTCT TAGAAA-ATTA AAATCCAGCAACAATCACAA-ACTAAATCAAATTCAACGC TAAAACACAAATCAAA-ACTCATTATACGCACCAGCTTCA GCATCAAGAAGACCGCCATAAGGATCTTGATCTCCAAAA CT GGGAACCC TAAGTACACCGTGTAATCCAACAATTACA GCAGAAATCACACAGGCAACCATCAGATTCATCCAAGAA TGAGCGATAAACAAAGCGATAATCGTAAT TACAGCAAGA ACGCCAAAA-ACGATGCGATCGTCAACGATGAACCCCGTA AT TTCAAGAGGAAAAATGCGAGGAT TAAAATAAAGAAAG TAC CAAGATAAT GACAC CACAAACAC GAGAAGGAGT GAG AGAGGAC GTAAAGC GAGAGTAAAGAAGAAGAT GAT GAGA AAGACGTTAATGTAGTTAACT CGGAAGTGAGTTAGAT TT GAGTTGAACCGAGTTGTGGCGTCAGAA-AGGGATACTGGG AATGAAAGGGCGGAGATATCGAAA-AATTC CGAC CATGGT CTGGTTGTTGTTGCGGCGGGGTAGTCATCGGAAGATGGT TGTAAAGACATGTTTGATTTGAGATTTTGTTTTTCTTTG ACGAAGATTTGGGTTGTCGTGTGGTGGATGGCGAATTTC TAATTACTCTCCATATATTGTTCAATTTTCATATACTTT ATCATTTCTTTATTCTTACTAATTCACTAACTTTATACC TCAAAAAAAATAAATTAATTTACTAACTTTATCGACATC GTCTTATCGGGAGACTACTTCAATTAGATTATCTCATTT CC CTAT TATT TTAAAAA-AT TATAT TATATAC GAGTAT GT CCAATTTTCGTTGTGTTTTTTAA-ATTTTCTTTCATTAAA GGGCT GC T TGTAT GGGT C CGT CTCACAAT GAGAGGTC TT ATACAAGACTTGTTGTTCTTAATTATATAGAGTCAGAGG CC GGAGGAAAGAGGGTAGCGACAA-ATTATAATC GTAC GA CGTACC TATC CAAAAAGAGGACAAGGAGAAATGTGTGTA CTCAATTTATCACATAA-AAA-ATAGATTTATACATAA-AGA AAGT CAGT TC TTAT TTATAT GAGTT TGAAAA-AT TAT CAA TTTGTAATATAAACATGTTAGATCTGTTAGCAATATATG AGTTTTATTTTTTTAATTTTTACAAGTATTTCGAAA-ATA AT TATAAC GATC GT GTT CAAC CCAT GTAATAA-AGATC TA GTTGAATAATAAATCATTTTTATAAAAGAAAATGTTACT TGCTAGATTT GCAACTAAATGAAAACAAAATGAATATAA AGTAGTAATAT GT TATAATACAT TTAAA-AT TAAAATAAT ____ ____________AAC TAT TT TAT TAT CATACAT TCACAAGAT GAAATAT GC 67 WO 2013/039990 PCT/US2012/054789 ATTACATCATGTACATATATTATATACTTATATATACTT ATACCCCTACATAATTTTCTCTACTATTTATTATTCCTT ATACATACTATATAACCAAAAATATTTATGCTATAATTA TCAAATAAAAGATGCATACATATACCTAACTATATATTT CTTCACTAGGAATTCATTACAAAAAAAAAAAAAGAAAAT TGTCAAAAATAAATCAACTTTTGCTCAATCCTTTAAAAA TAAACCCAACTATTAATTATTTTCAAATAAATCCATCTA CTTGATATAACTGCTGAAAATAAATCCAACTAATGAATA TTCCTAATTGCTTGATCACAAAGAAGCTTTGAAGATGCT TATAAACAA 9 Amaranthus Genom 668 GAACATATGAGTGATCAATTGTGGAGTTAAACTGATCAA palmeri ic TATCTATCTAAGTATTTGATGTTTTATGATCTAACTCAA TTTTGAACGTATAAGCTTCAATTATCGTTTTCAAAATAA GTATTTCAAAGTCTATAAAGATATTGTATAAGTTTTAGT TCATTTTGAATAAGTTAATAGTTAAATTATGACATATAA TTTGACCATGATATTTTATAATCTAACTTAATTTTGAAC TTTTAATATTCAATTATCGTTTTAAAAATAAGTATTCAA ATTGTATAGATATATTGTATAACATTTTGTTCAAATTTA ATTATTGATAGTTTTATTTATTGACCATTCATTTTGAAA TTCATCCATAGAATGATAGAATAACACTATTTTTTATAT AACTTCGTTCTAAAATTTTAAAGCATAACCAGAAGTATT AGGTAGCAATTTATCACTTTAACATCAAAATTGATCACT TATAGGTTCAAATTGAAACTTTTACTTTAATTGATATGC TTAAGTACTACTTTAAATTGAAAATTAATATCTTTAAGG TTAAAATTGATACCTTTAAGATTAGGAAAAATTGTCGGG AATAATCCGAACTATTTGCAAACTGCTGTGAATAATCCC ACGTATTGATTATTTATGAATAATCCCACCTTTCAAGTG TATTT 10 Amaranthus Genom 13434 TATCTTTAAGGTTAAAATTGATACCTTTAAGATTAGGAA palmeri ic AAATTGTCGGGAATAATCCGAACTATTTGCAAACTGCTG TGAATAATCCCACGTATTGATTATTTATGAATAATCCCA CCTTTCAAGTGTATTTGCTCGTGGCACCCCCAAATGAAA TTTGACCTATTTTAGTAGGTTATCTTCTTCAATGTCTTC TTCAATGCCTCTTTATAAACCCAGCTACTGATTTGTATC CCACAAGCCATTGTTCTTCTTCAATTTATTCCACTTTGT TCTTCAATCTTCACCTTTCTTCTTCCATTGTGTTCTTCC TTCTTCACTATTAACCCTACGCAAGCCCTCTTCAAATGT ATTACAATTTTGAATCAAATAATACAATTGATGCTCATA ATTAACACCAAGACTAGTGACCACCAAATCATTAAGATC AAACCATGAAATGCAATCAGGATCAAGTGAAAGGCTTCT ATATTCCCCACCCACATAATTCAACCCTACCCCAGTCCT TTTGAATTTACCCCCATACCAAAACATCACTTGAAATTT T T CAAAAT TAT TAAC C TAAAAAAACAACACAAT T GAACA TAATTACCAATGCATTTCTATAACAACAAAGAAAACATT AAAGAATCAAAGATTAAAGTGAGGAATGGCAAAGAAATT ACCATGGTTTGATTGAGAACAAGAAGACCCAAAATTCGT CTGCACAGCCCCAAAATTTTCGCACAGAGCAGCAATACC ACCCCCAAAATTCGACACTGTTGATAAAAAATAAACCCT AATTTTTTTGGGAAATTACAGTTGATGAATGTGAGTGTT GATTATGGCGTGAAGCTTGATGATTATGAATGACAATTG TGCTTCAAGTTTTTGAAATTTTGAAGTTTTGAAGGAAGA TGGTGTGAAGGAATGGTAGAACAGGAAATGAAGTTAAGG GTATGCCTTTTTGGGTTGAATGTTTATTTTATGGAATTA AAGAATATGAAAGATCATACTCTAACCTGCAATATTAGG 68 WO 2013/039990 PCT/US2012/054789 TCAAATTTCATTTGGGGGTGCCACGAGCAAATACACTTG AAAGGTGAGATTATTCATAAATAATCAATACTTGGGATT ATTCACATAGGTTTGCGAATAGTTCGGATTATTCCCAAC AATTTTTCCTTAAGATTATAATTAAAAAATCCCCAAAAG AT GAAAAAAAGAGAAAGCATGTAAAACAC GCGAATCAGA CCGGTCCACTCTTGTTTTAATTTGAGACAATTTTGATGT TGAGTCATCCCACACCAACCCCAAAAAATTCAACAACAA ACTCTTATAATGATTCCCTCTACTCTACTAGAGTCTACA CCAACCCACTTTCTCTTTGCCCACCAAAACTTTGGTTTG GTAAGAACTAAGCCCTCTTCTTTCCCTTCTCTCTCTTAA AAGCCTAAAATCCACCTAACTTTTTCAGCCAACAAACAA CGCCAAATTCAGAGGAAGAATAATGGCTCAAGCTACTAC CATCAACAATGGTGTCCATACTGGTCAATTGCACCATAC TTTACCCAAAACCCAGTTACCCAAATCTTCAAAAACTCT TAATTTTGGATCAAACTTGAGAATTTCTCCAAAGTTCAT GTCTTTAACCAATAAAAGAGTTGGTGGGCAATCATCAAT TGTTCCCAAGATTCAAGCTTCTGTTGCTGCTGCAGCTGA GAAACCTTCATCTGTCCCAGAAATTGTGTTACAACCCAT CAAAGAGATCTCTGGTACTGTTCAATTGCCTGGGTCAAA GTCTTTATCCAATCGAATCCTTCTTTTAGCTGCTTTGTC TGAGGTATTTATTTCTCAACTGCGAAAACAATCTCTATT TGATATTGGAATTTATATTACATACTCCATCTTGTTGTA ATTGCATTAGTACATACTTATGTTTTGACCTTTGTTCGT TTGTTTGTTGAATTGGTAGTGTTGAGAATTTGAATCTAA TTATTTGTTTTTCCATGTGAATTTAATCTGATTAAATCC ACTTCTTATTTATGTTAAGTTGCAATGATGTTTGCCAAA CGGTTATCATTGAAGGATAAGTTCGCCTACTTTTGACCC TCCCAACTTCGCGTTGGTAGAGCCATTTTATGTTATTGG GGGAAAGTAGAAAGATTTATTTGTTTTGCCATTCGAAAT AGTAGCGTTCGTGATTCTGATTTGGGTGTCTTTATAGAT ATGATATATGGGTTATTCATGTAATGTGTAGGTTTATGC ATTATGTTGGATGCATGTCTGGTGTTATTGCTGTAAATG GATGAATGTTGTTATTTGGAGACATTTTTTCATTCATTT TTTCCCTTTTTAATTGGAACTGGAAGAGGGAAAGTTATT GGGAGTAATTAAAAGGTTGTGAGTTCGATACACTGCATC AAAGACGAAGAACTTGACATAGATGTTGAAGGCTAATCC TTATCACTGCTTGAATTCAATATGTATCTGAAAATTTTA CCCCTCTATATGCATCTGTTTTTGCTAATAAAGTGTTTT TGGACTATCATGTTTTGTGATGCTTAAGAGGGTGATATT AC TGAGATAAATGGAAATATCAAAATAACATCTATTGTG AAGTAGTTTTAGAGGCTTTTGATTGGTGCTTCGACTTTG GATTTACTTGCATCCTAGATTGACTCAGTTTGTGCAATC TGAAAATGATTTCATCATGGTATGAATATGGTTCAAAAA CAAGGCTGCATCTCATCGAACACGTTGTAAAGATTTAAA ATTAATCAAATTGATATTTCTAGCATTGTAAAGGCTTAA AAAACTGTATCTCAGGCTATATTAGGGATTCTCATGCTC TTGACCGATATTTAGGTGTTACGATAACCACATCACTCC TACGATCGTTACCACATGTTACCACATGTTTGCACTTTG TTATGTGTTACAAGAGATAAGTGTTGCATGCAGTGGATC CCTTGTGATTTTGTTCTAGGTAGACAGTGTTGTTTTTGA ATTTCAAAGCAGGAATTATAACGAGATTTGATATTAGGG TTTGAATTTTTTTAAAAGTTTTTTGCATTCCTCCGATTT GCAACACGGTTTACCTACTGTTTATTTGAATTTTTTGTG TGAGAAAAGGCTTACAGGCTTGCTCTTGTATATGTGTAT 69 WO 2013/039990 PCT/US2012/054789 GTATTTGCTTTGTGGTTAAATATGCTGCATGTTGTAATG AAAACTCTGCCCGGGGATGGTGGGCTTACACGCCAAAGA AAAAGATTGTTTTCCACAACTAAAAATATCCCATTGGCA ACAGCGTGCAATTATTTAGGGAATGGTGTTAGAGCATTA AAATTGGAAAATAAATGAGCTCTCATTTTGTTCAAACCA TGAGAATTTTCCCCTGGTCCAATATTCAGCGTTTTGTTT CATTTGTAAAAATTACGATCATATTTCTCTTTAGTGAAG CAACTGATTGGAAAACTTTGGTATATGCCATGTTTCTTT CCAAGTTAAAGAGTTCCCAGGCATCATCCTCAATGATCT TCCTCTATATTCCTGTACAATATTGTTGATAGGAAGTTC ATTCATGCCAAGGGATAACAATATGTCTCTTGCGAATTT CTAGAAGACCAGAAATTTGTTGTGACCTGTGGAGTTCTT CCAAAAGTATCCTCTGTGCGACGCATGAAAAAAGCCTTT GGGCTAGACTACTGAGATGCAGCTGCCTGGTAATTCATG CCTCTCTCCCAAGAGAGTACGAGAAGTCATTTATAGCCG CTTAAGAGAGCCAAGGATCAATTTAGGCGTGTTCTATTT CCATATCTTAATGTATCACTGAAGTTTAGCAAGTAAACA AACATCACAATCCCTGATGCTTGCATAGTCATGGCAAAT GTTATACTCTTTGTTTACATATGAAAAACCAGATATTAC TCCATATTTTTAGAAACCAGCAACCAAAGGAGCTTAAAT GGTCCCTGCTCCTAAGTCATATCTCTTGGCAATGGGGTG TTTGTAGATCTTGAGTGCTGCCAGTCCACTTACTGTAAT GCAATACATCAATATTGAGCTAGTTTCTCATGGGAAAAA ACCATAGAAATGGGACAAATTTGATGTTAATGTTCTGTA ATCCAACTTGAGGATTAGTTTTATCACATAAAAGCTACA TTGAAAGTTCTATTATTATTTTGAGTTTGCATCTTATGT TGTTTTTCCTTTGTGATTTTATCCATTTTCTTAACTAGT TATTCGTTTCCTGAAGTTTTTAGTGTCATAACTCCTAAT CACAATCATGCTACAGGGCACAACAGTGGTCGACAACTT GCTGTATAGTGATGATATTCTTTATATGTTGGACGCTCT CAGAACTCTTGGTTTAAAAGTGGAGGATGATAGTACAGC CAAAAGGGCAGTCGTAGAGGGTTGTGGTGGTCTGTTTCC TGTTGGTAAAGATGGAAAGGAAGAGATTCAACTTTTCCT TGGTAATGCAGGAACAGCGATGCGCCCATTGACAGCTGC GGTTGCCGTTGCTGGAGGAAATTCAAGGTTTGTCCAATT ATATTCTTTATGTGAGTGTTGTTTTTTGTGTTAGTTTCA ATCATGAAGGTACTAATGCAGAAGCCGTACCCCTGAAAT TTTCTTATTTTGTATATATCAATTGGTAATTGATGTAAG ATATTTTTCCGAGAGGAATAAAAAACAGGGGGATAGAGA ATATTAAAGTATTGTTCTATCACATTAACTTTTTATCAA AGGTGTACATTGTGTTTGTGAAGTTTATAGAGCTAAAGG GATGGAAGGGAAGGGGATTGAAGAAGAGGAGAAAAGAAG AAGATCCTCCTTTGAATACCAAGGTTTGAACGGAAGGGA GAAGGAGGAAACTCTAAACAATATGGAGATGAACTGATG AAGTTTTTGGATCAGAACCGCTTGAGAATCAGAGTTAAG CCATGTGAAAGTCTATGAGCATGACTTCACCTGGTTAAT AATTTTAAGCTCTCAACTTCTCATCCTCTTTTCTTTGTC GAAAATGTCATGTCTTCATGTGATACGTGCTTACATAAT CGTTTCTTTTGTAAAGCGATTGTCTCTCCAGATTTCTCC CCTTACGAAAATAATCCTTGAAGGTTGAAGAAATCCCTT CATTTCCTTTTCCCCTATTTCTCTACCCTTCCTACTTTG GTGAAGGATTTTGTATCCCTCCCTTTTCATGGTCTATAG TGTTAGATATTCAAACTTAAGCTTCTCAAGTTTCATGTG GGTTCTGATTATTATTTTATATATGCATTACCAAGGATT 70 WO 2013/039990 PCT/US2012/054789 CAAGGTAATTTGAACCAATCAAGACCAGAACCGGATATG AATTCTTCAACCTAGTCTGAACTTGTACATCTAAAACAT GCTAGTTACAACTGAAATATGATCAACTTCTATAGCCTA TAAGACTCTCACCTTCATTTGTAGGTTGCCACATAGCAC GTATTGTCGATCCATCCATCCTCATTATTTGACTCATCA AATAAAGGAACCACTCATGTGAAATTCCTGTCCTACAAA ATAATCCATCTTCCTCATCTCATTTGTATTCATGTAGTT TGCTTCCTCAATCCTACAAGTAAAAGGACAACTGCGATT CAACTCTTGGACCTATTTGACAGTAAATCCACGAATATT AGGACAATCACGTTGGTAATGAACCATCGCTTGGCGCTT GAAACATTTGATTTCCTCAAAATCCTTTGCTTCCCCCAA CATTTCATCCTTTGCTTTCCACATTAAAGTTGGTGCCCG AACCTCCATAGCCACAAACTTGGTTGTAGACAACACACC AACGTTTCTACCTCTAATAGAGATAGGATTTGTATAAGC CTTACTCTTCTTAGATCCTTATGTTTCATAGACCTTTTT CATCTTGCACGTATCATCAAAAGACAAGTTGGTATGTAT CTCAGGCTTCACGCACAAGTCAACATCCTTATCACCATA CCTCAATATGACAAGCCCTACCTCTCAATCTTCTACAAA GCTATAGATCTTCCATCTCAATGCAAGGAACTTCAACAC ACGTATAAACTTTTTTTGAATTTAATTGTTCAAAGGAAA AAACCTTTCTTTCATGTGCATTTTTATGTCAACATAGCT ATTAATCAACGTCTTTCCTCTTGTACGAGCTAATTCTCA ATACCTTTAAGCCCACATGAAGCCTTCTTCTTGAGCTTG AATTTAAAAAACTGGAAAATTTGCTTTTCGTACGGAGTT CTTGTTGTTGTAAAAACACTCCGAACTTCTCTCCTATTC ACGATGATCTTTTGGGTGTAAGGACATACTATCAAAATT TTCTACGTTATCCTGAAGCCATGATCATCCACCTCGCAA TATGCTCAACTTTCAGTTCACGCTGATTCAATATCTGCG TGAATAGATTGATCAAGCTTGCCATTTGCTCAAGAATAG TTGAGTTTTCCTCTTGTAATACTCGATTCCTCTCTTCTG TTTTTTTAGTCATCCTACTATTTGCTAGCGACAATCTCA CAAGAATATAAGAGGGGATTCTCATCTATTATAACGCAC TACTCTGTACCTAAGGAACTAGTGTGGGTGTCTTATTTT TGTCCTCTCCTCGTAGGATATAAAAGAGATGTGTATTTG TGAATGATTCAACATAAAACAAAAGTATGTAGGCTCTTA GATTATACCATCTCATTAACATATGATGAACTCTTACAT ATGCTCCTTCACATATATTTGTTTTTTTGGGGTCATTTA TTCTAGTAGTCCATTGATATTGAATCCCTTAGTTATGGC ATTATTGTCCGTGCACTGTCTCAGGAGAATAGATGGATT GTTATTGCTTTTTCTGTATCTGATGGTAATACAAAGATT GCAACATTTGCTAGACCTTGCTGTTTGGATATAGAAAGA AAATTATTTGCCATTCATTTCCAAGGGGTCGAATGTAGC CTTATCCTTATTCGTGATAACAAAGAGATTGATTTGTAG TCCTTACATTTGAAAATCCTGGACTTCACTGAATTTATG TAACTGTTGCATGCCATGAAATGGAATACTTTATTGATT ATGTGTTTGGGATATGTAAGCTGAAGAAGGCAATTTCCC AGCTCCTATTAATGCTATCTACACTTCATATTATCCTTT CTGATATAGTTTACTTTTCTTTGCATGTGTCGAATTAGT TATGTGCTTGATGGAGTACCAAGAATGAGGGAGCGCCCC ATTGGGGATCTGGTAGCAGGTCTAAAGCAACTTGGTTCA GATGTAGATTGTTTTCTTGGCACAAATTGCCCTCCTGTT CGGGTCAATGCTAAAGGAGGCCTTCCAGGGGGCAAGGTA ATGTGACTAAACTTCTTTATGTTTTGTTAGATTTTGGGT TTTACTCCATCTAATTCAATGAATGATGATTCATGCGTC 71 WO 2013/039990 PCT/US2012/054789 AATTTCTTGGTAGCAATTCCTTTCCCTACCTAACTATGA CTTCTCTGATTGACCTTTTCTATGAGGTGGGGAATAGTG TTTTTAATGTGAGGAAAAGAGAAACCCGGGGTATGAGCT TTAGCATGATAGAGTATGTATTTGATACTAAAACTGCAA ATTAAGTTGGAATCAAGAATAAGAAGACTTATACAGTAT AAATCAACAGAGGTGTCTGCTGTGTATATGTGTAATAGA CAGTTATAGTTAGCAGGAATTCAGGAGATAAAATGAAGA TGGTGTTGATGAAACTTAACAGACAATTCAGAAAACAAA GTTTGAGTAGTAAGTAGACTTTTGAGAGGCTGCTTCTCT CTCAAATGAGCTATAAGTTCTAACAAAAGTCTCAATACA TAATTTAGATAATAATCAGATGCCTCTCTCACGCTCCAT CCCTTTATTATCTAGATTTCTTGATTTTTTTTCATAACT TATGCAACTTATTTCAGCCTCTTCCTTCATTCCACCTTC TACTTGAAATAAAATGCAATCTCTACCTTGTTTCTTTAT GGTTTGTTCATTTTAATAAAGATTTAGTATGAAAGTCAA TATTGCTTTTGCATTGTTGTTTGTCTAAGATCCTAATGG CAAGTCCACATAAGATGTTTGTTGGTATATGCTAGGTTA TTAGGATCGGGATTCTACTTAGGATCGTTGAGGAGGTAG GATTGAAATAGGTAGAATCGGTTCGTACTTCGTAGGATT GTGCCATGCTACAAATATGCATTGATGTGCTTTGGATTA TTTGTTATCAATTATATTTGTTCTTCTGTTCAGTTTTAA GGTGTAAGTAAAAACTTATTCGATTTCATTTATTAAGTT TTGAAAAAAATACTTTAATAATCACTTTTAAACTGCAAA TTGAAAAAAAATTGCATTTTTTAGTGATGTTTTTTTTTT TTTGAATATCAGTGATGTTGATATAATTATTTTATAGAA TATTTATACATAATTGAAATCTTGATTATATGAAAATAC TTTACGATTGAAACTACTTTTATAGGATCGGATCGTTTG ATTGTAGGATCTTAGAATCGTATTATGATCCTACCACCT AAATTTTTGAGCTAGTTCTACCACATTATGACTCTACCT AAGATCCGGATCGATTGTTTATTTTTAGATCGTAGAATC GTAGATCAAAATCGAGACTCTAATATCTATGGGTATATG TGTTAAATTATTAGTCAGTAGAACAATTCTCTTTTTCTT GGTAAATAAAATCGTACGATACTTTAGTCCGGGGGGCGC GCTTTGTGTCCTGTACGGTAAGTATCCTGTGACAAAACT GTACTTCAGGTGTCTTCTTCACTCTTGGGAAAGTGTAAA TGTCTTTTGTCCCGATTAAGGAAGATTTTATGAGAAATT TTCCCACATGCTTGGCACCAATTTGTTTTTATTTAGTAG AAGAAGAAATTATGTATAACATGCATACTCAGGATGGTA GT GAATATGAAATGAAGAAAGGAGGTAAAGTTGCATGCT GGAAACTTATAAAGAGATGATTCATTCAAAATTTTGATA TTCCTAATAGCATAGTTGTGGTTTTCAATTTCACAGTCA TGAAGTAAGAACCTCTCTAATATTATCCATTTGTTTTGT GAATTGATCAAATTAGAACTACAATTTCAATGTTTGTTG TTAATGAGAAGTTCTAGCATAGTTGTGGTTTTCAATTTC ACAGTCATGAAGTAAGAACCTCTCTAATATTATCGATTT GTTTTGTAAACTGTTTGCAGGTCAAGCTCTCTGGATCGG TTAGTAGCCAATATTTAACTGCACTTCTCATGGCTACTC CTTTGGGTCTTGGAGACGTGGAGATTGAGATAGTTGATA AATTGATTTCTGTACCGTATGTTGAAATGACAATAAAGT TGATGGAACGCTTTGGAGTATCCGTAGAACATAGTGATA GTTGGGACAGGTTCTACATTCGAGGTGGTCAGAAATACA AGTAAGTCTCTCATCTTATATTACATGTCCTTTTAACGT GTCTCCATTAGTAGACTGAAAACACATGTAAATACATCA GATCTCCTGGAAAGGCATATGTTGAGGGTGATGCTTCAA 72 WO 2013/039990 PCT/US2012/054789 GTGCTAGCTACTTCCTAGCCGGAGCCGCCGTCACTGGTG GGACTGTCACTGTCAAGGGTTGTGGAACAAGCAGTTTAC AGGTATAATGTTAACCCTTACCCTTCACATTGTTCTGCT AAATTCTAGAGGACCCTTTCAATTCTGGGTGGGATAAGC ACGGCAATTTGACCGCAAAAAAATTGCAAAATTATTCTG CTGATAGAACATCTCGAGATGAGATCATATTGAGTTTTG GC GT CAACATAAAC C TAAT CAAATAAT GAAAAATACAAA CATCATATGGTTTCTTTTGTCTTTATGACTAGACACTCT CTATTATTCCTTGATTGGGATCTTATTTGAAATTGCTGT GTAGCCTACACCTCATGTTCAGATTTTGTTCGTATACCA GACTTTTCTTGATTGGGATCTTATTTGTCCCCTGGATTT TGCATAGGGTGATGTAAAATTTGCCGAAGTTCTTGAGAA GATGGGTTGCAAGGTCACCTGGACAGAGAATAGTGTAAC TGTTACTGGACCACCCAGGGATTCATCTGGAAAGAAACA TCTGCGTGCTATCGACGTCAACATGAACAAAATGCCAGA TGTTGCTATGACTCTTGCAGTTGTTGCCTTGTATGCAGA TGGGCCCACCGCCATCAGAGATGGTATGCTTAACTCTTT TCATTGAACTGTGGCTTATGTAGACTCTTTCAAATATTG ATAATGAAATTTAGTGTGTCATAAGAAAATCGGAATTTG GACTTGTTTTTGTTTTGGAATATTCAAACAGCTAGAAAG ATGTTTTTTTTGCTCTAATGGTGGTTAAACTATCACTGT CCTTGATGGGAAATTATGATTTTTGCTGTCCCCAATGTG TTTATTGGCATATCTTGATACAATTAAGTGAGGGACCAC TTTGCACCATTAAGTTTCTCATAGTCATCACCATTTCTA AATAATTAAAATTTAGTATTTTGTAGACTTGTTATGAAA TGACGTTAATTTTTAACAATACTTAATGGTCTTAAAGGG GTGTTTGGGAAATGACTGCTGATTAAAATTGTTTTGACT AGATGATTTTTATCAACTGATTTGACCTATTGAATTTGA ACATGCTTTTAGGAATAGCTTGTTCAAAAATAGCTTCTT CAGAACAATAAGTT GTTT CAATCAACTAATATACCAAAC ACTAACCAATTATTTACAATTGTGCCAAAATAAGCTAAA ATTGTCAAATCAACTATTATGCAACCTCAGGATGTGTTC CGGGGATATGAATTGAAACCCATCTTTGGCAGAGTAGAG ATAAGACGAAAATTGATCCAATCTTAGGGATGAATGTTG AGATATTATTTCCATAAATATACTGTGGTGGCATTTAGG GTTTTTTATTTAACAAGGGGTGTTTAGTTTGGAGAACTT TTTATTGAAAACCTGTTTTCTCCATATTCCCATACTGGG TTGACAATGAAAATTTGAAAATTAGGGTTGAAAAGAATT ATTCCTTCCATTATTAGCTTACAAACTTATATAGTTGGA TGAAAATTAAATTTCATTCACTTTCACTCCATCTCCCTT GGTAGCATTATCGTATTC CAT CAAACAAAACAAAAGAAA AGTAGTAATAATTAACGTTTAATTGGAAAATTGTTTCTC ATGGAAAATGTTCTCCGCCAGACCAAATACTTTCGGAAC GAGGAAGCATTTTGGAATAAAGAACCTTGTGCTTGGATT AATATATTTGTCTATGAGATAGTTTTCTCTAGAGTTTAC TTGTATGTTTATTAACTGAACACGCCTCCTTTGCAATCA AAGAAAAAGGAAT TAT T T CAC CT C TAAGCATAC C GAAAA CATCGACGCAAAATACATGTCAAGATGTGTAATGATTTT GTTATGTGAATTAACAGTGGCTAGCTGGAGAGTGAAGGA AACCGAACGGATGATTGCCATTTGCACAGAACTGAGAAA GGTTAGCAGCCTTTTACATTCTCGAAAGCTGTAATTGTT CTTGAGTAATATATATTCAAACTATAACTGATGTTATTT TGCATTCCTATCAATACATTCAGCTTGGGGCAACAGTTG AGGAAGGATCTGATTACTGTGTGATCACTCCGCCTGAAA 73 WO 2013/039990 PCT/US2012/054789 AGCTAAACCCCACCGCCATTGAAACTTATGACGATCACC GAATGGCCATGGCATTCTCTCTTGCTGCCTGTGCAGATG TTCCCGTCACTATCCTTGATCCGGGATGCACCCGTAAAA CCTTCCCGGACTACTTTGATGTTTTAGAAAAGTTCGCCA AGCATTGAGTAGCTATATACGAGATCCTTAAATTGTACG CCGAAGGTTTTGATTTGAGTCTAATAGTAGATAAAAGGC TATAAATAAACTGGCTTTCTGCTTGAGTAATTATGAAAT TCTTTGTATTATGTTTGTGAGATTTTAAGTAGCTTATAA ATTACAATGTACTAAAGTCTAGAAATAAGTTATGTATCT TTTAAATCAATGAGAAATGCATACTTGAAAGGCTTGACC TTGTATTCGTGACCTAAAGAGTACTAACTTTGGAGTTTC CAAGTCATTTGTTTATCTCATTTTTTTTTAATTTTTGAT TTAAATTGTTTATTTTCATGAGTAATCATGTATCTTTCT TATTCTAACCAAATGTAATACTCCTTCCAACTCTCTTTA AACGTCCACACTCTGGGCACAGAGTGTAATAGTGTGGTG GTTGGAGTCTTTTAAGTGATTATAATAATTGTAAATGTG GTAGTTAGAGTATTTTAAGTAATGTAGGTGGGGTATTAT GGTCTTGTTGAACATAGGATATTTAGGTAAAAAATCTAT GCAAAAAAAGGAAAGTAAGCAAATAAAGCGAATTGACCT GAAAAGAAAAGTGGACATGTATAGTGAGTTGGAGGAAGT ATTTTTAATTTCGGCAAATTAATCTTAAATGTCGTATTT TCTTTTATGATAAGTTTTTCGAATACTTTTACTTTCATG GGACAACTTTACCATTAATATCATCCTCACTTACCCCAT TTAACAATCAACTGACATAATAATTAAAACATAAATCTA ATCTTAAAGTTTTGGTCTAATGTCTCAATAATGATTAAT TTTATCGGACAGATGCCCTCAATAAGTACTTAAAATTAA TCCATTGTTTTTGCATGCTTTACTTAAATGTTTAATGAT AAATAACTTTTGGTCTAAATTCTTTAGGAAATAAACGCT AAAAAAGATTTAGAAACAGTCCCTATTAAACTAATTTGT TACTTATATTTACAAAAGTTTCTATTTGTTCCATGAAAT GTATACTACAAAAACTTGATATTTTTGCTTGTCATGTTC ATTTTCATTTGGTTTGCAAAATGTTGTTTATATTGATTT TGTGATGTTTATCTGATCTTCAATGCACCAAGGAAAAAT ATAACTTTTCATTTTGTTGTGCTACCAAAGTCCATTAGT ATTTAAAGTATGGCAAGAAAAAAAGATAAACAGTTGCTG AAGACGTCAATTAAATTTCGATTAAAGATCAAACTAAAA TTGATAAAAAGATGTAAGATGTTTGTTATTATGTAATAC AATTTGACGTAGTTTTTGACGTTTTTATTTAAATATAAA AATTGGCCTATTTTTAATTTAACTGTTGTTTGCGTTTTC GAAAATCCTAATTTTCACGCATTTAAAGACTTTTTATGT AATGAAAAATAATTAGAGTTTTAAAAAAGTAAACCTCCT TTAATATAGACCCAAAAGAGACCCAAAGAGAACGCAACA CATTGCCTAAGAGAAAAAAGTATGAGTTGATCAATAATA AAAAAAATTTCGATCAATATCTCTCTTAAAACTATGAGG CATGAGCAATGACAACCTATTTTAGTTTCCTAAATAAAA TTTGGAGGATTGGTAGTTCCCATGGCAATGCAATTGAGT TAAAATTAGGGTTTTAAAAAAAGTAAACATCCTTAAATC ATAGATCCAAAGAGAACAACGCACACTACAACATAATTT GTTTTTAGTAGGATATAT 11 Amaranthus Genom 38 ATATTTAATTTAAATGTCACTATTACAAATTTCTTATA palmeri ic 12 Amaranthus cDNA 1911 AAACTTTGGTTTGGTAAGAACTAAGCCCTCTTCTTTCCC palmeri TTCTCTCTCTTAAAAGCCTAAAATCCACCTAACTTTTTC AGCCAACAAACAACGCCAAATTCAGAGAAAGAATAATGG 74 WO 2013/039990 PCT/US2012/054789 CTCAAGCTACTACCATCAACAATGGTGTCCATACTGGTC AATTGCACCATACTTTACCCAAAACCCACTTACCCAAAT CTTCAAAAACTCTTAATTTTGGATCAAACTTGAGAATTT CTCCAAAGTTCATGTCTTTAACCAATAAAAGAGTTGGTG GGCAATCATCAATTGTTCCCAAGATTCAAGCTTCTGTTG CTGCTGCAGCTGAGAAACCTTCATCTGTCCCAGAAATTG TGTTACAACCCATCAAAGAGATCTCTGGTACTGTTCAAT TGCCTGGGTCAAAGTCTTTATCCAATCGAATCCTTCTTT TAGCTGCTTTGTCTGAGGGCACAACAGTGGTCGACAACT TGCTGTATAGTGATGATATTCTTTATATGTTGGACGCTC TCAGAACTCTTGGTTTAAAAGTGGAGGATGATAGTACAG CCAAAAGGGCAGTCGTAGAGGGTTGTGGTGGTCTGTTTC CTGTTGGTAAAGATGGAAAGGAAGAGATTCAACTTTTCC TTGGTAATGCAGGAACAGCGATGCGCCCATTGACAGCTG CGGTTGCCGTTGCTGGAGGAAATTCAAGTTATGTGCTTG ATGGAGTACCAAGAATGAGGGAGCGCCCCATTGGGGATC TGGTAGCAGGTCTAAAGCAACTTGGTTCAGATGTAGATT GTTTTCTTGGCACAAATTGCCCTCCTGTTCGGGTCAATG CTAAAGGAGGCCTTCCAGGGGGCAAGGTCAAGCTCTCTG GATCGGTTAGTAGCCAATATTTAACTGCACTTCTCATGG CTACTCCTTTGGGTCTTGGAGACGTGGAGATTGAGATAG TTGATAAATTGATTTCTGTACCGTATGTTGAAATGACAA TAAGGTTGATGGAACGCTTTGGAGTATCCGTAGAACATA GTGATAGTTGGGACAGGTTCTACATTCGAGGTGGTCAGA AATACAAATCTCCTGGAAAGGCATATGTAGAGGGGGACG CTTCTAGTGCTAGCTACTTCCTAGCAGGAGCCGCCGTCA CTGGTGGGACTGTGACTGTCAAGGGTTGTGGAACAAGCA GTTTACAGGGTGATGTAAAATTTGCCGAAGTTCTTGAGA AGATGGGTTGCAAGGTCACCTGGACAGAGAATAGTGTAA CTGTTACTGGACCACCCAGGGATTCATCTGGAAGGAAAC ATCTGCGTGCTATCGACGTCAACATGAACAAAATGCCAG ATGTTGCTATGACTCTTGCAGTTGTTGCCTTGTATGCAG ATGGGCCCACCGCCATCAGAGATGTGGCTAGCTGGAGAG TGAAGGAAACCGAACGGATGATTGCCATTTGCACAGAAC TGAGAAAGCTTGGGGCAACAGTTGAGGAAGGATCTGATT ACTGTGTGATCACTCCGCCTGAAAAGCTAAACCCCACCG CCATTGAAACTTATGACGATCACCGAATGGCCATGGCAT TCTCTCTTGCTGCCTGTGCAGATGTTCCCGTCACTATCC TTGATCCGGGATGCACCCGTAAAACCTTCCCGGACTACT TTGATGTTTTAGAAAAGTTCGCCAAGCATTGAGTAGCTA TATACGAGATCCTTAAATTGTACGCCGAAGGTTTTGATT TGAGTCTAATAGTAGATAAAAGGCTATAAATAAACTGGC TTTCTGCTTGAGTAATTATGAAATTCTTTGTATTATGTT TGTGAGATTTTAAGTAGCTTATAAATTACAATGTACTAA AGTCTAGAAATAAGTTATGTATCTTTTAAATCAATGAGA AATGCATACTTGAAAGGCTTGACCTTGTATTTGTGACCT 13 Amaranthus cDNA 1554 ATGGCTCAAGCTACTGCCATCAACAATGGTGTCCAAACT rudis Cont GGTCAATTGCACCATACTTTACCCAAAACCCACTTACCC ig AAATCTTCAAAAATTGTTAATTTTGGATCAAACTTGAGA ATTTCTCCAAAGTTCATGTCTTTAACCATTAAAAGAGTT GGTGGGCAATCATCAATTATTCCCAAGATTCAAGCTTCA GTTGCTGCTGCAGCTGAGAAGCCTTCATCTGTCCCAGAA ATTGTGTTACAACCCATCAAAGAGATCTCTGGTACCATT CAATTGCCTGGGTCAAAGTCTCTATCTAATCGAATCCTT 75 WO 2013/039990 PCT/US2012/054789 CTTTTAGCTGCTTTGTCTGAGGGCACAACAGTGGTCGAC AACTTGCTGTATAGTGATGATATTCTTTATATGTTGGAC GCTCTCAGAACTCTTGGTTTAAAAGTGGATGATGATAAT ACAGACAAAAGGGCAGTCGTGGAGGGTTGTGGTGGTCTG TTTCCTGTTGGTAAAGATGGAAAGGAAGAGATTCAACTT TTCCTTGGAAATGCAGGAACAGCGATGCGCCCATTGACA GCTGCGGTTGCCGTTGCTGGAGGAAATTCAAGCTATGTT CTTGACGGAGTACCAAGAATGAGGGAGCGCCCCATTGGG GATCTGGTAGCAGGTCTAAAGCAACTTGGTTCAGATGTT GACTGTTTTCTTGGCACAAATTGCCCTCCTGTTCGGGTC AATGCTAAAGGAGGCCTTCCAGGGGGCAAGGTCAAGCTC TCTGGATCGGTTAGTAGCCAATATTTAACTGCACTTCTG ATGGCTACTCCTTTGGGTCTTGGAGATGTGGAGATTGAG ATAGTTGATAAATTGATTTCCGTACCGTATGTTGAAATG ACAATAAGGTTGATGGAACGCTTTGGAGTATCTGTTGAA CATAGTGATAGTTGGGACAGGTTCTTCATCCGAGGTGGT CAGAAATACAAATCTCCTGGAAAGGCATATGTTGAGGGT GACGCTTCAAGTGCTAGCTACTTCCTAGCTGGAGCTGCC GTCACTGGGGGGACTGTGACTGTCAAGGGTTGTGGAACA AGCAGTTTACAGGGTGATGTAAAATTTGCCGAAGTTCTT GAGAAGATGGGTTGCAAGGTCACCTGGACAGACAATAGC GTAACTGTTACTGGACCACCCAGGGAATCATCTGGAAGG AAACATTTGCGCGCTATCGACGTCAACATGAATAAAATG CCAGATGTTGCTATGACTCTTGCAGTTGTTGCCTTGTAT GCAGATGGGCCCACCGCCATCAGAGATGTGGCTAGCTGG AGAGTGAAGGAAACCGAACGGATGATTGCCATTTGCACA GAACTGAGAAAGCTTGGGGCAACAGTTGAGGAAGGATCT GATTACTGTGTGATCACTCCGCCTGAAAAGCTGATACCC ACCGCCATCGAAACTTATGACGATCACCGAATGGCCATG GCATTCTCTCTTGCTGCCTGTGCTGATGTTCCCGTCACT ATCCTTGATCCGGGATGTACACGTAAAACCTTCCCGGAC TACTTTGATGTCTTAGAAAAGTTCGCCAAGCAT 14 Amaranthus Genom 2425 TGATACAAAGATTGCAACATTTGCAAGACCTTGCTGTTC rudis ic GGATTTAGAGCGAAATCTATTTGCCATTAATTTCGAATG GGTCGAATTTAGCCTTATCCTTATTCGTGATAACAAAGA GATTGCTTTGAAGTCCTTACGTTTGAAAATCCTGGACTT CACTGAATTAATGTAATTTTCCAGGATTTCTGTTACGTG CCATGAAATGGAATACTTTATTGATTATGTGCTAGGGAT AAATAAGCTTAAGAAGGCAATTTCCCAGGTCCTATTAAT GCTACCTACACTTCATATTAACCTTTCTGATATAGTTTT TCTTTTCTTTGCATGTATTGATTTAGCTATGTTCTTGAC GGAGTACCAAGAATGAGGGAGCGCCCCATTGGGGATCTG GTAGCAGGTCTAAAGCAACTTGGTTCAGATGTTGACTGT TTTCTTGGCACAAATTGCCCTCCTGTTCGGGTCAATGCT AAAGGAGGCCTTCCAGGGGGCAAGGTAATGTAATTAAAC TTTCTTTTTGTTTTGTTAGATTTTGTGTTTTACTCAATT TCTTGGTAGTACTTCTTTCCCTACCTAACTCCGACTTCT CAGATTGACCTTTTTTAAGAGGTGGGGAATAGTGTTTCT TAAGTGAGGAAAAGAGAAAGCCGGGGTATGAGCTTTAGC ATGACATCGTATGTATTTGATATTGATACTGCAAATCAA GTGGGAATCAAGCATAAAATAGCTTCAGAGGGATACATT TTCTTTTCTTGCATGAAGTTATACAGCATAAATGATCAG AGGTGTCTGCTGTGTATATGTGTAATAAGACTGTTATAG TTAGCAGGAATGCAGGAGATAAATTATGAAGATGGTGTT 76 WO 2013/039990 PCT/US2012/054789 GATGAATCTTAAAAGACAATTCAGAAACCAAAGTTTGAG TAGTAAGTGACTTTTGAGAGGTGTACTTCTCTCCCAAAT GAGCTATAAGCTCTAACAAAAGTCTCAATACTAATCAGA TGCCTCTCTCACGCTCCATCCCTTTATTTAGATTTCTTG ATTTCTTTTTTATAACTTTCCCAACTTATTCCCCGCTTT TCCTTCACGCTACCTTCTAACTGAAATAAAATGCAATTC TTACCTGGTTTCTTTATGGCTTGTTAATTTTAATAAGGA TCAAGTATAGTATGAAAGTAATTCTCTTTGGCATTAAGG CTTTTGCATTGTTGTTTGTCTAAGATCCCAATGGCAAGT TCACATAAGATATCTGTTGGTATATGTATAAAATAATTA GTCAGTTGAACAATTTTCTTTTTCTTGGCAAATAAACTC GTATGATACTTCACCGGGGGAGGGGGGGAGGGGGTTAGA TTTGGTACGGTAAGTATCCTGTGTATTATTTTTCTTCAG TTATTTTATTTAGTTGCTTTTTTGGGGTTACTTTTTTCT CCATCTAGGATCCTGTATGTTAATGTTTCTTCACTTATT TTATTTAGTTGCTTTTTTGGGGTTACATTTTTTTTCGAG GGGCTACTGAGTTCATAAGATAAGGGTCTTGTGTATTAA TATGCTCTTCACTTGGTGCTCGCTATTGGTGTAACTGTA ATTCAGGTGTCTTCTTCACTCTTAAGATAAGGATGATTT TATGAGAAATGTTTCCACATGCTTGGCACCAACTTGTTT ATGTGTAGTAGTAGAAGAAATTATGTATAACATGCATAC TCAGCATGGCAGTGACTAGTGAATAAGAATTGAAGAAAG GAGGTAAAGTTGCATGCAAGAAACCTATAAAAAGATGAT TCATTCAAAACCTTTTGCTATAGCCATGCTTACAAATTG ATCAAATTAGAACTTCAATTTCAAAGTTTGTTGTTAATG AGAAGTTAAGCATAGTTGTGATTTTCAATTTCACAGTCA TGAAGTAAGAAACTCTCTAATATTATCGTTTCCTTTTTG TAACCTGTTTGCAGGTCAAGCTCTCTGGATCGGTTAGTA GCCAATATTTAACTGCACTTCTGATGGCTACTCCTTTGG GTCTTGGAGATGTGGAGATTGAGATAGTTGATAAATTGA TTTCCGTACCGTATGTTGAAATGACAATAAGGTTGATGG AACGCTTTGGAGTATCTGTTGAACATAGTGATAGTTGGG ACAGGTTCTTCATCCGAGGTGGTCAGAAATACAAGTAAG TCTCTCATCTTACATTACATGTCCTTTTAACGTGTCTCC ATTAGTAGACTGAAAACGCATGTAAATGCATCAGATCTC CTGGAAAGGCATATGTTGAGGGTGACGCTTCAAGTGCTA GCTACTTCCTAGCTGGAGCTGCCGTCACTGGGGGGACTG TGACTGTCAAGGGTTGTGGAACAAGCAGTTTACAGGTAT AATGTTAACCCTTACCCTTGACATTGTTCTACTAAATTC TGGAGGACCCTTTCAATTCTGGGTGGGATAAGCACGACA ATTTGAC 15 Amaranthus Genom 2013 AAATGATGCAAATTAATTGGGATTACATTTTGAAGATTG rudis ic ATATTGAAATTGAGAGAGAGTTAAAATGTATGGATGAGA GGGTTGCAAATCAAATGAGACGGAGGGGGTAGATTAGCA AAATTAATAAGTTATTTGAAGATTGAATTTGTAAAATAA TTGATGAATCGGGCATTACATTTTGCTCATCCCATCCTA CACCAACCCCAAAACAATTCAACAACAAACTCTTTTTAC TACACCAACCCACTTTCTCTTTGCCCACCAAAACTTTGG TTTGGTAAGAACTAAGCCCTCTTCTTTCTCTCCCCCTTC TCCCTCTTAGAAGGCTAAAATCCACCTAACTTTTTCAGC CAAGAACACAAAGCGAAATTCAGAGATAAAGAGAAACAA TAATGGCTCAAGCTACTGCCATCAACAATGGTGTCCAAA CTGGTCAATTGCACCATACTTTACCCAAAACCCACTTAC CCAAATCTTCAAAAATTGTTAATTTTGGATCAAACTTGA 77 WO 2013/039990 PCT/US2012/054789 GAATTTCTCCAAAGTTCATGTCTTTAACCATTAAAAGAG TTGGTGGGCAATCATCAATTATTCCCAAGATTCAAGCTT CAGTTGCTGCTGCAGCTGAGAAGCCTTCATCTGTCCCAG AAATTGTGTTACAACCCATCAAAGAGATCTCTGGTACCA TTCAATTGCCTGGGTCAAAGTCTCTATCTAATCGAATCC TTCTTTTAGCTGCTTTGTCTGAGGTATTTATTTCTCAAC TGCTAAAACTTTCCAATCTCTATTTGATATTGGAATTTG TATTACATATTCCATCTTGTTGTAATTGCATTAGTAGAA AGTTATGTTTTGACCTTTGTTCATTTATTTGTTGAATTA GTATTGTTGAGAATTTGAATGTAATTATTTTTTTTCCAA TGTGAATTTAATCTGATTAAATCCACCTCTTATTTATGT TAAGTTGCAATGAGGTTTGCCAAACGGTTATCATTGAAG GATAAGTTTGCGTACTTCTGACCCTCCCAACTTCGCGTT GGTAGAGCCATTTAATGTTATTGGGGGTGATTAAAAAGA TGTATTTGTTTTGCCATTTGAAATAGTAGCGTTCGTGAT TCTGTTTTGGGTGTCTTTATAGATATGATATATGGGTTA TTCATGTAATGTGAAGGTTTATGTAATATCTTGGATGCA TGTCTGGTGTTGTTTGTTGTAAATGGTTGAATGTTGTTA TTTGGATACATTTTTTCATCCATTTTTTTTTCCCTTTTT ACTTGGAACTGGAAGAGGGAGGGTTATTGGGAGTAATTG AAAGGTTGTGAGTTTGAGACAGTGCATCCAAGACGAAGA ACTTGAGATAGATGTTGAAGGCTAAACCTTATCACTGCT TGAATTCATTATATATCTGAAAATTTTACTATATGCATC CGTTTTGCTAATAAAGTGTTTTTGGACTATCATGTTTTG TGATGCCCAAGAGGGTGATATTACTGTGATAAATGGAAA TATCATAATAACATCTATTGTTAAGTAGTTTTAGAGGCT TTTGATTGGTGCTTCGGCTTTGGTTTTACTTACCTCCTA GAGAAGATTGATTCTGGTTGTGCAATCTGAACATTATTT CATCATGGTATGAATATGGTTCAAAAACAAGGCTGCATC GCATTGGACACGTTGTGAAGATTTAAAAAAATCGAATTG ATATTTCTAGCATTGTAAAGGCTTAAATAAACTGTATTC CAGGCTATATTAGGGATCTCTCATGCTTTTGACCGATAT TAAGGTGTTACGATAACCGCATCACTCCTGCAATCGTGA CCGCATGTTTTCACTCTATTATGTGTTACAAGAGATTAG TGTTACATGAAGTGGATCCCCTGTGATTTTGTTCTAGGT GGACAGTGTTTTTGCCGAATTTTATGGCAGGATTTATAA AGAGATTGGATATTAGGGATTTGAATTTTTTAAAATGTT TCCCGTACTCCTATGGTTTTCTACACACAGTTTACCGAC TGTTTATTTGAATTTTTTGTTTGA 16 Amaranthus Genom 1530 CTGTTTATTTGAATTTTTTGTTTGAGAAAAGGCTTACAG rudis ic GCTTGCATATGTATATATGTATATTTATGTATTTGCTTT GTGGTCAAATGTGCTGCATGTTGTAATGAAAACTCTGCC CGGGGATGGCAGGCTTACATGCCAAAGAAAAAGATTGTG TTCCAAAACAGAAAATATCCCATCGGCATCAGCCTGCAA TTTTTTTGGGAATGGTATTAAATCTTGGAAATCTTCTCA ATTTGTTCAAACCATGAGGATTTTTCCGTAATCCAATAA TTAGCGCGTTGTTTCATTTGTAAAAATTACAATTTTTAA TCATATTTCTCTTTAGTGAAGCAACTGATTGGAAAACTT TGGTATCTGTCATGTTTCTTTCCAAGTTAAAGTGTTCCC ATGCATCATCTTCAAAAATCTTTCATAATGTTTTTGTAC AATATTTTCGATAGGAAGTTCATTCATGCCAAGGGTTAA CAATATGTCACTTGTGAATTTCTAAAATAGCAGAAAACA TATTGTGACCTGTAGAGTTCATCCCAAGGTATCCTCTGT GCGAGGGATGAAAAAAGCCTCTGGTAATTTATGCTACTA 78 WO 2013/039990 PCT/US2012/054789 TCCCAAGATAGTATTATTAGAAGTCATTTATAGCCGCGT AAGAGAGCCAAGGATCATTGTAGGCTTGTTCTATTTCCA TATCTTAATGTAGCACCCAAGTATTCCTCAGCAATATGA GTATTTTAAAGTCTTTCAAGTCATACATTATCTCTTGGC AATGAGTCGTTTCTGGATTTTGAATGCTGCCAGTCCACT AACTTACTGTAATGCAATACGTCATTATTCAGCTAGTTT CTTATTGGAAAAAAACCATAAAAATGGGAAAAGTTTGAG GTATATTTCTGTAATCCAACTTGAGGATTAGCTTTATCA CATAAAAGCTACATTGCAAGATCTATTATTAGTTTGAAT TTGCATCTTAAGTCTTGTTTTTCCTTAGTGATTTTTTCT TTAACTTGTTATTCGTTTCCTGAAGTTTCCAGTGTCATA ACTCCTAACCACAATCATGCTACAGGGCACAACAGTGGT CGACAACTTGCTGTATAGTGATGATATTCTTTATATGTT GGACGCTCTCAGAACTCTTGGTTTAAAAGTGGATGATGA TAATACAGACAAAAGGGCAGTCGTGGAGGGTTGTGGTGG TCTGTTTCCTGTTGGTAAAGATGGAAAGGAAGAGATTCA ACTTTTCCTTGGAAATGCAGGAACAGCGATGCGCCCATT GACAGCTGCGGTTGCCGTTGCTGGAGGAAATTCAAGGTT TGTCCAATTATATATTTTATGCGAGTGTGATTTTTGTAA TATTACTTTTTTTGTGTTAGTTTCAATCATGAAGCTGCT TATGCAGAAGCCGTACCCCTGAAATTTTCTTATTTTGTA TATATCAGTTGGTAATTGATGTAAGAGATTTTTCCGAGA GGAATAAAAATCAGGGGGGGCGAGTACCTATAAACTGTA ACCTCAAGAATATTAAACTATTGTTCTATCACATTAACT TTTGATCAA 17 Amaranthus Genom 1145 TTCTCATTACCACCGTTTATTACAATCTACCAAACGGGC rudis ic CGTTAAGGTTTTCTTAACTAGGGGTGTTTAGTTTGGAGG AAAGCTTTTTATTGGAAAACTGTTTTCTCCATATTCCTA TAATGACTTGACTGGATTTAGATTGGAAAATTAGGGTTG AAAACAATTTTTCCTTCCATTATAAGCTTATAATTTTAT AGTTAGATGAAAATCAAATTTCATTCACTTTCACTCCAT CTCCCTTGTTAGCATTATCGTTTTCCATTAAACAAAACA AAAGAAAAGTACTAATCATTAACGTTTACCTGGAAAATT ATTTCTAATGGTAATGTTCTCCGTCAGACCAAACACCTT CGGAATGAGGAAGCATTATGGATTAAAGAACCTTGTGCT TGGATTATTTTATTTGTCTATAAGATGCTTGTCTAGAGT GTGCTTGTATGTTTATTAACTTATCACGCCTCCTTTGCT ATCGAAGAAATATATATAAAAAAAAGAATTATTTCACCT GTAAGCGTACCCCAAATATCGACGCAAAATGCATGTCAC ATATGTGTAATGAATATGTTATGTGAATAAACAGTGGCT AGCTGGAGAGTGAAGGAAACCGAACGGATGATTGCCATT TGCACAGAACTGAGAAAGGTTAGCAGTCTTTTACATTCT TGAAGGTTGTAAATAGTTCTTGAGTAAAATATATTCAAT GTATAACTGATGTTCATTTGCATTCCTATCAATACTTCC AGCTTGGGGCAACAGTTGAGGAAGGATCTGATTACTGTG TGATCACTCCGCCTGAAAAGCTGATACCCACCGCCATCG AAACTTATGACGATCACCGAATGGCCATGGCATTCTCTC TTGCTGCCTGTGCTGATGTTCCCGTCACTATCCTTGATC CGGGATGTACACGTAAAACCTTCCCGGACTACTTTGATG TCTTAGAAAAGTTCGCCAAGCATTGAGTAGCCTATACGA GATCTATAAATTGTACGCCGAAGGTTTTGATTTGAGACT AATAGTAGATAAAAGGCTATTAAACTGGCTTTCTGCTCG AGTAATTATGAAATTCTTTGTATTATGTTTGTAAGATTT TAAGTAGCTTATAAATTACAATGTACTAAAGTCTAGAAA 79 WO 2013/039990 PCT/US2012/054789 TAAGTTATGTATGG 18 Amaranthus Genom 703 TCAAGTCAGTGGTCGGTAATGAAACGAATAATAAATGCT rudis ic AGAGAGAGAGAAAGTATGTGTACCGTAAATGGCATTGAG TGCGGGTATTTATAGAACAATAAATGACCTGGTTGGTTG TCCTAGGGGTATTTTAGTAATTTCACCCGTAGGTGGGTT GAGTCAAGACGTTGACTGGGCTGATTGGGCCCTTTGACT TAGCCCATAAATTTGGGGCTAGTTGACCCAATTACAATA ATGATATTTATAATATATAAAGTCCGTCTCTGTTATTTT CCAAACATCGAATAAAGTCAGCATCGACTCTCCATAAAA AGGATCCATTTCTTTTAGTTTGTCTAATTGGGCTCATAA AATACAAGGAACCCCTTTATATTTAGTAATTGATTGTGT TAAAGAAATGCACCTCAAGAAAATGTTTAACTTGATAGT TTGAGTCCTAATTTATTTTAGATATATTTTGCGGCTATT CTTTACATACATGAATTTGTTACGATAAAGTGTGGAGGC AATATACATCCTATTTATAAATGATTAAAATTAATCTCG GCCAAGATTAGGTATAGTCTCGCTCACGACTAATCCCAA TTCTTCATACAAACTTATGCCTTCTACGGAGTTTCACAA ATTCTTGTAAGAGACGGTCTCTTTGAAAGATCATNTCTA ATTGAACTGACCCATTAAAAAAAATATAGAGTAAAGTAG A 19 Amaranthus Genom 231 GACGGTGTCTCAGGAGACTAGCTGGCGGAGTTTAGCATC rudis ic AACCGATATTGGGCATTAGACTCGATCAAGACTTCATAA CCGAGACTCCGATTCTCTTCAAACCAATCATCTTATTTC AACCCATGTTAGTTTAAGTCATCAAATATCAACCGAATA AGTTTAGCTAATAAAAAGAAACGGAAGATAATATAATGC ATTATTGGAAGACAGAAATATACTTCCTCCGTTCCA 20 Amaranthus Genom 208 TAAGCTTGAACGATGAATAGTGTCAGTAACGAAAATGTA rudis ic GCAACTATTTCAGAACGGAGGAAGTAATTTGAAACAAAG AGAAAATTATTGTTCTTCAAGAAAAAGGTAGATAATAGT AATAAATGAAAAGAGAGAATGAATTGTATGGTTGAAATT GAGAGAGAGTTAAAATGTATGGATGAGATTTAAAGGAAG TGGTGGGCCATAG 21 Amaranthus Genom 94 AATCCAATACGTTATTTTAATCATTTATATATTGATTTA rudis ic TACACGTCTAAAAATTATAAAAAAATTAAAATAATGAAA ATATGCGATTAGACGA 22 Amaranthus Genom 40 ACTTGACTATATTTTGTCTTACACATTAGCCGCAATATA rudis ic T 23 Amaranthus Genom 3681 AAAGATGGAAAGGAAGAGATTCAACTTTTCCTTGGAAAT rudis ic GCAGGAACAGCGATGCGCCCATTGACAGCTGCGGTTGCC GTTGCTGGAGGAAATTCAAGGTTTGTCCAATTATATATT TTATGCGAGTGTGATTTTTGTAATATTACTTTTTTTTTT GTGCTAGTTTCAATCATGAAGCTGCTAATGCAGAAGTGT TGTAACCTCGCGAATATTAAACTATTGTGCTATCACATT AACTTTTGATCAAAGATGTACACTGTGTTTGTATAGTTT ATAGAGCTAAAGGGATGGAAGGGGTCGGGAGAGAAGAAG AGGAGAAAAGAAGAAGATCCTCCATATGTATACCAAGTG TTTGAACGGAAGGAAGAAGGAGGAAACTCTACACAATAT GGAGATGAAGTTTTTGGATAGAAGCCGCTTGAGAATGAG AGTTAATTCATGTGAAAGTCTATGAGAATGAGTTCACCT GCTTAATAATTTTAAGCTCTCAACTTCTCATCCTCTTTT CTTTGTCAAAAATATCATGTCTTCATGTGATAATTGCTT ACATAATCGATTATTTTGTAAAGCGGTTGTCTCTCTAAA TCTCTCCACTTACGAAAATAATTCTTCCTTGAAGGTTGA AGAAATCCCTTCATTTCCTTTTCCTCTATTTCTCCACCC 80 WO 2013/039990 PCT/US2012/054789 TTCCTACTTTGGTGTAGCATTTAGTATCCCTCCATTTCC ATGGCCTATAGTGTTAGATATATTCAAACTTAAGCATCT CATGTTTTATGTGGGTTCTAATTGTTATTTATATATGCA TTTCCAAGGATTCAAGGTAATTCGAACCAATCAAGCCCA AAACAGGATATGAATTCTTCAACCTAGTCTGAACTTGTA CATCTGAAACATACTAGTTGTAATTGAAATATACTCAAC TGTAATAGGACTCTCACCTTCATTGTAGGTTGCCACATA GCACGTATTGTCGATCCACCCATCCTTATTATTTGACAC ATCAAATAAAGGATCCACTCACGTGGAACTCCTACCCTA CAAAATAAACCATCTTCCTCATCTCATTTGTATTCACGT AGTTGCTTCCTCAATCCTACAAGTAAAAGGAGAATTGTG ATTCAACTTTTGGAGTTTGGACCTATTTTACTGTCAATC AACGAATATTAGGACAATCACATTGGTCGCTTGGCGCTT GAAACATTTGATTTCCTCAAAATCCTTTGCTTCCCCCAA CTTTTCATCCTTTTCTTTCCACATTAAAGTAGGTGCCCG AACCTCCATAGCCACAAACTTGGTTGTAGACGACATGCC AACCTTTCTACCTTTAATAAAGATAGGATTTGTAAAAGC CTTGCTCTTCTTAGATCCTTATCTTTCATAGACCATTGT CATCTTGTACATATCATCAAAAGACAAGTTGGTATGTAA CTCAGGCTTCTCGCACAAATTAACATCCTTCTCACCAAT GAACCTCCCTAGTAGAAATGCCTCTCGTACCTCAATATG ACAAGCCCTACCTCTCAAACTTCCACAAAGCTATAGATC TTCCATCCTGATGCAAGGAACTTCAACGCACATGTAAAT GTGGTTTGAATTTTAATGTTCAAAGGAAAAAACCTTTGT TTCATGTGCATCTTTATGTCAGCATAGCTATTAATCAGC TTCTTTTCTCTTGCACTAGCTATACTCTATACATTTAAG CCAACAAGAAGCTTGCTTCTTGAGCTCAAGTTTAACAAA CTTGAAAATTCAATTTTTGGGTGGAGTTCTTGTCGTAAA AACACTCCAAACTTCTCTCCTATTCAAGATAATCTTTTG GGTGTAAGGACATACTATCTAAATTTTCTACGTCATCTT GAAGCCATGGTCATCCACCTAGCAATCTGCTCAACTCTC GGTTCATGTTTATTCAACATCTGTGTGAATAGATTGATC AAGCTTGCCATCTGCTCAAGGATAGTTGAGTTATTCTCT TGTAATACTGGATTCCTCTCTTATGTTTTTTTAGTCATC CTACTATTTGCTAGCAACAAACAAT CTTACAAGAATATA AGAGGGGATTCTCTTGTATTATAAGGCACTACTCAGAAC CTAAGGAAGTAGTATGGGTGTCTTATTTTTGTCCTTGCC TCGTAGGACATAAAAGAGAGTTGTATTTGTGAATGATTC AACATAAACCAAAAGTATGTAGGCTCTTAGGTTATACCA TCTCATTAATATATGATGAAATCTTACGTATATTCCTTC ACATATATTTGTTTCTTTGGGGTCATTTATTGTAGCAGG TCATTGATATGGAATGCCTTAGTTATGGCATTATTGTAC GTGCACTGTCTCAGGAGAATAGATGGACTGTTTATGCTT TTTCGCTATTTGATGGTAATACAAAGATTGCAATATTTG CAAGACCTTGCTGTTCGGATATAGAGCAAAATCTATTAC CTCGATGCCATTAATTTTGAAGGGATCGAATGTATCCTT ATCCTTATTCATGATAACAAAGAGATTGCTTTGAAGTCC TTACGTTTGAAAATCCTGGACTTCACTGAATTAATGTAA ATTTCAGGTTTTCTGTTGCGTGCCATGAAATGGAATACT TTATTGCTTATGTGCTGGGAATAAGTAAGCTTAAGAAGG CAGTTTCCCAACTCCTATTAATGGCACCTACACTTTATA TTATCCTTTCTGATGTAGTTTTTCTTTTCCTTGCATGTG TTGATTTAGCTATGTTCTTGACGGAGTACCAAGAATGAG GGAGCGCCCCATTGGGGATTTGGTAGCAGGTTTGAAGCA 81 WO 2013/039990 PCT/US2012/054789 ACTTGGTTCAGATGTTGACTGTTTTCTTGGCACAAATTG CCCTCCTGTTCGGGTCAATGCTAAAGGAGGCCTACCAGG GGGCAAGGTACTGTAATTATATTTTCTTTTTGTTAAGTT AGATTTTGTGTTTTACTCCATCTAATTCGATGAATGATG ATTCATACGTCAATTTCTTGGTAGTACTTCCTTTCCCTA CCTAACTCTGACTTCTCTGATTGACCTTTTCTGTGACGT GGGGAATAGAGTTT TTAT TAAGTGAGGAAAAGAGAAACC CGGTGTATGAGCTTTAGCATGACAGAATATGTATTTGAT ATTTATACTGCAAATTAAGTTGGAATCAAGAATAAAATA GCTTCAGTTGGAGACAGTTTCTTTTCTTGCATGAAGTTT ATACAGCATAAATCATCAGAGGTGTCTGCTGTGTATGTG TAATAGACTGTTATAGTTAGCAGGAATGCAGTAGATAAA ATGAAGATGGTGTTGATAAAGCTTAACAGACAATTCAAA AAACAAAGTTTGAGTAGTAAGTAGACTTTTGAAAGGCGT GTTTCTCTCCCAAATGAGCTATAAGTTCTAACAAAAGTT TGAATACTTATCAGATGCCTCTCTCACGCTCTATCCCTT AATTCAGATTTCTTGATTTCTTTTTTATAACTTTCCCAA CTTATTTCCGCCTTTTTCTTCATGCCACCTTTTAACTGA AATAAAATGCAATTCCTACCTTGTTTCTTTAAGGCTTGT ACATTTTATTAAGGACTTAGTATGAAAGTAATTCTCTTT GCATTAAGGCTTTTGCATTGTTGTTTGTCTAAGATCCCA ATGGCAAGTCCACTTAAGATATCTGTTGGTATTAGGAAT GGTCACGTGTCCAGGACCCTGTTGGACCCGCCCCAGACC CGCCCCTTTTTTAAG 24 Amaranthus Genom 589 TGTGTAAAAAACGAAAACCCAGAGAGGTGAAACACCGGA rudis ic AGACACCTAACTTTTTCAGCTAAGCACACAAAGCGAAAT TCAGAGATAAAGAGAAACAATAATGGCTCAAGCTACTGC CATCAACAATGGTGTCCAAACTGGTCAATTGCACCATAC TTTACCCAAAACCCACTTACCCAAATCTTCAAAAATTGT TAATTTTGGATCAAACTTGAGAATTTCTCCAAAGTTCAT GTCTTTAACCATTAAAAGAGTTGGTGGGCAATCATCAAT TATTCCCAAGATTCAAGCTTCAGTTGCTGCTGCAGCTGA GAAGCCTTCATCTGTCCCAGAAATTGTGTTACAACCCAT CAAAGAGATCTCTGGTACCATTCAATTGCCTGGGTCAAA GTCTCTATCTAATCGAATCCTTCTTTTAGCTGCTTTGTC TGAGGTATTTATTTCTCAACTACTAAAACTTTCCAATCT CTATTTGATATTGGAATTTATATTATAGCTGCTTTGGAA TTTATAAAAACAGGTATGAGTATTAAATTAAATTATCAA GTTGAAGAAAGAGGATTTTTGAGGGGTTTTAATGGTGGT GGTG 25 Amaranthus Genom 479 GAAACTTATGACGATCACCGAATGGCCATGGCATTCTCT rudis ic CTTGCTGCCTGTGCTGATGTTCCCGTCACTATCCTTGAT CCGGGATGTACACGTAAAACCTTCCCGGACTACTTTGAT GTCTTAGAAAAGTTCGCCAAGCATTGAGTAGCCTATACG AGATCTATAAATTGTACGCCGAAGGTTTTGATTTGAGAC TAATAGTAGATAAAAGGCTATTAAACTGGCTTTCTGCTC GAGTAATTATGAAATTCTTTGTATTATGTTTGTAAGATT TTAAGTAGCTTATAAATTACAATGTACTAAAGTCTAGAA ATAAGTTATGTATGGGTTATGAATTATGATGCTGAAATC AATGAGAAATGCATACTTGAAAGGCTTGACCTTGAATTT GTGACCTAAAGAGTGGTAACTTTGGAGTTTCCAAGTCAT GTTGTTTATCTTAGTTTTTTTATATTGTTTATTCAAACT GTTTATTTTCA 26 Amaranthus Genom 473 CTCTAATATTATCGTTTCCTTTTTGTAACCTGTTTGCAG 82 WO 2013/039990 PCT/US2012/054789 rudis ic GTCAAGCTCTCTGGATCGGTTAGTAGCCAATATTTAACT GCACTTCTGATGGCTACTCCTTTGGGTCTTGGAGATGTG GAGATTGAGATAGTTGATAAATTGATTTCCGTACCGTAT GTTGAAATGACAATAAGGTTGATGGAACGCTTTGGAGTA TCTGTTGAACATAGTGATAGTTGGGACAGGTTCTTCATC CGAGGTGGTCAGAAATACAAGTAAGTCTCTCATCTTATA TTACATGTCCTTTTAACGTGTCTCCATTAGTAGACTGAA AACGCATGTAAATGCATCAGATCTCCTGGAAAGGCATAT GTTGAGGGTGACGCTTCAAGTGCTAGCTACTTCCTAGCT GGAGCTGCCGTCACTGGGGGGACTGTGACTGTCAAGGGT TGTGGAACAAGCAGTTTACAGGTATAATGTTAACCCTTA CCCTT 27 Amaranthus Genom 417 TCATATTGAGTTTTGGCGCCAACATAGACCTAATCAAAT rudis ic AATGAAAAATACAAACAACATCATATGGTTTCTTTTGTC TTTATGACTAGACACTCTTTATTATTCCTTGATTGGGAT CTTATTTTGAATGGTTGTTTAGCCTACACCTCATGTTCA GATTTTGTTCGTATACCAGACTTTTCTTGATTGCGATCT TATTTGTCCCCTGGATTTTGCATAGGGTGATGTAAAATT TGCCGAAGTTCTTGAGAAGATGGGTTGCACGGTCACCTG GACAGAGAATAGCGTAACTGTTACTGGACCACCCAGGGA ATCATCTGGAAGGAAACATTTGCGCGCTATCGACGTCAA CATGAATAAAATGCCAGATGTTGCTATGACTCTTGCAGT TGTTGCCTTGTATGCAGATGGGCCCAC 28 Amaranthus Genom 224 TTATCACGCCTCCTTTGCTATCGAAGAAATATATATAAA rudis ic AAAAAGAATTATTTCACCTGTAAGCGTACCCCAAATATC GACGCAAAATGCATGTCACATATGTGTAATGATTTTTTG TGTGAATAAACAGTGGCTAGCTGGAGAGTGAAGGAAACC GAACGGATGATTGCCATTTGCACAGAACTGAGAAAGGTT AGCAGCCTTTTACATTCTTGAAGGTTGTA 29 Amaranthus cDNA 2086 ACCACCATCACCATTAAAACCCCTCAAAAATCCTCTTTC rudis TTCAACTTGATAATTTAATTTAATACTCATACCTGTTTT TATAACCCGTAAATCCAGTGTAAAGCTTTGTTAAATTCA AGCAAAATTGCCAATACACTATGAAACTCTCGAAGATAA CTGTGTAAAACGAAACCCAGAGGTGAAACACCGGAAGAC AC CAAC TTTT TCAGCCAAGCAAACAAAGCAAAT TCAAAA AAGAGAAAGAATAATGGCTCAAGCTACTACCATCAACAA TGGTGTCCAAACTGGTCAATTGCACCATATTTTACCCAA AACCCACTTACCCAAATCTTCAAAAACTCTTAATTTTGG ATCAAACTTGAGAATTTCTCCAAAGTTCATGTCTTTGAC CAATAAAAGAGTTGGTGGGCAATCATCAATTGTTCCCAA GATTCAAGCTTCTGTTGCTGCTGCAGCTGAGAAGCCTTC ATCTGTCCCAGAAATTGTTTTACAACCCATCAAAGAGAT CTCTGGTACTGTTCAATTGCCTGGGTCAAAGTCTTTATC CAATCGAATCCTTCTTTTAGCTGCTTTGTCTGAGGGCAC AACAGTGGTCGACAACTTGCTGTATAGTGATGATATTCT TTATATGTTGGACGCTCTCAGAACTCTTGGTTTAAAAGT GGAGGATGATAATACAGCCAAAAGGGCAGTCGTGGAGGG TTGTGGTGGTCTGTTTCCTGTTGGTAAAGATGGAAAGGA AGAGATTCAACTTTTCCTTGGTAATGCAGGAACAGCGAT GCGCCCATTGACAGCTGCGGTTGCCGTTGCTGGAGGAAA TTCTAGTTATGTGCTTGATGGAGTGCCAAGAATGAGGGA GCGCCCCATTGGGGATCTGGTAGCAGGTCTAAAGCAACT TGGTTCAGATGTTGACTGTTTTCTTGGCACAAATTGCCC TCCTGTTCGGGTTAATGCTAAAGGAGGCCTTCCAGGGGG 83 WO 2013/039990 PCT/US2012/054789 CAAGGTCAAGCTCTCTGGATCGGTTAGTAGCCAATATTT AACTGCACTTCTCATGGCTACTCCTTTGGGTCTTGGAGA CGTGGAGATTGAGATAGTTGATAAATTGATTTCTGTACC GTATGTTGAAATGACAATAAGGTTGATGGAACGCTTTGG AGTATCTGTAGAACATAGTGATAGTTGGGACAGGTTCTA CATACGAGGTGGTCAAAAATACAAATCTCCTGGAAAGGC ATATGTTGAGGGTGACGCTTCAAGTGCTAGCTACTTCCT AGCTGGAGCCGCCGTCACTGGTGGGACTGTGACTGTCAA GGGTTGTGGAACAAGCAGTTTACAGGGTGATGTAAAATT TGCCGAAGTTCTTGAGAAGATGGGCTGCAAGGTCACCTG GACAGAGAATAGCGTAACTGTTACGGGACCACCCAGGGA TTCATCTGGAAGGAAACATCTGCGCGCTGTCGACGTCAA CATGAACAAAATGCCAGATGTTGCTATGACTCTTGCAGT AGTTGCCTTGTATGCTGATGGGCCCACTGCCATCAGAGA TGTGGCTAGCTGGAGAGTGAAGGAAACCGAACGGATGAT TGCCATTTGCACAGAACTGAGAAAGCTTGGGGCAACAGT TGAGGAAGGATCTGATTACTGTGTGATCACTCCGCCTGA AAAGCTAAATCCCACCGCCATCGAAACTTATGACGATCA CCGAATGGCCATGGCATTCTCTCTTGCTGCCTGTGCAGA TGTTCCCGTCACTATCCTTGATCCGGGATGCACCCGTAA AACCTTCCCGGACTACTTTGAAGTTTTAGAAAAGTTCGC CAAGCATTGAGTAACATATGGGTTCTTTAAATTGTACGC CAAAGGTTTTGATTTGAGACTAATAGTAGATAAAAGGCT ATAAACTGGCTTTATGCTTGAGTAATTATGAAATTCTTT GTATTATGTTTGTAAGATTTTAAGTAGCTTATAAATTAC AATGTACTAAAGTCTAGAAATAAGTTATGTATGGGTTAT GAATTATGATGCTGAAATCAATGAGAAATGCATACTTGA AAGGCGAAAAAAAAAAGAAAAAAAAACAAAACATGTCGG CCGCCTCGGTCTCTACTGA 30 Amaranthus cDNA 1960 CTTTGGTTTGGTAAGAACTTAGCCCTCTTCTTTCTCTCC rudis TCTCTCTCTCTCAGAAGGCTAAAATCCACCTAACTTTTT CAGCCAAGAAACAAAGCGAAATTCAGAGGTAAAGAGAAA GAATAATGGCTCAAGCTACTACCATCAACAATGGTGTCC AAACTGGTCAATTGCACCATACTTTACCCAAAACCCACT TACCCAAATCTTCAAAAACTGTTAATTTTGGATCAAACT TTAGAATTTCTCCAAAGTTCATGTCTTTAACCAATAAAA GAGTTGGTGGGCAATCATCAATTATTCCCAAGATTCAAG CTTCAGTTGCTGCTGCAGCTGAGAAACCTTCATCTGTCC CAGAAATTGTGTTACAACCCATCAAAGAGATCTCTGGTA CCATTCAATTGCCTGGGTCAAAGTCTCTATCTAATCGAA TCCTTCTTTTAGCTGCTTTGTCTCAGGGCACAACTGTGG TCGACAACTTGCTGTATAGTGATGATATTCTTTATATGT TGGACGCTCTCAGAACTCTTGGTTTAAAAGTGGAGGATG ATAATACAGACAAAAGGGCAGTCGTGGAGGGTTGTGGTG GTCTGTTTCCTGTTGGTAAAGATGGAAAGGAAGAGATTC AACTTTTCCTTGGAAATGCAGGAACAGCGATGCGCCCAT TGACAGCTGCGGTTGCCGTTGCTGGAGGAAATTCAAGCT ATGTTCTTGACGGAGTACCAAGAATGAGGGAGCGCCCCA TTGGGGATCTGGTAGCAGGTCTAAAGCAACTTGGTTCAG ATGTTGACTGTTTTCTTGGCACAAATTGCCCTCCTGTTC GGGTCAATGCTAAAGGAGGCCTTCCAGGGGGCAAGGTCA AGCTCTCTGGATCGGTTAGTAGCCAATATTTAACTGCAC TTCTGATGGCTACTCCTTTGGGTCTTGGAGATGTGGAGA TTGAGATAGTTGATAAATTGATTTCCGTACCGTATGTTG 84 WO 2013/039990 PCT/US2012/054789 AAATGACAATAAGGTTGATGGAACGCTTTGGAGTATCTG TTGAACATAGTGATAGTTGGGACAGGTTCTTCATCCGAG GTGGTCAGAAATACAAATCTCCTGGAAAGGCATATGTTG AGGGTGACGCTTCAAGTGCTAGCTACTTCCTAGCTGGAG CCGCCGTCACTGGGGGGACTGTGACTGTCAAGGGTTGTG GAACAAGCAGTTTACAGGGTGATGTAAAATTTGCCGAAG TTCTTGAGAAGATGGGTTGCAAGGTCACCTGGACAGACA ATAGCGTAACTGTTACTGGACCACCCAGGGAATCATCTG GAAGGAAACATTTGCGCGCTATCGACGTCAACATGAATA AAATGCCAGATGTTGCTATGACTCTTGCAGTTGTTGCCT TGTATGCAGATGGGCCCACCGCCATTAGAGATGTGGCTA GCTGGAGAGTGAAGGAAACCGAACGGATGATTGCCATTT GCACAGAACTGAGAAAGCTTGGGGCAACAGTTGAGGAAG GATCTGATTACTGTGTGATCACTCCGCCTGAAAAGCTGA TACCCACCGCCATCGAAACTTATGACGATCACCGAATGG CCATGGCATTCTCTCTTGCTGCCTGTGCTGATGTTCCCG TCACTATCCTTGATCCGGGATGTACACGTAAAACCTTCC CGGACTACTTTGATGTCTTAGAAAAGTTCGCCAAGCATT GAGTAGCCTATACGAGATCTATAAATTGTACGCCGAAGG TTTTGATTTGAGACTAATAGTAGATAAAAGGCTATTAAA CTGGCTTTCTGCTCGAGTAATTATGAAATTCTTTGTATT ATGTTTGTAAGATTTTAAGTAGCTTATAAATTACAATGT ACTAAAGTCTAGAAATAAGTTATGTATGGGTTATGAATT ATGATGCTGAAATCAATGAGAAATGCATACTTGAAAGGC GAAAAAAAAGAAAAAAAAACAAAACATGTCGGCCGCC TCGGTCTCTA 31 Amaranthus cDNA 939 CATCAACCTAGAATGCCCATATTTTACATGTTTAGCATT spinosus AACCCTAGAACATGAAACATAATGTGGGTGTTGAAATGC TAAATACAATAAAGTATCAAATTGTTTAGCAGGATTATC ATCACCTAAATTATCAGAACTCTCTAAAGGGTACCCTAA AGCTTGTTTAACCTCAAATAAATAATCATCAATCCAAAT TTTATCATTTTGATTAAGCTTTGAAGAGGGTAAACAAGA ACTTAATAATGGGAATTGTTTAAGGGACATTTGAGGACT ATTTAAGAATCTTTGAGCTAGTTTTGCATCATCTAATGG TGGTTTAAGGATGTATTTTCTAGGGGGTGCTTTTTCTTT GGGGATATTACTTTTTCTTTCAGCTAGTTCTTTTAGGAG TCTTTGAGGGCTAGTTTTTGGGAGTTCTTGAGGGTCTAT GGATGAAACAGCAAGAATTTGGTGATAATGGAAAGTGGG CTGGAGTTTTTTGATGGGAATTTGGAGGGAAAATGATGG GAAGGATGAAGTAAAGGAAACATCAGTGGTTTTTGAGAT GGGTTTAAAAGGGGATGAGAGGTCCATTGTAAGAAGAGA AATGAGAGGAAAAAGATGGAGTTTTGAGGATTGTTATGG GAGCTTTAATGGCGGATTGGACGGGACGCCATTGAAGTT GATGGAGAGTGAGAAAATGGAGGGTTTTAGAGGGTTCTA GTGAAGAATTGTGGAATTGGGAATTGAGGATAAGGTTGA TGGAACGCTTTGGAGTATCCGTAGAACATAGTGATAGTT GGGACAGGTTCTACATCCGAGGTGGTCAGAAATACAAAT CTCCTGGAAAGGCATATGTAGAGGGGGACGCTTCTAGTG CTAGCTACTTCCTAGCAGGAGCCGCCGTCACTGGTGGGA CTGTGACTGTCAAGGGTTGTGGAACAAGCAGTTTACAGG GTG 32 Amaranthus cDNA 381 TCCTGTTCGGGTCAATGCTAAAGGAGGCCTTCCAGGGGG spinosus CAAGGTCAAGCTCTCTGGATCGGTTAGTAGCCAATATTT AACTGCACTTCTCATGGCTACTCCTTTGGGGTCTTGGAG 85 WO 2013/039990 PCT/US2012/054789 ACGTGGAGATTGAGATAGTTGATAAATTGATTTCTGTAC CGTATGTTGAAATGACAATAAGGTTGATGGAACGCTTTG GAGTATCCGTAGAACATAGTGATAGTTGGGACAGGTTCT ACATCCGAGGTGGTCAGAAATACAAATCTCCTGGAAAGG CATATGTAGAGGGGGACGCTTCTAGTGCTAGCTACTTCC TAGCAGGAGCCGCCGTCACTGGTGGGACTGTGACTGTCA AGGGTTGTGGAACAAGCAGTTTACAGGGTG 33 Amaranthus cDNA 966 CAGCGATGCGCCCATTGACAGCTGCGGTTGCCGTTGCTG thunbergii GAGGAAATTCTAGTTATGTGCTTGATGGAGTGCCAAGAA TGAGGGAGCGCCCCATTGGGGATCTGGTAGCAGGTCTAA AGCAACTTGGTTCAGATGTTGACTGTTTTCTTGGCACAA ATTGCCCTCCTGTTCGGGTTAATGCTAAAGGAGGCCTTC CAGGGGGCAAGGTCAAGCTCTCTGGATCGGTTAGTAGCC AATATTTAACTGCACTTCTCATGGCTACTCCTTTGGGTC TTGGAGACGTGGAGATTGAGATAGTTGATAAATTGATTT CTGTACCGTATGTTGAAATGACAATAAGGTTGATGGAAC GCTTTGGAGTATCTGTAGAACATAGTGATAGTTGGGACA GGTTCTACATACGAGGTGGTCAAAAATACAAATCTCCTG GAAAGGCATATGTTGAGGGTGACGCTTCAAGTGCTAGCT ACTTCCTAGCTGGAGCCGCCGTCACTGGTGGGACTGTGA CTGTCAAGGGTTGTGGAACAAGCAGTTTACAGGGTGATG TAAAATTTGCCGAAGTTCTTGAGAAGATGGGCTGCAAGG TCACCTGGACAGAGAATAGCGTAACTGTTACGGGACCAC CCAGGGATTCATCTGGAAGGAAACATCTGCGCGCTGTCG ACGTCAACATGAACAAAATGCCAGATGTTGCTATGACTC TTGCAGTAGTTGCCTTGTATGCTGATGGGCCCACTGCCA TCAGAGATGTGGCTAGCTGGAGAGTGAAGGAAACCGAAC GGATGATTGCCATTTGCACAGAACTGAGAAAGCTTGGGG CAACAGTTGAGGAAGGATCTGATTACTGTGTGATCACTC CGCCTGAAAAGCTAAATCCCACCGCCATCGAAACTTATG ACGATCACCGAATGGCCATGGCATTCTCTCTTGCTGCCT GTGCAGATGTTCCCGTCACTATCCTTGATC 34 Amaranthus cDNA 484 CACCCAACTTTTTCAGCCAACAAACAACGCCAAATTCAG thunbergii AGAAAGAATAATGGCTCAAGCTACTACCATCAACAATGG TGTCCAAACTGGTCAATTGCACCATATTTTACCCAAAAC CCACTTACCCAAATCTTCAAAAACTCTTAATTTTGGATC AAACTTGAGAATTTCTCCAAAGTTCATGTCTTTGACCAA TAAAAGAGTTGGTGGGCAATCATCAATTGTTCCCAAGAT TCAAGCTTCTGTTGCTGCTGCAGCTGAGAAGCCTTCATC TGTCCCAGAAATTGTTTTACAACCCATCAAAGAGATCTC TGGTACTGTTCAATTGCCTGGGTCAAAGTCTTTATCCAA TCGAATCCTTCTTTTAGCTGCTTTGTCTGAGGGCACAAC AGTGGTCGACAACTTGCTGTATAGTGATGATATTCTTTA TATGTTGGACGCTCTCAGAACTCTTGGTTTAAAAGTGGA GGATGATAATACAGCC 35 Amaranthus cDNA 2329 CCCAGGAGCATCCAAATGTTTCATTAATAGCCTCTCGGC viridis CATCACAAGATCCTGGATCTTTTGGCCAAGATACTCCAG TCGCTCAAAACAGAACCTAGGATGTTCAAACTTGTATTT CGATGGATGTAGGAAACATAGCTGGAGCCCAAGTCCAAG CTCGATATTCCTTGCTTCAGTGATCTCTGGAAGTCGATC ATTCTTTGGCAAAGGATAACCCAATATTTTCATAACTTG TGGTCTGCAATCAAAATCCCAAATGTTTCCTCTGAACCG ATGCATGCCTGGAGGCACACAAGCTCTAAAAACCCTCGG ATGAGCAAAAAGAGCATCCTCGGGAGGCCTATAGGTAGC 86 WO 2013/039990 PCT/US2012/054789 TACATCTTGCCAATTGAGTTTTCTGCCTTCAAATTCCAC AGAAACATAATCAACATCTTCGAGCTGCCTTCTTTTCTT TGGTTGGCATTCTTCATCTTCTGGATCCATCCCAAACAC TTCAAATAGTACACGATAAACTTCCGGCATCCCATAACA CAAGTATATAGCACCAAACAAAGCCCAGAAAACAGACTT TGAAGCAGGCTCTTTCTCAGGGCGCCTCAATTTATCAAT ATCATCAAAAGGAAACACCAAATTATGCAGACTAGCAGC TTTAATCCACTTAGGTAAAAACCTCTTCCCTATCAAAGC AAACACTCTTTCCCTCATTGGTCCTGGAGACTCCCTTGG ATATCTCTGCAAGAAAAACTCCGCAAACCCTAATTCGAG CACGAATTGACCCAAAAACATCAACCTAGAATGCCCATA TTTTACATGTTTAGCATTAACCCTAGAACATGAAACATA ATGTGGGTGTTGAAATGCTAAATACAATAAAGTATCAAA TTGTTTAGCAGGATTATCATCACCTAAATTATCAGAACT CTCTAAAGGGTACCCTAAAGCTTGTTTAACCTCAAACAA ATAATCATCAATCCAAATTTTATCATTTTGATTAAGCTT TGAAGAGGGTAAACAAGAACTCAATAATGGGAATTGTTT AAGGGACATTTGAGGACTATTTAAGAATCTTTGAGCTAG TTTTGCGTCATCTAATGGTGGTTTAAGGATATATTTTCT AGGGGGTGCTTTTTTCTTTGGGGATATTATTTTTTCCTT TCAGCTAGTTCTTTTAGGAGTCTTTGAGGGCTAGTTTTA GGGAGTTCTTGAGGGTCTATGGATGAAACAGCTAGAATT TGGTGATAATGGAAAGTGGGTTGGAGTTTTTTGATGGGA ATTTGGAGAGAAAATGATGGGAAGGATGAAGTAAAGGAA ATATCAGTGGTTTTTGAGATGGGTTTAAAAGGGGATGAG AGGTCCATTGTAAGAAGAGAAATGAGAGGAAAAAAAATG GAGTTTTGAGGATTGTTATGTGAGCTTTAATGGCGGATT GGACGGGACGCCATTGAAGTTGATGGAGAGTGAGAAAAT GGAGGGTTTTTAGAGGGTTCGAGTGAAGAATTGTGGAAT TGGGAATTAAGGATAAGGTGATGGAACGCTTTGGAGTAT CTGTAGAACATAGTGATAGTTGGGACAGGTTCTACATAC GAGGTGGTCAAAAATACAAATCTCCTGGAAAGGCATATG TTGAGGGTGACGCTTCAAGTGCTAGCTACTTCCTAGCTG GAGCCGCCGTCACTGGTGGGACTGTGACTGTCAAGGGTT GTGGAACAAGCAGTTTACAGGGTGATGTAAAATTTGCCG AAGTTCTTGAGAAGATGGGCTGCAAGGTCACCTGGACAG AGAATAGCGTAACTGTTACGGGACCACCCAGGGATTCAT CTGGAAGGAAACATCTGCGCGCTGTCGACGTCAACATGA ACAAAATGCCAGATGTTGCTATGACTCTTGCAGTAGTTG CCTTGTATGCTGATGGGCCCACTGCCATCAGAGATGTGG CTAGCTGGAGAGTGAAGGAAACCGAACGGATGATTGCCA TTTGCACAGAACTGAGAAAGCTTGGGGCAACAGTTGAGG AAGGATCTGATTACTGTGTGATCACTCCGCCTGAAAAGC TAAATCCCACCGCCATCGAAACTTATGATGATCACCGAA TGGCCATGGCATTCTCTCTTGCTGCCTGTGCAGATGTTC CCGTCACTATCCTTGATCCGGGATGCACCCGTAAAACCT TCCCGGACTACTTTGAAGTTTTAGAAAAGTTCGCCAAGC ATTGAGTAACATATGGGTTCTTTAAATTGTACGCCAAGG TTTTGATTTGAGACTAATAGTAGATAAAAGGCTATAATT ATGAAATTCTTTGTATTATGTTTGTAAGATTTAAGTAGC TTATAAATTACAATGTACTAAAGTCTAG 36 Amaranthus cDNA 1746 ACCCGAACTTTTTCAGCCAACAAACAACGCTAAATTCAG viridis AGAAAGAATAATGGCTCAAGCTACTACCATCAACAATGG TGTCCAAACTGGTCAATTGCACCATATTTTACCCAAAAC 87 WO 2013/039990 PCT/US2012/054789 CCACTTACCCAAATCTTCAAAAACTCTTAATTTTGGATC AAACTTGAGAATTTCTCCAAAGTTCATGTCTTTGACCAA TAAAAGAGTTGGTGGGCAATCATCAATTGTTCCCAAGAT TCAAGCTTCTGTTGCTGCTGCAGCTGAGAAGCCTTCATC TGTCCCAGAAATTGTTTTACAACCCATCAAAGAGATCTC TGGTACTGTTCAATTGCCTGGGTCAAAGTCTTTATCCAA TCGAATCCTTCTTTTAGCTGCTTTGTCTGAGGGCACAAC AGTGGTCGACAACTTGCTGTATAGTGATGATATTCTTTA TATGTTGGACGCTCTCAGAACTCTTGGTTTAAAAGTGGA GGATGATAATACAGCCAAAAGGGCAGTCGTGGAGGGTTG TGGTGGTCTGTTTCCTGTTGGTAAAGATGGAAAGGAAGA GATTCAACTTTTCCTTGGTAATGCAGGAACAGCGATGCG CCCATTGACAGCTGCGGTTGCCGTTGCTGGAGGAAATTC TAGTTATGTGCTTGATGGAGTGCCAAGAATGAGGGAGCG CCCCATTGGGGATCTGGTAGCAGGTCTAAAGCAACTTGG TTCAGATGTTGACTGTTTTCTTGGCACAAATTGCCCTCC TGTTCGGGTTAATGCTAAAGGAGGCCTTCCAGGGGGCAA GGTCAAGCTCTCTGGATCGGTTAGTAGCCAATATTTAAC TGCACTTCTCATGGCTACTCCTTTGGGTCTTGGAGACGT GGAGATTGAGATAGTTGATAAATTGATTTCTGTACCGTA TGTTGAAATGACAATAAGGTTGATGGAACGCTTTGGAGT ATCTGTAGAACATAGTGATAGTTGGGACAGGTTCTACAT ACGAGGTGGTCAAAAATACAAATCTCCTGGAAAGGCATA TGTTGAGGGTGACGCTTCAAGTGCTAGCTACTTCCTAGC TGGAGCCGCCGTCACTGGTGGGACTGTGACTGTCAAGGG TTGTGGAACAAGCAGTTTACAGGGTGATGTAAAATTTGC CGAAGTTCTTGAGAAGATGGGCTGCAAGGTCACCTGGAC AGAGAATAGCGTAACTGTTACGGGACCACCCAGGGATTC ATCTGGAAGGAAACATCTGCGCGCTGTCGACGTCAACAT GAACAAAATGCCAGATGTTGCTATGACTCTTGCAGTAGT TGCCTTGTATGCTGATGGGCCCACTGCCATCAGAGATGT GGCTAGCTGGAGAGTGAAGGAAACCGAACGGATGATTGC CATTTGCACAGAACTGAGAAAGCTTGGGGCAACAGTTGA GGAAGGATCTGATTACTGTGTGATCACTCCGCCTGAAAA GCTAAATCCCACCGCCATCGAAACTTATGATGATCACCG AATGGCCATGGCATTCTCTCTTGCTGCCTGTGCAGATGT TCCCGTCACTATCCTTGATCCGGGATGCACCCGTAAAAC CTTCCCGGACTACTTTGAAGTTTTAGAAAAGTTCGCCAA GCATTGAGTAACATATGGGTTCTTTAAATTGTACGCCAA GGTTTTGATTTGAGACTAATAGTAGATAAAAGGCTATAA TTATGAAATTCTTTGTATTATGTTTGTAAGATTTAAGTA GCTTATAAATTACAATGTACTAAAGTCTAG 37 Ambrosia Genom 1340 GCGTCCAGTCGATGTTAACATGAACAAAATGCCAGATGT artemisiifo ic TGCCATGACTCTTGCAGTCGTTGCCCTTTATGCCGACGG lia TCCCACAGCCATTAGGGACGGTATGATTGAGCATTTTAC GTCTTTTTAATATTTTTTTCTCCCACAATTGGAATTTAC CACATATCCTTAAAATATAAAAAAATAGTTGTTTTAGAT TTTATATAAGACAGGTGCGCAGCGATGATCACATAAACC GACATGTATCCATATATAAAATTGTAGATGCAAAGACTT CCCCTCGGCTTTGTTAAATAATAGTTCATAATGACATCA TTTTCTCCCGGTATTTGGCAGTGGCTAGCTGGAGAGTAA AAGAAACCGAAAGGATGATTGCCATTTGCACAGAACTAA GAAAGGTACGAGTCAATATAACCATATTACTCTTAAACA GCTTTCAACCCATTATTGTTTAATGCTAAAAGACGTTTT 88 WO 2013/039990 PCT/US2012/054789 TGCATTTGTAACCTTGTTCAGTTGGGAGCAACAGTCGAA GAAGGACCCGATTATTGTGTGATCACTCCACCAGAGAAG TTGAACGTGACAGCCATCGACACATATGATGATCACAGA ATGGCCATGGCATTCTCCCTTGCTGCATGCGCAGACGTT CCTGTCACTATCAAGGACCCCGGCTGCACCCGTAAGACT TTCCCAGACTACTTTGAAGTTCTTGAGAGATTCACAAAG CATTAAACAGAATCTTTATGGCTGAAATGCTCCCTTCAC CTGTTGTCTTTCTTTACATATAATTGGTCTTTTTTTATG TTAAGGTTGTAGCTTTCTCTGAGATGGATCTGAGTGTAA TTTTAAATCTTTTGCAAAAATATGTTAGCAATGTATGTT TTTTTGATGCATATTAAATGTGCTATTATAATAAAAGTG TTTTTTTGACTCTTGAAGACATAAAGGTGTAACCTTGAT GCTCAAATTAGCATGTTGAACATGATAACTTTTAAGGGG TGTGACACAATGTTAAGCTTTTGAATCCCTCTTGCAAAA GTCCTATGTTTGACTTTGGCTCCTACCGGTATTATGTGC CCAGTGCAAGTGGTGTTTTACCTAATCCCGTTAGTTAGC ACTCAACATGGTATTGGTGAGGTCCTGTGAGTTTTCCGG TAACATGTTCTTGTCGTCTAAAAAATAGCACATGGAGGC TTCAAATTATTGATCTTTTTATGCTGAATAAGTGTATAT GTTTTGCTAACAGAAGTGGCAATGAGTTGTAAATCTTGA AAGATTAGAATGGCATAAAAGTGGGCTTGAACTCATGTG TTTCTCTTGAACCATTTTTATGCTGCTTACAATATAAGA TTAGTGGGGTCTAA 38 Ambrosia Genom 1264 CTATATAATAGTCTGTTTGGACTAAAAGTTGTAAATTTA artemisiifo ic AAAATATTTCAGGTCTCCTGGAAATGCTTATGTCGAAGG lia TGATGCTTCAAGTGCTAGTTACTTCCTTGCTGGTGCAGC AGTCACTGGTGGCACTATCACTGTAGAAGGATGTGGCAC AAGTAGTTTACAGGTACATTTTACCAAGAAGTTCATGTT TGTTAAGAAGTTCCCAACCAATTTAAACAATATCTCCAG AACGAGTGCATGTATTTTCCTTTTGATTACATACAAGTC ATGCTGTTTTTCTGGTTTTTCTTTGGGTTAAGGGTGATG TAAAATTTGCTGAGGTTTTGGAGAATATGGGTGCCAAAG TCACTTGGACTCAGAACAGTGTCACTGTTACTGGACCGC CAAGAATTCCGGAAGGAAGGAAACACTTGCGTCCCGTCG ATGTTAACATGAACAAAATGCCAGATGTTGCCATGACTC TTGCTGTTGTTGCCCTTTATGCTGGAACTACTGTGGTAG ACAATTTGTTGAACAGTGAGGATGTTCATCATATGCTTG TTGCTTTGGGAAAACTTGGATTACATGTGGAACATGACA GTGAAAAGAAACAAGCCATTGTAGAAGGCTGCGCTGGTC GGTTTCCGGTGGGGAAAGGGGAAGGTCAAGAAATTGAGC TTTTCCTTGGGAATGCTGGAACTGCAATGCGACCACTTA CTGCCGCTGTTACTGCTGCCGGTGGCAATTCAAGGTCTG TTCAATTTTGATCATTTTTACAATGTAATAATGCAAAAA AGTGACCATTAAATCAATTTACAATTCAACAGTTAAACT GAGATGTCAGCTTTTCAATAAATTCTTTTAGTTTTGTAA ACAAGTATGCTGCATTTTCCATGGAACCATCTGCTTATA TGCTAATGCACTTTGTTTTATATATAACTATCATGTTTT TGAGCTAATGCATGTTGTTACTTATATTTTAGCTACATA CTTGATGGCATACCTCGAATGAGAGAGAGACCTATTGAG GACTTGGTTACTGGTCTTAAGCAGCTCGGTGCAGACGTT GATTGCACTCTTGGCACAAATTGTCCCCCTGTTTATATA AATGGAAAGGGTGGTCTTCCTGGGGGGAAAGGTACGTCT CATATCAGTTCTGTTATGCTTTTGTGGTTTCATATTGTT GGATGAATTGTTTTGTAAGGTCGTCGTGGAACTGCTTCA 89 WO 2013/039990 PCT/US2012/054789 GAAATTGCTTTTCTAAGGTAGATACAGGAAGCCCCATAA GATACCACTATAAATG 39 Ambrosia Genom 910 TTTTTCTTCCACAATTGGAATTTACCACATATCCCTAAA artemisiifo ic ATATATAAAAAATATAGTTGTTTTACATTTTATACAAGA lia CAGGTGCGCAGCGATGATCATATAAACCAACATGTATCT ATATATAAAATTGTAGATGCAAAGACTTCCCGTCGGCTT TGGTAAATTAATGACATCATTTCTCCTGATATTTGGCAG TGGCTAGCTGGAGAGTAAAAGAAACCGAAAGGATGATTG CCATTTGCACAGAACTAAGAAAGGTACGAGTTATAACCA TATTACTCTTAAACAGCCTTCAACCCATTATTGTTTAAT ATGCTAAAAGACTCGTTTGCATTTGTAACATTTTCAGTT GGGAGCAACAGTCGAAGAGGGACCCGATTATTGTGTGAT CACTCCACCAGAGAAGTTGAACGTGACAGCCATCGACAC GTATGATGATCACAGAATGGCCATGGCATTCTCCCTTGC AGCATGCGCAGACGTTCCTGTCACTATCAAGGACCCCGG CTGCACCCGTAAGACTTTCCCAGACTACTTTGAAGTTCT TGAAAGATTCACAAAGCATTAAACAGAATCTTTATGGCT GAAATGCTCCCTTCACCTGTTGTCTTTCTTTACATATAA AATTGGTCCTTTTTTTATGTTAAGGTTGTAGCTTTCTCT GAGATGGATCTGAGTGTAATTTTAAATCTTTTGCAAAAA TATGTTAGCAATGTATGTTTTTTGATGCATATTAAATGT GCTATTATAATAAAAGTGTTTTTGACTCTTGAAGACATA AAGGTGTAACCTTGATGCCATGGGCGAACCTTTTAAGGG GCGGGAGGGAGCGCCCCCCTCGAATTTTCGCTCAGAAGT TGCGATTAAATGTCCTATGTTTGACTTCGGCTCTTACCG GTATTATGTGCCC 40 Ambrosia Genom 732 AATGAAGGGTGATGTGAAATTTGCGGAGGTTCTTGGACA artemisiifo ic AATGGGGGCTGAAGTAACATGGACCGAAAACTCTGTTAC lia GGTGAGGGGCCCACCGAGGGATGCTTCTGGAAGGAAACA TTTGCGTGCTGTAGATGTCAACATGAACAAAATGCCTGA TGTTGCCATGACTCTTGCCGTGGTTGCTCTATATGCAGA TGGTCCTACCGCCATTAGAGATGGTATTTTCCTCAATTC TGCATTTTACAAAAAAGTTTTACCAGCACAATCTAGATG CCCATTTTTTCGGCTTTTCTATTCATTATAATTTATATA CAGTTTGGTTGTTTATTAGCGTGCTCTCTTTTTGTTATT TTTCAGTNGCTAGCTGGAGAGTCAAAGAAACCGAAAGGA TGATTGCCATTTGCACAGAACTCAGAAAGGTAAAACAGC CCATTATCCGATCATAGCACTTATGAATAAGTCACTATG GGGTATTGTTCGCCTCAAAGAAGTTAAATAAAATAAAAA AGTTANNNNNNNNNNNNNNNTCCAAAAATCTCTCTCAAG CAGGCATCCTCCAAAATATTTAGAAGATTTAGATTATTA TATCGACATTACCGCATTAATATTTATAAAAAGATGGAC AAAATACTGTTATGGGTCAACCTAATCTCCATTGCCCAT ACTAAAACATGACATGTATTTTGACCCGTTACCCCGTCT TGTTACCTCTACTCATACTCATCTAACACT 41 Ambrosia Genom 278 TTGTTTATTAGCGTGTTTTCTTTTTGTTATTTTTCAGTT artemisiifo ic GCTAGCTGGAGAGTCAAAGAAACCGAAAGGATGATTGCC lia ATTTGCACAGAACTCAGAAAGGTAAAACAGCGCATTATC CGATCATAGCACTTATGAATAAGTCACTATATATGGGGT ATTGTTCACCTCAAAGAAGTTAAATAAAATAAAAAATTA TATGTTGAAACTCTCCAAAAATCCCTCTCAAGTAGACTT CCTCCAAAATTGGTCTAATCCCCCTGGCCCATACTAAAA CATGA 42 Ambrosia cDNAC 1503 ATGGCTNNAGCTACTACCATCAACAATGGTGTCCAAACT 90 WO 2013/039990 PCT/US2012/054789 trifida ontig GGTCAATTGCACCATACTTTACCCAAAACCCACTTACCC AAATCTTCAAAAACTGTTAATTTTGGATCAAACTTGAGA ATGTCTCCAAAATCACTTGCTGTTGCAGCTTCTGTTGCT ACCACAGAGAAGTCATCAGTTGAAGAGATTGTGTTGAAG CCCATTAAAGAGATTTCTGGAACTGTTAACTTACCTGGA TCCAAGTCTTTGTCTAATCGGATCCTTCTTTTAGCTGCT CTTGCTGAGGGCACAACAGTGGTCGACAACTTGCTGTAT AGTGATGATATTCTTTATATGTTGGACGCTCTCAGAACT CTTGGTTTAAAAGTGGAGGATGATAGTACAGCCAAAAGG GCAGTCGTAGAGGGTTGTGGTGGTCTGTTTCCTGTTGGT AAAGATGGAAAGGAAGAGATTCAACTTTTCCTTGGTAAT GCAGGAACAGCGATGCGCCCATTGACAGCTGCGGTTGCC GTTGCTGGAGGAAATTCAAGCTACATACTAGATGGTGTT CCCCGAATGAGAGAGAGACCAATCGGTGATTTAGTCACT GGTCTTAAACAACTTGGTGCAGATGTTGATTGTTTCCTT GGTACAAATTGCCCACCTGTTCGTGTAGCTGCCAATGGA GGCCTTCCTGGTGGAAAGGTCAAACTGTCGGGATCTATT AGTAGTCAATACTTGACGGCTCTGCTTATGGCAGCTCCG CTTGCACTGGGAGATGTAGAGATAGAAATTATAGATAAA TTAATATCTGTACCTTATGTAGAGATGACACTGAAATTG ATGGAACGGTTTGGTGTTTCTGTAGAACATAGCGATAGT TGGGACAAGTTTTATGTCCGAGGTGGTCAAAAGTACAAG TCACCTGGAAATGCTTACGTAGAAGGTGATGCTTCAAGC GCAAGTTACTTCTTAGCTGGTGCTGCCATTACCGGCGGC ACCGTTACGGTGGAAGGTTGTGGGACCAGCAGTTTACAG GGTGATGTGAAATTTGCGGAGGTTCTTGGACAAATGGGG GCTGAAGTAACATGGACCGAAAACTCTGTTACGGTGAAG GGCCCACCGAGGGATGCTTTTGGAAGGAAACATTTGCGT GCTGTAGATGTCAACATGAACAAAATGCCTGATGTTGCC ATGACTCTTGCCGTGGTTGCTCTATATGCAGATGGTCCT ACAGCCATTAGAGATGTTGCTAGTTGGAGAGTCAAAGAA ACCGAAAGGATGATTGCCATTTGCACAGAACTCAGAAAG TTGGGAGCGACAGTTGAAGAAGGGCCAGACTACTGTGTG ATCACTCCACCAGAGCGGTTGAATGTGGCAGCAATAGAC ACGTACGATGATCACAGGATGGCCATGGCTTTCTCCCTT GCCGCCTGTGCAGATGTTCCTGTCACCATCAAGGATCCT GCTTGCACTCGTAAGACGTTTCCAGATTACTTTGAAGTT CTTGAAAGATTCACAAAGCAT 43 Ambrosia Genom 1465 GTTTTGGTATGTTATCCAACCCTCCGTTTTTCCGCCTCT trifida ic AGTCAAAATGAGCTATTTCTAAATGACTTGTTTTTCTGA CACACTTCTATGATTCTTTTTAGCTGAATGAAGGGTGAT GTGAAATTTGCGGAGGTTCTTGGACAAATGGGGGCTGAA GTAACATGGACCGAAAACTCTGTTACGGTGAAGGGCCCA CCGAGGGATGCTTTTGGAAGGAAACATTTGCGTGCTGTA GATGTCAACATGAACAAAATGCCTGATGTTGCCATGACT CTTGCCGTGGTTGCTCTATATGCAGATGGTCCTACAGCC ATTAGAGATGGTACTTTCATCAATTCCCAACAACCCCTA GATGCCCATTTTTCGGATTTTCTATTCATTATAATTTAT ATGCAGTTTGGTTGTTAATTAGCGTGTGCTCTTTTTTGT TATTTTTCAGTTGCTAGTTGGAGAGTCAAAGAAACCGAA AGGATGATTGCCATTTGCACAGAACTCAGAAAGGTAAAA CAGCCCATCCTTCAAAATTGGTCTATTTAGAAGACTTAG ATTATTATATTGACATTAACGCATTAATATTTATAAAAA TATGGACAAAATATTGTTATGCGTCGACCTAATCTCCCT 91 WO 2013/039990 PCT/US2012/054789 GGCCCGTACTAGAACATGACAAGTTTTTTGACCCGTTAC GCCGTCTTGTTACCTCTGCTCATACTCATCTAACACTTT ACGGGTCAACAACTTTTTCAGTTGGGAGCGACAGTTGAA GAAGGGCCAGACTACTGTGTGATCACTCCACCAGAGCGG TTGAATGTGGCAGCAATAGACACGTACGATGATCACAGG ATGGCCATGGCTTTCTCCCTTGCCGCCTGTGCAGATGTT CCTGTCACCATCAAGGATCCTGCTTGCACTCGTAAGACG TTTCCAGATTACTTTGAAGTTCTTGAAAGATTCACAAAG CATTAAACAGAATCTTTATGGCTGAAATGCTCTCTTTAC CTGTTGTGTTTCACATATAATTGGTCCTTTTTTTTTATG TTAAGGTTGTAGCTTTCTCTGAGATGGATCTGAGTGTAA TTTTAAATCTTTTGCAAAAATATGTTAGCAATGTATGTT TTTTTTGATGCATATTAAATGTGCTATTATAATAAAAGT GTTTTTGATTCTTGAAGACATAAAGGTGTAACCTTGATG CTCAAATTATGTAACATAATGTTAAGCTTTTGAATCCCT CTTGCAAATGTCCCATGTTTGACTTCGGCTCTTACTGGT ATTATGTGCTCAGCGCAAGTGGTGTTTTACCTAATTCCG TTAGGTGGCACTCAACATGGTATTGGTGGGGTTCTGTGA GTTTTCCGGTAACATGTTCTCATTGTTTAGAGAAAAAAA ATGCACATGGAGGCTTCAAATTGTTCATCTATTTGTGTT GAATAATTTATATGTTGCTAGTAGAAGTGGCAATGAGTT GTAAATCTTGAAAGATTAGAAT 44 Ambrosia Genom 1022 TGTATATATATAAAATACATATACAATACCAAAACGCCT trifida ic AATTTCGCCTAATTTTCGCCTAGTCCCTAGGCTGGACCT CACCGCCTGCCTAGCGCCTAGCGCCTTTTGCAACCTTGT AAACATCTTATTAATAATGATACCTTTTGTTTCATCTTT ATGTAACCTTTTCTGGTCTTAATATGCAGGTCAAACTGT CGGGATCTATTAGTAGTCAATACTTGACGGCTCTGCTTA TGGCAGCTCCGCTTGCACTGGGAGATGTAGAGATAGAAA TTATAGATAAATTAATATCTGTACCTTATGTAGAGATGA CACTGAAATTGATGGAACGGTTTGGTGTTTCTGTAGAAC ATAGCGATAGTTGGGACAAGTTTTATGTCCGAGGTGGTC AAAAGTACAAGTAAGTCTGTTTTTTCATGAAAGTCATTT CCTTTTTGTGAAGATTGGTCGACGGGTTTATATGGTAAT TATCTGTTTCCAGGTCACCTGGAAATGCTTACGTAGAAG GTGATGCTTCAAGCGCAAGTTACTTCTTAGCTGGTGCTG CCATTACCGGCGGCACCGTTACGGTGGAAGGTTGTGGGA CCAGCAGTTTACAGGTGTGATCAGTAATCATATTCATCA GCTTCATAAAGCACATCCAAACACCCCAAACTATCTCTA CTTACATCTATGCATACGTCATATGATCTTACCCTTTCC GTTTGTTGTTTCTTTAAACTAGGGGGATGTAAAGTTTGC TGAGGTCCTCGGACAAATGGGTGCAGAAGTAACATGGAC AGAGAACTCAGTGACGGTGAAGGGCCCGCCAAGAAACGC TTCCGGAAGGGGACACTTGCGTCCAGTCGATGTTAACAT GAACAAAATGCCAGATGTTGCCATGACGCTTGCAGTCGT TGCCCTTTATGCCGACGGTCCCACAGCCATTAGAGACGG TATGATTGAGCATTTTATATCTTTTTTTTTAATATTTTT TTTCTCCCAGAAATCACAATTAGAATTTACCATACATTC TCAAAATA 45 Ambrosia Genom 697 ATATTAGATTTGTGTATTTCAAAAATCTTTTTAGAAAAT trifida ic AAACTAGTAATAATATATTCATGACAAAATAATATTATT GTGTGGGTTGGTAAGATGTTGGGGGTGGTTGGTGAAGGA AATGACACTCTAAAAAGCCGCCACCAAACTCCCCACCCT TTCAAAATCTTGCTTCTCCACGCAATAAATTCTTCATCT 92 WO 2013/039990 PCT/US2012/054789 TTTTCTCTGCAAATCACAAACAAACACAATGGCGATTCA CATTAACAACATATCCAACTTCACAACCAATCTCACCAA TACCCACAACCCCAAATCATTACCATCATCTTTTTTATC TTTTGGATCCAAATTCAACAACCCCATGAATCTTGCATC TCTTTCTTCCACCCAAACCATTAATAAAAGATCACTTGC TGTTGCAGCTTCTGTTGCTACCACAGAGAAGTCATCAGT TGAAGAGATTGTGTTGAAGCCCATTAAAGAGATTTCTGG AACTGTTAACTTACCTGGATCCAAGTCTTTGTCTAATCG GATCCTTCTTTTAGCTGCTCTTGCTGAGGTATGGTTATT GTTATTTGATTTGTTCATAATTGTGTTTTATGGTTATGT TTCTCAAAAGGGTCTTGTTCAAGATTTAATTTTGATAAG TTTTTTAGTGAATTTTGTGTAATTGAATTATTATTTTGA ATTGGGTGATAATATTGTATGATATGTGTGATAT 46 Ambrosia Genom 439 TATTAAATAAAATGATAAAAACTATACTGTTAAAAATAA trifida ic TACCCCAATAAGCGATATCAAAGATTATAAGCATTTAAA ACACCTTACCTGATTCTTTTGCCCGTTTTCTTTTAAGCT AAGTTGTAATTTTTTGGCGGTTTCACTCATTGGAGATTT GTATATTTGACCTCAGATTTCATCTTTTTATAATATCTT AAAAAGTTTTAATATGGTTTTTCAGCTACATACTAGATG GTGTTCCCCGAATGAGAGAGAGACCAATCGGTGATTTAG TCACTGGTCTTAAACAACTTGGTGCAGATGTTGATTGTT TCCTTGGTACAAATTGCCCACCTGTTCGTGTAGCTGCCA ATGGAGGCCTTCCTGGTGGAAAGGTAACCAACATTTGAT TGTTAATTACAGTGGCGAAGTTTGACCCGAAACTTCGGG GGGGTCGGAA 47 Ambrosia Genom 436 ATGCTACAGGGCACAACAGTGGTCGACAACTTGCTGTAT trifida ic AGTGATGATATTCTTTATATGTTGGACGCTCTCAGAACT CTTGGTTTAAAAGTGGAGGATGATAGTACAGCCAAAAGG GCAGTCGTAGAGGGTTGTGGTGGTCTGTTTCCTGTTGGT AAAGATGGAAAGGAAGAGATTCAACTTTTCCTTGGTAAT GCAGGAACAGCGATGCGCCCATTGACAGCTGCGGTTGCC GTTGCTGGAGGAAATTCAAGGTTTGTCCAATTATATTCT TTATGTGAGTGTTGTTTTTTGTGTTAGTCTCAATCATGA AGGTACTAATGCAGAAGCCGTACCCCTGAAATTTTCTTA TTTTGTATATATCAATTGGTAATTGATGTAAGATATTTT TCCGAGAGGAATAAAAAACAGGGGGATATGAAGAATATT AAAGTAT 48 Ambrosia Genom 404 GATCAGACCGGTCCACTCTTGTTTTAATTTGAGACAATT trifida ic TTGATGTTGAGTCATCCCACACCAACCCCAAAAAATTCA ACAACAAACTCTTATAATGATTCCCTCTACTCTACTAGA GTCTACACCAACCGACTTTCTCTTTGCCCACCAAAACTT TGGTTTGGTAAGAACTAAGCCCCCTTCTTTCCCTTCTCT CTCTTAAAAGCCTAAAATCCACCTAACTTTTTCAGCCAA GAACACAAAGCGAAATTCAGAGGTAAAGAGAAAGAATAA TGGCTNNAGCTACTACCATCAACAATGGTGTCCAAACTG GTCAATTGCACCATACTTTACCCAAAACCCACTTACCCA AATCTTCAAAAACTGTTAATTTTGGATCAAACTTGAGAA TGTCTCCAAAGTTC 49 Ambrosia Genom 1209 TGTTATGCCAGCCCTAATTTTATTCATGTAATCACTTCC trifida ic ATAACACACATCCAAAGTTCCCAACAACCCCTAGATGCC CATTTTTCGGATTTTCTATTCATTATAATTTATATACAG TTTGGTTGTTTATTAGCGTGTGCTCTTTTTTGTTATTTT TCAGTTGCTAGTTGGAGAGTCAAAGAAACCGAAAGGATG ATTGCCATTTGCACAGAACTCAGAAAGGTACGAGTCATA 93 WO 2013/039990 PCT/US2012/054789 ATAACCATATTACTCTTAAACAGCCTCCAACCGTTATTT TTTAACGCTAAAAGATTCTTTTTCATTTGGAACCTTTTC AGTTGGGAGCAACAGTCGAAGAAGGACCCGATTATTGTG TAATCACTCCACCAGAGAAGTTGAACGTGACAGCCATCG ACACGTATGATGATCACAGAATGGCCATGGCATTCTCCC TTGCTGCATGCGCAGACGTTCCTGTCACTATCAAGGACC CCGGCTGCACCCGTAAGACTTTCCCAGACTACTTTGAAG TTCTTGAAAGATTCACAAAGCATTAAACAGAATCTTTAT GGCTGAAATGCTCCCTTCACCTGTTGTCTTTCACATATA ATTGGTCCTTTTTTTTTATGTTAAGGTTGTAGCTTTCTC TGAGATGGATCTGAGTGTAATTTTAAATCTTTTGCAAAA ATATGTTAGCAATGTATGATTTTTGATGCATATTAAATG TGCTATTATAATAAAAGTGTTTTTGACTCTTGAAGACAT AAAGGTGTAACCTTGATGCTCAAATTAGCATGTCACACA TTATAACTTTCAAGGGGTGACATAATGTTAAGCTTTTGA ATCCCTCTTGCAAATGTCCTATATGTTTGAATTCGGCTA TTACCGGTATTATGTACTCAGTGCAAGTGGTATTTTACC TAATTCTGTTAGGTAGCACTCAACATGGTATTGGTGAGG TCCTGTGAGTTTTCTGGTAACATGTTCTCGTCGTTTAGA TAAAAAAAAATGCACATGGAGGCATCAAATTATTGATCT TTTTGTGTTGAATAGTTTATATGTTGCTAATAGAAGTGG CAATGAGTTGTAAATCTTGAAAGATTAGAATATATGGCA TAAAAGTGGGCTTGAACTCATGTGTTTCTCTTGAACCAT TTTTATGCTGCTTACAATATAAGATTAGTGGGGTCTAAA AGTCACCTTTACAGAATTAGAGGTCTAAATGAAGTCATA 50 Ambrosia Genom 984 TTATTTTCTTCAATTTCTTTGGTTGTTTTGTATTTTATT trifida ic AAAATTTAGTGGTCAAAACAACATTTTAGCACTGATCAA CCTTTTAATGGAATGATGCAGTGTGTCATGAACCGTAAT TTGATTTATAACGATAAAATAACAACAAATTTGTGTTTT TATGTTTACAGGTTAAGCTGTCAGGATCCATTAGTAGCC AATACCTTACTGCTTTGCTTATGGCTTCCCCCCTTGCCC TTGGAGATGTAGAAATTGAAATTATTGATAAATTAATTT CTATACCCTATGTTGAGATGACAATAAAATTGATGGAAC GGTTTGGTGTCTCAGTCGAACACAGTGATAGTTGGGACA GGTTCTTCATCAAAGGCGGTCAAAAGTACAAGTAAGTCT GTTTTTTCATGGAAGTCATTACTTTTTTTGTGAAGATTG GTCGACGGGTTTATATGGTAATTATCTGTTTCCAGGTCA CCTGGAAATGCTTACGTAGAAGGTGATGCTTCAAGCGCA AGTTACTTCTTAGCTGGTGCTGCCATTACCGGCGGCACC GTTACGGTGGAAGGTTGTGGGACAAGCAGTTTACAGGTG CATGATGACTTCTTTTTAGTTTAACTTAGAAATCTCTCT GACTTGGAAGTCAAGTCAATGGCTATAAACGGTTTTTTT CACGAAAGAAAATATCTTTGTATATTTGGTAATTTTTTA ATAAAATTATCACATCTTTTGTGAACTTTCTAAAGAAAT ATAAAGTTATGTTGTTTGACGTAACAAGTCGCGACTAAA TGTGTCAGTTTCAATTCAAAGTGTTAAACTTGTCAATCT AAAGTTGTACTTAACTGATAATGGGTAAAAACGTGTAAT ATTTAGCAATTATCTAAACGTGAAACGGGTGAAATACGT TGAGCATCTAAAAGGGCAAAAAAATCATCTAAAGTGCAT TCAAATGTTTACATCATCCTAGATTTAGAAATAAATCAT ATTGTTATG 51 Ambrosia Genom 980 ACTTAATGATTCAGCACTTAACCGTTCAGACCTCATAAT trifida ic GATTCAGCACTTTATCAACCAAACAACCCCTTAGTTAAT AGGAATCTGTACTGGTTTTGCATTTTACATAGCACTAAC 94 WO 2013/039990 PCT/US2012/054789 ATATGATGAAAAGATTGCTATTCGTCATCTATTTGGTAC AAACTTAGTTGTTCATAGTTGTTTCGACTTTCGTCTATG GAAATCATGAAAGCTTAAATCGATTTAAACCATTCACGG TTCGCCTCCATATTGCATGTCTGCTTATGTATTAACTGA ATGCATGTATTTTCATGATATGAATATTTGATTTGATCA TTGATTTGAAATAGTGTTTTTGTCATGAGCATATAGAGT TCGACCATTTGTTATAGTGTGAATTTGTCAAGCTATAAA TTCATCTACGCCACTTCAGCAAACTATTTCATTGACATT TTTAGCCTTCAGTTTATATTTAACAGATCTAAGTGAATT GATATTTTCAGGGGACTATTGTTGTAGACAACTTATTGA ATAGTGATGATGTTCATTATATGCTTGGAGCTTTGAGAG CTCTAGGGTTAAATGTTGAAGAAAATGGTGAGATCAAAA GAGCAACTGTGGAAGGGTGCGGTGGTGTGTTTCCGGTGG GTAAAGAAGCCAAGGATGAAATCCAGCTTTTTCTTGGAA ATGCCGGAACTGCTATGCGTTCGTTGACTGCTGCAGTTA CTGCTGCTGGTGGAAACTCAAGGTATTTTTAAATAGGAC ACTATTAATAAGGGTCTGCATGTGTCGGGTCGGGTTGTT GTATTAAATAAAATGATAAAAACTATACCGTTAAAAATA ATACCCTGATAAGCGATATCAAAGATTATAAGCATTTAA GAACACCTTACCTGATTCTTTTGCCCGTTTTCTTTTAAG CTAAGTTGTAAATTTTTGGTGGTTTCACTCATCGGAGAT TTGTATATTTGACCTCAGATTTCATCTTTTTATAATATC TTAAA 52 Ambrosia Genom 429 TGATCAGTAATCATATTCATCAGCTTCATAAAGCACATC trifida ic CAAACACCCTAAAATAAGTCTACATACATCTATGCATAC GTCATATGATCTTACCCTTTCCTTTTGTTGTTTCTTTAA ACAAGGGGGATGTAAAGTTTGCTGAGGTCCTTGGACAAA TGGGTGCAGAAGTAACCTGGACAGAGAACTCAGTGACAG TGAAGGGCCCGCCAAGAAACGCTTCCGGAAGGGGACACT TGCGTCCAGTCGATGTTAACATGAACAAAATGCCAGATG TTGCCATGACTCTTGCAGTCGTTGCCCTTTATGCCGACG GTCCCACAGCCATTAGAGACGGTATGATTGAGCATTTTA TATCTTTTTTTTAATATTTTTTTCTCCCAGAAATCACAA TTAGAGTTTACCAATCATTCTCAAAATAAAAATAAAAAA 53 Ambrosia Genom 234 AAAGAGATTTCTGGAACTGTTAACTTNNNNNGATCCAAG trifida ic TCTTTGTCTAATCGGATCCTTCTTTTAGTTGCTCTTGCT GAGGTATGGTTATTGTTAGTTGATTTGCTCATAATTGTT TTTAATGATTATGTTTCTGAAAAGGGTCTTGTTCAAGAT TTAATTTTGATAAGTTTTTGAGTGAATTTTGCATATTTG AAATTATTGTTTTGAATTGGGTTATAATATTGTATGATA 54 Ambrosia Genom 219 GTTTTAATATGGTTTTTCAGCTACATACTAGATGGTGTT trifida ic CCCCGAATGAGAGAGAGACCAATTGGCGATTTAGTCACT GGTCTTAAACAACTTGGTGCCGATGTTGATTGCTTCCTT GGTACAAATTGCCCACCTGTTCGTGTAGCTGCCAATGGA GGCCTTCCTGGTGGAAAGGTAACCAACATTTGATTGTTA ATTACAGTGGCGAAGCTTGACCCG 55 Ambrosia Genom 26 ACTAGTTTCGGGGGGTCGAAACCGTA trifida ic 56 Ambrosia cDNA 1721 AACAAACACAATGGCGATTCACATTAACAACATATCCAA trifida CTTCACAACCATCTCACCAATACCCACAACCCCAAATCA TTACCATCATCTTTTTTATCTTTTGGATCCAAATTCAAC AACCCCATGAATCTTGCATCTCTTTCTTGCAACCAAACC ATTAATAAAAGATCACTTGCTGTTGCAGCTTCTGTTGCT ACCACAGAGAAGTCCTCTGTTGAAGAGATTGTGTTGAAG 95 WO 2013/039990 PCT/US2012/054789 CCCATTAAAGAGATTTCTGGAACTGTTAACTTACCTGGA TCCAAGTCTTTGTCTAATCGGATCCTTCTTTTAGCTGCT CTTGCTGAGGGGACTACTGTTGTAGACAACTTATTGAAT AGTGACGATGTTCATTATATGCTTGGAGCTTTGAGAGCT CTAGGGTTAAACGTTGAAGAAAATGGTGAGATCAAAAGA GCAACTGTGGAAGGGTGCGGTGGTGTGTTTCCGGTGGGT AAAGAAGCTAAGGATGAAATCCAGCTTTTTCTCGGAAAT GCGGGAACTGCTATGCGTCCGTTGACTGCTGCAGTTACT GCTGCTGGTGGAAACTCAAGCTACATACTAGATGGTGTT CCCCGAATGAGAGAGAGACCAATCGGTGATTTAGTCACA GGTCTTAAACAACTTGGTGCCGATGTTGATTGCTTCCTT GGTACAAATTGCCCACCTGTTCGTGTAGCTGCCAATGGA GGCCTTCCTGGTGGAAAGGTCAAACTGTCGGGATCTATT AGTAGTCAATACTTGACGGCTCTGCTTATGGCAGCTCCG CTTGCACTGGGAGATGTAGAGATAGAAATTATAGATAAA TTAATATCTGTACCTTATGTAGAGATGACACTGAAATTG ATGGAACGGTTTGGTGTTTCTGTAGAACATAGCGATAGT TGGGACAAGTTTTATGTCCGAGGTGGTCAAAAGTACAAG TCACCTGGAAATGCTTACGTGGAAGGTGATGCTTCAAGC GCAAGTTACTTCTTAGCTGGTGCTGCCATTACCGGCGGC ACCGTTACGGTGGAAGGTTGTGGGACAAGCAGTTTACAG GGGGATGTAAAGTTTGCTGAGGTCCTCGGACAAATGGGT GCAGAAGTAACATGGACAGAGAACTCAGTGACGGTGAAG GGCCCGCCAAGAAACGCTTCCGGAAGGGGACACTTGCGT CCAGTCGATGTTAACATGAACAAAATGCCAGATGTTGCC ATGACGCTTGCAGTCGTTGCCCTTTATGCCGACGGTCCC ACAGCCATTAGAGACGTGGCTAGCTGGAGAGTAAAAGAA ACCGAAAGGATGATTGCTATTTGCACAGAACTAAGAAAG TTGGGAGCAACAGTCGAAGAAGGACCCGATTATTGTGTG ATCACTCCACCAGAGAAGTTGAACGTGACAGCCATCGAC ACGTATGATGATCACAGAATGGCCATGGCATTCTCCCTT GCTGCATGCGCAGACGTTCCTGTCACTATCAAGGACCCC GGCTGCACGCGTAAGACCTTCCCAGACTACTTTGAAGTT CTTGAAAGATTCACAAAGCATTAAACAGAATCTTTATGG CTGAAATGCTCCCTTCACCTGTTGTCTTTCTTTACGTAT AATTGGTCCTTTTTTTTATGTTAAGGTTGTAGCTTTCTC TGAGATGGATCTGAGTGTAATTTTAAATCTTTTGCAAAA ATATGTTAGCAATGTATGATTTTTGATGCATATTAAATG TGCTA 57 Ambrosia cDNA 1689 TACTACTACGTGTTCTTAGGTGAAAACTCACACACAATG trifida GCAGCTCACGTTAGCAACGTTGCTCATATCTCCAAACAT CCAATTCAATCTTTAATAATCTTTCCAAATCCCAAACCC CTTCTTCCAAGTCCTCGCCTTTCTTATCTTTTGGATCCA AATACAAAACCCCATTTACCCATTTCTCTTATTCATCTA ATAACAGAAAGCTTTTCACTGTTTCTGCTTCTGTTGCTG CCACGTCAGCAATACCGGAGATAGTGTTGCAACCCATTA AAGAGATTTCGGGTACTGTTAATTTGCCTGGCTCTAAGT CTCTGTCTAATCGGATTCTTCTTCTTGCTGCTCTTTCTC AGGGAACAACCATTGTTGACAACTTACTTAACAGTGACG ATGTCCATTACATGCTTGGGGCTCTAAGAACTCTAGGTT TACGTGTTGAGGAAGATGGTGCAATTAAAAGGGCAGTTG TGGAAGGTTGTGGTGGTGTTTTTCCGGTGGGTAGAGAAG CTAAAGATGAAATACAGCTTTTTCTTGGTAACGCAGGAA CTGCTATGCGCCCTTTGACTGCTGCAGTTACCGCTGCTG 96 WO 2013/039990 PCT/US2012/054789 GTGGTAATTCAAGCTACATACTAGATGGAGTTCCTCGAA TGAGAGAGAGACCAATAGGTGACTTAGTCACAGGTCTTA AGCAGCTTGGTGCAGATGTCGACTGTTTCCTCGGGACAA ACTGCCCGCCTGTGCGTGTAGTTGGAGGTGGGGGCCTTC CTGGCGGAAAGGTTAAGCTGTCAGGATCCATTAGTAGCC AATACCTTACTGCTTTGCTTATGGCTTCCCCCCTTGCCC TCGGAGACGTAGAAATTGAAATTATTGATAAATTAATTT CTATACCCTATGTTGAGATGACAATAAAATTGATGGAAC GGTTTGGTGTCTCGGTCGAACACAGTGATAGTTGGGACA GGTTCTTCATCAAAGGCGGTCAAAAGTACAAGTCGCCCG GAAACGCGTACGTAGAGGGTGATGCTTCAAGTGCAAGTT ACTTCTTGGCTGGTGCTGCTATAACTGGTGGCACCATCA CTGTTGAAGGTTGTGGAACAAGTAGCTTACAGGGTGATG TGAAATTTGCGGAGGTTCTTGGACAAATGGGGGCTGAAG TAACATGGACCGAAAACTCTGTTACGGTGAAGGGCCCAC CGAGGGATGCTTCTGGAAGGAAACATTTGCGTGCTGTAG ATGTCAACATGAACAAAATGCCTGATGTTGCCATGACTC TTGCCGTGGTTGCTCTATATGCAGATGGTCCTACAGCCA TTAGAGATGTTGCTAGTTGGAGAGTCAAAGAAACCGAAA GGATGATTGCCATTTGCACAGAACTCAGAAAGTTGGGAG CGACAGTTGAAGAAGGGCCTGACTACTGTGTGATCACTC CACCAGAGCGGTTGAATGTGGCAGCAATAGACACGTATG ATGATCACAGGATGGCCATGGCTTTCTCCCTTGCCGCCT GTGCGGATGTTCCTGTCACCATCAAGGATCCTGCTTGCA CTCGTAAGACGTTTCCGGATTACTTTGAAGTTCTTCAGA GATTCACCAAGCATTGATGTTTTCAATAGAGTTTTTGTT TTATTTGTAACATGCCAAATATGTGATTTTTGGAATATT TTATTTGTAATTCTTTGGAAGTATGAATGATAAGATTTG AGTGTGTATTTT 58 Chenopodium cDNA 1432 TTTAAGAACTCTTGGGCTAAATGTAGAGGATGATAAGAC album AGCCAAAAGGGCAATTGTGGAGGGTTGTGGTGGTCTATT TCCTGCTGGTAAAGAGGGAGGGGGTGAAGTTGAACTTTT CCTTGGAAATGCAGGAACAGCAATGCGTCCATTGACAGC CGCAGTTGCTGTTGCCGGAGGAAAGTCTAGTTATGTACT TGATGGAGTGCCAAGAATGAGGGAGCGACCCATTGGGGA TTTGGTAGCTGGTCTGAAGCAACTTGGTGCTGATGTTGA CTGTTTTCTTGGCACGGATTGTCCTCCTGTCCGGGTTAA TGCTAATGGGGGCCTTCCAGGGGGAAAGGTCAAGCTCTC AGGATCAGTTAGTAGCCAATATTTGACTGCGCTGCTCAT GGCAACACCTTTAGGTCTTGGAGACGTTGAAGTTGAAAT CATTGATAAATTGATTTCTGTACCTTATGTGGAGATGAC AATAAAGTTGATGGAACGTTTTGGTGTGTCAGTAGAGCA TAGTGCTAACTGGGATAGGTTCTTGATCCGAGGTGGTCA GAAGTACAAATCTCCTGGAAATGCATATGTCGAGGGTGA TGCTTCAAGTGCTAGTTACTTCCTAGCAGGGGCTGCAGT CACTGGTGGAACTGTGACTGTTGAGGGTTGTGGAACAAG CAGTTTACAGGGTGATGTAAAATTTGCCGAAGTTCTTGA GAAAATGGGTTGCAAGGTTACCTGGACAGAGAACAGTGT CACTGTAACTGGACCGCCCAGGGATTCATCTGGAAGAAA ACACTTGCGCGCCGTTGATGTCAACATGAACAAAATGCC AGATGTCGCTATGACTCTTGCTGTTGTTGCCCTTTATGC AGATGGGCCCACTGCCATCAGAGACGTTGCTAGCTGGAG AGTGAAGGAAACAGAACGGATGATTGCCATTTGCACAGA ACTCAGAAAGCTTGGGGCAACCGTTGAGGAAGGACCTGA 97 WO 2013/039990 PCT/US2012/054789 TTACTGTGTGATCACTCCACCTGAGAAACTAAACGTGAC AGCCATTGACACATATGATGATCACCGAATGGCCATGGC ATTCTCTCTTGCTGCCTGTGCTGATGTTCCTGTCACCAT CAACGACCCAGGGTGCACTCGCAAAACCTTCCCAGACTA CTTTGACGTTTTGGAAAGGTTTGCCAAGCACTGAGTTGC CATCTATTGGTTATCTAGAGCATACAAATTTGAATCAAG ATTAAAATGCTTTCAGCTTCAGCTTTCGCCGCATTCTTT GTATCATGTTTGTAAGATTTTAGTTTATACAGTGTATTA ATTTTGTATCAGGCCAGTTAGAAATAATATTCTTGAAAA GATGAACTATGAGAATGTGATTTAGAAACTAGTATTGGG GTCTGAACTCTACAGCAATAACTGCAGAGTTTTGACACC ATATTTTGGTAATGTGAGTTCCATACTG 59 Conyza Genom 15055 TCAACAAAATCTTTCACCATGTCAAACAACGAAAACCAA canadensis ic AGTAACGACCTTTGGAATCACTTTCAAGAAAACCCGATG CTGAGTATGCCCCTGATGCCGCCTATACCGGTTATATCA TCAGCTAACCAAGGCCAAACAAGCCATGTTTCAGGCTCA TCCAACCCGACCCCAATGGGGAGACCAGTTCCGACGGGT TTGTCGCAATACGACCTAGAAGCACATATGAGTTATCGC CAACACTTGCAACAGAACTATGCAAGCTCGTTTTATGCA CCACCGGCGGCACCGGGGCCACAACCGGGTCCTAGCCAC GACCCGGAAGAGGACGAGGATGACCAGACCGCCGACGGC GAGTAGTTTTTTTAAAATACTCGTAATGTTTTATTTTTC TTTGCAATGTTTTATTTTTAAGTGTGTTATGTGTTTTAT TTTTAGTGGTAATGTTTAATTGTAATTTTTTTTTAATTT AGTTGTAATGGTTAATTTTTAATAAAATTAAGTAGTTTT TTAAGTTTGTGTGTAAATAAATATAAAATAAAATAAAAA AAATAAAAAGTGTGGAAGAGGGGTTATAGGGAGTGATTG TGGAAGAGGTGGATGAAGAAAGAGAAAAGCTGACGTGAC AGTGTGGAAGAGGGTAAGGATGAGGTGCTATAGGGAGAG GTCTTATTGAGTTATAATGATGTCAATGGCTTAATAACT TAATGACATTTTGGTGATGCGTAAGACCTTAAGACCAGA AAGTCTAAGTTTGAATCTTATAAAATAGGTTTTTTTCTA TTTTCCAAATTTATTGAGTTTTCTCATGAGTTCATGTAT GAGCATTATTGCATAGTGAAAATATGGTCAGATGGTTTC ATCGATGACAAGCTAATTTTTAAGAAAGATATATTACTT TTCTTTTTAACTTGGGAAAATCATAAAAGTGAAATCATC GTTTTAACTTTTTACGAGCATGGTACTCGCGTAATGCAG CGGCGGTGGTATAGAAGACGGTCTAATGGTGGCAGTGTC AAGTGGTGTAGGTCTATGTGCACCGAAACTCCAAACTGA CATAGCCGTACCCATTTCCGAAACTCCATGGAAACGTTT TCTCTTACGAAACACGTATGAAACATTCCCTAAAATTTT CTATAGATTAAACGTTTCTTTGAAGTTTCCATACGGTTT CTAATTAATATCAAGGTTTTAAAGGACTTTTTCGAATCC CCAAACCCAAACATGTTATATTATATACAATTTGATCAA CATTAAATTTTTTATATTACAAAGCCATTATTAAACACT AAACATTCAATGAGTGATCACTAATCAAACATGTATTAT AAAGTTCTACATATATAATTATACATAATCTCTCAAGTC TCAAATCTCCTTTATGAAAAAATTGATATAATTTATATT TGTATATTTTTTTTATTGTTGTACCCGTATCCTGGATTT TTTAGTTTTACTGTTCCCCGTTCCCGTATTGTTCCCGTA CCCTTTTCCCGTACCTGTTTCGGTGCTACATAGGTGTAG GTTGATGTAATTGTGATAGTGAAAAGTTTTAGAAGATAA GAGTTTAAAGTGTTAAGTATTAAAATAAGGGTTTATGGT GTAAATTAATTCATTAAGGGGAAAATTTATAAAACTATT 98 WO 2013/039990 PCT/US2012/054789 TCTATAGTGGGTTTTTATTAAGAGACAATTTAGTAATTT TATATGTGACATATGAGTAACTATTTTTATTTTGAGAGG GGTGCATAATTTTTATTCGAAGAGTACGGATAAAAGTCA ATAAATTACGAGCAGTGAAGTATCCCAGACACCCCTTGC AAGGTAATTTTTTAAAATTTTATTCATGGAGGTTTGGTA GGAAGTGGTGGTGGTGGTGGTTGGTATGAAATTTTGTTT TTGACCTTCTTCAAACATCCACCTACTACTGACCCCTCC CTTCAAACCCAACCCAAAATCCAAATCATTAAATCCTTC AAACCCACTGTGTGTTTTGTGTGAAATTTCACACACAAC AAACAATGGCAGCTACTCACATTAACACCACCAACATTG CCCACAATCTCCAAGCTACCACCAGTCTTTCCAAAACCC AAACCCCATCAATAAAGTCACAACCTTTTTTATCTTTTG GGCCAAAACACAAAAACCCGATTGCCCATTTCTCTGTTT CTTCTAATAATAATAGAAATCTTGGAAAAAAATGTTTAA TAGTTTCTGCCGTTGCCACCACCGAGAAACCGTCAACGG TGCCGGAAATTGTGTTACAACCCATTAAAGAAATCTCGG GTACGGTTAATTTACCCGGGTCCAAGTCGTTGTCTAATC GGATCCTCCTCCTTGCTGCGCTTGCTGAGGTATAGTTTA ATTTGGTAATAATGTTTGACCTTTAAAATTTGACATTTG GGCTACATGATTGATATGGGTCTTGAATGAATTGTGTTA TAAAATTTGGGAAGTTAAATGTTAATAATAGTTTAATCC TTTAGAAATTATGAAGTAATGGTTTTAGACCCTGAATTT TTTTTTATTGCATAGGTTAGTCCCTTAGCTAGTTAGCTT TTGGTTGACATCTTAGAAAAACCAGTACAGTTTTTATAT TTTAGTCCTTAAGCTTCAATTTTTTGCAATGTATTGCCA TTTGAAATGATCTAGTAAAATGTTCAAAATCAATGAATT GGCGGTTTAAAGATATAATGCTTGGATCAATTGTTATGT AAAGTGTGCTAGGCGGTCAAAAGCGAATCTTGGATCAAG GAAGTCGTAGAATACTATTGATTTCATATTATTGATTTC TTATTATGCATATTTGACATGTGCTTCTAACATCATGGC ATTTGGGATTTATTTCTATATATAAAGCATGACTGTATG GTTATAAAGTTCAAAACTTGTATGGTATAAATATACTCT TCTTACTTCTTAGCAGGAATGTGTTGACTTATAAGCTGA AAACTTTTATAACTCCAATTGTGTGTAGTAATACTTGAA AGTGGCTGAGTTCCTAGGACAGTATTACATGCGAACACT ACAACGTGTTACTAAATTTGAGATAGGTATGATTTGGTT TTGTTGGATACAAAGTCTAGGTCAGTTAACATAGCCAGT TGAGGACGATAGCTTTCTTGTCTTATTTCCTTTTTATAG AGGGTTTGTGTTTCGTGATGGTAATATTGAGTACCACCA TATAGTTCACAAGTCATATAATAAAATCAGAGCAACATT CGAGGAGTCGCCTATATGCATATTATTGCACCATGCTAA AATCCAAGGGCATATTTTGATGCCAATTTGTAATTTATT TCTCAGGGAACGACCATTGTTGACAACTTACTCAACAGT GATGATGTTCATTACATGCTTGGAGCTTTAAGAACTCTA GGGCTAAACGTTGAGGAGGATGTTGCAATTAAAAGGGCA ATTGTGGAAGGTTGTGGCGGTGTGTTTCCTGTGGGTAAA GAAGCTAAAGATGACATACAGCTTTTTCTTGGGAATGCA GGAACTGCTATGCGTCCATTGACTGCCGCAGTTACTGCT GCTGGTGGTAATTCAAGGTATTTGGACGTTGTCATTGAC TCATTGCTATAGTAAATATATGTTGACTTGTGCACACAA GATTTGAAGCATCTTTTAAACATATATGATTAGATACAG AGAACACTGCATGTTGAAAACTTGAAATACAGGACTTTC TTAAAATATTGGGATTTCACATATATGGGTTGAATAGTT GAAATTTCCTCCTTCTACCTTTAACCAATTGTATATTAC 99 WO 2013/039990 PCT/US2012/054789 TTATTTAAAGTTGTGTTTTAAACATGGCGATATGATTAG ATACAGAGAACACTACTTATTGAAAGGTTTATGTGGTAT AGTATGAATTTTAACCTCAAAAAGGGTATCTCACTATCT CTTCATATAGAAGCACACATCTGATTCTGTTATATCTTT ATGGATCATTTTTTCCAGCTACATACTAGATGGCGTTCC TCGTATGAGAGAGAGACCAATAGGTGATTTGGTCACGGG TCTTAAGCAGCTTGGGGCAGATGTTGACTGTTCTCTCGG GACGAACTGCCCTCCCGTGCGTGTAGTTGGTGGAGGTGG TCTCCCTGGAGGAAAGGTATTGTGTTTTCATTAGTAGTT GTTTTCTATGCAAATAGCAACACACCTTATATATCATCC ATTTATAGCTATTTTTCTAATTGGGGCGTACGTTACTGT AATTTGATCGTCCAACCAGTTGTCATGACCCTCCTTAGC TAAAAT GGAT GAAAGCTGGTC CGACAATT GACCATAATA AATGGGTGTGGGCTATCTTGCTAAATTTAAGTATTTCAC TTAAAATGAGAGTTGGTTTACAGTGTGCATTCAACCTAA TTTTTTTTTTTAACGTCGCATACAACCTAAAATTGAATA ATGTTGTAGACACAAAAGCTCTTAGTGAGCTTTAATAGT AACATTAGAGGTGGTGATATCAATCAAACAATAAGGGAA AAGTAATATGTATAAAAATTAGAATTAAACAAGAAGTTT TAAAAAATAGATCAAATGGTTTGAAAGTCTTCTAAAGTG TAATTTAATGCATAAATCTTCCTAAATTATTTTATTTAA AAACTGTATTGTAATATAATTTTCATCATCATATTTGAC ATTCTATGAAAACAAATATACATTTTGAACAAACAGTGT TACGGATCGACCCAGGCAATTCAAAGCTGTCCATTCTAA CCTAAACCAGTTTTCACGGTTACCTCTATTTTCCTGCCT TTCAATTTGCCAGCTACAAGAAGCTTCATTCCACCATAA CGGGTTCACGCTAAAGATGCAAAGAGTCATGATTCGTTA TTTATTATCTTGACTTATTATGATAACAATAGTTTTGGT GTATTTTGATGTCTTCAGGTTAAGTTGTCGGGATCTATT AGTAGTCAATACCTTACTGCTCTGCTTATGGCTTCTCCC CTTGCCCTTGGGGACGTGGAAATTGAAATCATAGATAAA CTAATTTCCATACCATATGTCGAGATGACACTGAAATTA ATGGAACGGTTCGGCGTCTCGGTAGAACATAGTGATAGT TGGGACCAGTTCTTTATTCGAGGCGGCCAAAAGTACAAG TAAGTCTATTTCTTTCTTTTTAAAGTAAAACTGGAATTT AAAAAGGTTGCAGTTTCTACCCTATCTCTTGTAATGGGT TGATTCAGGTTATGTATAATCTCTAATGGGTCAAAGGGG GTAAAATACAAAAAGGTTATTTTGTCACCAAAACGATAT GATGCATATTACCTAGTTTTCTTATTGGAATAGTAAACA TTTTTAATCATTTCAATGTACAACTCTTTTATGTGTCCA CAGAAATTAAACATAGCCCCTAGGACTATGTTCATCATT TCCCTTTATAAACTAGTTGGAGAAAAGTATTTTGGCCAA CCCATTCCGAATTTACACATTTTGGCCTATCACCCAGCC CGTCTGTCCACTCATTTTCAGGGTTTTGTATGGAGACCC GTTTGTTAATTAGTTGGATTAATTATCTTCAGGTCACCT GGAAATGCTTATGTAGAAGGTGATGCGTCAAGTGCGAGT TACTTCTTGGCTGGTGCTGCCATAACCGGAGGCACCATC ACCGTTGAAGGCTGCGGAACAAGTAGTCTGCAGGTGCAC TTTGACCTCCTTTGTTTTTTATTCTTCTCGATTTCAATC AAACGGCTTTACGGTTTTACATTTTAAATGGATTTTGTG GAAACAACGAGTATTAAAAGTTCATCAAAAGATTTTATT ATTATTTTTATGCAACAATTATCAGCATCTGTAGTGAAA TATTCAGAAGTCCGTTTTTAGTTCAAAGTTTTTCTTTTT AACCTTAAAGTCAAAAGTGAGATGGCAAATCTTTTACGT 100 WO 2013/039990 PCT/US2012/054789 AAAATGATTCAATTGAGGCTGTACTTTGGTCGATTCTGA CTTAATTGGGAACATAGGTTACGTTAGCTATAAGCCTAT AACTATAAGTAAGCATGTGTTTATATGTCACAATGACTT GATTAAAAGTAACCTTATGATTTTCTTAGTATACGTTAG TAATCTAACAGTATCATAATAACGGACAAAAATGTGCTG GTGGATCAGCCCACCCAGCCCGTTAGAACATGACATAAA AATGACCCAACTTGACCTATCACCTAAGCTCATTATAAT ATGTTATCCAACCCACCCTATCTTGGCACCTGTGACCTG TATTCAAATGTATACTGTAAGCAACTTCCTGTTTTTCTT AAACATGTATTCTGTTTTTTCTTTCCAATGAAGGGTGAT GTGAAGTTTGCGGAGGTACTTGGACAAATGGGTGCGGAA GTAACATGGACTGAGAACTCAGTCACAGTTAAGGGCCCA CCAAGGGATTCTTCTGGAAGGAAACATTTACGTGCTGTT GATGTGAACATGAACAAGATGCCTGATGTTGCCATGACT CTTGCTGTGGTCGCTCTTTATGCTGATGGCCCTACAGCC ATTAGAGATGGTATCCTTCCTTTTAATGTGGAAAAAAGT TCAACATGTTTTCACTAAGTTTTCAAAGTAAATAGATAG ATATGACTTCAAAATAACTCTATTGCCATGTTAAATCTT ACACATATTGCAAGCACATTCTAGTGGTGGTTTGGAATG GCATTATGAAATTGAATATCTAAAATATTTAATTTAAAC ATGTTCGGTTTCTGATCATTTAGGGTCAGTTTTAACTGA ATCTCAGAGAAGTCGCGCAAGACATGTCACATATTTGTT TCTCCGAGTCTCAGACAACTGCTTTTTCAAAATGAAAGC ATTCTAGAACTATTTTGCTTACAGTTGATTTTCTAATTC TGGGTGTACATAAATCAAGATAATTACTTTTATAAAACA CATTCAAAAAGCCTCCTAGATGCCCCTATTATGAATTTT CTGTTTGCTATACGAGTATCTGCTTTGTTTTTGAAAATG GTTTTTTTGTTTTTTGCCAGTTGCTAGCTGGAGAGTTAA AGAAACCGAAAGGATGATTGCCATTTGCACAGAACTTAG AAAGGTAAAATGATACTTTGTTACTCTGTGATCTATGAT ACTGCTATTGCTTAGAGGTCACTAAAGTGGTAAGGTCAA ATAGGATGGGTTTGAATGGGAACACTTTTCGCCCAAAAC ATATTTAACTAATATAATTTCACTTGTTACTATCTAATT TCATAAATGAAATGATTTAGAATTAGAATGTTTTGGGTG TCTTGCAACCTATTCATTTTAAGCTATTTTAATTGTCTT TTGACCCATTAGAAATATACATAAGAAATATACTTAATC AGTCCTCTATTGTTAATGTTTATCTGGGGTGAAATTTCT TCAGTTGGGAGCAACAGTTGAAGAAGGTCCGGACTATTG TGTGATCACTCCGCCAGAGAAGTTAAACGTGACAGCAAT AGACACATATGATGATCACAGGATGGCCATGGCTTTCTC TCTTGCCGCTTGTGCAGATGTTCCTGTGACCATTAAGGA TCCTTCTTGCACACGTAAGACGTTTCCTGATTACTTTGA AGTTCTTCAAAGATTTGCCAAGCATTAATGTGATTATGG GTAGTGGTTTGCTTTTCTATATGTAATTTTTGTTTCATT TGTAACGAGTAAAATGTGAGTTTTGGGCATAACATATTC TTATGAACTTGTATTCTTTCGTAAGATTTTTTTAGTGTA ATAAAATATTTTGCTATTTCAGTTGATGATTTCTATTAC GGTAATTATGCATCTGACTTCCACTTATACTACGATGTG CATGGCTTTGCGTGAACAGATTGCCAAACAATTTAGTCA TGTGGCTGGTTTGATTGCCCACACTTGTTGAGTTGTTGG CTAGTCGAGTTTGGGTGATCAGAACCCATGTGGCTCGGT TTACACTTTGCGCCCTAACATGTGTGTTTTAAAGGTTAA TTAAACTTATTAAACGGCTTAGTAATTTAAGTCAATAAA ATCATTCAAGTTTCTTTTGTTCCTTTGGAATGATTTAAG 101 WO 2013/039990 PCT/US2012/054789 CTAATATGAAAAGGGTAC TTT TCTTAGACAAAAGTCAAA ATGTGAATATTTACTTTCAA-ATGAACTCTGGTTATTTAC ACGAGAAATGGGGCATTTTTATTTTGATTTTTTTAA-AAA AAGATC TTTC TTAT TT GTTAT TTAT TGTT TAGATAGTAT AACAC T TCAAAT TAAAC TAAATAAAAATAAATAC GAC GA GTAGTAAACAAGAAGAAC CAATAGGAACT TCGGCATT TT ATGAAGCCCAAGGTGCATGAACCTTTAAGAGCATATTCT TTTATCATATTTGTAGGAAATTGTATACATACATACATA CAT TATAATAT TATAT TGTATATAGAGAAGACAAGT TAT AT GTAC CATT TAAGGGAAGGCATGGGACAAGGT GCCAAG AT TCATAAACAAAGAGAACAT GGAT GCCT CGAC TT GTGA CTCAAATTGCTCACATGCTTTGCATCAATTTGATGACTT ATATATAATCTTAACGTATTATAATAACCTTAAAAGTGA AATT TAAC CCAT GC TTAT TTT TATACCTT TACAATCT TG ATTATAAGTTAAGATCGAAGCACTTTATGTTTTTTGAAA ATAGTTTTTCCATCCAA-AGATCATCTATGTGAGTAGGGA CGAAACCAGAACTTTCACTGTGAGAGGACAA-ATTTAGAA AT CGTAT GT TATAC TTAAGAT CT TAAGCT TTTT GAT GTC TTAAACTAGTCACTTGCAAATGCATCTACTAA-ATTATGT AAAAGTAGAACCTCACTTCAACTTTGTATTTTTAAA-AAA AAATTGGTAT TTAAAAAATAAGGCTAGTAAATGTTAATA TTAACTAAAAAAATCCTTTAAAAATAA-ATGTTTAGCTTC ATTTAACAA-ATTTGAGATTATGTTTATTCTAA-AAATATC AGAA-AGGTTAAATGCTTTGAAATTTTCTATTACTTTAAT ATTTGTCCATAA-ATTAA-AAA-ACCTATATATAA-AATATAA GGGTTAAA-AGGGTT TTCT TTAAAGTAAA-AGGGT CAACAT AACAAT CT CAATAAAGTT T TGAGAT TTAAAAGGAAAAAA TCTAAAAGGCAAGGTAACTTTTGCAAATATGTTGTCTTC CTCCCTTGGTCTCTACAACAGCAA-AGTTACAGCACCATT AAAACACAA-AATGCTTTATCTATTGATTTATCCATTGTT AC TACAATAATAAGCTCT TAATCGTATAAAGCATGGT TC CGTTATCACCTATTTAGGCTTTTCATTCTTTTTTAA-AAA TAAA-AT CCAAGTATAC T TTAAAAT TAAAAAAA-AAATAAT TAGAATTTAGCAAAATTGGACTGGGGGCAGTTGCCCCCA TTGCCCGCATACTAAATCCGTCCCTGTATGAGAGGTAAA ACATATTTTTCTTGTTATTGCATATATATACTACAA-AAA AAAATTCATTTGTCCACATTTGGTTATCGAA-ATTGTGAA AAAAT TTAT GAAT TTAAT CACAT TTAAA-AGT GT GTAAAA ATAAT TTACATAA-AAT CACAATAC TTATACAC TTATAAA T GT GTAAACAAA-ATAT TAACAC TTAAA-AGT GT GAACAAT TGTTAAATATTTTCATACTTAAA-AGTGTGAA-AGTCAATT TGTGACACATGATTTCTTCACACCCTACGTGTATAA-AGA AAATAAGTGTTACAAATTAACTTTCACACTTTAAGTGTG AATACCTCTATATTTTTACACACTTAAA-ACTATGAACTT TTCTTTTTCACATGTATAAGTGTGTAA-ATATTGTGATTT TTTAAATTTCTTCACACTTTGAA-ATGTAAATTATACACA TTTTTAAATGTGATTAA-ATTAACAAAA-ATTTTTACACCT TTTAAAAGTATAAAAAA-ACAAGTGTGAGGAA-ATGATATA TT TGTT GTAGTGATAAAACAATGTAAATATCAATGATAT TATAT CATAT CAC GAACAT GACAT GAAAAAGATAA-ATTA T CATAT TCT TAAT CGGAAT TATAAAAAAAAAA-AAA-ACAA AAAACAAAA-AC TAT TTCT CCC TTAC GCAATTT TAT TATA AAATTCTTGCAA-ATACATTAAACTATAA-AAATATTGATG _____ ____________AAGAGT CAAGTGAC CAGT CCC TTACAATT TAAT TAATAA 102 WO 2013/039990 PCT/US2012/054789 TAT TAAAAT CAC TAAAT CCC TAGTT TT TAAAT GAT GCCT TTTCATTTGTAGTCACGTTGTTTGTAA-AGGTAATACTTT ATTAA-ACCTTAAGTTAGCAA-AAA-ATAATTAAA-ACCATTC TT GTTAT CAT GT CATTTT CT TAAT TATT CAAAATATAAG CAGTGATATAGAATTGTTAGATTAATTTTGCTATTTTAA TAATAGGAAGAAATGTGTGGTATAAAATTGTTTTTTTCT TTTTGTCTTTTTAAAAGTGTTCTAAATTAATTTTTTCAT ATAT GTATATATATACAATAT TAT TTACAACAAATATAC TTATTTTATTACATAATATATATAATTATATATAACATA TACTTTTGTAAATGATTATAAATTATTGTAA-ATTTATTA CT CCTTAGAATAGAATTATTAAGTGAAA-AAATGCGACAT ATCATGTGAGAGTTGGATGCCACATTTAGTGTCAAGTTC ACAT GAT C C TCGAGTTTT GTC CAAC CTTC TT TACAGATA ATTCCACAGCTACGCCTTTTAGATACGCATACAAGAGTT TTGTCCAACCTTTTGTGAACAATTTTTCCCCCCCTTTTA AACGGTAA-ATACAT TTTTATAACATAATGTTAATGGAAC TTAAACTCGTAAATTTTTGGTATGTACCACATCAA-ATAT TATTAGATTATAAATGTCATTTAGTTTGCGATAATATAT TT TTGGTAAC GATCATTCAAAATAATTGATAGAAACAAA AATAA-AATAAAATAAA-ATATTGTGTTTGCTATTCGTGAA AAGAA-ATCCGTGGT TCAT TATAAGGTAA-ACAAT TATATG TGACTTGACATATGCTATACTTCTTAA-ATGACTTGGATG TATTTTGTTATTAGATGAGTTATACTTATACACTTATAT GCCTTGATAATGCCTTGATATTCATAACACGCAACAAGT TACTGCTTATAATTTGTGAACTACAAATTTGACTCTCCA ACTCTCCATAGTGATTTAAGAAATTGATTGATGATGAAT ATACTT TAAAATTT TACC TAT TCATATAGTTATAAGAAA AAAAGAGTAAGTGTTATTTATTTTGAACACAATTTTTTT TT TAATACATAAA-ATAGT CAAATCGAT TATTTT CAAGTG TGATATATGTGCATGTTATCTGATTGACGTATCAATGCT AGCTAATTAAACAT TAAATTAAATATATAAACT TATAAA GGACTTAGGATTGTACTT GCATAATATATATAGTTTTAA AAT GAT TCTT CT GATAGT TT TAT CAT GTC CAAT TGAT TT T GT TAGT TGT TAAATAATAACAATAAT GATAATAATAAA ATAAATAPKPATAAATAAATAATAATANNAATAATAATAA TAATAATGTT TAAGGTTGCAATAAC GTGTATAAAAAATT ATATTTATATATCAAAAGTTCTCTCTTGAATTTTATGAT AAATGTACATTTTATAACAAAATCTTTATCTTTATGAAA AATAAAAAAC TAAATT T TGATAT GAT TAAAAAAAAAAAA AATGTTTTAGTATGTTAGGCTCAACTCTCACGTGACATC AAAGT CAT CAATAAC TTAAGT TTAT TT TACT GTAC GAAG TCCCTGCAGATTGTTAA-AGGTGATCTTAAATTAAA-AGCG TAAAAGATCAAGTCTTCCATATAATAACCAATCACACCC TAATTTTTTTACCCCAA-AATCCTAATAA-AATTCATGAAG ATCTTGAATATTCTTTCCCTTTTACACCTCCCCCGTTTG ACTTTCTTTAAATGTATACTTGAGCTTGATTAATAGTCC AC CCTAATAAAATC TCAC CAT TTT CACAC CACAATTT TA TTTCAAATCTTCTTTCAAACTTTCACTCTCTGTTCTTCA C CAT TC TCTC TC CAAT CAACT TTTT TCT GCAA-AC CACAA T CAC TC CCCT GTT CAAGAAAC CT CAAGAT TCC GC CAT TA TCAAAAAGTTTTGTTCTTTCTTATCTTGTTTTTACATTC CTTACGCCAAGATTCAA-AACCCACAAACCTTTCATAAAA CC CAAGTCAC GTAT CAAGAAT TTAGCACATAA-AGTTGGC _________________TTCTTTTTTCATCTTCAAGATTACATCTTTTTATTCAAG 103 WO 2013/039990 PCT/US2012/054789 ATTTTTGAACAAGAATGAAGCTAATGGATGAAGATGAAA CCCCATCAACTCCTGGTAAATTCAAAATAGATAATAATA AATCCATATACATTCATCATAGATTCAGATTTCTACATT ACAAATCTTTAGCCAAACTTACATTCTGGTCCTTTGTTT TCTTGGGCTTAATCTTGGTTTTTTTCTTCAATTCCCAAT CATCATCATCACAAATTGTAGATCTTTCTAGAAGATCTT TAAAAACAAGTACATGGGGTGGACC CATATGGGAAAAAC GGGTCAAATCATCAGCCCGGATCCGAACCCGTAATGGGA TATCCGTATTAGTCACAGGTGCAGCCGGGTTTGTAGGGA CACATGTCAGTATGGCCTTAAAACGGCGTGGTGATGGTG TTTTAGGTCTTGATAATTTTAATGACTATTATGATCCGT CGCTAAAAAGAGCTAGACAGTCTTTGTTAGATAAAAGTG GGATTTATATAGTTGAAGGTGACTTAAACGATGTCGTTT TGTTAAAAAAGTTGTTTGAATTAGTCCCATTTAGTCATG TTATGCATTTGGCTGCACAAGCTGGTGTTAGATATGCTA TGCAAAACCCTAGTTCTTATATTCATAGTAATATTGCTG GTTTTGTTAATCTGTTAGAAATTTGTAAAAATGCTGACC CTCAACCTGCTATTGTTTGGGCTTCATCTAGTTCGGTTT ACGGGTTAAATACGAAAGTACCCTTTTCAGAAAAGGACC GGACGGATCAGCCCGCGAGTCTTTATGCTGCCACGAAAA AGGCAGGGGAAGAAATCGCGCATACTTATAATCATATAT ACGGGCTGTCATTGACAGGGTTGCGTTTTTTTACTGTTT ACGGGCCGTGGGGTAGGCCGGATATGGCGTATTTCTTTT TTACCCGAGACATTTTGAAAGGGAAACCGATACCTATAT TTGAAGGCCCAAATCATGGAACAGTGGCTAGAGATTTTA CGTATATTGATGATATCGTAAAGGGGTGTTTAGGGGCGT TAGATACTGCAGAAAAGAGTACTGGGAGCGGTGGGAAAA AGCGCGGGCCAGCCCAGTTACGGGTTTTTAATTTGGGCA ATACGTCGCCTGTGCCTGTTTCCGAGCTAGTTGGGATAT TGGAAAGGTT GTTGAAGGTTAAGGC GAAACGAATGGT GA TGAAAATGCCACGAAATGGGGATGTGCAGTTTACGCATG CGAATATTAGTTTTGCGAAGAGGGAGTTTGGGTATAAGC CGACAACGGATCTTCAAAGCGGGTTGAAGAAATTTGTGA GATGGTATGTTAGTTACTATGGAACAGGAAAGAAGACTG ATCACTGATATGATTAAAAAAGATGGAAATTTGTTACCT AAAAAAGACTAAATTTTTTTGTGTTATAATTCTTGTTGA TTTGGATTCTCATATTGATTGTTTTTCATGATATGATGA TGGTAATTGTTTGATACAAACTATATTGAGACTACAAAA GGAATATATTGTTTTAGTTCATTATTTTTGTGTGATGTG TACTAATAAGTAAGATTTCACATATGTTTTTGTAGGCTT ATTGTTTTGTGGATTTCACGAAAGTTGAGTATAATTCGT TAGATTTCTGATCTTTCTGAACTCGAATCTGGCAACATT AATCACACGATCAACCACGCCTGCTTGGATACAAGCACC ATACAGAAAGTAGTATCACGTTGAAAATGTCCATTGTTA CCACTGCTTTGGGGTTTTGCCTAATGTCCATGTTTTCAT TTTCGTTTTTTATCGATCTTGAACGAATCTAAAGCTAAC TTTAGAAAAGAACTGCAGACGCTTAACAAACCAACGTTA GTTGTTCAAATCGGATCAAAATGAACATTACTGGTTTCA ACCCGATTCTTTGTAAACAGACATTGCAAAGAGAGTTGA TCTGTCCAGGTAGCAATTGATATATTTATTATCACTTAA AATCAATTAAATGATGGTTTAATGTACATATTTTGCAAG TCAATAAATTATGTGACATTGTCACGAGTACACTACCAA ACAGTTGGATTTGATGTTGCTTGTGAGTTGTACATAATG CATTAAAGTATCTTCATTTGGAGATGTCGATTTCCGTTA 104 WO 2013/039990 PCT/US2012/054789 TGAAAAACGGTTGGTAAGCTTTTATGTGCAAGTATTTAA GAGATGTTAACACAATCTTTTGAGTTGTCACTTAAGAGT GCTAAAGGAGTTTGTATATGGTGGAACTTGTACTATCAA ATATTAGTTTGTACATATTTTCCCTCAAATTAGTAATTA AACGTCAATACTTGAATTTGAATACGGGATTTCCTCATC TCCTCTTTAGACAAAAGTTGTGCTTTTGATCTACGTTTG TTGCTTGAAAGTCAAAACCATTTTTTGTTGGAGTTGCTA GGGACTGTTATCATGGGTCGTCATACATAATCAAAAGAT TGTGATCTAATCGAGATATAAACTTTGTGGTGTTGAATG AAATGAGCCATTGTTTGTAGAATCTTAGCTTTGTTACCA TTGAGTAAGATCATCGGATAACAATTTTAGCAAATCTTG GCCATCTCATTAATATACGAAATACCATTTTTTATGTAA AATAATTAGTTACTACGTATATGTACTTATCATACAATG AACTGACAGTAATTAAGTTATAAATTTGATGTAGGTTTA GGTAAAACCTAAGAAAAGCTATATTGAATGTGCACTTTA TTATGTCTAGTTCATGAACATTAAAGGAGAGTAACAACC CTCGAGCATAAATGTGTGTAAAGAACATGGATGCCAAAT TTACTAATTTAATAATCAATACTGTAAAGGATTATTAGT ATTATTATTACTATGGGGATGGGAATATAAGGTTGTCGG GTATCTAAGCTTAGGTGTAGAACACTCACATATTGTTTT T 60 Conyza Genom 12729 CCTTTGGGTAGAGGCAAGATTGTCTACATCTCACCTCCC canadensis ic CCATACCCTGCTCACTGTGTTGTTTAGTTTATTTAAAGG TGGAAAGGAAAGGAGATGAGAGGAGAAATATATAAGATG CATTCTTAAGATTTTTTTAAGTGTGGAAAGGGAAGGAGT AGAAAGGATTAGAGGGGGAAGTTGATATGGATCTGCGGG AAGTTTATATTATTTAGTAATATAATATTAATTTTATTA TTATTATGATTAGGAAAGTATTGTCTTTACTTAGATATC TTATGATATCTTTTATATTATTTAGTTAGCTTGATCATC AAGCTATAGGATTAGTATAAAAAGAATATTAGGGTTGTA ATTCTAAAGTATGAAATATTAATCAGAAGTTTATTGTTC TTGTTTAATCAATTTAGGAGTTTACTGGTTCTCGAATAC CAGCCTATCTTTGTTATTGTTCTTATCATTTGATACAAG CCATTGGTTCGTATCAATTGGTATCAGAGCATCGATCTT GCAACCTGTGCTTTTCTTCAACTATGGAATCAAGGACGA TCATTGATGTTGATGCTGATGTACAGCAATACCGTGAAT CTACTGAGGCTTGGGTGGACATAATGCATGCTCGGATCA ATCGTTTTCAAGCAGCCACCGCGCGATCTCAGTTGGCCA CTCAACAATTTCACTTGAGGTTTACAACTAGGCTGGATA AACTTGAACCAGTTGTAGTTGGGACACAGCAGAAGTTGG ATGCATTGGCGGCAGTGGCAAACCAGCCTCTACCCCAGC AACCGATGATTCAGGAAGTTGTCATACCAACAGTCCCTA CAACTTCACCAAAAACAAATCAGTTTGGGTTGAAGCAAT CGAAGGTTTCACAAGCAGGGTATCCTTATCCCAGACACC TTCAGATCTTGCAAGGAATAATCATCCTGATGTGAACCA AGAACGAGGAGCTGGACTAACATTCAAGGACATAAGCAA TGCTTATGAAGATCTGGCAGGCGATGAAAAGCGATCCAT ATATGACATGAATGGGGAGAATGGGCTTAAAGGTACATG TTTTGGTTTAAGGAATTGTGCAAAAGCTGATGAACTTTC TGGTTTGATACATATGATTGAGTTTGTTAAACAACTTCG ATATGATCAGCAAGCTATGGAGTTTCAAGTCAGAATTTG GGATCCTGGAATTACTCGAAGGAACAATTTAAAGCAACA CCTTGAGGACAAGGTGTTTTTGGGGTGGGAGTAATGATA TGGATCTGCTGGAAGTTTATATTATTTAGTATTATAATA 105 WO 2013/039990 PCT/US2012/054789 TTAATTTTATTATTAATATGATTAGGAAAGTATTGTCTT TACTTAGATATCTTATGATGTCTTTTATATTATTTAGTT AGCTTGATCATCTAGCTATAGGATTAGTATAAAAAGAAT ATTAGGGTTGTAATTCTAAAGTATGAAATATTAATCAGA AGTTTATTGTTCTTGTTTAATCAATTTAGGAGTTTACTG GTTCTCGAATACCAGCCTATCTTTGTTATTGTTTGATAC AAGCCATTGGTTCGTATCAGAAGTTTAGTTGTTTTTTGT CTCAAAAGTTTTCCCCTCATTTTTGAGGTGATTAGGAAG GAAAACTTCTCTTCCCTCTCATCTCCTTTCCTCCCTTAA GTTAACTAGACATTAATGAATATTGGGTCATTTTGTTGT TGTGGCTATAAGGAATGACTTGACTTAAAAACTTATAGA AATGCTGTGTTATCCAGTAAGTAATCGTTTTTTTACTAT TTGTCTTTTAAGACCATTCATTAAGCACATAAAACAAAC AACAATCCTGCTTAATCGATGTAGACTACATACATGTAG ACGGACATTTTATCCATAAAACAGCTAATTAGTCATACA TACCAGTTATATGTTTTACATCGTGCAGTGTAAAACTTC TGCCTTTACTGCTAAGATTTTTTGTTTACATATATATTA GATATATTAAGGTTTGTATTTTGATGCTAACATTTAACA TTACTTTTTTTTTTTATCGGGGAGTGGGTTAAAGTGGTT CTTCTACCTGGTTTTAGTTTTTTAGATGTATATCCAATA TTTATTGTGGGTAATTTAAAGTTTTGAAATTTTTGTTTT TTTTTGTGAACAGTATAAAGTTTCTGACTTTTTTGATTT TTTGTGAGGTAAAGTCGTGAATGTGTAATTTGGTATTTG ATTGATATTCTTGATATTGGTACATAGTGAGGTGCAAGG TGCTGATGGTTTCTTAGACGGGTCATGTTTGTTTTGTGT AAAATACATCTGTTTTTTTCTTTGATAACAAGTTATAGA AGTTGCACCCAAAAATGTTCTTGTTAAAGCGATAAAAAT TTGGATAGAAGGTGACGGTTAATGATTCGATATATTGAT TTGAGTTTCCTTTTATCTATTGCATTTTCACAAGTTCAA CATTCCACCCTCGATTTTTTGATGAATCTATGACTGAAG AAAAGGGCGATTGTTGCCTTTGGCAATCAGTTTTGGATT TTATTTTGTCATGGAAAGGGGGTGTTAGTTCCTGAACCT TAGTAGAAGATGATAAGCTATAGTTTCAATATTGCTTTT CTTTCTTGCATCTGAACTGGTTTTGCATTTTTCAAAGGA CTATAAAAGATGCTATTTATCACCTATGACCTATGTTAT AAATAGTAAGGTATTAAACTATTAATATTGGTATAGTCT TGAGAAATCCATGAATTTCGATTGAGTTCATAGGACACA TCTAACTTATGTTTCTTTACATTACGATTTACACATCTT GTCTTTGACGTCTGATTTTAAAATAGCGTTTCTATTGAC ATTATGCATTTCTTTGAGTTCTCTATATAAATTTTTGTA AGCTTTCCATATGTATATACTATGAATCTGAGTGAACTT ATGCTATCAGGGGACTACTGTTGTAGACAACTTGTTAAA CAGTGATGATGTTCATTACATGCTTGGAGCTTTAAGAGC TCTAGGGTTAAATGTTGAAGAAAATAGTGCAATTAAAAG AGCAATCGTAGAAGGTTGTGGTGGTGTATTTCCCGTGGG TAAAGAAGCCAAGGATGAAATCCAGCTTTTTCTTGGAAA TGCAGGAACAGCTATGCGTCCATTGACTGCTGCCGTTAC TGCTGCCGGTGGAAACTCAAGGTATTTTAACTTAGTGTT ATATTCTCCTGCATTTTATGTCTGCTTCATCCTCCTACA CATACATTTCATGACATGTGTACCCATTTCTCTCACCTC ATCATTTCATTTTTCTATGTGTCACAATTATATGAGTAG GAGGATTCATACTTTCATAGGCATAAATTGTAGGAATCA AATATCGTTTCTTTTTAACCTAACATCTCTTGATTAGCT ATTATAATCCGTAGAACGTATATTAAAGTTTTTTGTGCC 106 WO 2013/039990 PCT/US2012/054789 GATATGTAATTTTAAGGTGAATACACAAATAAAAATTTT ACCTTTCTGTTTGTTGCATGTTCTGTACATATAAATTTT TAGTTTTTGTTATATATCTAAGAATCTAAGATCTCTAAA TATTCTTCTATTAGTTGACACAAATTAAGGGATCACATG AACTGAAAACTCAATAGCATCCACTTGTTGATAATGCTG CAATTTAATGCCCAAAGAAGAAATTATTGCAATTCTTAT TATCATTTTATTTATGGGAGACAGTGAGTATGAATTTGG GAATCGATAATAGAGTTGACCAACTTGGTGGTGCTGGGT AGCTAAGGTAGTGGGTAAGTTACATTGATATGTAATACC CTAACAGTTATGAGTTTTTTCTTCAGCTACATACTAGAT GGTGTTCCTCGAATGAGGGAGAGGCCAATTGGTGATCTG GTCACCGGTCTAAAACAGCTTGGTGCAAATGTTGATTGT TCTCTCGGTACAAACTGCCCACCGGTTCGTGTAGTTGGA AGTGGAGGCCTTCCTGGTGGAAAGGTAATCAACAATAAG ATTGCTGCATTTTAAAGTCGTAAGAATTAATTATTTGGT TCCATATATGATTGGAAAATTTGGTTATTTAAGAAACTA TTAATTAGTAATGAAATTATAGTTTTTGAATCTTTTTGT AATCTTCTTTCCCTGGCCTTCTTATTGCAGGTGAAATTG TCAGGATCTATAAGTAGCCAATACTTGACTTCTTTGCTT ATGGCGGCTCCTCTTGCACTGGGAGACGTAGAGATAGAA ATTGTAGATAAATTGATCTCTGTACCATATGTGGAGATG ACACTTAAGTTGATGGAGCGGTTTGGGGTTTCAGTAGAA CACAGTGATACTTGGGACAGATTCCATGTCCGAGGCGGT CAAAAGTACAAGTAAGTTGATCATTTCATAAAAGTCAAT TTTTACGTGAAGATCGGTCAACATCTATTTTAATCCGAT AAAATCTCTTTAGGTCACCTGGAAATGCTTATGTGGAAG GTGATGCTTCAAGTGCGAGTTACTTCTTAGCTGGTGCTG CCATCACTGGCGGAACTGTCACCGTGGAAGGTTGCGGGA CAAGCAGTTTACAGGTATTATCCATGTGCCCACCTCAAA GATATTCAAAAACTAAATTGTTTCTCAAGTATATATTCT TCTAGTTAATTGCAAATTTTTTTGCCCCATACGTCTACC CATTCTATAAATTTCGTCCAAAGTTGGTGACTCGGTTCA ATCGTGTAATAAGTCTCTTTTTTGTTTTTTAGAATTGAC AATTTATGTCAGTTCTTGGTTATATCAACGATGTGGGAG TGTATTGTGCACACATTCTAAAAGAAGGACATTTAGTCT TTTTGCTTTCTTTTTGCCTCAAGATCATCTTCATCTTTT CAAGATACTCTGCACTCATTTGCATTATCAAAGTTTTGG ATGCATTCTGTAACTGTGGTACAAGGAGGGAGACATAAT ATGTCATTAGTTCTTATTCTTAAGCTCAATGCACACTAT CACCTCTTACTTCTTTTTTCTTTCTTTTTTTTTATTAGT TTATTTAAGCTCAATGCACACTAACACTTCTTCTTTATA ACTTCAAGTCATTCATTTTAATTTTTGAAGCTGATGGTT TTTGACATTAAAGATAGAACTATGTATATACATATGTCA TTTCATCTTACCTATTTGCATGTCTTGTTGATCTTTAAT CAGGGTGATGTAAAATTTGCTGAGGTCCTTGGACAAATG GGTGCTGAAGTAACCTGGACAGAGAACTCTGTCACGGTG AAGGGTCCGCCAAGGAATTCTTCCGGAAGGGGACACTTG CGTCCAGTAGATGTGAACATGAACAAAATGCCGGATGTT GCGATGACTCTTGCTGTGGTTGCCCTTTATGCTGATGGC CCCACTGCCATTAGAGACGGTATGTGTTAGAATTCACCA CAGCTTTGTAATGTTAAATATATGTTAGTTTAGATTAAC AAAAT GAC TATAT GAT CACAAAAGGAAACAT T TAT C T CA AATTTGGAACTAATATAGTATCATACCTATATAGCAATT GTAGTTTCAAAGAAATCCTTAAGGTCGTGTTGTTTATTA 107 WO 2013/039990 PCT/US2012/054789 TACATGACTGGGTATATATTGTTTTTTGTGCTCAAGCTT TTAAAAATCACATTTGACTATCCTTTATTGAAAGGTTAA TTTTGTTCATGTCTCATTTTAGGCAATTTACTTTTTATC AAGGAAAAAATAGCAAT CAAT GTC TAT GT C GTAGTT TAG GCAATTAAAACCCATCAATCAAAGTGCTGTTGGTTCAAG GCATATTAGAGATAAATGAGATAATAGTACGTGGATGTC TTTTCAAAAGAAGTACAAACTTTTTCTTGGGCTCTTTAG TTTTTACTGAAAATACCAAACTCCTTTAACTGAATTGTC TAAAATAGAAGAAACTGGAAATTAGTTGCTATTTTGTGA AAACGAAAAGTAAATCGCCAAAAATTGGAGGTTAAGTAT GCTTATATTTTATGTAATTCATCTTTTTGAAAAATGTAA GAACTTAAATGGAAGTGAATTGATTTGAAAAATATATAT TAAAGCACCACTTATGAAGAAATCTAGAAATTGAGTTTT AGGATCTGTAAAGACATCCTGTATATTGTATGAGAATAG ATATATCGTACACCACAATCCATCATTTTTACTTTTCAC ACGACAAAGTGAATATGAAAAATGTGAGTTAAAACACTT AAAAGACAGTTTTGGGTGTGCAAAGTAAAATGTAGCACA AATTGGCCCCTTTCTCATATTGGGTTTACATATTCTTCT TTACGTATATCCCTATATTGTTCATTTTGTGGGCCCCAT CTCACGTCGGTAAATCATTAGATGGACTAAATCATATTC TTCATTCCTTATATTGGGCAGTGGCTAGCTGGAGAGTAA AAGAAACGGAAAGGATGATTGCCAT CTGCACAGAACTAA GAAAGGTACAAGTCATTAACCCATCTTACTCTAAAAAAT AGAATGGCCATGAGTACTTTTAAAGTACTCAATGAATCT GCCCATTATTTGTTTAGTGCTAATAGGCCCTTTTGCCCT TGGAACTTTTCAGTTGGGAGCAACAGTCGAAGAAGGTCC AGATTATTGTGTGATCACTCCACCAGAGAAATTGAATGT GACAGCAATCGACACATACGATGATCACAGAATGGCCAT GGCTTTCTCGCTTGCCGCCTGTGCAGAGGTTCCTGTCAC CATTAAGGACCCGGGTTGCACCCGTAAGACCTTCCCCGA CTACTTTGAAGTTCTTGAAAGATACACTAAGCATTAAAT CACATATAAGATGTTCAGAAAGAAAGGGGTTAGAGGTTT TAAAATGACACCTTTACCCTTCAGTCCTTCACCATTATC TTTCTTCAGAAATGTTTCACTTACAGAGTTACATCATAT GTATATGGGCGACCTGAGCGTATTTTATCTTTTCTTTTC GGTGAGTTTGTAGTTTTTGTTGAGGTGGAATAAGTATTA TCTTGAATATTTATGCTAAATTTGGTTAGCAATGTATTA TTTTTGATGCATAATGTATTTGTTATATTATAATGAAAA GTGTTTTTGAATATGGCCAAGATTTGTGAAGGTGAGATG AGTTTTGAACCTTATACTCAGATTTAGCACATGGTGACA C TAAATAAT T GATC CTT TAT TAGT GCT GAAAATAAT TAT ATGTTAAGAAAGATTGGTTACTAACAAAAGTGGTTATGA GTGAAAGTGGGGTTTAAGTTTGAAGTCATAATTCTCTTG AGATGTTGATTTGAAGTTGAGATGTACGATAGGGGTGTA AAGGCACCTTTGGGATATAAACAAAATCATGGATTATCT TATTCCTTATACTTCTATTGTATGTTAATTTTTAATTCA ATTTTACTGAATTACTTAAATGATATTTTGAATACTATA AAAGGTTGGTATTACTCCATATGTTATATGAGTCAGAAA TACATTTCGTAATTTGCTCTACATTATCTTAAGTAATAT TTCTCTTCTAAATCCAAATTACTAGTTAATAATATATAC TAGTAAAAAT GTAGCTATAAGCCTATAAC TAAAACCT GA AAAAT GAAAAAGAAAATAAAC GC TATATAAAT TAT GGAT T CAT GCAT GTAT C TAT TATATAAATAAAAGAAAAT T GT G ATGACATCATATTTATTAGAAAAAAATCTACTTGGCATC 108 WO 2013/039990 PCT/US2012/054789 ATTAGACATTCACATATTAATTATTTATTTTTTTTATTT AATTGATTTATGACATCAATATAAATAAATAGAATTTGA TAATTCTATATTAGGAAATATCATTACTTTTAAAGATTT TGTGGCACTATTAC TCTATTAGACATTTATATAATAATA CTTTCTTTTTTTATTTAATTGATTTATTTATAAATAACT AAACTTTAATTTTTAATTCCCATATTAGAAA-ATATCTTT AGTTTTAA-AGATTTTTGTGTGGTAACGGTTATAACTTAA AT GTTCATAGAGTATTATAA-ATGAATAT GAAAGGTCT TA CACATTTTAATTCTTATATAGATTGTATATGTGTTTATA AAAAA-AATCACATTTTGTACAATATCTTGAAGTTTTTCT TGAATTTTATTAAATTTTGTGTTATATATCAATGGGTTG AATGTTAA-ATAA-AT TTTCATTATATAATT TTAGGTAAAT TTTACATTATATAATTGTCCTCAATAATTATTTCTTTAG TTTGCCCGCGTAATACGCGGGTTACTTAGCTAGTCAAGT GATAAAGTTC CATT TAGGTAAAA-AC TAAAAAACATGATA GAAGAGTT TAC GT TAAT TGTAT TAT TTAT CTAAAA-ATTC TATTTTTAGTTTCGTAAGTTTAGACTGATCGATCATCTT GCAACT CGAT GT TATACAT GGCATT TTAT CT TAAAA-ACT TTTACCCTTGTATTTTTTTTTTTTTTTTTATTGTTTTTC T TTAAACAT TCATAT CTATAAT CAT GAAAAGAAATAAAA TAAGAATTAGCGATAAGC CAGATAAATACAAA-AGGAGAA AT TTAAGTACAA-AT GAAATTT TATT TCAT CT TAT GGTAC AATGTAATAAAA-AGTTATAGGAAA-ATTTAACTT CAGT CC TAAGATTGTTGTTAGCGTGAATAA-ATAATTATACTTTTT ATTTTAAA-ATTAGTTTGAGCGCGTTAAGTCGTTATTGGC AACCCATAGAGTTGTTATTAGCAATACTAAATTTTTTAA TT GTGGATAGCCAAAATTAA-ATGGATGGGAATT TCCAAT GACACACCGGTCTAGTGTTAAGACACATGAGATTTTCTT ATAAGT CGGAAGTT CGAGTCT TGT CAAGTACAAGCTT TA TTCATATTAATCCCCAAGTAGTCTATGGTGATTTCTTTT GGCATTGTTGCTCGGCACGGGGTAGTAGGATCCGGTTTA GACAAC CGAC CAAC CGCT TTT TGGGT TAGGACC TCAT CA TTTGATGGTGAAGGATATGTTTCTATTCGAA-AGTCATTT GT TAAAAAATAATAAAAAT GAATAAAT GAAC GGAA-ATTA TATGCACCATAACCTTAGAATATACTACCAATATTCCAG GTTTATACTTGTGACTTGCCAACATTTATTGTTGTTGAT TGTAATAATGCTCATGTTTCCTTCATTCTTCTTGTATAG TTCCTTGAAAAAATTTCTTGTTGTTGATTGTAACTACAA TGATTAATGTAGAAGAAACAATGGTTAA-AAAA-AAA-ATGA TATTTGTACCATTTCTTTTGATTGATGTATCATAA-ATGT GCATTGTTAACTTGTACAGTTAGTTATACAATT TGTACA TTATTATACATTAATAAAAA-ATAGTGATACTAATATCAC AAATTAAGCGTTAAAACAGTGTGGGGTGGGGTC TAAAAG ACTAACTCAGTAATTTATGATACTTGGAAATTACTCTTT TCCCAATTAAGCTTGCAATAAGTTGAAGTTTGGTGGTGT AGTAGCCAGCCTTTTTACTCTTTTCACATATATACAAAC TCACAT GATGTAGGTGCTACC CTAACCAACAAAGTTGGG GAATTTTGACAATAAAGGCATTGAGTGTTTACCTAATTT ACAGTCAAA-ATCTTGACACATATGACATATATACATTAT GGCAAGAAA-AAACAAATATAT CCTAAGTT TAGACCAACA CCATGTTGTTTTAAAATGATATTAAATATGTAAGTTATA TACATTTCTACTTATTGGTTTTAGTGGTTTATTTCTATA TTTGCTATAAAAGTATAAATTATGGTTTTCCAATATGTT _______________TTGTTTAGAGCTTTAGCCGTTGAATTCATGGAAGAATGA 109 WO 2013/039990 PCT/US2012/054789 CATTTTGGGGTAAGTTATTGACATGAACGGGCTAACACC TTAGAAAAAATTATTGAAGTATTTATAGATGTGTGTAAT AACTCGAAGACATGTATCAATGTCAATAAATAAGGTAAC GAGAGGAAAAATAAAC T TAT GCAT CAAC GAATAAAT GAA TTAGGTATTAAGATATGATAAAATTGACATGATGTTTAC TCTCTTTTCTTTTTTTCCAAAAAAAAAAAATTATCGTTC ATCTTGAATTAATTAGTTAGTTTTTTTTTTTTTTTTTTT GAAAAGTAATTAATTAGTTACTATCACAAAGAGTGTTGA AAAAGCCCTCATTCAAATGATTATTCCAATTCAGGAAAA T CT TAACACAAAGTACACAAC TAAAAAGAGGACAT TAAT CAAAACATCATACT CAAAACATTTGATAGTGAACAATAG ATCAATTGGCTGGAGTTTTTTTTTTTTTTTTTTTTTTTC CTGATCATAAGTTTGACTCTTCAAAATGACATACTTTTA GGTTTTCTTTTGACTAACTTATAACAGCTTATGATTTAC ATCTTGTAATTTAAAGTATGTGTAGGGATTCACCATTGT ATGATGAGATATCCCCTGATATCAAATAACAACTGACTC T T GAAGAAAAACATAC TAAT C GAAAC CAAAAAAAAAAAA AGAACGCCAAAGTTGTAGATGGAGTTGTTCATAAGCTTA AATTCCTCTTGATCCAGTGGGTATCTTTGGTGCACCACG TGAATGCTGATTTCCTCTTGAAGTTATTAAGCTTGTAAT GACAACAACTATGGTTTAAAATGATTCTAGAAGTTAAAT ACTACGAGGTAGACATTTTTTCATCATTTGTTAGATAGG CGCATTTTGAAGATCGTTCAAGTCGTCTTCAAAAACGTC CTTTTTACCTAATGATCAATCAAGGCACGCACCTAGCTA TGAGATGAATACGTTGTTGATATTCCGCTTTTCGTTATC ACCATTCATCTCGACACGACGTATATATCTATATATATC CCAACTCTAGATTATATTCATAAGTTCGTATATTGATGA ACTATATATGTGTTATGCACATGCAATGCACCCATAACA TGGAAGAAGAATTATTGCTTTATTCATTCATGTGGAAAA TTAGGTATAATGGAATACAAT GAAGGAACATGACAAAGG TGTTACCCAATCACTAAAATTGTGTTTGGCACTAATGGA GCATTGCAATTGTACTTTCTAAATAATCCATATCTTTAA TGGATGGAAAGTTTCATACTTACTTATTACAATCAGTAG ATAACCATAAAAATGACATTAATATTGACCTTTAATTAA TAGAATTTTAGAGTTTTTAACAAATCTTTTGTCATGGAC TTCGTATGTAAATTGGGGAAATGCAATTTGTCTTCTATG CAAAATACGAAACCAATTAGATCCAAAAGGTAT GATGAT AGTAACATCAATCAATACTCATTTATAAAAGAAGGTTTC CTTTCATTTTCAATTTTTGTGTGCTCTTAATATAAACCT CACACTAAAAATGACTTATCCCATACTCACATGACATGT CTCTTAACTTCCCTTTCAATTAGCTTTTTTTTTCTTCCA CTCCTTTATTGCACATCTAAAATTAATTTTTAAAAATAT GACTAATGACTTTTAATCAATTATGGGACTAGTTAACTT ATTAAAAAAGTATCCCCTTATTGAAAGTTACATAGAGAA ATGTTTAAATTACTCTCCAAATTTAATTATATAATATTT TCATCTAGCACCCCTTAAAATATATTCACATAAACTATC CCCTTAACATTAATGATTAAGTTACACTATCAATCGTTA ATCTTTTAGAATATCTTCATTAACCCTAGCTATAAATAA ATTACTTTTATATCAATTATTTACACCACTTAGCGTCAC TTCCACCACCAACAGTTGTCCCATCATCACACCGTCACC GCCACAACCACTGCTGCATTGCGTGGATATAATGCTACT ATAAATAATAAATAGTAAGCTTGTAAGGAAAAAGAGTGC CTCAAATACTTTTCTTATAACCCATTTGCAAAAATAATG GATATCTTAGAATGGCTAAGGAATAACTTATAGCATATT 110 WO 2013/039990 PCT/US2012/054789 TTTTAAAAAAAAATAACACTTTATATTTGGAAGTGTTGA AAAATATGTAATATTTTTATTTAACACGCCTTAAAATAT TTTTACATACACTATCCGTTAACATTAGTGATTAAATTA CACTATCAATCCTTTATTTTTTAAAATATCTCCATTAAC TCTTTACATCAATTATCTACACCACTCGACGTCGCCTTC ACTACCAACTATCGCCACCACCACACTGTCATCGTCACG ATTACCGCCGCATTACGCAGGTACCATGCTAGTTGAATT TAACTATAATAACTATGAAGTGAAGTTGAATTAATCAAA GTTATGAAAGACGAAAAAACTTCACTCACTAAAAACAAT AGAAACCTTATTCTTTTTACAAGTGAATTTTACCTCAAA CGTGTATGATGTATGCAAATCGCACAACGAATGGGTCCC GCACTAAGCGGATCTTAAATAGTTTTTCTCACCATAACA CCTCCTTAATTAGAAAATATCGTCGAGGAGAACCTACCA AAACTCGAACTCAAGATCTTGGAATAAATTCTCCGGAGG CCCCGCATAGCAGGTTTAGTGAAACACCACTGGCCATAA ACGAAATGTAAATAATTTATTTCAAATCGTATAAATTAG AAAAAGCAACACGTTTGGCAAAGTTTCATTTCCCTGGTA TTATTTATAAGTTTTCATTAATATTCCAACAACTAAAAA TGGTAATGATGAGGAGTTATCAACGAATGTCAAAACTAA ATTCATTTGTATACTCACAATCAAATATTAATCAAAACA AATCTTTAATATTATATATCATCACTAGAAACTAGAAAG TAAACATATAAAATTGAGTGGTAGATTATGAAATATTAT ATAATAACGACCAGTTAAAAAGGTTATAACTAAAGGGTT GTGATCAAATGAATC 61 Conyza Genom 2833 AATCTAATAAAAAGAAATTTGTAAGGAATTTGTAAGCGG canadensis ic AAAGTCCCCTTTGTCCATTTTGTAAAGACAATGAGGAAA CAATTGACTATCTTCTTACTGCTTGTCCCATTGCAAATG TGGTATTATGTTTCCTCATGGTGCCATATACCTCCACTA TAGGCATACTAGGCCAAAGAGTTTTTCCTTACAAACCAG CTTTCTCCCGAGGTCTCATTAACTAAACTTAGAATCATT AATCTTATCATCCTCTCATCTGGTTGGCATATTTGAAAA ACTCGGAAAGATAAAGTCTTTTATTGTAAAGATCTAAAC CCAAATTCGAAGACATAAACATTCAACACTCATATGGTT AACTGTGAGATCAAAGTTTAAGGAGCTCGACTCGAACTC CTGGAGCTCCTTTAATTGTAATACGGTAACTTATTTTGA CTTTGGTTTTGCTTGTACTTTCCTAGGACAAGGAGCCTA AATTTTGATTGGAGAAAGAGATACAGTGAGAGTAGGTAT GTATTTTCTAAAAGACACGTAAACCTCAAAAAGAGCGTG TGGTAATGATAGGGATTCTTATAACTTATTTTGACATTT TGTAAAAAAAAATATTTAAAAAGAAAGATTAATTGTCGA ACCTCATGACAGACCTAAAAAACCAAAACTATATCCAAC TAATCTAAAACCTTATTTGTTCCATAATCGGTAAACGTT CTATCAATAGTGTTTATATGAAGTATACAAAGTTAAGCA TTGCCATTGCCACTAATGATATAACAATCTTAACCATTA ATTTTCATTCAATGGTCAAGATATTTTCAACATGACGCA AGTTGAGAAATCAACTTGAGGGAATTTAAATTCCGTAAA CTCAGCTTTATGTAGAACAAGGTGCTGATAACGTGTGAT AAGATTATTGTGAAGAGAAATATAGAGAGGAAGAAATTG TATCTTTCATTGAGAATGGGGAGGGATATATATACACAA GTCTTGGAGTAGGCTCCAAGATAAATGAGATAAACTAGA AAATGTAATCTCTCTAAAACATACATGATACACATAATC ATTTTCATTTACAATAATTCCTTTAATAATAGTCATTGA AATTAATAGTGTCATCTCCATTGAATGTTTGACACCTGT AAAAAAAAACGTTATATATTAATCATATACAAAAATTAA 111 WO 2013/039990 PCT/US2012/054789 ACAAAATGTGACTTTTGGAAGGAGTGGCTAGAACACATG CTAATGTTTGAGAGATTGAGTGTTCGAATTTAGGCTGCG TTTTTTTATATGACCTATAAGTTTTATACTTTTATAAGA TAAACACATATACACTTTGTAATATTTTTTTCTTTTTAG TAACATTTTTGTTCGTTTATTAAATATTTGTCTAACTAC TGTATTTCTTTTTTACATTTTGTTTTACTTTATAGTAGG TAATTTTATTTTTAATACTTTGTTTTCTTGGGATTTTTA GGAATACACATATGGTATAGTTGTGACAAATGTATTTGT ATTGATGTAAAGGTTACATTTGATCAAATGTATAGTTGT GACAATATTTAAACATGAGAAAACTACGGCGGTGAATTT GTCTACTTTAAAAATATGGGTTAGTGGGGCGCGGTCAAT CTTTCTAGTTTAAAAATATGGGTTGGTAAGATGTGTAGC GGGGGCGGGGGTTGGTGAAGGAAATGACACTCTTCTAAA AGCCGCCTACCAAACTCCCCCACCATCACCTCATCACCC ACCTATTCATTGATTCAAATCCCACATTTACTACGTGTT TTCTCAACCAAAATCCCCCCCGCCCCCCCACAAAACACA CAATGGCAGTTCACATCAACAACTCCAACATACCCATTT TCAACACTTCCAATCTCACAACCCAAAACCCATCTTCAA AGTCATCATCTTTTTTATCTTTTGGATCCAACTTCAAAA ACCCATTAAAAAACAATAATAACAATAATTATACCTCTG TTTCTTGTAATGTGAAAAACAACAAAAACCCATTTAAAG TATCAGCTTTCTCTGCCACTTCCACCAAAGAGAAGCCAT CTAAAGCTCCAGAAGAAATTGTGTTGAAACCCATTCAAG AAATTTCGGGTACGGTCCATTTACCCGGATCCAAGTCTT TGTCTAATCGGATCCTCCTTCTTGCTGCCCTGTCTGAGG TATCTTTTATAAATTATGTTTTGAATATTTGAATTTAAT TAGTGTTTTGATTGATTGACTAGAATTTGATTATTATTA AGATATAGGAAAAGATATGTACATTAGTTTTTGACTGAA TGTGAAAAATGTCTTAATGTAGTAACTCACAAAGTTTTG TTTGTGATCTATAAGTTTACTTTATAAGGTTACTCTATG GGAAAAGGTTACGTAGATTTTGGTTTTCTTTGACCTCTG TAGTTGGTATGGCCATGAGAAGAAGTAGGCCTAAAAAGA GCTTTGCTTGTGAGAGGACATGACCATACTTAGAGGACT AGGATTAGTTTAGAGGAATATGGTAGATCAGTAATCCTT TTAGGTATTTTAGGGGTAGTCTATATACTTATATGTAGG AAGGTCAGGCATGATACCTTTCTTATATGCTCGTATACT CGTAATTGTTGCTCTCAGTCCATTTGCTTGGTTTTATGC AAACGGTTATGTTTATTATGTTTTTATGCTGATGTCTAA TATGTTCAAATGTCCTATCTACTATGTATTGTCCATTTT GCGCTAAAGTGTCCTACGTGGTATGTTTGCTACTCCCCT TTACTCTTAACGTAGGCAGCTCATACCCGACCGACAAGT ATGGTTTGCTTAACTCTTTACACTCTCCTACTTTTGCAT CATATGGCCGGAGGTCCTTATGGAA 62 Conyza Genom 15010 AATATCAACAAAATCTTTCACCATGTCAAACAACGAAAA canadensis ic CCAAAGTAACGACCTTTGGAATCACTTTCAAGAAAACCC GATGCTGAGTATGCCCCTGATGCCGCCTATACCGGTTAT ATCATCAGCTAACCAAGGCCAAACAAGCCATGTTTCAGG CTCATCCAACCCGACCCCAATGGGGAGACCAGTTCCGAC GGGTTTGTCGCAATACGACCTAGAAGCACATATGAGTTA TCGCCAACACTTGCAACAGAACTATGCAAGCTCGTTTTA TGCACCACCGGCGGCACCGGGGCCACAACCGGGTCCTAG CCACGACCCGGAAGAGGACGAGGATGACCAGACCGCCGA CGGCGAGTAGTTTTTTTAAAATACTCGTAATGTTTTATT TTTCTTTGCAATGTTTTATTTTTAAGTGTGTTATGTGTT 112 WO 2013/039990 PCT/US2012/054789 TTATTTTTAGTGGTAATGTTTAATTGTAATGTTTTTTTA ATTTAGTTGTAATGGTTAATTTTTAATAAAATTAAGTAG T T T T T TAAGT T T GT GTAAATATAAAATAAAAAAAATAAA AAGTGTGGAAGAGGGGTTATAGGGAGTGATTGTGGAAGA GGTGGATGAAGAAAGAGAAAAGCTGACGTGACAGTGTGG AAGAGGGTAAGGATGAGGTGCTATAGGGAGAGGTCTTAT TGAGTTATAATGATGTCAATGGCTTAATAACTTAATGAC ATTTTGGTGATGCGTAAGACCTTAAGACCAGAAAGTCTA AGTTTGAATCTTATAAAATAGGTTTTTTTCTATTTTCCA AATTTATTGAGTTTTCTCATGAGTTCATGTATGAGCATT ATTGCATAGTGAAAATATGGTCAGATGGTTTCATCGATG ACAAGCTAATTTTTAAGAAAGATATATTACTTTTCTTTT TAACTTGGGAAAATCATAAAAGTGAAATCATCGTTTTAA CTTTTTACGAGCATGGTACTCGCGTAATGCAGCGGCGGT GGTATAGAAGACGGTCTAATGGTGGCAGTGTCAAGTGGT GTAGGTCTATGTGCACCGAAACTCCAAACTGACATAGCC GTACCCATTTCCGAAACTCCATGGAAACGTTTTCTCTTA CGAAACACGTATGAAACATTCCCTAAAATTTTCTATAGA TTAAACGTTTCTTTGAAGTTTCCATACGGTTTCTAATTA ATATCAAGGTTTTAAAGGACTTTTTCGAATCCCCAAACC CAAACATGTTATATTATATACAATTTGATCAACATTAAA TTTTTTATATTACAAAGCCATTATTAAACACTAAACATT CAATGAGTGATCACTAATCAAACATGTATTATAAAGTTC TACATATATAATTATACATAATCTCTCAAGTCTCAAATC TCCTTTATGAAAAAATTGATATAATTTATATTTGTATAT TTTTTTTATTGTTGTACCCGTATCCTGGATTTTTTAGTT TTACTGTTCCCCGTTCCCGTATTGTTCCCGTACCCTTTT CCCGTACCTGTTTCGGTGCTACATAGGTGTAGGTTGATG TAATTGTGAGAGTGAAAATTTTTAGAAGACAAGAGTTTA AAGTGTTAATTAGTAAAATAAAAGTTTAGAATGTAAATT AATTCATTAAGGTCAAATTTGGTATTTTATAAAACTCTT TTCATAATGGGTGTTTATTAAGAGACAATTTAGTAATTT TATATGTGACATATGAGTAACTATTTTTATTTTGAGAGG GGTGCATAATTTTTATTCGAAGAGTACGGATAAAAGTCA ATAAATTACGAGCAGTGAAGTATCCCAGACACCCCTTGC AAGGTAATTTTTTAAAATTTTATTCATGGAGGTTTGGTA GGAAGTGGTGGTGGTGGTGGTTGGTATGAAATTTTGTTT TTGACCTTCTTCAAACATCCACCTACTACTGACCCCTCC CTTCAAACCCAACCCAAAATCCAAATCATTAAATCCTTC AAACCCACTGTGTGTTTTGTGTGAAATTTCACACACAAC AAACAATGGCAGCTACTCACATTAACACCACCAACATTG CCCACAATCTCCAAGCTACCACCAGTCTTTCCAAAACCC AAACCCCATCAATAAAGTCACAACCTTTTTTATCTTTTG GGCCAAAACACAAAAACCCGATTGCCCATTTCTCTGTTT CTTCTAATAATAATAGAAATCTTGGAAAAAAATGTTTAA TAGTTTCTGCCGTTGCCACCACCGAGAAACCGTCAACGG TGCCGGAAATTGTGTTACAACCCATTAAAGAAATCTCGG GTACGGTTAATTTACCCGGGTCCAAGTCGTTGTCTAATC GGATCCTCCTCCTTGCTGCGCTTGCTGAGGTATAGTTTA ATTTGGTAATAATGTTTGACCTTTAAAATTTGACATTTG GGCTACATGATTGATATGGGTCTTGAATGAATTGTGTTA TAAAATTTGGGAAGTTAAATGTTAATAATAGTTTAATCC TTTAGAAATTATGAAGTAATGGTTTTAGACCCTGAATTT TTTTTTATTGCATAGGTTAGTCCCTTAGCTAGTTAGCTT 113 WO 2013/039990 PCT/US2012/054789 TTGGTTGACATCTTAGAAAAACCAGTACAGTTTTTATAT TTTAGTCCTTAAGCTTCAATTTTTTGCAATGTATTGCCA TTTGAAATGATCTAGTAAAATGTTCAAAATCAATGAATT GGCGGTTTAAAGATATAATGCTTGGATCAATTGTTATGT AAAGTGTGCTAGGCGGTCAAAAGCGAATCTTGGATCAAG GAAGTCGTAGAATACTATTGATTTCATATTATTGATTTC TTATTATGCATATTTGACATGTGCTTCTAACATCATGGC ATTTGGGATTTATTTCTATATATAAAGCATGACTGTATG GTTATAAAGTTCAAAACTTGTATGGTATAAATATACTCT TCTTACTTCTTAGCAGGAATGTGTTGACTTATAAGCTGA AAACTTTTATAACTCCAATTGTGTGTAGTAATACTTGAA AGTGGCTGAGTTCCTAGGACAGTATTACATGCGAACACT ACAACGTGTTACTAAATTTGAGATAGGTATGATTTGGTT TTGTTGGATACAAAGTCTAGGTCAGTTAACATAGCCAGT TGAGGACGATAGCTTTCTTGTCTTATTTCCTTTTTATAG AGGGTTTGTGTTTCGTGATGGTAATATTGAGTACCACCA TATAGTTCACAAGTCATATAATAAAATCAGAGCAACATT CGAGGAGTCGCCTATATGCATATTATTGCACCATGCTAA AATCCAAGGGCATATTTTGATGCCAATTTGTAATTTATT TCTCAGGGAACGACCATTGTTGACAACTTACTCAACAGT GATGATGTTCATTACATGCTTGGAGCTTTAAGAACTCTA GGGCTAAACGTTGAGGAGGATGTTGCAATTAAAAGGGCA ATTGTGGAAGGTTGTGGCGGTGTGTTTCCTGTGGGTAAA GAAGCTAAAGATGACATACAGCTTTTTCTTGGGAATGCA GGAACTGCTATGCGTCCATTGACTGCCGCAGTTACTGCT GCTGGTGGTAATTCAAGGTATTTGGACGTTGTCATTGAC TCATTGCTATAGTAAATATATGTTGACTTGTGCACACAA GATTTGAAGCATCTTTTAAACATATATGATTAGATACAG AGAACACTGCATGTTGAAAACTTGAAATACAGGACTTTC TTAAAATATTGGGATTTCACATATATGGGTTGAATAGTT GAAATTTCCTCCTTCTACCTTTAACCAATTGTATATTAC TTATTTAAAGTTGTGTTTTAAACATGGCGATATGATTAG ATACAGAGAACACTACTTATTGAAAGGTTTATGTGGTAT AGTATGAATTTTAACCTCAAAAAGGGTATCTCACTATCT CTTCATATAGAAGCACACATCTGATTCTGTTATATCTTT ATGGATCATTTTTTCCAGCTACATACTAGATGGCGTTCC TCGTATGAGAGAGAGACCAATAGGTGATTTGGTCACGGG TCTTAAGCAGCTTGGGGCAGATGTTGACTGTTCTCTCGG GACGAACTGCCCTCCCGTGCGTGTAGTTGGTGGAGGTGG TCTCCCTGGAGGAAAGGTATTGTGTTTTCATTAGTAGTT GTTTTCTATGCAAATAGCAACACACCTTATATATCATCC ATTTATAGCTATTTTTCTAATTGGGGCGTACGTTACTGT AATTTGATCGTCCAACCAGTTGTCATGACCCTCCTTAGC TAAAAT GGAT GAAAGCTGGTC CGACAATT GACCATAATA AATGGGTGTGGGCTATCTTGCTAAATTTAAGTATTTCAC TTAAAATGAGAGTTGGTTTACAGTGTGCATTCAACCTAA TTTTTTTTTTTAACGTCGCATACAACCTAAAATTGAATA ATGTTGTAGACACAAAAGCTCTTAGTGAGCTTTAATAGT AACATTAGAGGTGGTGATATCAATCAAACAATAAGGGAA AAGTAATATGTATAAAAATTAGAATTAAACAAGAAGTTT TAAAAAATAGATCAAATGGTTTGAAAGTCTTCTAAAGTG TAATTTAATGCATAAATCTTCCTAAATTATTTTATTTAA AAACTGTATTGTAATATAATTTTCATCATCATATTTGAC ATTCTATGAAAACAAATATACATTTTGAACAAACAGTGT 114 WO 2013/039990 PCT/US2012/054789 TACGGATCGACCCAGGCAATTCAAAGCTGTCCATTCTAA CCTAAACCAGTTTTCACGGTTACCTCTATTTTCCTGCCT TTCAATTTGCCAGCTACAAGAAGCTTCATTCCACCATAA CGGGTTCACGCTAAAGATGCAAAGAGTCATGATTCGTTA TTTATTATCTTGACTTATTATGATAACAATAGTTTTGGT GTATTTTGATGTCTTCAGGTTAAGTTGTCGGGATCTATT AGTAGTCAATACCTTACTGCTCTGCTTATGGCTTCTCCC CTTGCCCTTGGGGACGTGGAAATTGAAATCATAGATAAA CTAATTTCCATACCATATGTCGAGATGACACTGAAATTA ATGGAACGGTTCGGCGTCTCGGTAGAACATAGTGATAGT TGGGACCAGTTCTTTATTCGAGGCGGCCAAAAGTACAAG TAAGTCTATTTCTTTCTTTTTAAAGTAAAACTGGAATTT AAAAAGGTTGCAGTTTCTACCCTATCTCTTGTAATGGGT TGATTCAGGTTATGTATAATCTCTAATGGGTCAAAGGGG GTAAAATACAAAAAGGTTATTTTGTCACCAAAACGATAT GATGCATATTACCTAGTTTTCTTATTGGAATAGTAAACA TTTTTAATCATTTCAATGTACAACTCTTTTATGTGTCCA CAGAAATTAAACATAGCCCCTAGGACTATGTTCATCATT TCCCTTTATAAACTAGTTGGAGAAAAGTATTTTGGCCAA CCCATTCCGAATTTACACATTTTGGCCTATCACCCAGCC CGTCTGTCCACTCATTTTCAGGGTTTTGTATGGAGACCC GTTTGTTAATTAGTTGGATTAATTATCTTCAGGTCACCT GGAAATGCTTATGTAGAAGGTGATGCGTCAAGTGCGAGT TACTTCTTGGCTGGTGCTGCCATAACCGGAGGCACCATC ACCGTTGAAGGCTGCGGAACAAGTAGTCTGCAGGTGCAC TTTGACCTCCTTTGTTTTTTATTCTTCTCGATTTCAATC AAACGGCTTTACGGTTTTACATTTTAAATGGATTTTGTG GAAACAACGAGTATTAAAAGTTCATCAAAAGATTTTATT ATTATTTTTATGCAACAATTATCAGCATCTGTAGTGAAA TATTCAGAAGTCCGTTTTTAGTTCAAAGTTTTTCTTTTT AACCTTAAAGTCAAAAGTGAGATGGCAAATCTTTTACGT AAAATGATTCAATTGAGGCTGTACTTTGGTCGATTCTGA CTTAATTGGGAACATAGGTTACGTTAGCTATAAGCCTAT AACTATAAGTAAGCATGTGTTTATATGTCACAATGACTT GATTAAAAGTAACCTTATGATTTTCTTAGTATACGTTAG TAATCTAACAGTATCATAATAACGGACAAAAATGTGCTG GTGGATCAGCCCACCCAGCCCGTTAGAACATGACATAAA AATGACCCAACTTGACCTATCACCTAAGCTCATTATAAT ATGTTATCCAACCCACCCTATCTTGGCACCTGTGACCTG TATTCAAATGTATACTGTAAGCAACTTCCTGTTTTTCTT AAACATGTATTCTGTTTTTTCTTTCCAATGAAGGGTGAT GTGAAGTTTGCGGAGGTACTTGGACAAATGGGTGCGGAA GTAACATGGACTGAGAACTCAGTCACAGTTAAGGGCCCA CCAAGGGATTCTTCTGGAAGGAAACATTTACGTGCTGTT GATGTGAACATGAACAAGATGCCTGATGTTGCCATGACT CTTGCTGTGGTCGCTCTTTATGCTGATGGCCCTACAGCC ATTAGAGATGGTATCCTTCCTTTTAATGTGGAAAAAAGT TCAACATGTTTTCACTAAGTTTTCAAAGTAAATAGATAG ATATGACTTCAAAATAACTCTATTGCCATGTTAAATCTT ACACATATTGCAAGCACATTCTAGTGGTGGTTTGGAATG GCATTATGAAATTGAATATCTAAAATATTTAATTTAAAC ATGTTCGGTTTCTGATCATTTAGGGTCAGTTTTAACTGA ATCTCAGAGAAGTCGCGCAAGACATGTCACATATTTGTT TCTCCGAGTCTCAGACAACTGCTTTTTCAAAATGAAAGC 115 WO 2013/039990 PCT/US2012/054789 ATTCTAGAACTATTTTGCTTACAGTTGATTTTCTAATTC TGGGTGTACATAAATCAAGATAATTACTTTTATAAAACA CATTCAAAAAGCCTCCTAGATGCCCCTATTATGAATTTT CTGTTTGCTATACGAGTATCTGCTTTGTTTTTGAAAATG GTTTTTTTGTTTTTTGCCAGTTGCTAGCTGGAGAGTTAA AGAAACCGAAAGGATGATTGCCATTTGCACAGAACTTAG AAAGGTAAAATGATACTTTGTTACTCTGTGATCTATGAT ACTGCTATTGCTTAGAGGTCACTAAAGTGGTAAGGTCAA ATAGGATGGGTTTGAATGGGAACACTTTTCGCCCAAAAC ATATTTAACTAATATAATTTCACTTGTTACTATCTAATT TCATAAATGAAATGATTTAGAATTAGAATGTTTTGGGTG TCTTGCAACCTATTCATTTTAAGCTATTTTAATTGTCTT TTGACCCATTAGAAATATACATAAGAAATATACTTAATC AGTCCTCTATTGTTAATGTTTATCTGGGGTGAAATTTCT TCAGTTGGGAGCAACAGTTGAAGAAGGTCCGGACTATTG TGTGATCACTCCGCCAGAGAAGTTAAACGTGACAGCAAT AGACACATATGATGATCACAGGATGGCCATGGCTTTCTC TCTTGCCGCTTGTGCAGATGTTCCTGTGACCATTAAGGA TCCTTCTTGCACACGTAAGACGTTTCCTGATTACTTTGA AGTTCTTCAAAGATTTGCCAAGCATTAATGTGATTATGG GTAGTGGTTTGCTTTTCTATATGTAATTTTTGTTTCATT TGTAACGAGTAAAATGTGAGTTTTGGGCATAACATATTC TTATGAACTTGTATTCTTTCGTAAGATTTTTTTAGTGTA ATAAAATATTTTGCTATTTCAGTTGATGATTTCTATTAC GGTAATTATGCATCTGACTTCCACTTATACTACGATGTG CATGGCTTTGCGTGAACAGATTGCCAAACAATTTAGTCA TGTGGCTGGTTTGATTGCCCACACTTGTTGAGTTGTTGG CTAGTCGAGTTTGGGTGATCAGAACCCATGTGGCTCGGT TTACACTTTGCGCCCTAACATGTGTGTTTTAAAGGTTAA TTAAACTTATTAAACGGCTTAGTAATTTAAGTCAATAAA ATCATTCAAGTTTCTTTTGTTCCTTTGGAATGATTTAAG CTAATATGAAAAGGGTACTTTTCTTAGACAAAAGTCAAA ATGTGAATATTTACTTTCAAATGAACTCTGGTTATTTAC ACGAGAAATGGGGCATTTTTATTTTGATTTTTTTAAAAA AAGATCTTTCTTATTTGTTATTTATTGTTTAGATAGTAT AACACTTCAAATTAAACTAAATAAAAATAAATACGACGA GTAGTAAACAAGAAGAACCAATAGGAACTTCGGCATTTT ATGAAGCCCAAGGTGCATGAACCTTTAAGAGCATATTCT TTTATCATATTTGTAGGAAATTGTATACATACATACATA CATTATAATATTATATTGTATATAGAGAAGACAAGTTAT ATGTACCATTTAAGGGAAGGCATGGGACAAGGTGCCAAG ATTCATAAACAAAGAGAACATGGATGCCTCGACTTGTGA CTCAAATTGCTCACATGCTTTGCATCAATTTGATGACTT ATATATAATCTTAACGTATTATAATAACCTTAAAAGTGA AATTTAACCCATGCTTATTTTTATACCTTTACAATCTTG ATTATAAGTTAAGATCGAAGCACTTTATGTTTTTTGAAA ATAGTTTTTCCATCCAAAGATCATCTATGTGAGTAGGGA CGAAACCAGAACTTTCACTGTGAGAGGACAAATTTAGAA ATCGTATGTTATACTTAAGATCTTAAGCTTTTTGATGTC TTAAACTAGTCACTTGCAAATGCATCTACTAAATTATGT AAAAGTAGAACCTCACTTCAACTTTGTATTTTTAAAAAA AAATTGGTATTTAAAAAATAAGGCTAGTAAATGTTAATA TTAACTAAAAAAATCCTTTAAAAATAAATGTTTAGCTTC ATTTAACAAATTTGAGATTATGTTTATTCTAAAAATATC 116 WO 2013/039990 PCT/US2012/054789 AGAAAGGTTAAATGCTTTGAAATTTTCTATTACTTTAAT ATTTGTCCATAAATTAAAAAACCTATATATAAAATATAA GGGTTAAAAGGGTT TTCT TTAAAGTAAA-AGGGT CAACAT AACAAT CT CAATAAAGTT T TGAGAT TTAAAAGGAAAAAA TCTAAAAGGCAAGGTAACTTTTGCAAATATGTTGTCTTC CTCCCTTGGTCTCTACAACAGCAA-AGTTACAGCACCATT AAAACACAA-AATGCTTTATCTATTGATTTATCCATTGTT AC TACAATAATAAGCTCT TAATCGTATAAAGCATGGT TC CGTTATCACCTATTTAGGCTTTTCATTCTTTTTTAA-AAA TAAA-AT CCAAGTATAC T TTAAAAT TAAAAAAA-AATAAT T AGAATTTAGCAAA-ATTGGACTGGGGGCAGTTGCCCCCAT T GC C CGCATAC TAAAT C CGTC CCT GTAT GAGAGGTAAAA CATATTTTTCTTGTTATTGCATATATATACTACAAA-AAA AAATTCATTTGTCCACATTTGGTTATCGAAATTGTGAAA AAAT TTAT GAAT TTAAT CACAT TTAAA-AGT GT GTAAAAA TAATTTACATAAAATCACAATACTTATACACTTATAAAT GTGTAAACAAAATATTAACACTTAAAAGTGTGAACAATT GTTAAATATTTTCATACTTAAAAGTGTGAAAGTCAATTT GTGACACATGATTTCTTCACACCCTACGTGTATAA-AGAA AATAAGTGTTACAAATTAACTTTCACACTTTAAGTGTGA ATACCTCTATATTTTTACACACTTAAA-ACTATGAACTTT TCTTTTTCACATGTATAAGTGTGTAAATATTGTGATTTT TTAAATTTCTTCACACTTTGAAATGTAA-ATTATACACAT TTTTAAATGTGATTAA-ATTAACAA-AAATTTTTACACCTT TTAAAAGTATAAAAAACAAGTGTGAGGAAATGATATAT TT GTTGTAGT GATAAAACAAT GTAAATAT CAAT GATATT ATAT CATAT CAC GAACAT GACAT GAAAAAGATAAAT TAT CATATT CTTAATCGGAAT TATAAAAAAAAAAA-AAACAAA AAACAAAA-ACTATTTCTCCCTTACGCAATTTTATTATAA AATTCTTGCAAATACATTAA-ACTATAAA-AATATTGATGA AGAGTCAAGTGACCAGTCCCTTACAATTTAATTAATAAT ATTAA-AATCACTAAATCCCTAGTTTTTAAATGATGCCTT TTCATTTGTAGTCACGTTGTTTGTAAAGGTAATACTTTA TTAAACCTTAAGTTAGCAAA-AAATAATTAAA-ACCATTCT T GT TAT CAT GT CAT TTTC TTAAT TATT CAAAATATAAGC AGTGATATAGAATTGTTAGATTAATTTTGCTATTTTAAT AATAGGAAGAAATGTGTGGTATAA-AATTGTTTTTTTCTT TTTGTCTTTTTAAAAGTGTTCTAA-ATTAATTTTTTCATA TATGTATATATATACAATATTATTTACAACAA-ATATACT TAT T TTAT TACATAATATATATAAT TATATATAACATAT AC TTTT GTAAAT GAT TATAA-AT TAT TGTAAATT TAT TAC TCCTTAGAATAGAATTATTAAGTGAAAA-AATGCGACATA TCATGTGAGAGTTGGATGCCACATTTAGTGTCAAGTTCA CATGATCCTCGAGTTTTGTCCAACCTTCTTTACAGATAA TTCCACAGCTACGCCTTTTAGATACGCATACAAGAGTTT TGTCCAACCTTTTGTGAACAATTTTTCCCCCCCTTTTAA ACGGTAAATACATTTTTATAACATAATGTTAATGGAACT TAAACTCGTAAATTTTTGGTATGTACCACATCAAATATT ATTAGATTATAA-ATGTCATTTAGTTTGCGATAATATATT TTTGGTAACGATCATTCAAA-ATAATTGATAGAAACAAAA ATAAA-ATAA-AATAAAATATTGTGTT TGCTATTC GTGAAA AGAA-ATCCGTGGTTCATTATAAGGTAA-ACAATTATATGT GACTTGACATATGCTATACTTCTTAAATGACTTGGATGT _______________ATTTTGTTATTAGATGAGTTATACTTATACACTTATATG 117 WO 2013/039990 PCT/US2012/054789 CCTTGATAATGCCTTGATATTCATAACACGCAACAAGTT ACTGCTTATAATTTGTGAACTACAAATTTGACTCTCCAA CTCTCCATAGTGATTTAAGAAATTGATTGATGATGAATA TACTTTAAAATTTTACCTATTCATATAGTTATAAGAAAA AAAGAGTAAGTGTTATTTATTTTGAACACAATTTTTTTT TTAATACATAAAATAGTCAA-ATCGATTATTTTCAAGTGT GATATAT GT GCAT GT TAT CT GATT GAC GTAT CAAT GC TA GC TAAT TAAACAT TAAAT TAAATATATAAAC TTATAAAG GACTTAGGAT TGTACTTGCATAATATATATAGT TTTAAA AT GATT CTTC TGATAGTT TTAT CAT GTC CAATT GATT TT GT TAGT TGT TAAATAATAACAATAAT GATAATAATAAAA TAAATAAAATAAATAAATAATAATAATAATAATAATAAT AATAAT GTTTAAGGTTGCAATAACGTGTATAA-AAA-ATTA TATTTATATATCAAAAGTTCTCTCTTGAATTTTATGATA AATGTACATTTTATAACAAAATCTTTATCTTTATGAAAA ATAAA-AAAC TAA-ATT T TGATAT GAT TAAAAAAAAAA-AAA AT GTTT TAGTAT GT TAGGCT CAACT CT CAC GT GACAT CA AAGTCATCAATAACTTAAGTTTATTTTACTGTACGAAGT CCCTGCAGATTGTTAA-AGGTGATCTTAAATTAAAAGCGT AAAAGATCAAGTCTTCCATATAATAACCAATCACACCCT AATTTTTTTACCCCAAA-ATCCTAATAAA-ATTCATGAAGA TCTTGAATATTCTTTCCCTTTTACACCTCCCCCGTTTGA CTTTCTTTAAATGTATACTTGAGCTTGATTAATAGTCCA CC CTAATAAAATCT CAC CATT TT CACAC CACAATTT TAT TTCAAATCTTCTTTCAAACTTTCACTCTCTGTTCTTCAC CATTCTCTCTCCAATCAACTTTTTTCTGCAA-ACCACAAT CACTCC CCT GTT CAAGAAACC TCAAGATT CC GCCAT TAT CAAAAAGTTTTGTTCTTTCTTATCTTGTTTTTACATTCC TTACGCCAAGATTCAAA-ACCCACAAACCTTTCATAA-AAC CCAAGT CACGTATCAAGAATT TAGCACATAAAGTTGGCT TCTTTTTTCATCTTCAAGATTACATCTTTTTATTCAAGA TT TTTGAACAAGAATGAAGCTAATGGATGAAGATGAAAC CC CATCAACT CCTGGTAAATT CAAAATAGATAATAATAA AT CCATATACATT CAT CATAGATT CAGAT TTC TACAT TA CAAATCTTTAGCCAAACTTACATTCTGGTCCTTTGTTTT CTTGGGCTTAATCTTGGTTTTTTTCTTCAATTCCCAATC AT CAT CAT CACAAATT GTAGATCTT TC TAGAAGATCT TT AAAAACAAGTACAT GGGGTGGACCCATAT GGGAAAAACG GGT CAAAT CAT CAGC C CGGAT CC GAACCC GTAAT GGGAT AT CCGTAT TAGTCACAGGTGCAGCC GGGT TTGTAGGGAC ACATGTCAGTATGGCCTTAA-AACGGCGTGGTGATGGTGT TTTAGGTCTTGATAATTTTAATGACTATTATGATCCGTC GC TAAAAAGAGCTAGACAGTC TTTGTTAGATAAAAGT GG GATTTATATAGTTGAAGGTGACTTAAACGATGTCGTTTT GT TAAAAAAGTT GT TTGAAT TAGTC CCAT TTAGT CAT GT TATGCATTTGGCTGCACAAGCTGGTGTTAGATATGCTAT GCAAAACCCTAGTTCTTATATTCATAGTAATATTGCTGG TTTTGTTAATCTGTTAGAAATTTGTAAA-AATGCTGACCC TCAACCTGCTATTGTTTGGGCTTCATCTAGTTCGGTTTA CGGGTTAAATACGAAAGTACCCTTTTCAGAAA-AGGACCG GAC GGAT CAGC C CGC GAGTC T TTAT GCT GC CAC GAAAAA GGCAGGGGAAGAAATCGC GCATACT TATAATCATATATA CGGGCTGTCATTGACAGGGTTGCGTTTTTTTACTGTTTA ______________ ______CGGGCCGTGGGGTAGGCCGGATATGGCGTATTTCTTTTT 118 WO 2013/039990 PCT/US2012/054789 TACCCGAGACATTTTGAAAGGGAAACCGATACCTATATT TGAAGGCCCAAATCATGGAACAGTGGCTAGAGATTTTAC GTATATTGATGATATCGTAAAGGGGTGTTTAGGGGCGTT AGATACTGCAGAAAAGAGTACTGGGAGCGGTGGGAAAAA GCGCGGGCCAGCCCAGTTACGGGTTTTTAATTTGGGCAA TACGTCGCCTGTGCCTGTTTCCGAGCTAGTTGGGATATT GGAAAGGTTGTTGAAGGTTAAGGCGAAACGAATGGTGAT GAAAATGCCACGAAATGGGGATGTGCAGTTTACGCATGC GAATATTAGTTTTGCGAAGAGGGAGTTTGGGTATAAGCC GACAACGGATCTTCAAAGCGGGTTGAAGAAATTTGTGAG ATGGTATGTTAGTTACTATGGAACAGGAAAGAAGACTGA TCACTGATATGATTAAAAAAGATGGAAATTTGTTACCTA AAAAAGACTAAATTTTTTTGTGTTATAATTCTTGTTGAT TTGGATTCTCATATTGATTGTTTTTCATGATATGATGAT GGTAATTGTTTGATACAAACTATATTGAGACTACAAAAG GAATATATTGTTTTAGTTCATTATTTTTGTGTGATGTGT ACTAATAAGTAAGATTTCACATATGTTTTTGTAGGCTTA TTGTTTTGTGGATTTCACGAAAGTTGAGTATAATTCGTT AGATTTCTGATCTTTCTGAACTCGAATCTGGCAACATTA ATCACACGATCAACCACGCCTGCTTGGATACAAGCACCA TACAGAAAGTAGTATCACGTTGAAAATGTCCATTGTTAC CACTGCTTTGGGGTTTTGCCTAATGTCCATGTTTTCATT TTCGTTTTTTATCGATCTTGAACGAATCTAAAGCTAACT TTAGAAAAGAACTGCAGACGCTTAACAAACCAACGTTAG TTGTTCAAATCGGATCAAAATGAACATTACTGGTTTCAA CCCGATTCTTTGTAAACAGACATTGCAAAGAGAGTTGAT CTGTCCAGGTAGCAATTGATATATTTATTATCACTTAAA ATCAATTAAATGATGGTTTAATGTACATATTTTGCAAGT CAATAAATTATGTGACATTGTCACGAGTACACTACCAAA CAGTTGGATTTGATGTTGCTTGTGAGTTGTACATAATGC ATTAAAGTATCTTCATTTGGAGATGTCGATTTCCGTTAT GAAAAACGGTTGGTAAGCTTTTATGTGCAAGTATTTAAG AGATGTTAACACAATCTTTTGAGTTGTCACTTAAGAGTG CTAAAGGAGTTTGTATATGGTGGAACTTGTACTATCAAA TATTAGTTTGTACATATTTTCCCTCAAATTAGTAATTAA ACGTCAATACTTGAATTTGAATACGGGATTTCCTCATCT CCTCTTTAGACAAAAGTTGTGCTTTTGATCTACGTTTGT TGCTTGAAAGTCAAAACCATTTTTTGTTGGAGTTGCTAG GGACTGTTATCATGGGTCGTCATACATAATCAAAAGATT GTGATCTAATCGAGATATAAACTTTGTGGTGTTGAATGA AATGAGCCATTGTTTGTAGAATCTTAGCTTTGTTACCAT TGAGTAAGATCATCGGATAACAATTTTAGCAAATCTTGG CCATCTCATTAATATACGAAATACCATTTTTTATGTAAA ATAATTAGTTACTACGTATATGTACTTATCATACAATGA ACTGACAGTAATTAAGTTATAAATTTGATGTAGGTTTAG GTAAAACCTAAGAAAAGCTATATTGAATGTGCACTTTAT TATGTCTAGTTCATGAACATTAAAGGAGAGTAACAACCC TCGAGCATAAATGTGTGTAAAGAACATGGATGCCAAATT TACTAATTTAATAATCAATACTGTAAAGGATTATTAGTA TTATTATTACTATGGGGATGGGAATATAAGGTTG 63 Conyza Genom 12222 CAATTTAGGAGTTTACTGGTTCTCGAATACCAGCCTATC canadensis ic TTTGTTATTGTTTGATACAAGCCATTGGTTCGTATCAGA AGTTTAGTTGTTTTTTGTCTCAAAAGTTTTCCCCTCATT TTTGAGGTGATTAGGAAGGAAAACTTCTCTTCCCTCTCA 119 WO 2013/039990 PCT/US2012/054789 TCTCCTTTCCTCCCTTAAGTTAACTAGACATTAATGAAT ATTGGGTCATTTTGTTGTTGTGGCTATAAGGAATGACTT GACTTAAAAACTTATAGAAATGCTGTGTTATCCAGTAAG TAATCGTTTTTTTACTATTTGTCTTTTAAGACCATTCAT TAAGCACATAAAACAAACAACAATCCTGCTTAATCGATG TAGACTACATACATGTAGACGGACATTTTATCCATAAAA CAGCTAATTAGTCATACATACCAGTTATATGTTTTACAT CGTGCAGTGTAAAACTTCTGCCTTTACTGCTAAGATTTT TTGTTTACATATATATTAGATATATTAAGGTTTGTATTT TGATGCTAACATTTAACATTACTTTTTTTTTTTATCGGG GAGTGGGTTAAAGTGGTTCTTCTACCTGGTTTTAGTTTT TTAGATGTATATCCAATATTTATTGTGGGTAATTTAAAG TTTTGAAATTTTTGTTTTTTTTTGTGAACAGTATAAAGT TTCTGACTTTTTTGATTTTTTGTGAGGTAAAGTCGTGAA TGTGTAATTTGGTATTTGATTGATATTCTTGATATTGGT ACATAGTGAGGTGCAAGGTGCTGATGGTTTCTTAGACGG GTCATGTTTGTTTTGTGTAAAATACATCTGTTTTTTTCT TTGATAACAAGTTATAGAAGTTGCACCCAAAAATGTTCT TGTTAAAGCGATAAAAATTTGGATAGAAGGTGACGGTTA ATGATTCGATATATTGATTTGAGTTTCCTTTTATCTATT GCATTTTCACAAGTTCAACATTCCACCCTCGATTTTTTG ATGAATCTATGACTGAAGAAAAGGGCGATTGTTGCCTTT GGCAATCAGTTTTGGATTTTATTTTGTCATGGAAAGGGG GTGTTAGTTCCTGAACCTTAGTAGAAGATGATAAGCTAT AGTTTCAATATTGCTTTTCTTTCTTGCATCTGAACTGGT TTTGCATTTTTCAAAGGACTATAAAAGATGCTATTTATC ACCTATGACCTATGTTATAAATAGTAAGGTATTAAACTA TTAATATTGGTATAGTCTTGAGAAATCCATGAATTTCGA TTGAGTTCATAGGACACATCTAACTTATGTTTCTTTACA TTACGATTTACACATCTTGTCTTTGACGTCTGATTTTAA AATAGCGTTTCTATTGACATTATGCATTTCTTTGAGTTC TCTATATAAATTTTTGTAAGCTTTCCATATGTATATACT ATGAATCTGAGTGAACTTATGCTATCAGGGGACTACTGT TGTAGACAACTTGTTAAACAGTGATGATGTTCATTACAT GCTTGGAGCTTTAAGAGCTCTAGGGTTAAATGTTGAAGA AAATAGTGCAATTAAAAGAGCAATCGTAGAAGGTTGTGG TGGTGTATTTCCCGTGGGTAAAGAAGCCAAGGATGAAAT CCAGCTTTTTCTTGGAAATGCAGGAACAGCTATGCGTCC ATTGACTGCTGCCGTTACTGCTGCCGGTGGAAACTCAAG GTATTTTAACTTAGTGTTATATTCTCCTGCATTTTATGT CTGCTTCATCCTCCTACACATACATTTCATGACATGTGT ACCCATTTCTCTCACCTCATCATTTCATTTTTCTATGTG TCACAATTATATGAGTAGGAGGATTCATACTTTCATAGG CATAAATTGTAGGAATCAAATATCGTTTCTTTTTAACCT AACATCTCTTGATTAGCTATTATAATCCGTAGAACGTAT ATTAAAGTTTTTTGTGCCGATATGTAATTTTAAGGTGAA TACACAAATAAAAATTTTACCTTTCTGTTTGTTGCATGT TCTGTACATATAAATTTTTAGTTTTTGTTATATATCTAA GAATCTAAGATCTCTAAATATTCTTCTATTAGTTGACAC AAATTAAGGGATCACATGAACTGAAAACTCAATAGCATC CACTTGTTGATAATGCTGCAATTTAATGTTCCAAAAAAG AAATTATTGCAATTCTTATTATCATTTTATTTATGGGAG ACAGTGAGTATGAATTTGGGAATCGATAATAGAGTTGAC CAACTTGGTGGTGCTGGGTAGCTAAGGTAGTGGGTAAGT 120 WO 2013/039990 PCT/US2012/054789 TACATTGATATGTAATACCCTAACAGTTATGAGTTTTTT CTTCAGCTACATACTAGATGGTGTTCCTCGAATGAGGGA GAGGCCAATTGGTGATCTGGTCACCGGTCTAAAACAGCT TGGTGCAAATGTTGATTGTTCTCTCGGTACAAACTGCCC ACCGGTTCGTGTAGTTGGAAGTGGAGGCCTTCCTGGTGG AAAGGTAATCAACAATAAGATTGCTGCACTTTTAAAGTC GTAAGAATTAATTATTCGGTTCCATATTGGTTTTGGCAA ATTTGGTTATTTAAGAAACTATTAGATAGTAATGAACTT ATAGTTTTTGAATCTTTCCGTAACCTTTTTTCCATGCCC TTCTTATTGCAGGTGAAATTGTCAGGATCTATAAGTAGT GTATACTTGACTTCTTTGCTCATGGCAGCTCCCCTTGCA CTGGGAGACGTAGAGATAGAAATTATAGATAAATTGATC TCTGTGCCATATGTACGGATGACACTGAAGTTGATGCAA CGGTTTGGGGTTTCAGTAGAACACAGTGATACTTTGGAC AGATTCCATGTCCGAGGCGGTCAAAAGTACAAGTAAGTT GATCATTCCATAAAAGTCAATCTTTACGTGAAGATGGGT CAACAGCTATTTTAGTCTGATAAAATCTCTTTAGGTCGC CTGGAAATGCTTATGTGGAAAGTGATGCTTCAAGTGCGA GTTACTTCTTAGCTGGTGCTGCCATCACTGGCGGAACTG TCACCGTGGAAGGTTGCGGGACAAGCAGTTTACAGGTAT TAT C CAT GT GC C CAC CT CAAAGATAT T CAAAAAC TAAAT TGTTTCTCAAGTATATATTCTTCTAGTTAATTGCAAATT TTTTTGCCCCATACGTCTACCCATTCTATAAATTTCGTC CAAAGTTGGTGACTCGGTTCAATCGTGTAATAAGTCTCT TTTTTGTTTTTTAGAATTGACAATTTATGTCAGTTCTTG GTTATATCAACGATGTGGGAGTGTATTGTGCACACATTC TAAAAGAAGGACATTTAGTCTTTTTGCTTTCTTTTTGCC TCAAGATCATCTTCATCTTTTCAAGATACTCTGCACTCA TTTGCATTATCAAAGTTTTGGATGCATTCTGTAACTGTG GTACAAGGAGGGAGACATAATATGTCATTAGTTCTTATT CTTAAGCTCAATGCACACTATCACCTCTTACTTCTTTTT TCTTTCTTTTTTTTTATTAGTTTATTTAAGCTCAATGCA CACTAACACTTCTTCTTTATAACTTCAAGTCATTCATTT TAATTTTTGAAGCTGATGGTTTTTGACATTAAAGATAGA ACTATGTATATACATATGTCATTTCATCTTACCTATTTG CATGTCTTGTTGATCTTTAATCAGGGTGATGTAAAATTT GCTGAGGTCCTTGGACAAATGGGTGCTGAAGTAACCTGG ACAGAGAACTCTGTCACGGTGAAGGGTCCGCCAAGGAAT TCTTCCGGAAGGGGACACTTGCGTCCAGTAGATGTGAAC ATGAACAAAATGCCGGATGTTGCGATGACTCTTGCTGTG GTTGCCCTTTATGCTGATGGCCCCACTGCCATTAGAGAC GGTATGTGTTAGAATTCACCACAGCTTTGTAATGTTAAA TATATGTTAGTTTAGATTAACAAAATGACTATATGATCA CAAAAGGAAACATTTATCTCAAATTTGGAACTAATATAG TATCATACCTATATAGCAATTGTAGTTTCAAAGAAATCC TTAAGGTCGTGTTGTTTATTATACATGACTGGGTATATA TTGTTTTTTGTGCTCAAGCTTTTAAAAATCACATTTGAC TATCCTTTATTGAAAGGTTAATTTTGTTCATGTCTCATT TTAGGCAATTTACTTTTTATCAAGGAAAAAATAGCAATC AATGTCTATGTCGTAGTTTAGGCAATTAAAACCCATCAA TCAAAGTGCTGTTGGTTCAAGGCATATTAGAGATAAATG AGATAATAGTACGTGGATGTCTTTTCAAAAGAAGTACAA ACTTTTTCTTGGGCTCTTTAGTTTTTACTGAAAATACCA AAACTCCTTTAACTGAATTGTCTAAAATAGAAGAAACTGG 121 WO 2013/039990 PCT/US2012/054789 AAATTAGTTGCTATTTTGTGAAAACGAAAAGTAAATCGC CAAAAATTGGAGGTTAAGTATGCTTATATTTTATGTAAT TCATCTTTTTGAAAAATGTAAGAACTTAAATGGAAGTGA ATTGATTTGAAAAATATATATTAAAGCACCACTTATGAA GAAATCTAGAAATTGAGTTTTAGGATCTGTAAAGACATC CTGTATATTGTATGAGAATAGATATATCGTACACCACAA TCCATCATTTTTACTTTTCACACGACAAAGTGAATATGA AAAATGTGAGTTAAAACACTTAAAAGACAGTTTTGGGTG TGCAAAGTAAAATGTAGCACAAATTGGCCCCTTTCTCAT ATTGGGTTTACATATTCTTCTTTACGTATATCCCTATAT TGTTCATTTTGTGGGCCCCATCTCACGTCGGTAAATCAT TAGATGGACTAAATCATATTCTTCATTCCTTATATTGGG CAGTGGCTAGCTGGAGAGTAAAAGAAACGGAAAGGATGA TTGCCATCTGCACAGAACTAAGAAAGGTACAAGTCATTA ACCCATCTTACTCTAAAAAATAGAATGGCCATGAGTACT TTTAAAGTACTCAATGAATCTGCCCATTATTTGTTTAGT GCTAATAGGCCCTTTTGCCCTTGGAACTTTTCAGTTGGG AGCAACAGTCGAAGAAGGTCCAGATTATTGTGTGATCAC TCCACCAGAGAAATTGAATGTGACAGCAATCGACACATA CGATGATCACAGAATGGCCATGGCTTTCTCGCTTGCCGC CTGTGCAGAGGTTCCTGTCACCATTAAGGACCCGGGTTG CACCCGTAAGACCTTCCCCGACTACTTTGAAGTTCTTGA AAGATACACTAAGCATTAAATCACATATAAGATGTTCAG AAAGAAAGGGGTTAGAGGTTTTAAAATGACACCTTTACC CTTCAGTCCTTCACCATTATCTTTCTTCAGAAATGTTTC ACTTACAGAGTTACATCATATGTATATGGGCGACCTGAG CGTATTTTATCTTTTCTTTTCGGTGAGTTTGTAGTTTTT GTTGAGGTGGAATAAGTATTATCTTGAATATTTATGCTA AATTTGGTTAGCAATGTATTATTTTTGATGCATAATGTA TTTGTTATATTATAATGAAAAGTGTTTTTGAATATGGCC AAGATTTGTGAAGGTGAGATGAGTTTTGAACCTTATACT CAGATTTAGCACATGGTGACACTAAATAATTGATCCTTT ATTAGTGCTGAAAATAATTATATGTTAAGAAAGATTGGT TACTAACAAAAGTGGTTATGAGTGAAAGTGGGGTTTAAG TTTGAAGTCATAATTCTCTTGAGATGTTGATTTGAAGTT GAGATGTACGATAGGGGTGTAAAGGCACCTTTGGGATAT AAACAAAATCATGGATTATCTTATTCCTTATACTTCTAT TGTATGTTAATTTTTAATTCAATTTTACTGAATTACTTA AATGATATTTTGAATACTATAAAAGGTTGGTATTACTCC ATATGTTATATGAGTCAGAAATACATTTCGTAATTTGCT CTACATTATCTTAAGTAATATTTCTCTTCTAAATCCAAA TTACTAGTTAATAATATATACTAGTAAAAATGTAGCTAT AAGC C TATAAC TAAAAC CT GAAAAAT GAAAAAGAAAATA AACGCTATATAAATTATGGATTCATGCATGTATCTATTA TATAAATAAAAGAAAATTGTGATGACATCATATTTATTA GAAAAAAATCTACTTGGCATCATTAGACATTCACATATT AATTATTTATTTTTTTTATTTAATTGATTTATGACATCA ATATAAATAAATAGAATTTGATAATTCTATATTAGGAAA TATCATTACTTTTAAAGATTTTGTGGCACTATTACTCTA TTAGACATTTATATAATAATACTTTCTTTTTTTATTTAA TTGATTTATTTATAAATAACTAAACTTTAATTTTTAATT CCCATATTAGAAAATATCTTTAGTTTTAAAGATTTTTGT GTGGTAACGGTTATAACTTAAATGTTCATAGAGTATTAT AAATGAATATGAAAGGTCTTACACATTTTAATTCTTATA 122 WO 2013/039990 PCT/US2012/054789 TAGATTGTATATGTGTTTATAAAAAAAATCACATTTTGT ACAATATCTTGAAGTTTTTCTTGAATTTTATTAAATTTT GTGTTATATATCAATGGGTTGAATGTTAAATAAATTTTC ATTATATAATTTTAGGTAAATTTTACATTATATAATTGT CCTCAATAATTATTTCTTTAGTTTGCCCGCGTAATACGC GGGTTACTTAGCTAGTCAAGTGATAAAGTTCCATTTAGG TAAAAACTAAAAAACATGATAGAAGAGTTTACGTTAATT GTATTATTTATCTAAAAATTCTATTTTTAGTTTCGTAAG TTTAGACTGATCGATCATCTTGCAACTCGATGTTATACA TGGCATTTTATCTTAAAAACTTTTACCCTTGTATTTTTT TTTTTTTTTTTATTGTTTTTCTTTAAACATTCATATCTA TAAT CAT GAAAAGAAATAAAATAAGAAT TAGC GATAAGC CAGATAAATACAAAAGGAGAAAT T TAAGTACAAAT GAAA TTTTATTTCATCTTATGGTACAATGTAATAAAAAGTTAT AGGAAAATTTAACTTCAGTCCTAAGATTGTTGTTAGCGT GAATAAATAATTATACTTTTTATTTTAAAATTAGTTTGA GCGCGTTAAGTCGTTATTGGCAACCCATAGAGTTGTTAT TAGCAATACTAAATTTTTTAATTGTGGATAGCCAAAATT AAATGGATGGGAATTTCCAATGACACACCGGTCTAGTGT TAAGACACATGAGATTTTCTTATAAGTCGGAAGTTCGAG TCTTGTCAAGTACAAGCTTTATTCATATTAATCCCCAAG TAGTCTATGGTGATTTCTTTTGGCATTGTTGCTCGGCAC GGGGTAGTAGGATCCGGTTTAGACAACCGACCAACCGCT TTTTGGGTTAGGACCTCATCATTTGATGGTGAAGGATAT GTTTCTATTCGAAAGTCATTTGTTAAAAAATAATAAAAA TGAATAAATGAACGGAAATTATATGCACCATAACCTTAG AATATACTACCAATATTCCAGGTTTATACTTGTGACTTG CCAACATTTATTGTTGTTGATTGTAATAATGCTCATGTT TCCTTCATTCTTCTTGTATAGTTCCTTGAAAAAATTTCT TGTTGTTGATTGTAACTACAATGATTAATGTAGAAGAAA CAATGGTTAAAAAAAAAATGATATTTGTACCATTTCTTT TGATTGATGTATCATAAATGTGCATTGTTAACTTGTACA GTTAGTTATACAATTTGTACATTATTATACATTAATAAA AAATAGTGATACTAATATCACAAATTAAGCGTTAAAACA GTGTGGGGTGGGGTCTAAAAGACTAACTCAGTAATTTAT GATACTTGGAAATTACTCTTTTCCCAATTAAGCTTGCAA TAAGTTGAAGTTTGGTGGTGTAGTAGCCAGCCTTTTTAC TCTTTTCACATATATACAAACTCACATGATGTAGGTGCT ACCCTAACCAACAAAGTTGGGGAATTTTGACAATAAAGG CATTGAGTGTTTACCTAATTTACAGTCAAAATCTTGACA CATATGACATATATACATTATGGCAAGAAAAAACAAATA TATCCTAAGTTTAGACCAACACCATGTTGTTTTAAAATG ATATTAAATATGTAAGTTATATACATTTCTACTTATTGG TTTTAGTGGTTTATTTCTATATTTGCTATAAAAGTATAA ATTATGGTTTTCCAATATGTTTTGTTTAGAGCTTTAGCC GTTGAATTCATGGAAGAATGACATTTTGGGGTAAGTTAT TGACATGAACGGGCTAACACCTTAGAAAAAATTATTGAA GTATTTATAGATGTGTGTAATAACTCGAAGACATGTATC AAT GT CAATAAATAAGGTAAC GAGAGGAAAAATAAAC T T ATGCATCAACGAATAAATGAATTAGGTATTAAGATATGA TAAAATTGACATGATGTTTACTCTCTTTTCTTTTTTTCC AAAAAAAAAAAATTATCGTTCATCTTGAATTAATTAGTT AGTTTTTTTTTTTTTTTAATTAGTTACTATCACAAAGAG TGTTGAAAAAGCCCTCATTCAAATGATTATTCCAATTCA 123 WO 2013/039990 PCT/US2012/054789 GGAAAATCTTAACACAAAGTACACAACTAAAAAGAGGAC ATTAATCAAAACATCATACTCAAAACATTTGATAGTGAA CAATAGATCAATTGGCTGGAGTTTTTTTTTTTTTTTTTT TATTCCTGATCATAAGTTTGACTCTTCAAAATGACATAC TTTTAGGTTTTCTTTTGACTAACTTATAACAGCTTATGA TTTACATCTTGTAATTTAAAGTATGTGTAGGGATTCACC ATTGTATGATGAGATATCCCCTGATATCAAATAACAACT GACTCTTGAAGAAAAACATACTAATCGAAACCAAAAAAA AAAAAAGAACGCAAAGTTGTAGATGGAGTTGTTCATAAG CTTAAATTCCTCTTGATCCAGTGGGTATCTTTGGTGCAC CACGTGAATGCTGATTTCCTCTTGAAGTTATTAAGCTTG TAATGACAACAACTATGGTTTAAAATGATTCTAGAAGTT AAATACTACGAGGTAGACATTTTTTCATCATTTGTTAGA TAGGCGCATTTTGAAGATCGTTCAAGTCGTCTTCAAAAA CGTCCTTTTTACCTAATGATCAATCAAGGCACGCACCTA GCTATGAGATGAATACGTTGTTGATATTCCGCTTTTCGT TATCACCATTCATCTCGACACGACGTATATATCTATATA TATCCCAACTCTAGATTATATTCATAAGTTCGTATATTG ATGAACTATATATGTGTTATGCACATGCAATGCACCCAT AACATGGAAGAAGAATTATTGCTTTATTCATTCATGTGG AAAATTAGGTATAATGGAATACAAT GAAGGAACATGACA AAGGTGTTACCCAATCACTAAAATTGTGTTTGGCACTAA TGGAGCATTGCAATTGTACTTTCTAAATAATCCATATCT TTAATGGATGGAAAGTTTCATACTTACTTATTACAATCA GTAGATAACCATAAAAATGACATTAATATTGACCTTTAA TTAATAGAATTTTAGAGTTTTTAACAAATCTTTTGTCAT GGACTTCGTATGTAAATTGGGGAAATGCAATTTGTCTTC TATGCAAAATACGAAACCAATTAGATCCAAAAGGTATGA TGATAGTAACATCAATCAATACTCATTTATAAAAGAAGG TTTCCTTTCATTTTCAATTTTTGTGTGCTCTTAATATAA ACCTCACACTAAAAATGACTTATCCCATACTCACATGAC ATGTCTCTTAACTTCCCTTTCAATTAGCTTTTTTTTTCT TCCACTCCTTTATTGCACATCTAAAATTAATTTTTAAAA ATATGACTAATGACTTTTAATCAATTATGGGACTAGTTA ACTTATTAAAAAAGTATCCCCTTATTGAAAGTTACATAG AGAAATGTTTAAATTACTCTCCAAATTTAATTATATAAT ATTTTCATCTAGCACCCCTTAAAATATATTCACATAAAC TATCCCCTTAACATTAATGATTAAGTTACACTATCAATC GTTAATCTTTTAGAATATCTTCATTAACCCTAGCTATAA ATAAATTACTTTTATATCAATTATTTACACCACTTAGCG TCACTTCCACCACCAACAGTTGTCCCATCATCACACCGT CACCGCCACAACCACTGCTGCATTGCGTGGATATAATGC TACTATAAATAATAAATAGTAAGCTTGTAAGGAAAAAGA GTGCCTCAAATACTTTTCTTATAACCCATTTGCAAAAAT AATGGATATCTTAGAATGGCTAAGGAATAACTTATAGCA TATTTTTTAAAAAAAAATAACACTTTATATTTGGAAGTG TTGAAAAATATGTAATATTTTTATTTAACACGCCTTAAA ATATTTTTACATACACTATTCTCTTAATATTAATAATTA AATTACACTATCAATCCTTTATTTTTCTAAAATATCTCC ATTAACCTTTTAAATCAATTATCTACACCACTCGACGTC GCCTTCACTACCAACTATCGCCACCACCACACTGTCATC GTCACGATTACCGCCGCATTACGCAGGTACCATGCTAGT TGAATTTAACTATAATAACTATGAAGTGAAGTTGAATTA ATCAAAGTTATGAAAGACGAAAAAACTTCACTCACTAAA 124 WO 2013/039990 PCT/US2012/054789 AACAATAGAAACCTTATTCTTTTTACAAGTGAATTTTAC CTCAAACGTGTATGATGTATGCAAATCGCACAACGAATG GGTCCCGCACTAAGCGGATCTTAAATAGTTTTTCTCACC ATAACACCTCCTTAATTAGAAAATATCGTCGAGGAGAAC CTACCAAAACTCGAACTCAAGATCTTGGAATAAATTCTC CGGAGGCCCCGCATAGCAGGTTTAGTGAAACACCACTGG CCATAAACGAAATGTAAATAATTTATTTCAAATCGTATA AATTAGAAAAAGCAACACGTTTGGCAAAGTTTCATTTCC CTGGTATTATTTATAAGTTTTCATTAATATTCCAACAAC TAAAAATGGTAATGATGAGGAGTTATCAACGAATGTCAA AACTAAATTCATTTGTATACTCACAATCAAATATTAATC AAAACAAATCTTTAATATTATATATCATCACTAGAAACT AGAAAGTAAACATATAAAATTGAGTGGTAGATTATGAAA TATTATATAATAACGACCAGTTAAAAAGGTTATAACTAA AGGGTTGTGATCAAATGAATCTAATAAAAATAGTGGATA TCAAGGACTTAATCACAGCCATAGGATCAGATGAAATAA ATGGTCCAGATTAGATTTTAAAAAAACACACGGAGGGGT AAAATGGTAAATTTACCTCCTATGCTCACCTAACATTAT ATAACAGATCCAGAATCCCAATCAAAACCCTAAAAATAA AAACAAATCGTGAAATCAAATGGAGATTTCTCCGGCGAT CAAATCGTGAAATCAAACAATCGTGATATCAAATCGTGA TATCAAATCGTGAAATTCCGACTAATAACAATAAAAAAC TCCGGCGATCTGGAATCTGTGAGCGGTGGTACAGCTAAT TGACATAATCTTTGTTGATAATCTTCAATAATTCAGTGA TGGAATCAATAGAAGAATTAGTTATGGAATCAAAAGAAC ATGATGTTTCCGACGACGAGATTATTGAAGATGAAGAAG GGATATTTGCAGACGAGGAAGAAGACAACACAGGTACAT AACCAATCAAAGTTGATTTTACATATAATCGTTGATTTC ACATAGGAATATAGTTTTTCAGCTTGAAGTAACATGCCT AATAAAATCAAAGTTGATTGTACATAGGAATATAGCTTT TCTGCTTACAATCAAAGTTGATTGTACATAGGAATATAG CTTTTATGCTTACAATCAAGGTTGATTCTACATATGCAT GTAAATTTTGTGTTTGAACTAATCTGGCTAATCCAATCA AGTTGATTGTACATAGGAATATAGCTTTTGTACTTACAA TCAAAGCTGATTGTACATAGGAATATAGCTTTTGTGCTT ACAATCAAGGTTGATTGTACATATGCATCTAAATTTTGT GTTTGAACTAACCTGCCTAATCCAATCAAGTTGATTGTA CATAGGAATGTAGCTTTTGTGCTTACAATCAGAGTTGAT TGTACATAGGAATGTTAATTTTCTCCTTGAAGTAACCTG CCTAATCAGATCAAA 64 Conyza cDNA 1882 ATGGAGGTTTGGTAGGAAGTGGTGGTGGTGGTGGTTGGT canadensis ATGAAATTTTGTTTTTGACCTTCTTCAAACATCCACCTA CTACTGACCCCTCCCTTCAAACCCAACCCAAAATCCAAA TCATTAAATCCTTCAAACCCACTGTGTGTTTTGTGTGAA ATTTCACACACAACAAACAATGGCAGCTACTCACATTAA CACCACCAACATTGCCCACAATCTCCAAGCTACCACCAG TCTTTCCAAAACCCAAACCCCATCAATAAAGTCACAACC TTTTTTATCTTTTGGGCCAAAACACAAAAACCCGATTGC CCATTTCTCTGTTTCTTCTAATAATAATAGAAATCTTGG AAAAAATGTTTAATAGTTTCTGCCGTTGCCACCACCGAG AAACCGTCAACGGTGCCGGAAATTGTGTTACAACCCATT AAAGAAATCTCGGGTACGGTTAATTTACCCGGGTCCAAG TCGTTGTCTAATCGGATCCTCCTCCTTGCTGCGCTTGCT GAGGGAACGACCATTGTTGACAACTTACTCAACAGTGAT 125 WO 2013/039990 PCT/US2012/054789 GATGTTCATTACATGCTTGGAGCTTTAAGAACTCTAGGG CTAAACGTTGAGGAGGATGTTGCAATTAAAAGGGCAATT GTGGAAGGTTGTGGCGGTGTGTTTCCTGTGGGTAAAGAA GCTAAAGATGACATACAGCTTTTTCTTGGGAATGCAGGA ACTGCTATGCGTCCATTGACTGCCGCAGTTACTGCTGCT GGTGGTAATTCAAGCTACATACTAGATGGCGTTCCTCGT ATGAGAGAGAGACCAATAGGTGATTTGGTCACGGGTCTT AAGCAGCTTGGGGCAGATGTTGACTGTTCTCTCGGGACG AACTGCCCTCCCGTGCGTGTAGTTGGTGGAGGTGGTCTC CCTGGAGGAAAGGTTAAGTTGTCGGGATCTATTAGTAGT CAATACCTTACTGCTCTGCTTATGGCTTCTCCCCTTGCC CTTGGGGACGTGGAAATTGAAATCATAGATAAACTAATT TCCATACCATATGTCGAGATGACACTGAAATTAATGGAA CGGTTCGGCGTCTCGGTAGAACATAGTGATAGTTGGGAC CAGTTCTTTATTCGAGGCGGCCAAAAGTACAAGTCACCT GGAAATGCTTATGTAGAAGGTGATGCGTCAAGTGCGAGT TACTTCTTGGCTGGTGCTGCCATAACCGGAGGCACCATC ACCGTTGAAGGCTGCGGAACAAGTAGTCTGCAGGGTGAT GTGAAGTTTGCGGAGGTACTTGGACAAATGGGTGCGGAA GTAACATGGACTGAGAACTCAGTCACAGTTAAGGGCCCA CCAAGGGATTCTTCTGGAAGGAAACATTTACGTGCTGTT GATGTGAACATGAACAAGATGCCTGATGTTGCCATGACT CTTGCTGTGGTCGCTCTTTATGCTGATGGCCCTACAGCC ATTAGAGATGTTGCTAGCTGGAGAGTTAAAGAAACCGAA AGGATGATTGCCATTTGCACAGAACTTAGAAAGTTGGGA GCAACAGTTGAAGAAGGTCCGGACTATTGTGTGATCACT CCGCCAGAGAAGTTAAACGTGACAGCAATAGACACATAT GATGATCACAGGATGGCCATGGCTTTCTCTCTTGCCGCT TGTGCAGATGTTCCTGTGACCATTAAGGATCCTTCTTGC ACACGTAAGACGTTTCCTGATTACTTTGAAGTTCTTCAA AGATTTGCCAAGCATTAATGTGATTATGGGTAGTGGTTT GCTTTTCTATATGTAATTTTTGTTTCATTTGTAACGAGT AAAATGTGAGTTTTGGGCATAACATATTCTTATGAACTT GTATTCTTTCGTAAGATTTTTTTAGTGTAATAAAATATT TTGCTATTTC 65 Conyza cDNA 1800 GATTCAAATCCCACATTTACTACGTGTTTTCTCAACCAA canadensis AATCCCCCCCGCCCCCCCACAAAACACACAATGGCAGTT CACATCAACAACTCCAACATACCCATTTTCAACACTTCC AATCTCACAACCCAAAACCCATCTTCAAAGTCATCATCT TTTTTATCTTTTGGATCCAACTTCAAAAACCCATTAAAA AACAATAATAACAATAATTATACCTCTGTTTCTTGTAAT GTGAAAAACAACAAAAACCCATTTAAAGTATCAGCTTTC TCTGCCACTTCCACCAAAGAGAAGCCATCTAAAGCTCCA GAAGAAATTGTGTTGAAACCCATTCAAGAAATTTCGGGT ACGGTCCATTTACCCGGATCCAAGTCTTTATCTAATCGG ATCCTCCTCCTTGCTGCCCTGTCTGAGGGGACTACTGTT GTAGACAACTTGTTAAACAGTGATGATGTTCATTACATG CTTGGAGCTTTAAGAGCTCTAGGGTTAAATGTTGAAGAA AATAGTGCAATTAAAAGAGCAATCGTAGAAGGTTGTGGT GGTGTATTTCCCGTGGGTAAAGAAGCCAAGGATGAAATC CAGCTTTTTCTTGGAAATGCAGGAACAGCTATGCGTCCA TTGACTGCTGCCGTTACTGCTGCCGGTGGAAACTCAAGC TACATACTAGATGGTGTTCCTCGAATGAGGGAGAGGCCA ATTGGTGATCTGGTCACCGGTCTAAAACAACTTGGTGCA 126 WO 2013/039990 PCT/US2012/054789 AATGTTGATTGTTCTCTCGGTACAAACTGCCCACCAGTT CGTGTAGTTGGAAGTGGAGGCCTTCCTGGTGGAAAGGTG AAATTGTCAGGATCTATAAGTAGCCAATACTTGACTTCT TTGCTCATGGCAGCTCCCCTTGCACTGGGAGACGTAGAG ATAGAAATTATAGATAAATTGATCTCTGTGCCATATGTA CGGATGACACTGAAGTTGATGCAACGGTTTGGGGTTTCA GTAGAACACAGTGATACTTTGGACAGATTCCATGTCCGA GGCGGTCAAAAGTACAAGTCACCTGGAAATGCTTATGTG GAAGGTGATGCTTCAAGTGCGAGTTACTTCTTAGCTGGT GCTGCCATCACTGGCGGAACTGTCACCGTGGAAGGTTGC GGGACAAGCAGTTTACAGGGTGATGTAAAATTTGCTGAG GTCCTTGGACAAATGGGTGCTGAAGTAACCTGGACAGAG AACTCTGTCACGGTGAAGGGTCCGCCAAGGAATTCTTCC GGAAGGGGACACTTGCGTCCAGTAGATGTGAACATGAAC AAAATGCCAGATGTTGCGATGACTCTTGCTGTGGTTGCC CTTTATGCTGATGGTCCCCACTGCCATTAGAGACGTGGC TAGCTGGAGAGTAAAAGAAACGGAAAGGATGATTGCCAT CTGCACAGAACTAAGAAAGTTGGGAGCAACAGTCGAAGA AGGTCCAGATTATTGTGTGATCACTCCACCAGAGAAATT GAATGTGACAGCAATCGACACATACGATGATCACAGAAT GGCCATGGCTTTCTCGCTTGCCGCCTGTGCAGAGGTTCC TGTCACCATTAAGGACCCGGGTTGCACCCGTAAGACCTT CCCCGACTACTTTGAAGTTCTTGAAAGATACACTAAGCA TTAAATCACATATAAGATGTTCAGAAAGAAAGGGGTTAG AGGTTTTAAAATGACACCTTTACCCTTCAGTCCTTCACC ATTATCTTTCTTCAGAAATGTTTCACTTACAGAGTTACA TCATATGTATATGGGCGACCTGAGCGTATTTTATCTTTT CTTTTC 66 Conyza cDNA 1730 ATGGCAGTTCACATCAACAACTCCAACATACCCATTTTC canadensis AACACTTCCAATCTCACAACCCAAAACCCATCTTCAAAG TCATCATCTTTTTTATCTTTTGGGTCCAACTTCAAAAAC CCATTAAGAAACAATAATAACAATAATTATACCTCTGTT TCTTGTAATGTGAAAAACAACAAAAACCCATTTAAAGTA TCAGCTTTCTCTGCCACTTCCACCAAAGAGAAGCCATCT AAAGCTCCAGAAGAAATTGTGTTGAAACCCATTCAAGAA ATTTCGGGTACGGTCCATTTACCCGGATCCAAGTCTTTG TCTAATCGGATCCTCCTTCTTGCTGCCCTGTCTGAGGGG ACTACTGTTGTAGACAACTTGTTAAACAGTGATGATGTT CATTACATGCTTGGAGCTTTAAGAGCTCTAGGGTTAAAT GTTGAAGAAAATAGTGCAATTAAAAGAGCAATCGTAGAA GGTTGTGGTGGTGTATTTCCCGTGGGTAAAGAAGCCAAG GATGAAATCCAGCTTTTTCTTGGAAATGCAGGAACAGCT ATGCGTCCATTGACTGCTGCCGTTACTGCTGCCGGTGGA AACTCAAGCTACATACTAGATGGTGTTCCTCGAATGAGG GAGAGGCCAATTGGTGATCTGGTCACCGGTCTAAAACAG CTTGGTGCAAATGTTGATTGTTCTCTCGGTACAAACTGC CCACCGGTTCGTGTAGTTGGAAGTGGAGGCCTTCCTGGT GGAAAGGTGAAATTGTCAGGATCTATAAGTAGCCAATAC TTGACTTCTTTGCTTATGGCGGCTCCCCTTGCACTGGGA GACGTAGAGATAGAAATTATAGATAAATTGATCTCTGTG CCATATGTACGGATGACACTGAAGTTGATGCAACGGTTT GGGGTTTCAGTAGAACACAGTGATACTTTGGACAGATTC CATGTCCGAGGCGGTCAAAAGTACAAGTCACCTGGAAAT GCTTATGTGGAAGGTGATGCTTCAAGTGCGAGTTACTTC 127 WO 2013/039990 PCT/US2012/054789 TTAGCTGGTGCTGCCATCACTGGCGGAACTGTCACCGTG GAAGGTTGCGGGACAAGCAGTTTACAGGGTGATGTAAAA TTTGCTGAGGTCCTTGGACAAATGGGTGCTGAAGTAACC TGGACAGAGAACTCTGTCACGGTGAAGGGTCCGCCAAGG AATTCTTCCGGAAGGGGACACTTGCGTCCAGTAGATGTG AACATGAACAAAATGCCGGATGTTGCGATGACTCTTGCT GTGGTTGCCCTTTATGCTGATGGCCCCACTGCCATTAGA GACGTGGCTAGCTGGAGAGTAAAAGAAACGGAAAGGATG ATTGCCATCTGCACAGAACTAAGAAAGTTGGGAGCAACA GTCGAAGAAGGTCCAGATTATTGTGTGATCACTCCACCA GAGAAATTGAATGTGACAGCAATCGACACATACGATGAT CACAGAATGGCCATGGCTTTCTCGCTTGCCGCCTGTGCA GAGGTTCCTGTCACCATTAAGGACCCGGGTTGCACCCGT AAGACCTTCCCCGACTACTTTGAAGTTCTTGAAAGATAC ACTAAGCATTAAATCACATATAAGATGTTCAGAAAGAAA GGGGTTAGAGGTTTTAAAATGACACCTTTACCCTTCAGT CCTTCACCATTATCTTTCTTCAGAAATGTTTCACTTACA GAGTTACATCATATGTATATGGGCGACCTGAGCGTATTT TATCTTTTCTTTTC 67 Conyza Genom 7954 GTGTTTTCTCAACCAAAATCCCCCCCGCCCCCCCACAAA canadensis ic ACACACAATGGCAGTTCACATCAACAACTCCAACATACC CATTTTCAACACTTCCAATCTCACAACCCAAAACCCATC TTCAAAGTCATCATCTTTTTTATCTTTTGGATCCAACTT CAAAAACCCATTAAAAAACAATAATAACAATAATTATAC CTCTGTTTCTTGTAATGTGAAAAACAACAAAAACCCATT TAAAGTATCAGCTTTCTCTGCCACTTCCACCAAAGAGAA GCCATCTAAAGCTCCAGAAGAAATTGTGTTGAAACCCAT TCAAGAAATTTCGGGTACGGTCCATTTACCCGGATCCAA GTCTTTGTCTAATCGGATCCTCCTTCTTGCTGCCCTGTC TGAGGTATCTTTTATAAATTATGTTTTGAATATTTGAAT TTAATTAGTGTTTTGATTGATTGACTAGAATTTGATTAT TATTAAGATATAGGAAAAGATATGTACATTAGTTTTTGA CTGAATGTGAAAAATGTCTTAATGTAGTAACTCACAAAG TTTTGTTTGTGATCTATAAGTTTACTTTATAAGGTTACT CTATGGGAAAAGGTTACGTAGATTTTGGTTTTCTTTGAC CTCTGTAGTTGGTATGGCCATGAGAAGAAGTAGGCCTAA AAAGAGCTTTGCTTGTGAGAGGACATGACCATACTTAGA GGACTAGGATTAGTTTAGAGGAATATGGTAGATCAGTAA TCCTTTTAGGTATTTTAGGGGTAGTCTATATACTTATAT GTAGGAAGGTCAGGCATGATACCTTTCTTATATGCTCGT ATACTCGTAATTGTTGCTCTCAGTCCATTTGCTTGGTTT TATGCAAACGGTTATGTTTATTATGTTTTTATACTGATG TCTAATATGTTCAAATGTCCTATCTACTATGTATTGTCC ATTTTGCGCTAAAGTGTCCTACGTGGTATGTTTGCTACT CCCCTTTACTCTTAACGTAGGCAGCTCATACCCGACCGA CAAGTATGGTTTGCTTAACTCTTTACACTCTCCTACTTT TGCATCATATGGCCGGAGGTCCTTATGGAAGCAGTCTCT CTACCTTTGGGTAGAGGCAAGATTGTCTACATCTCACCT CCCCCATACCCTGCTCACTGTGTTGTTTAGTTTATTTAA AGGTGGAAAGGAAAGGAGATGAGAGGAGAAATATATAAG ATGCATTCTTAAGATTTTTTTAAGTGTGGAAAGGGAAGG AGTAGAAAGGATTAGAGGGGGAAGTTGATATGGATCTGC GGGAAGTTTATATTATTTAGTAATATAATATTAATTTTA TTATTATTATGATTAGGAAAGTATTGTCTTTACTTAGAT 128 WO 2013/039990 PCT/US2012/054789 ATCTTATGATRTCTTTTATATTATTTAGTTAGCTTGATC ATCAAGCTATAGGATTAGTATAAAAAGAATATTAGGGTT GTAATTCTAAAGTATGAAATATTAATCAGAAGTTTATTG TTCTTGTTTAATCAATTTAGGAGTTTACTGGTTCTCGAA TACCAGCCTATCTTTGTTATTGTTCTTATCATTTGATAC AAGCCATTGGTTCGTATCAATTGGTATCAGAGCATCGAT CTTGCAACCTGTGCTTTTCTTCAACTATGGAATCAAGGA CGATCATTGATGTTGATGCTGATGTACAGCAATACCGTG AATCTACTGAGGCTTGGGTGGACATAATGCATGCTCGGA TCAATCGTTTTCAAGCAGCCACCGCGCGATCTCAGTTGG CCACTCAACAATTTCACTTGAGGTTTACAACTAGGCTGG ATAAACTTGAACCAGTTGTAGTTGGGACACAGCAGAAGT TGGATGCATTGGCGGCAGTGGCAAACCAGCCTCTACCCC AGCAACCGATGATTCAGGAAGTTGTCATACCAACAGTCC CTACAACTTCACCAAAAACAAATCAGTTTGGGTTGAAGC AATCGAAGGTTTCACAAGCAGGGTATCCTTATCCCAGAC ACCTTCAGATCTTGCAAGGAATAATCATCCTGATGTGAA CCAAGAACGAGGAGCTGGACTAACATTCAAGGACATAAG CAATGCTTATGAAGATCTGGCAGGCGATGAAAAGCGATC CATATATGACATGAATGGGGAGAATGGGCTTAAAGGTAC ATGTTTTGGTTTAAGGAATTGTGCAAAAGCTGATGAACT TTCTGGTTTGATACATATGATTGAGTTTGTTAAACAACT TCGATATGATCAGCAAGCTATGGAGTTTCAAGTCAGAAT TTGGGATCCTGGAATTACTCGAAGGAACAATTTAAAGCA ACACCTTGAGGACAAGGTGTTTTTGGGGTGGGAGTAATG ATATGGATCTGCTGGAAGTTTATATTATTTAGTATTATA ATATTAATTTTATTATTAATATGATTAGGAAAGTATTGT CTTTACTTAGATATCTTATGATGTCTTTTATATTATTTA GTTAGCTTGATCATCTAGCTATAGGATTAGTATAAAAAG AATATTAGGGTTGTAATTCTAAAGTATGAAATATTAATC AGAAGTTTATTGTTCTTGTTTAATCAATTTAGGAGTTTA CTGGTTCTCGAATACCAGCCTATCTTTGTTATTGTTTGA TACAAGCCATTGGTTCGTATCAGAAGTTTAGTTGTTTTT TGTCTCAAAAGTTTTCCCCTCATTTTTGAGGTGATTAGG AAGGAAAACTTCTCTTCCCTCTCATCTCCTTTCCTCCCT TAAGTTAACTAGACATTAATGAATATTGGGTCATTTTGT TGTTGTGGCTATAAGGAATGACTTGACTTAAAAACTTAT AGAAATGCTGTGTTATCCAGTAAGTAATCGTTTTTTTAC TATTTGTCTTTTAAGACCATTCATTAAGCACATAAAACA AACAACAATCCTGCTTAATCGATGTAGACTACATACATG TAGACGGACATTTTATCCATAAACAGCTAATTAGTCATA CATAGCCAGTTATATGTTTTACATCGTGCAGTGTAAAAC TTCTGCCTTTACTGCTAAGATTTTTTGTTTACATATATA TTAGATATATTAAGGTTTGTATTTTGATGCTAACATTTA ACATTACTTTTTTTTTTTATCGGGGAGTGGGTTAAAGTG GTTCTTCTACCTGGTTTTAGTTTTTTAGATGTATATCCA ATATTTATTGTGGGTAATTTAAAGTTTTGAAATTTTTGT TTTTTTTTGTGAACAGTATAAAGTTTCTGACTTTTTTGA TTTTTTGTGAGGTAAAGTCGTGAATGTGTAATTTGGTAT TTGATTGATATTCTTGATATTGGTACATAGTGAGGTGCA AGGTGCTGATGGTTTCTTAGACGGGTCATGTTTGTTTTG TGTAAAATACATCTGTTTTTTTCTTTGATAACAAGTTAT AGAAGTTGCACCCAAAAATGTTCTTGTTAAAGCGATAAA AATTTGGATAGAAGGTGACGGTTAATGATTCGATATATT 129 WO 2013/039990 PCT/US2012/054789 GATTTGAGTTTCCTTTTATCTATTGCATTTTCACAAGTT CAACATTCCACCCTCGATTTTTTGATGAATCTATGACTG AAGAAAAGGGCGATTGTTGCCTTTGGCAATCAGTTTTGG ATTTTATTTTGTCATGGAAAGGGGGTGTTAGTTCCTGAA CCTTAGTAGAAGATGATAAGCTATAGTTTCAATATTGCT TTTCTTTCTTGCATCTGAACTGGTTTTGCATTTTTCAAA GGACTATAAAAGATGCTATTTATCACCTATGACCTATGT TATAAATAGTAAGGTATTAAACTATTAATATTGGTATAG TCTTGAGAAATCCATGAATTTCGATTGAGTTCATAGGAC ACATCTAACTTATGTTTCTTTACATTACGATTTACACAT CTTGTCTTTGACGTCTGATTTTAAAATAGCGTTTCTATT GACATTATGCATTTCTTTGAGTTCTCTATATAAATTTTT GTAAGCTTTCCATATGTATATACTATGAATCTGAGTGAA CTTATGCTATCAGGGGACTACTGTTGTAGACAACTTGTT AAACAGTGATGATGTTCATTACATGCTTGGAGCTTTAAG AGCTCTAGGGTTAAATGTTGAAGAAAATAGTGCAATTAA AAGAGCAATCGTAGAAGGTTGTGGTGGTGTATTTCCCGT GGGTAAAGAAGCCAAGGATGAAATCCAGCTTTTTCTTGG AAATGCAGGAACAGCTATGCGTCCATTGACTGCTGCCGT TACTGCTGCCGGTGGAAACTCAAGGTATTTTAACTTAGT GTTATATTCTCCTGCATTTTATGTCTGCTTCATCCTCCT ACACATACATTTCATGACATGTGTACCCATTTCTCTCAC CTCATCATTTCATTTTTCTATGTGTCACAATTATATGAG TAGGAGGATTCATACTTTCATAGGCATAAATTGTAGGAA TCAAATATCGTTTCTTTTTAACCTAACATCTCTTGATTA GCTATTATAATCCGTAGAACGTATATTAAAGTTTTTTGT GCCGATATGTAATTTTAAGGTGAATACACAAATAAAAAT TTTACCTTTCTGTTTGTTGCATGTTCTGTACATATAAAT TTTTAGTTTTTGTTATATATCTAAGAATCTAAGATCTCT AAATATTCTTCTATTAGTTGACACAAATTAAGGGATCAC ATGAACTGAAAACTCAATAGCATCCACTTGTTGATAATG CTGCAATTTAATGCCCAAAGAAGAAATTATTGCAATTCT TATTATCATTTTATTTATGGGAGACAGTGAGTATGAATT TGGGAATCGATAATAGAGTTGACCAACTTGGTGGTGCTG GGTAGCTAAGGTAGTGGGTAAGTTACATTGATATGTAAT ACCCTAACAGTTATGAGTTTTTTCTTCAGCTACATACTA GATGGTGTTCCTCGAATGAGGGAGAGGCCAATTGGTGAT CTGGTCACCGGTCTAAAACAGCTTGGTGCAAATGTTGAT TGTTCTCTCGGTACAAACTGCCCACCGGTTCGTGTAGTT GGAAGTGGAGGCCTTCCTGGTGGAAAGGTAATCAACAAT AAGATTGCTGCATTTTAAAGTCGTAAGAATTAATTATTT GGTTCCATATATGATTGGAAAATTTGGTTATTTAAGAAA CTATTAATTAGTAATGAAATTATAGTTTTTGAATCTTTT TGTAATCTTCTTTCCCTGGCCTTCTTATTGCAGGTGAAA TTGTCAGGATCTATAAGTAGCCAATACTTGACTTCTTTG CTTATGGCGGCTCCTCTTGCACTGGGAGACGTAGAGATA GAAATTGTAGATAAATTGATCTCTGTACCATATGTGGAG ATGACACTTAAGTTGATGGAGCGGTTTGGGGTTTCAGTA GAACACAGTGATACTTGGGACAGATTCCATGTCCGAGGC GGTCAAAAGTACAAGTAAGTT GATCATTT CATAAAAGTC AATYTTTACGTGAAGATCGGTCAACATCTATTTTAATCC GATAAAATCTCTTTAGGTCACCTGGAAATGCTTATGTGG AAGGTGATGCTTCAAGTGCGAGTTACTTCTTAGCTGGTG CTGCCATCACTGGCGGAACTGTCACCGTGGAAGGTTGCG 130 WO 2013/039990 PCT/US2012/054789 GGACAAGCAGTTTACAGGTATTATCCATGTGCCCACCTC AAAGATATTCAAAAACTAAATTGTTTCTCAAGTATATAT TCTTCTAGTTAATTGCAAATTTTTTTGCCCCATACGTCT ACCCATTCTATAAATTTCGTCCAAAGTTGGTGACTCGGT TCAATCGTGTAATAAGTCTCTTTTTTGTTTTTTAGAATT GACAATTTATGTCAGTTCTTGGTTATATCAACGATGTGG GGAGTGTATTGTGCACACATTCTAAAAGAAGGACATTTA GTCTTTTTGCTTTCTTTTTGCCTCAAGATCATCTTCATC TTTTCAAGATACTCTGCACTCATTTGCATTATCAAAGTT TTGGATGCATTCTGTAACTGTGGTACAAGGAGGGAGACA TAATATGTCATTAGTTCTTATTCTTAAGCTCAATGCACA CTATCACCTCTTACTTCTTTTTTCTTTCTTTTTTTTTAT TAGTTTATTTAAGCTCAATGCACACTAACACTTCTTCTT TATAACTTCAAGTCATTCATTTTAATTTTTGAAGCTGAT GGTTTTTGACATTAAAGATAGAACTATGTATATACATAT GTCATTTCATCTTACCTATTTGCATGTCTTGTTGATCTT TAATCAGGGTGATGTAAAATTTGCTGAGGTCCTTGGACA AATGGGCGCTGAAGTAACCTGGACAGAGAACTCTGTCAC GGTGAAGGGTCCGCCAAGGAATTCTTCCGGAAGGGGACA CTTGCGTCCAGTAGATGTGAACATGAACAAAATGCCGGA TGTTGCGATGACTCTTGCTGTGGTTGCCCTTTATGCTGA TGGCCCCACTGCCATTAGAGACGGTATGTGTTAGAATTC ACCACAGCTTTGTAATGTTAAATATATGTTAGTTTAGAT TAACAAAAT GAC TATAT GAT CACAAAAGGAAACAT T TAT CTCAAATTTGGAACTAATATAGTATCATACCTATATAGC AATTGTAGTTTCAAAGAAATCCTTAAGGTCGTGTTGTTT ATTATACATGACTGGGTATATATTGTTTTTTGTGCTCAA GCTTTTAAAAATCACATTTGACTATCCTTTATTGAAAGG TTAATTTTGTTCATGTCTCATTTTAGGCAATTTACTTTT TAT CAAGGAAAAAATAGCAAT CAAT GTCTATGGTCGTAG TTTAGGCAATTAAAACCCATCAATCAAAGTGCTGTTGGT TCAAGGCATATTTAGAGATAAATGGAGATAATAGTACGT GGATGTCTTTTCAAAAGAAGTACAAACTTTTTCTTGGGC TCTTTAGTTTTTACTGAAAATACCAAACTCCTTTAACTG AATTGTCTAAAATAGAAGAAACTGGAAATTAGTTGCTAT TTTGTGAAAACGAAAAGTAAATCGCCAAAAATTGGAGGT TAAGTATGCTTATATTTTATGTAATTCATCTTTTTGAAA AATGTAAGAACTTAAATGGAAGTGAATTGATTT GAAAAA TATATATTAAAGCACCACTTATGAAGAAATCTAGAAATT GAGTTTTAGGATCTGTAAAGACATCCTGTATATTGTATG AGAATAGATATATCGTACACCACAATCCATCATTTTTAC TTTTCACACGACAAAGTGAATATGAAAAAATGTGAGTTA AAACACTTAAAAGGCAGTTTTGGGTGTGCAAAGTAAAAT GTAGCACAAATTGGCCCCTTTCTCATATTGGGTTTACAT ATTCTTCTTTACGTATATCCCTATATTGTTCATTTTGTG GGCCCCATCTCACGTCGGTAAATCATTAGATGGACTAAA TCATATTCTTCATTCCTTATATTGGGCAGTGGCTAGCTG GAGAGTAAAAGAAACGGAAAGGATGATTGCCAT CTGCAC AGAACTAAGAAAGGTACAAGTCATTAACCCATCTTACTC TAAAAAATAGAATGGCCATGAGTAC TTTTAAAGTACT CA ATGAATCTGCCCATTATTTGTTTAGTGCTAATAGGCCCT TTTGCCCTTGGAACTTTTCAGTTGGGAGCAACAGTCGAA GAAGGTCCAGATTATTGTGTGATCACTCCACCAGAGAAA TTGAATGTGACAGCAATCGACACATACGATGATCACAGA 131 WO 2013/039990 PCT/US2012/054789 ATGGCCATGGCTTTCTCGCTTGCCGCCTGTGCAGAGGTT CCTGTCACCATTAAGGACCCGGGTTGCACCCGTAAGACC TTCCCCGACTACTTTGAAGTTCTTGAAAGATACACTAAG CATTAAATCACATATAAGATGTTCAGAAAGAAAGGGGTT AGAGGTTTTAAAATGACACCTTTACCCTTCAGTCCTTCA CCATTATCTTTCTTCAGAAATGTTTCACTTACAGAGTTA CATCATATGTATATGGGCGACCTGAGCGTATTTTATC 68 Conyza Genom 6988 GGCTGGTGTCATGGCTTAATAACTGTRATGACATTTTGG canadensis ic TGATGCGTAAGACCTGTAAGCACCAGCACAAGTCTAAGT CTTGAATCTTATACAAATASGTTTTTTTCTATTTTCCAA ATTTATTGAGTTTTCTCRTGAGTTCATGTATGAGCATTA TTGCATAGTGAAAATATGGTCAGATGGTTTCATCGATGA CAAGCTAATTTTTAAGAAAGATATATTACTTTTCTTTTT AACTTCGGGAAAATCATAAAAGTGAAATCATCGTTTTAA CTTTTTACGAGCATGGTACTCGCGTAATGCAGCGGCGGT GGTATAGAAGACGGTCTAATGGTGGCAGTGTCAAGTGGT GTAGGTCTATGTGCACCGAAACTCCAAACTGACATAGCC GTACCCATTTCCGAAACTCCATGGAAACGTTTTCTCTTA CGAAACACGTATGAAACATTCCCTAAAATTTTCTATAGA TTAAACGTTTCTTTGAAGTTTCCATACGGTTTCTAATTA ATATCAAGGTTTTAAAGGACTTTTTCGAATCCCCAAACC CAAACATGTTATATTATATACAATTTGATCAACATTAAA TTTTTTATATTACAAAGCCATTATTAAACACTAAACATT CAATGAGTGATCACTAATCAAACATGTATTATAAAGTTC TACATATATAATTATACATAATCTCTCAAGTCTCAAATC TCCTTTATGAAAAAATTGATATAATTTATATTTGTATAT TTTTTTTATTGTTGTACCCGTATCCTGGATTTTTTAGTT TTACTGTTCCCCGTTCCCGTATTGTTCCCGTACCCTTTT CCCGTACCTGTTTCGGTGCTACATAGGTGTAGGTTGATG TAATTGTGATAGTGAAAAGTTTTAGAAGATAAGAGTTTA AAGTGTTAAGTATTAAAATAAGGGTTTATGGTGTAAATT AATTCATTAAGGGGAAAATTTATAAAACTATTTCTATAG TGGGTTTTTATTAAGAGACAATTTAGTAATTTTATATGT GACATATGAGTAACTATTTTTATTTTGAGAGGGGTGCAT AATTTTTATTCGAAGAGTACGGATAAAAGTCAATAAATT ACGAGCAGTGAAGTATCCCAGACACCCCTTGCAAGGTAA TTTTTTAAAATTTTATTCATGGAGGTTTGGTAGGAAGTG GTGGTGGTGGTGGTTGGTATGAAATTTTGTTTTTGACCT TCTTCAAACATCCACCTACTACTGACCCCTCCCTTCAAA CCCAACCCAAAATCCAAATCATTAAATCCTTCAAACCCA CTGTGTGTTTTGTGTGAAATTTCACACACAACAAACAAT GGCAGCTACTCACATTAACACCACCAACATTGCCCACAA TCTCCAAGCTACCACCAGTCTTTCCAAAACCCAAACCCC ATCAATAAAGTCACAACCTTTTTTATCTTTTGGGCCAAA ACACAAAAACCCGATTGCCCATTTCTCTGTTTCTTCTAA TAATAATAGAAATCTTGGAAAAAAATGTTTAATAGTTTC TGCCGTTGCCACCACCGAGAAACCGTCAACGGTGCCGGA AATTGTGTTACAACCCATTAAAGAAATCTCGGGTACGGT TAATTTACCCGGGTCCAAGTCGTTGTCTAATCGGATCCT CCTCCTTGCTGCGCTTGCTGAGGTATAGTTTAATTTGGT AATAATGTTTGACCTTTAAAATTTGACATTTGGGCTACA TGATTGATATGGGTCTTGAATGAATTGTGTTATAAAATT TGGGAAGTTAAATGTTAATAATAGTTTAATCCTTTAGAA ATTATGAAGTAATGGTTTTAGACCCTGAATTTTTTTTTA 132 WO 2013/039990 PCT/US2012/054789 TTGCATAGGTTAGTCCCTTAGCTAGTTAGCTTTTGGTTG ACATCTTAGAAAAACCAGTACAGTTTTTATATTTTAGTC CTTAAGCTTCAATTTTTTGCAATGTATTGCCATTTGAAA TGATCTAGTAAAATGTTCAAAATCAATGAATTGGCGGTT TAAAGATATAATGCTTGGATCAATTGTTATGTAAAGTGT GCTAGGCGGTCAAAAGCGAATCTTGGATCAAGGAAGTCG TAGAATACTATTGATTTCATATTATTGATTTCTTATTAT GCATATTTGACATGTGCTTCTAACATCATGGCATTTGGG ATTTATTTCTATATATAAAGCATGACTGTATGGTTATAA AGTTCAAAACTTGTATGGTATAAATATACTCTTCTTACT TCTTAGCAGGAATGTGTTGACTTATAAGCTGAAAACTTT TATAACTCCAATTGTGTGTAGTAATACTTGAAAGTGGCT GAGTTCCTAGGACAGTATTACATGCGAACACTACAACGT GTTACTAAATTTGAGATAGGTATGATTTGGTTTTGTTGG ATACAAAGTCTAGGTCAGTTAACATAGCCAGTTGAGGAC GATAGCTTTCTTGTCTTATTTCCTTTTTATAGAGGGTTT GTGTTTCGTGATGGTAATATTGAGTACCACCATATAGTT CACAAGTCATATAATAAAATCAGAGCAACATTCGAGGAG TCGCCTATATGCATATTATTGCACCATGCTAAAATCCAA GGGCATATTTTGATGCCAATTTGTAATTTATTTCTCAGG GAACGACCATTGTTGACAACTTACTCAACAGTGATGATG TTCATTACATGCTTGGAGCTTTAAGAACTCTAGGGCTAA ACGTTGAGGAGGATGTTGCAATTAAAAGGGCAATTGTGG AAGGTTGTGGCGGTGTGTTTCCTGTGGGTAAAGAAGCTA AAGATGACATACAGCTTTTTCTTGGGAATGCAGGAACTG CTATGCGTCCATTGACTGCCGCAGTTACTGCTGCTGGTG GTAATTCAAGGTATTTGGACGTTGTCATTGACTCATTGC TATAGTAAATATATGTTGACTTGTGCACACAAGATTTGA AGCATCTTTTAAACATATATGATTAGATACAGAGAACAC TGCATGTTGAAAACTTGAAATACAGGACTTTCTTAAAAT ATTGGGATTTCACATATATGGGTTGAATAGTTGAAATTT CCTCCTTCTACCTTTAACCAATTGTATATTACTTATTTA AAGTTGTGTTTTAAACATGGCGATATGATTAGATACAGA GAACACTACTTATTGAAAGGTTTATGTGGTATAGTATGA ATTTTAACCTCAAAAAGGGTATCTCACTATCTCTTCATA TAGAAGCACACATCTGATTCTGTTATATCTTTATGGATC ATTTTTTCCAGCTACATACTAGATGGCGTTCCTCGTATG AGAGAGAGACCAATAGGTGATTTGGTCACGGGTCTTAAG CAGCTTGGGGCAGATGTTGACTGTTCTCTCGGGACGAAC TGCCCTCCCGTGCGTGTAGTTGGTGGAGGTGGTCTCCCT GGAGGAAAGGTATTGTGTTTTCATTAGTAGTTGTTTTCT ATGCAAATAGCAACACACCTTATATATCATCCATTTATA GCTATTTTTCTAATTGGGGCGTACGTTACTGTAATTTGA TCGTCCAACCAGTTGTCATGACCCTCCTTAGCTAAAATG GATGAAAGCTGGTCCGACAATTGACCATAATAAATGGGT GTGGGCTATCTTGCTAAATTTAAGTATTTCACTTAAAAT GAGAGTTGGTTTACAGTGTGCATTCAACCTAATTTTTTT TTTTAACGTCGCATACAACCTAAAATTGAATAATGTTGT AGACACAAAAGCTCTTAGTGAGCTTTAATAGTAACATTA GAGGT GGT GA TAT CAAT CAAACAATAAGGGAAAAGTAAT ATGTATAAAAATTAGAATTAAACAAGAAGTTTTAAAAAA TAGATCAAATGGTTTGAAAGTCTTCTAAAGTGTAATTTA ATGCATAAATCTTCCTAAATTATTTTATTTAAAAACTGT ATTGTAATATAATTTTCATCATCATATTTGACATTCTAT 133 WO 2013/039990 PCT/US2012/054789 GAAAACAAATATACATTTTGAACAAACAGTGTTACGGAT CGACCCAGGCAATTCAAAGCTGTCCATTCTAACCTAAAC CAGTTTTCACGGTTACCTCTATTTTCCTGCCTTTCAATT TGCCAGCTACAAGAAGCTTCATTCCACCATAACGGGTTC ACGCTAAAGATGCAAAGAGTCATGATTCGTTATTTATTA TCTTGACTTATTATGATAACAATAGTTTTGGTGTATTTT GATGTCTTCAGGTTAAGTTGTCGGGATCTATTAGTAGTC AATACCTTACTGCTCTGCTTATGGCTTCTCCCCTTGCCC TTGGGGACGTGGAAATTGAAATCATAGATAAACTAATTT CCATACCATATGTCGAGATGACACTGAAATTAATGGAAC GGTTCGGCGTCTCGGTAGAACATAGTGATAGTTGGGACC AGTTCTTTATTCGAGGCGGCCAAAAGTACAAGTAAGTCT ATTTCTTTCTTTTTAAAGTAAAACTGGAATTTAAAAAGG TTGCAGTTTCTACCCTATCTCTTGTAATGGGTTGATTCA GGTTATGTATAATCTCTAATGGGTCAAAGGGGGTAAAAT ACAAAAAGGTTATTTTGTCACCAAAACGATATGATGCAT ATTACCTAGTTTTCTTATTGGAATAGTAAACATTTTTAA TCATTTCAATGTACAACTCTTTTATGTGTCCACAGAAAT TAAACATAGCCCCTAGGACTATGTTCATCATTTCCCTTT ATAAACTAGTTGGAGAAAAGTATTTTGGCCAACCCATTC CGAATTTACACATTTTGGCCTATCACCCAGCCCGTCTGT CCACTCATTTTCAGGGTTTTGTATGGAGACCCGTTTGTT AATTAGTTGGATTAATTATCTTCAGGTCACCTGGAAATG CTTATGTAGAAGGTGATGCGTCAAGTGCGAGTTACTTCT TGGCTGGTGCTGCCATAACCGGAGGCACCATCACCGTTG AAGGCTGCGGAACAAGTAGTCTGCAGGTGCACTTTGACC TCCTTTGTTTTTTATTCTTCTCGATTTCAATCAAACGGC TTTACGGTTTTACATTTTAAATGGATTTTGTGGAAACAA CGAGTATTAAAAGTTCATCAAAAGATTTTATTATTATTT TTATGCAACAATTATCAGCATCTGTAGTGAAATATTCAG AAGTCCGTTTTTAGTTCAAAGTTTTTCTTTTTAACCTTA AAGTCAAAAGTGAGATGGCAAATCTTTTACGTAAAATGA TTCAATTGAGGCTGTACTTTGGTCGATTCTGACTTAATT GGGAACATAGGTTACGTTAGCTATAAGCCTATAACTATA AGTAAGCATGTGTTTATATGTCACAATGACTTGATTAAA AGTAACCTTATGATTTTCTTAGTATACGTTAGTAATCTA ACAGTATCATAATAACGGACAAAAATGTGCTGGTGGATC AGCCCACCCAGCCCGTTAGAACATGACATAAAAATGACC CAACTTGACCTATCACCTAAGCTCATTATAATATGTTAT CCAACCCACCCTATCTTGGCCACCTGTGACCTGTATTCA AATGTATACTGTAAAGCAACTTCCTGTTTTTCTTAAAAC ATGTATTCTGTTTTTTCTTTCCAATGAAAGGGTGATGTG AAGTTTGCGGAGGTACTTGGACAAATGGGTGCGGAAGTA ACATGGACTGAGAACTCAGTCACAGTTAAGGGCCCACCA AGGGATTCTTCTGGAAGGAAACATTTACGTGCTGTTGAT GTGAACATGAACAAGATGCCTGATGTTGCCATGACTCTT GCTGTGGTCGCTCTTTATGCTGATGGCCCTACAGCCATT AGAGATGGTATCCTTCCTTTTAATGTGGAAAAAAGTTCA ACATGTTTTCACTAAGTTTTCAAAGTAAATAGATAGATA TGACTTCAAAATAACTCTATTGCCATGTTAAATCTTACA CATATTGCAAGCACATTCTAGTGGTGGTTTGGAATGGCA TTATGAAATTGAATATCTAAAATATTTAATTTAAACATG TTCGGTTTCTGATCATTTAGGGTCAGTTTTAACTGAATC TCAGAGAAGTCGCGCAAGACATGTCACATATTTGTTTCT 134 WO 2013/039990 PCT/US2012/054789 CCGAGTCTCAGACAACTGCTTTTTCAAAATGAAAGCATT CTAGAACTATTTTGCTTACAGTTGATTTTCTAATTCTGG GTGTACATAAATCAAGATAATTACTTTTATAAAACACAT TCAAAAAGCCTCCTAGATGCCCCTATTATGAATTTTCTG TTTGCTATACGAGTATCTGCTTTGTTTTTGAAAATGGTT TTTTTGTTTTTTGCCAGTTGCTAGCTGGAGAGTTAAAGA AACCGAAAGGATGATTGCCATTTGCACAGAACTTAGAAA GGTAAAATGATACTTTGTTACTCTGTGATCTATGATACT GCTATTGCTTAGAGGTCACTAAAGTGGTAAGGTCAAATA GGATGGGTTTGAATGGGAACACTTTTCGCCCAAAACATA TTTAACTAATATAATTTCACTTGTTACTATCTAATTTCA TAAATGAAATGATTTAGAATTAGAATGTTTTGGGTGTCT TGCAACCTATTCATTTTAAGCTATTTTAATTGTCTTTTG ACCCATTAGAAATATACATAAGAAATATACTTAATCAGT CCTCTATTGTTAATGTTTATCTGGGGTGAAATTTCTTCA GTTGGGAGCAACAGTTGAAGAAGGTCCGGACTATTGTGT GATCACTCCGCCAGAGAAGTTAAACGTGACAGCAATAGA CACATATGATGATCACAGGATGGCCATGGCTTTCTCTCT TGCCGCTTGTGCAGATGTTCCTGTGACCATTAAGGATCC TTCTTGCACACGTAAGACGTTTCCTGATTACTTTGAAGT TCTTCAAAGATTTGCCAAGCATTAATGTGATTATGGGTA GTGGTTTGCTTTTCTATATGTAATTTTTGTTTCATTTGT AACGAGTAAAATGTGAGTTTTGGGCATAACATATTCTTA TGAACTTGTATTCTTTCGTAAGATTTTTTTAGTGTAATA AAATATA 69 Euphorbia cDNAC 1563 ATGGCACAAGTTAGCAAATTCTGCAATGGAGTTCAAAAA heterophyll ontig ACCTCCATTTTCCCCAATTTTCCTAAACCGGAAACCCCC a AAATCGGTGCCTTCGTTTTCAATTAGGTCAAGTTTTAAC GGGTCTCCGATTTCATCGGGTCTAAATCGGCGCCGAACA AAGGGCGATTGTATTGTTGTTAAAGGTAAAGCTAGTTCG TTTAAAGTTTCAGCTTCAGTAGCCACAACAGAGAAACCC TCTACTTCACCGGAGATCGTGCTGCAACCAATTAAAGAA ATCTCCGGCACTGTCACTTTGCCGGGTTCTAAGTCGCTG TCCAATCGGATTCTTCTCCTCGCTGCTTTATCTGAGGGC ACAACTGTTGTGGACAACTTGCTAAACAGCGATGATGTT CATTACATGCTTGGCGCACTTAAAACATTAGGATTACGA GTAGAAGACAATAGTGAACTCAAACAAGCTATTGTGGAA GGTTGTGGCGGTCAATTCCCAGTGGGTAAAGAGTCAAAG AAAGACATTCAACTTTTTCTCGGAAATGCAGGAACTGCA ATGCGTCCTTTGACTGCTGCAGTTACTGCAGCCGGTGGA AATTCTAGCTACATACTTGATGGAGTTCCAAGAATGAGG GAGAGACCAATTGGAGATTTGGTAACCGGTTTGAAGCAG CTTGGTGCTGATGTCACTTGCTCTTCCACAAATTGCCCC CCGGTTCATGTCAATGCAAATGGCGGCCTACCTGGGGGA AAAGTTAAGCTTTCAGGATCAATAAGTAGCCAATACTTG ACTGCTTTGCTCATGGCAGCTCCTTTGGCTCTGGGAGAT GTAGAAATCGAGATTATCGATAAACTGATTTCGATTCCT TACGTTGAGATGACTTTAAAGCTAATGGAACGCTACGGT GTTTCTGTACAACACAGTAATAGCTGGGATCGTTTCTTC ATCCCAGGAGGTCAAAAGTACAAGTCGCCTGGAAATTCT TATGTTGAAGGAGATGCCTCGAGTGCCAGCTACTTTCTA GCCGGAGCAGCAATTACCGGTGGAACTATCACTGTTGAA GGTTGTGGGACTAGCAGTTTGCAGGGAGATGTGAAATTC GCCGAGGTTTTGGAGAAGATGGGAGCTAGAGTTACCTGG 135 WO 2013/039990 PCT/US2012/054789 ACGGAGAACAGTGTAACTGTGACTGGACCACCACGCGAT TCTCCTCGTCAAAAACACTTGCGTGCTATCGATGTGAAT ATGAACAAAATGCCAGATGTTGCTATGACATTAGCTGTG GTTGCACTTTTCGCTGATGGTCCCACTGCCATCAGAGAT GTGGCAAGTTGGAGAGTGAAAGAAACCGAAAGGATGATT GCTGTTTGCACAGAACTCAGGAAGTTAGGAGCAACAGTA GAGGAAGGAGCAGATTACTGTGTGATAACTCCGCCGGAA AAACTAAATATAACGGAGATTGACACTTACGATGATCAC CGAATGGCGATGGCCTTCTCTCTTGCTGCCTGTGGGGAT GTTCCGGTCACTATTAAAGATCCCGGTTGTACTCGAAAA ACTTTCCCTGACTACTTTCAAGTCCTCCAAAGCTTTACC AAG 70 Euphorbia Genom 9336 ATTAATTACTTCAAAATAAGAAAACAACTGACTTCAGTA heterophyll ic ATTATTTTTTCTTAACTTCTATTTTCGTTTTTAGATAGT a ATAGTCAAGCAACACAAATTAGTTCTTCGAGATAGTGTC ATTGATTGATTTTGGGTCTAAACTTTAGTTCCTTCTAAA GCCCAAGCCCAAGCTCAAGCTTGGTTATGGGAAATTTTA CATCCAAGTTCACTTTTTATTTTTTTTTCCTACCTGGTT CATCGGAGCTTTACTCCGACTACATCCAGATCTGACCCG GGTCGCGCACCTGGCTATGATGGGTGAGTCTCCCAATAA GGATTTTTTGCGTTCACCAGGACTCGAACTCGAGACCTT GCTTAAGCAATACCAAGTCGCTTACCACTTGGACCAAAT TCACTTTAACTCGAGATAAATAAAAAATTCACATTGACT CATTAATACACTATTTTTTTTAACCAATTAGTCTTTAAG CTTCTCCAGATTTATTAAATAATTAAAACAATAATCAAT ATGAATGTTTTTTTTATCACGTGTAAAACATAATATAAA ATGGACTTGGAAGACGTGTAGCCTATATCATTTTATAAA AAAAATTATGTATACACTTATTAAGTTGTATGAATATTT TTAAATAGTAAACACTTAGCAATTGATATCTCTAGTTAT AAAGGTTGTCGATTTCCCACCTGATAACATGATTGACAA AAATGTTTGGTCTAATGAACTTTGATACTATAATAAATT GGTGAATATTAGGACTTTATTTTTTATAAGGTAATAGTT ACTTTATTTTTCATTATTGTTGGATTAGTGATGTGGATT TCAAAACAATGGTAGACTAGATGTAGTAAATTACAAACA AAGTTATCATAAAATTTTTAATTGTATTTATTATATTTA TATTATATAATCTCACAAAATATAATTATAAAAGTAGAT ATGCTTATATATCTATAATAAGCACCAAACCTACCCACT TTCCCTCCCTCACCAAACATGCCGTTAATGGACCAAAAT GCTGATTTGGCAAAATCTAATTGGTAAGTTGCTAATCAC ATAATAACAAAATTGACTCTATATCTTCAAAACCTTGGC TATCTACCACGTCCCACTACCATACGCCACTTCTCAATC TTACCAACCCCTTTTTCTTTTTGGCCCCATAATATTCTT AACATTTCAATTTAGCCCACAAACTTTTAGAGCAAGTCA AGTCATTTTTTTAAATTTCATTCGTCAAACTCCATTTTG AGGAATTTCCATTACTTTCATTTTAACTATCATTCTCAT TTTTCATATTAAATTATCAAAAAATAATAATATTTTATT ATTATATTAATTTATGTAGATCATTTATGTTATGTTGTA ATGAACTAATAAAATAATTAAAAACATTAAAATTCAAAC AAAGTAATAAAATAATGATTCCTTGAAATAGAGAATGCC CATATACGAGAAACCCTCGTTTTGAAGAATACCGTATGG AGAATGGTTGGACTTAGGTCATTTTTATTTAGATTAATA CTCAATGTAGTTCAATTTAGTAACCAATAAGAATTGGTA CAAGTGGTAAGCGACTTAGTATCGCTTAGGCAAGGTCTC GAGTTCGAGTCTTGGTGTACGCAAAAAAGTCCTTACTGG 136 WO 2013/039990 PCT/US2012/054789 GAGACTCACCCACCATAACTAGGTGCGCGACCCGGGTCG GATCTGGATGTAGTTGGAGCAAAGCTCCGGTGAACCAGA TGAAAT TAAAAAAAAATGTAATCCAATTCAGTT TAAAAA AACAA-AACTTTTAGTTAATATTTGTTATTGTAATTGAAA ATCAA-ATAATGTTGTGGGTCAAATTTGGAAA-ATTGTGAA AGATGAGTTAGTTGGAAGAATGAA-ACACCTCAATTGTCG TTACAATAACGCCTAAAACCTCACCAATCTCAAATCCAG AGCAGCCATTTTTCTTCTTCCCCGTCGAGACCAGCAAGA AT CAGAGATACACGGAGATTGGTGGAGGGGGAT CCTGTA GCTCTAGTTAAATGGCACAAGTTAGCAA-ATTCTGCAATG GAGTTCAAAAAACCTCCATTTTCCCCAATTTTCCTAAAC C GGAA-ACC C CCAAATC GGT GC CTTC GTTT TCAAT TAGGT CAAGTTTTAACGGGTCTCCGATTTCATCGGGTCTAA-ATC GGCGCC GAACAAAGGGCGATT GTAT TGTT GTTAAAGGTA AAGCTAGTTCGTTTAA-AGTTTCAGCTTCAGTAGCCACAA CAGAGAAACCCTCTACTTCACCGGAGATCGTGCTGCAAC CAATTAAAGAAATCTCCGGCACTGTCACTTTGCCGGGTT CTAAGTCGCTGTCCAATCGGATTCTTCTCCTCGCTGCTT TATCTGAGGTATGAATTGTTCTGGATTTTTCGGCGATTG CATTCTGTGCCGTTGAATTGTAAGCTGCGGTTTTAGTAT AATCATAATTAGAT GAAGCAGAA-AGGAAC TTAGTTCT TT TGCATTTTATGTTCAGATTCACATAGATCACTAACTGTT GGGGAAATCAGGCAATGAAGGCTAGATAAATAT GAAGTT ATATCGAACACTTTGATTGAAACTTATTTAGCTTTCTAC CAAATAATTTATTCGGATAA-AATCAGAA-ATCGACAAGAA CTTAGAACGAATGTTGTTGTGATGTTATGAA-ACAAA-AAA GTCTGTAAAACGTTATATTTGCCAATGCGTTCTCTCTCT ATATATATAGAGAACCGAAATAACC GTCATATGTTAACT GTTTTTGTAGTTATTTTCGTCTAAGTCGCGACATGGTCC AAATCCAAA-ATTCACGAATTTTCCAAGGGAACTTTTGTT GGAAATAAAATTTGCTTCCGAAACACCGAGCTGTCGGCC TGGGGCGCTGCCCCAGGACCCCGCTAGGGGCTGCCGCCC CT TAGGACTC CGCACTC GGGGGC GAT GCC CCC GGACC CC C TAA-AT CGTAAACAGTAC CC GAACAAGT GT GCACTCC GC AC TTTT CCAAACTT GTTT CGGT GAGAC GT TACAAT TACA TT GGACAA-AC TTAGTTAATCCAATTACAC TAAAATAATA ACAACTTTTACTTTAGCTCGACCCCAGTTTGGGGCACTA CC CCCAAA-ATCC GAATAT TGAACTT GAACAA-AGCAT GCA CTCCACACTCTCTTGACTTGTTCAATGAAATATCACAAT CGCACAATTAGTTGATCTAAT TACATTAAAATACTAC TA ACAACACT TAAT CAACAGT CTAT CAT GT TGTT GGTTT TT CT TTGAACTT CT GAAGCAGGATAGATAA-AGATC GTTC CT TCCCACTGATTGATACTATCATTGCATTGACCTTTAAAT TATCTTCTTTTGGTGCATATAGATTACAGATTTAGTTAA ATCACGTAA-AGTTTGGGCTGAATTTTTGTTAA-AATAAAC TTCAAATTTGAAATCTTACTAATTTTTCAGTCCCTAGGT TTCCATATCCCCTTTATTTCTAAA-AGCCGTTGTTTTGTT GGCATGCCTTATAATTGATTTTTCGTTTATTTCTTGCAA TAAACAACTTTAAACTCTGGCCTTGGAAGCTTTTTTACC TGTGTAAAGTAGTGATTCTGAGTGTTCTACATTCAA-AAT TTTGCTTCTCGAGACCATAA-AACGGTGCTTTACATCTAT TGTCCAGGGCACAACTGTTGTGGACAACTTGCTAA-ACAG CGATGATGTTCATTACATGCTTGGCGCACTTAAAACATT ____ ___________ ______AGGATTACGAGTAGAAGACAATAGT GAAC TCAAACAAGC 137 WO 2013/039990 PCT/US2012/054789 TATTGTGGAAGGTTGTGGCGGTCAATTCCCAGTGGGTAA AGAGTCAAAGAAAGACATTCAACTTTTTCTCGGAAATGC AGGAACTGCAATGCGTCCTTTGACTGCTGCAGTTACTGC AGCCGGTGGAAATTCTAGGTTTACTTTTCCCCCTTTTTT TACCCTCTTTAGACATGCCTTGATTTATTGAACAATAAG CACTTATTTTCCACGACTTATGAGATTCTATATGGTTTA ACATGTATCTAATGTGCTTCAGCTACATACTTGATGGAG TTCCAAGAATGAGGGAGAGACCAATTGGAGATTTGGTAA CCGGTTTGAAGCAGCTTGGTGCTGATGTCACTTGCTCTT CCACAAATTGCCCCCCGGTTCATGTCAATGCAAATGGCG GCCTACCTGGGGGAAAAGTATGTATCGATTTGGCTATCT GTTTGCTATTAATTTCCAGAACTTTTCGTGAAAAATGTA ACTTTTCAGAAAAGCAATCCTAAATTGGCCCTATAGTCT TATTAGTAACGGTATCACAATATGTTTCTTCTCTTTTGA ATTGTACCTAATTTTCCGTGTCTTCACTTTAAAGGTTAA GCTTTCAGGATCAATAAGTAGCCAATACTTGACTGCTTT GCTCATGGCAGCTCCTTTGGCTCTGGGAGATGTAGAAAT CGAGATTATCGATAAACTGATTTCGATTCCTTACGTTGA GATGACTTTAAAGCTAATGGAACGCTACGGTGTTTCTGT ACAACACAGTAATAGCTGGGATCGTTTCTTCATCCCAGG AGGTCAAAAGTACAAGTAAGTATTTTTTCTAGATTCACA AATTCAGAAAGCTATTGAAAAAACGAAAGCTGAATTATC GATCGATTAGGTCGCCTGGAAATTCTTATGTTGAAGGAG ATGCCTCGAGTGCCAGCTACTTTCTAGCCGGAGCAGCAA TTACCGGTGGAACTATCACTGTTGAAGGTTGTGGGACTA GCAGTTTGCAGGTAAATCACGGAACTTTTTCGTATTAGA CATTTACATTTTCACATCTGATGTAAATTAATATGAAAA TCTAGGGAGATGTGAAATTCGCCGAGGTTTTGGAGAAGA TGGGAGCTAGAGTTACCTGGACGGAGAACAGTGTAACTG TGACTGGACCACCACGCGATTCTCCTCGTCAAAAACACT TGCGTGCTATCGATGTGAATATGAACAAAATGCCAGATG TTGCTATGACATTAGCTGTGGTTGCACTTTTCGCTGATG GTCCCACTGCCATCAGAGATGGTAATTTACGTTTCTTTT CATGAATTATGCTTCGTATTCTTCAAATAATTCGAAAAG GCAGCCTAACATTTCCATGGATAATGCCGAACTGAATTA CCGAATTTTCGTAAAAAAATTTACCGAACTGAACTGAAT TTCATCTAATAATCAAAATTTTCTTACCAAAAATATTTC GGTTATCCGAACAAAACTAAATTAATTAAAAAATGCAAT TGGGTT TTTAATAAAATGGTT TATAAATGCAATAAAAAA ATATTAATCCATCATGTTGCGAACCAAACATATTAGTTA TCTTATAATAATTCAACCATACATATAAAACAAATCAGA ATACTATTTTAAGAAACCGAATTATCCGAACCAAACTAT GAATTATCCGAACTAAAATCCGAAATATACGAACCGAAT TACATAATTCAGTTCGGAAATTCGGATAAACCCGAATTA TGCACTGCTTTAAATTTAACAATGATTTGGCTGTAAAAT CTAATGACTCAAATGTTACTCGGATCCTAAAATACGAAT TCCCTTTTTTTCCTCTCGATCTTTTACAAGTGATACAGA CATACAAGGGAAAGACGGATCATTTCCTTAGATTTCGTA TGTTTAAAACTTTTAGACTATTTTTGTTTCTGTTTGACA ATTTGTTCGCTACTCTTTATTTCCAGTGGCAAGTTGGAG AGTGAAAGAAACCGAAAGGATGATTGCTGTTTGCACAGA ACTTAGGAAGGTTAGTTTCTGATAAATAAATTTCACTGG GTTTGAATATAGTGAAACAAAATTCGTCGGCTTATCGAT TCTAATTATAATATTATTGATTGTTGGAATTTCAGTTAG 138 WO 2013/039990 PCT/US2012/054789 GAGCAACAGT TGAAGAAGGGGAAGATTAC TGTGTGATAA CT CCAC CC GAGAA-AC TAAATATAAC CGAGATT GACAC CT ATGATGATCACAGAATGGCCATGGCTTTCTCTCTTGCTG CC TGT GGAGAAGTT CC GGT CAC TAT TAAGGATC CT GGAT GCACCCGAAAAACTTTCCCGGACTATTTTGAAGTTCTCC ATAGGTATAC TAAGCAAT GAACAA-AAA-AC CCGAAAA-ACT TGACAATTGATACTAA-AGAGAGAAT TGTT GCTGTAAC CA TTGAATTCTGATAATTTATTCAAGTGAGTTGAAATTTGT TGATGTACCAGACTAGCTTTTTTTCTATCTCAAATGTTG GGTGTTATTGTAGACAATGTATTCTGAATGAATTCGTTT CGTAAT CTTC GAGT TAATAAGCAAT GAAAGGAT GAAT GT TCTATTTAAGCACTGTTTTTTTGGCTACGACTCAATGGA GTTCATTTCAGTTCAACTATGTGTACACCAAA-ATATGTT CTATTCAGTT CAAT TCAGAAAATTGCAATA-AAAAAGAAC AT TGCC TTAATTAATACGGAATATAGGCAAA-AC CCACAT TGAGCCCCTTGCCAACTAAACTTTCAA-ATGTTCTTTAGC TCCCAACTCGGCACTATTGACCTTCGAGGTCCCTCAAGT TGTGGCACAAATGAATCTCCGAGCTCCCTCAAGCTTAAA AT TAGGTATGTAAGCTTGAGGGAGT TAGGTAGT TTTAAG CTTGACGAAATTTGAAGGGTCATTTGTATCAA-ATTGAGG GAGCTCGGAAGGTCATTTGTGCCAACTTGAGGGGATTGA GAGGGT CAAT TGTGTCAAGTT TAGGGGGT TAGGAGTT TC AT CCGAAAGT TT GGGCAC CTT GAGAGT TATTTT TTAT CA TTAATATTTAGTATATTAATTTTAATTGACCATGTAATT GC TAAAATC TATAT TTTT CGC CCAC GACC TC GTAATT TA TAAGGC CAGC CCAGGGTAAGGTGTAAA-AGAGTTAATC TA AAAATAGAATCACATTCTTCGAA-ACCCAATCTCAATCTA ACATTAAATAATGAAGCATGTAACATGTTGCCTTTGTCT ATATGACATAACATTATTGAGGCATATCGCCCTCCTCCT AT TTAT TTTT CT TACACT TTC TCACAT GGAT GC CTAC CT TTGGTTGTTGGATGTGTCTTTTATATATTTCCTTCATAA TTTACACATTACAATATTACATTACATATCAATCAATCT CTTCTAATATAGTACTTTAAGTTGAGAATATTCTCAACT AAATGT GAATAAAACAACAA-ATAAT TGGGTTCT TTCCAT GCTCACTTTGTTAAAA-ACAA-AATTATGATTACTTTGCTT CT TAT CAC CATTT GAT CAAT CACCC CAC TACT TATT CAA TAGTGATAAGGACAAAGT TATAGTTACTTAA-AGTAAC CA TAGAATTTCCCCAAATAATTGTATCAATAGCGAGACTCA ATAGAT TAAT GTTGTATATTATACAAGTAACCATTAAAC TAGGTTTAGTGGTGACGACTTCCTCTAA-AAGTGGAGAAA GAAGCTGGGATCCTGAATTCGAGCCTCATATTTCTCAAA AT TTAAAT GT TTC TAC TACT TAAAAAA-ATAT TAT TACAA GC TATATTAGTTGAGTAC TCTAATT TGCTATACATAAGG TCTAAAAATATTAGATCTAACATTAATGTCGTATGCTTG AAGTATCAACACTCACTTTATACATTATTCAATCACTTG CT GAT TATT GAAGATAGAGAAGACAC TATAAGC TAT TAT AAGGAAGAAAAAGGAAAGGGAPAAGCAAATAATAAAAG GAC CAAT CAAAGAC CTAGAA-AAAGC TAAAAATAGT GCCA AAACATTGTAGTATAGATGCAAATAAAAATAATTTTACT GTTCTATCTTCTGTTCTAAGTAA-AGAAGTAAGCTATTTA TATTTATTAATTGTTTAATTTCACTTTCAGGATATCTTG TAATTGAATTATTAAGAACATAGGCATTGAGTT TAAGCA AT CAAT TATATAAT TAAT GAACAATAATT CTTT TTAAGT _________________GT GATAAGTGGCTTATTTAGT GTAGATAAATGGACAGCA 139 WO 2013/039990 PCT/US2012/054789 AATCCTTTTCAAAGTCACTTGCTTATGTATGAAAATCTT ATATTGTACACTATATAATGAAACCTACCACTAAAGAAG TGACACACACATATTTTAACCTTTATATATTTTTCTATG ATAATTCAATTATAATTCCGACTTTCATAAATATGAAAA ATGGTAGTAGTAATGACAAATTGTCTTAACTTAAATGAT CGGAAGCTAAAATTCTAATTAAGGAAAGTTGAAAACCTT AAATCAAGAATCTTGGAAAGCAAAAAGTAAAATAAAAGT CCAATAATAACCCAATCCCAAAATATATCTCACACACTT CCAAGGTGTGAAAATAACTAATGGTCCCAATACTAAAAT TAAGTTAGATTTTCACTATATAAAGTATGTAATCCTCAA AGTAAGGATTTGATTGGCCAAAATTCATGGTCTCTCATA CCAATCTAATCAAATTTAAAGACATTTTTGACATTTAAT CAATCATATTGCAAAAAAAAAAAAAAAACTAAACCAATA CACCTCCCATTATTGCAAGTGTTTTTTTAAAAAAAGGTG GCATTTTTCCCTCTTCCTAATACTATTAATGCCTTTTGT TTATCAATTTAGTGTTACTCCTAAATTAAGTAGTTAACC TAATTAATTACCCACAATTTCCTATTCCTATCTTTCATA GCCCCTTCTCCACATCATTTGCTAAACAAAAGAAAAAAA AAACCTGTCAGCTTTTATATTTTTATATGAACTAGTGTA GTGCCCGTGCGATGCACGGATAAATTTTAAAAAATATAT TATATTGCAACATAAAACAAAAATATGTTATATCGTGTA TTGAATTAAATTGTGAAAAACCTTTTTATATACAACATT TGCAGATTCATCTATTAATTGTTCATTATCGTTAAGAGA AAAGGGCATGATATCATATAAATCCGTCTTCAATTACAC CATAAGTGGGTTGATATCATTAATCATATTATTTTTTCA CTTCAAAATATGAAAGATATAAATTTCTACAATTACCAT ATGCTTTCCCATCAAAATTTGATGAGGGGAAAAGAGACA AT TATT CT TAAATAAGAAGGAATAAT TAT T GC TAAAAAT T T TAAAAAT T TAAT CT TAAATAGAAT T GTAACCAACATA ATTAAATAAAATAAGAATAACAAATTAAATTTTATAATA GATTTTAGAATTATAATGAGATTTTGATTTGTTTCCATG ATTCACCCTAATTAATTATTTTCCCATAAAAATAATTAT TGATATTAATCATTATCATTTTTCTAAATAAATCTATTT TAGAAATATATTAAAATCAATTTCCTAAAATTCATGAAA AATACCAATTTCTTTATTACTATAAACGACAATTATTAT TATTGTTGTTATTAT 71 Euphorbia Genom 6002 ATTTTCCCCAATTTTCCTAAACCCGAAACCCCCAAATCC heterophyll ic GTTCCTTCGTTTTCAATCAGGTCAAGTTTTAACGGGTCG a CCGGTGTCATTCGGTCTAAATCGGCGCCGGACAAAGGGC GACAGTATTGTAATCAAAGGTAAAGCTAGTTCGTTTAAA GTTTCAGCTTCAGTAGCCACAGCAGAGAAACCCTCTACT TCACCGGAGATAGTGTTGCAACCAATTAAAGAAATCTCC GGCACCGTCACTTTGCCGGGTTCCAAGTCGCTGTCCAAT CGGATTCTTCTCCTTGCTGCTTTATCCGAGGTATGAATT GTTCAGAAATTTTCGGCTATTGCATTCTGTGCCGTTTAA TTGTAAGCTGAGCTTTCGTTATTGTCATGATTGCATTGA CCTTTTGATTTTCTTCTATAGCTGGTTATAGATATCAGA TTTAGCTTAATTATGTAAAGTTTATGCTAATTTTTTTTG AATTAAACTTCAAATTTTGAGCTATAACTTATCTTTTAG TTCATGTGTTTCCCTTGTTCCCTATCTGAAGACTTTTTT TTTGCAACGATAACTTCATAATATGGCCTCCATAGCTCT GTAAAGTAGTGATTTTGAGCGTTTTTTGCTTGAATATTT TGCTTCTCGTAGAATGTTGACTAATAGAACGGTGCGTAA AATGGTTTTTACATCTATTGTTCAGGGCACAACTGTTGT 140 WO 2013/039990 PCT/US2012/054789 GGACAACTTACTAAACAGCGATGATGTTCATTACATGCT TGGTGCACTTAAAACACTCGGACTACGAGTGGAACACAA TAGTGAACTCAAACAAGCTATTGTAGAAGGTTGTGGAGG TCAATTCCCAGTGGGTAAAGAGTCAAAGAAAGATGTCGA ACTTTTTCTCGGAAATGCAGGAACTGCAATGCGTCCATT GACAGCTGCAGTTACTGCAGCCGGTGGAAATTCTAGGTC TTTTTTTACTCCCTTTCTTACCCTCTTTATATAACCCTT GCTTTACAAAACAATCACACTTCTTTTCCACGACTTATG AGGTTCTATATGGTTTAACATGTATCTAATGTGCTTCAG CTACATACTTGATGGGGTTCCAAGAATGAGGGAGAGACC AATCGGGGATTTGGTAACCGGTTTGAAGCAGCTTGGTGC TGATGTCACTTGCTCTTCCACAAATTGCCCACCTGTTCA TGTCAATGCAAATGGCGGCCTACCCGGGGGAAAGGTATG GTACTGTTGTCACGAAAAGTTCCACTTGCAAACTTTTAT AAGAACAAAATATTTTGACATTAGAGAAATGATTTTGAC TATCTGTCTGCTATTAATTTCCGGGTAAATAATTATAAC CTCCCTCAAGTTTGACATAATACGCTACTACCTCATTGG GTTTTAAAAACCTAATATATACCTCCCTATGTTTTATAT TTTCTAATTACTATCTCCCTATACTTTACTTTTATTATA TTGTTAGGCCCCTTTATAGGTTATTATGTCATTATTATA TGGAAAATTAACCAAAATATACATTTATAACAAAACTAT TATTGTTGTGATATTTCTATATTCAATTTTTCTTTGATT TTTCTATTTTATGTATGTTTTTTCTAACACAATCATAAG ACT GGAAT GTAATAAGAT GT TAGAAAATAAGCAAAACAA ACATCTTATTTGTGAAATATCTTCAAAAATCAATACATA TGATCACTAGTTAAGAAAATATTGTAAAAAAGT GTAT GG AACATCAATGATTTTGTGTGAAAATGCTTAACGATTGAT AGAGT GAGGTAGAAATAAGAAAAT GCAAAACATAC GGAG GTATAAATTATGTTTTTAAAACACAGGGAGGTGTTAGTA TATTATGTCAAAACTGAGGGAAGTTGTAATTATTTATCC TTAATTTCCGGAACTTTTCGGGACAGTAGCTTGGAAAAG CACGAAAATGTAACTTTTCGGAAAAACAATCCCAAACTG GCCCACTTATTCAGTAATGTATCACAATATATTTCTTCT TTTTTGAATTCTACCCTAAATTTCCGTGTCTTCACTTTT AGGTTAAGCTTTCGGGATCTATTAGTAGCCAATACTTGA CTGCTTTGCTGATGGCTGCTCCTCTGTCTCTTGGAGACG TAGAAATCGAGATTATCGATAAACTGATTTCAATTCCTT ACGTTGAGATGACTTTAAAGCTAATGGAACGCTACGGTG TTTCTGTACAACACAGTAGTAGCTGGGATCGTTTCTTCA TTCCAGGAGGTCAAAAGTACAAGTACGTATTTTTTGGGT TCAACTTCCAAAACTCCCTTGTGGTTTCCTCATTTTCAA AAAGGCCCTTAGTGTAATTTTTTTTTCAAAAGGGCCCTT GTGGTATAAAAAATTAGCAAAAAAAGAGGAGTCTCTCTC AACAAAGATAGTTGTTTTGACTTGGCAAAGGGTATTTTC AT CAAAC C C CAAAT T T T T CAAAAT T TAAATAAAAAAAT T ATTATATTTCAGATTGTCAACTCAAGGTAACTAACTTTG ATGTGAAAAATAATCCCCTTTTTGCTTATTCTTGATACC ACAAGGACTCTTCTGAAAAAAAGTTACACAAGGGCCTTT TTGTACACGAGTAAAACCACAGGGGGGTTCTTGAAGTTA ACCCTATTTTTTGGATTAGTAAATTCAGAAAGTTTGATT ATGCTGAAGAAACGACAACCTGAAATATCGATCAACTAG GTCTCCCGGAAATTCTTATGTTGAAGGAGATGCCTCAAG TGCCAGCTACTTTCTAGCCGGAGCAGCAATTACCGGTGG AACTATCACTGTTGAAGGTTGTGGGACTAGCAGTTTGCA 141 WO 2013/039990 PCT/US2012/054789 GGTAAATCACGGAACTTTTTCGTATTAGACATTTACATT TTCACATGTGATGTAAATTACGTGTTATATGAAAATCTA GGGAGATGTGAAGTTTGCCGAGGTTTTGGAGAAGATGGG AGCTAAAGTTACCT GGAC GGAGAACAGTGTAAC TGTGAC TGGACCACCACGGAATTCTCCTCATCAA-AAACACTTGCG TGCTATTGATGTGAACATGAACAA-AATGCCAGATGTTGC TATGACATTGGCTGTGGTTGCACTTTTTGCTGATGGCCC GACCGCCATCAGAGACGGTAATTTCCTTTTATTTTCATG AAGGGTAA-ACTTCAAAA-AAGAACCTTTTGGTTTCGCTCA TTTTCAAAACGGGGTCTAAGAATTTTTTTTGTAAA-ATTG GGTTTGTAGTTTCAAAAATTTAGCAAAA-ATGGGCCTTTG GC TTCGAAATAGTGGTGT TACATTGAATATTTATAA-AAA AT TTAACATT CTAATAAT TTAACCT TAT CATT TAAA-AAT TAAATGCTAGAGTTTGAATAATTTTCGGAGATTTTTTTA AGTTTATTATCATAATTTGTTTAA-AAA-ATATATTTGCAC TTGTCAAAATTTTTTACCGATGTGTATTATATTTTGAAT AAT CAT TCC GAAAAAAT TCAGATAAAAACAA-ACAA-AGAT TAACAATTTCCGTGACATGTTTTAATATTGAGTAGCCTT TATTTGCGAATTTTCTGAAACCACGTACCCCGTTTTGAA AAAAA-AAAA-ATTCCTCAGACCCCATTTTGTAA-ATGAGTG AAATCACAAGGTACTTTTTTGAAGTTTACCCTTTCATGA ATTATGCTTCGTATTCTTCAAATAATTCGAAA-AGGCGGC C TAACAT T TCCAT GGACC TGAACTC CATATATAATAC CG AGCAATTTTAACAATGATTCGATTGTAA-AACCTATTGAC TCAAATGTAATTCGGATCCTAAATACGAATTCCCTTTTT CTCTCTCTCGATCTTTCCAGTGGCAAGTTGGAGAGTGAA AGAA-ACCGAAAGGATGATTGCTGTGTGCACGGAACTCAG GAAGGTTAGTTTCTTATAAATAA-ATTTCACTGGATTTGT ATACAGTAA-AACGAAA-ATTTGTCGGCTTATCGACTCTAA TTATAATATTATCAATTGTTGGAAT TTCAGTTAGGAGCA ACAGTT GAAGAAGGGGAAGAT TACT GTGT GATAACTC CA CC CGAGAA-AC TAAAAATAGCT GAGATT GACACT TAT GAC GATCACAGAATGGCCATGGCTTTCTCTCTTGCTGCCTGT GGAGAAGTTCCGGTCACTATCAAGGATCCTGGATGCACT CGAAAAACTTTCCCGGACTACTTTGAAGTTCTCCATAGG TATAC TAAGCAAT GAACAAAAAAC C CGAAAA-AC T TGACA AT TGATAC TAAAGAGAGAATT GTTGCTGCAATCAATGCA ATTCTGATGATTTATTCAAGTAAGTTGATATTTGTTAAT GTACTGGACTAGCCTTTTTTCTTACCTCAAATGTTGGCT GTTATTGTAGACAATGTATTTTGGGTTGAATCCATATTG TAATCTATCGAGTTAATAAGCAATGAA-AGGATGAATGTT CTATTTAAGCCCTGTACTTTTGGACTACAACTCAATGAA GTTCAGTTCAGTTTAGCTACGTGTAGTTATAA-ATTTACT C TAAAATAC GT TC TAT TCAGT TTAATT CAGAA-AATT GTA GTAATTAATACAAAATATAGGCAA-AACCCATAT TGAGCC CCTTGCCACCTAAACTTTCAGATGTCCCTTTAAGCTCCC CCAACTTGGTACATTTGACCTCCGAGCTCCCTCAAGCTT AAAATTAGGCATGAAAGC TTGAGGGATAAAGCT TGAGGG AGCTCGCGTAGTTTTAAGCTCGAAGGAGCTTGAAGGGTC ATTTGTGTCAAACTAGGGGAGTTCGAA-AGGTCATTTGTG CCAACT TGAGGGAGCAGAGAGGGTCAATT GTGT CAAGTT TAGAGGGTTAGGAGGTTCATC CGAAAGTT TGGGCACC CA AGAGGAAAA-AATTGCCAAATT TAGGAGGC TCAATATGGA _______________TTTCGCCTAGAATATACTTAAATATAGATGCATGACTCT 142 WO 2013/039990 PCT/US2012/054789 TATGGTCTATTAATAAATACTATAGTTACAAGTACCGCT TCCTCTTAGGAGAAAACTAATGCATTTTTAAAAGGTTAT GGGCTTGCAAGTATCTTTTCAAAGTTTTAAGGGCAATAA GCGAATGAGATAAGTTGAGGGAGCTAGTTCCATGTAGGG AAACCCTGCCTGTTGAAAATCGTTTGTAAGCCATATGAT AGTACGGTGAAAACAAAATTTTAGCGAAACTCATGTGGA TGGCAAGCAAAGGAAAGGAGAATGACTAAAGGAGGTAAG GTGTAAAAGAGTAAATCTAAAAATAGAATCACATTCTTT AAAAGCCAATCTCAATCTAACATTAAATAATGAAGCATG TAACATGTTGCCTTTGTCCATATGACATAACATTATTAA GGCATGTCGCCCTCCTCCTATTTATTTTTCTTACACTTT CTCACATGGATGCCTACCTTGGTTGTTGGATATGTCTTT TATTTATTTATTTCCTTCTTAATTTACACATTTCACTAT TAAACATCAATCGATCTCTTCTAATATAGTACTTTAAGT TAAGAATATTCTCAATTAAATGTGGAATGAAACAAAAAA TAATTGTATCAATAGCAAGAATAAATAATTATACTTAAA AAACATGTCCCACAAAATTAGATTCAATAGATGTGAAGT CAATATTTTACAAGCAACCACTAAATTAGGTTCAGTGGT CACAACTTCTTTTAAAAGTGGAGAAAGAAGTTGGGGTCC TGAGTTCGAGCCCCATATTCCTCAAAATTTAAATGTTCT TATTACCTAAAAATATATTATTACAAGCTATATTTGTTG AAATCTCTAATTTGCTATACATAAGGTCTAAAAATATTA GATCTAACATTAATGTCGTATGCTTGAACAACATCCACT TTATACATTATTCGATCACTTGCTGATTATTGAAAATAC AAAAGCACTAAAAGCTACTTCCTCCATCTAGATTTAATG GTTTTTTTAGACCTTTTTTCACATCTTTTTTAGTTGTCA ATTCCTATTTACCATGTACTTTTCCAGTCATGCCCCTAT TAATTGCAATTTTGAAAAGCTTTGAGAATGAAATA 72 Euphorbia Genom 5555 ATTCGTGCTGCCATTAAGGAGGCTAAGGCTGTAAAAGAC heterophyll ic AAGCCCACTATGATCAAGGTGAAATGATGCCTCTCTTAC a AGTGTGTTTATATATAGATATAAACAATAGAAGTTTTTA AATGGTGTTTGTACTTGCTTGCAGGTCACTACAACAATT GGTTATGGATCGCCAAACAAGGCAAACTCATACAGTGTA CATGGAAGTGCACTTGGTGCCAAGGAAGTTGATGCTACG AGGGCGAACCTAGGATGGCCCTATGAGCCTTTCCATGTT CCAGAGGATGTTAAGAAGTAAGCCGACACTACTAGCTAG GTTTCCGTCTGTTTTTTTTACCGATTTTGATTTGACTTT GATGACTCTTGTTTCAGGCACTGGAGTCGCCATGCTGCA GAGGGAGCTTCTTATGAAGCTGAATGGAACGCTAAGTTT GCCGAGTACGAGAAGAAATACAAGGAGGAAGCTGCAGAG TTCAAGTCCATCATCACGGGTGAATTACCGGCTGGCTGG GAGAAAGCACTTCCAGTGAGTATCTGCTTCATATTTCTT GCCCCTTTTATCTTTTAGGTGGCGTTTGGGTCTCGGAAT TCCTATTCCGTGGAATAGAAATAGAAGTGTGTGGAAAGA TGTCAAATATAGAAGAGAATTCTAGACGCATGGAAAAGC TTTTCCAAGTTTGTATACATCTCATGGAAAAGCTATTCC TTTGTTTCAAAAAGGAGTAGCTTTTCCTTGAGATGTATA TAAACTAGGAAAAGCTTTTCCATGCGTCAATGGATTCTA GATGATTAATGTGTCATATTTGACATCTTTCCATGCATT TTTACTTCTATTCCATGGAATAGGATTTCTGCTAACCAA ACGAGCCCTTAGAGTTATTACTTAGTGAATTTCCACTTG CATTATCTGAAAACAGACATCTCATATTTTCTTTGTCAA GCTTTATGAGCGTGTTTGGCATCAATGTTTGGCATGAAA TTTAACTCAATTCAAATTATTTTATACCTAAGATTGTAA 143 WO 2013/039990 PCT/US2012/054789 ATATGAAATGAATTCTTTCAAAACAAGATTTCCAACACA CCCCATGACTAATTTCTCCATATGTTTGACCTCATGCAT AATTTGGAACCAATCACTTCAGACAACCCGATACACATT CTTAAGAGTTAGGACAAAACGAACATTGGATTTTCAGAC TTGATAATCTCTTAATCCTTCACTATTGAAATTTTTACA GACATACACCCCAGAGACCCCAGCAGATGCCACCAGAAA TCTATCACAAGCCAATCTAAACGCACTTGCCAAAGTGCT CCCCGGTCTCATCGGTGGCAGTGCAGATCTTGCCTCATC AAACATGACCTTGCTGAAAATGTTCGGCGACTTCCAAAA AGACACTCCAGAAGAAAGAAACGTCCGGTTCGGTGTCAG GGAGCATGCAATGGGCGCCATCTGCAATGGCATAGCTCT CCATAGCCCCGGCTTTATCCCCTACTGTGCAACTTTCTT CGTTTTCACCGACTACATGAGAGCCGCCATGAGGATCTC CGCCTTGTGTGAGGCCGGCGTAATTTACGTCATGACCCA CGACTCCATCGGTCTCGGAGAAGACGGGCCCACCCACCA GCCGATCGAACACCTGGCAAGCTTCCGTGCGATGCCCAA CATCTTGATGCTCCGACCGGCCGACGGAAACGAAACTGC CGGTTCGTACAAGGTTGCTGTCCAAAACCGGAAGAGACC CTCGGTCCTCGCACTTTCTCGACAAAAGCTGCCGAATCT CGCGGGAACCTCGATTGAGGGGGTTGAAAAGGGCGGGTA TACAATTTCAGATAATTCGACCGGGAATAAGCCTGATGT GATTTTGATTGCGACCGGTTCGGAGTTGGAGATTGCGGC TAAGGCCGGGGATGAGCTTAGGAAGGAGGGCAAGGCGGT GAGGGTCGTGTCGTTTGTGTCGTGGGAGTTGTTTGAGGA GCAGTCGGATGAGTACAAGGAAAGTGTTTTGCCGGCGGA TGTGACTGCTAGGGTTAGCATTGAGGCTGGTTCGACATT TGGGTGGCACAAGATTGTGGGAAGCAAAGGGAAGGCGAT TGGGATTGACCACTTTGGAGCAAGTGCGCCGGCTGGGAA AATATACAAGGAGTTCGGTATTACGGCTGAGGCGGTTGT TGCTGCTGCCAAAGAAATTTCTTAGACTGAAGAGCGAGA GTTTGGCGAAATGGGTACCCGAAGAGCGAGAGTTTTACC ACGACTTGGTCTCTGTTAAAATAATAAGGTAAAAATATC AAGGTTAGGTTTTTCTTGTGATGAAATGGGCAAGGCAGT CCAGAAAAAGAGGAGGGTTTGATTATGAACATTGTGGGC TTTGTAACTGCTCTTGACTTAAGTTGAGTTTTTGTGTTT TTACTTGTAGCTAGTGAGGTTGACAGTTATTTCATACTG CGTTTTAATTTATTGAGAAGCAATTGAGTCTCTTTTCTT TTGTCTATTTGACATAAGTTATTTCTACTTCTAATATCT GCTAACCACCTTGTTAGTAGCAGTAGGGTTGAGCATTTT GTTATGCCGAGCCTATTAGGCTGCACTGAATTATCGAAT ATTGATTGGAGCATTCGGTTATGAAAGTTCAGTATTATG TGAAACTATTCAGTTCGGTACAACCGATCGCTCTACTCT AAGTAGCAGACTGGTTTTCGGATATACTCGATAAAATTG ATAATCTGATCTAAGCCTTTAAAGTTACTTCCGATTTTC AATTTTTGAGAGCCGAATTGAAGTTTGCCGAATTTAATT GGATTGAACTTAACTGAAGTATGCTAAATTAAACTACAT AGAAGTGACTTGAACTTAGTTGAACTTACATTATTGAAT TGAAAT GAAGGAAT GGAATGATCTGAATT GTAGTTAAAG AGAAGTAAAATGTTGCATCAATTGGACCCACCGCATATA GTAGGAAAAGGGTGAGCAAGTGGATGGAGATATGGTGAA ATGTTAGCCTAAATGGGGATTTTTGGGGTGGGTGAGGTT GTTGATCAATCAAGCCCCACCTATCCATGCATGTCCTCT CGCTGGTTTTGAAGCTATAAATCATAATTGGCCTTCATT TGATGATGCAAGGAATAACGAATTTTGGCATATTCTTAC 144 WO 2013/039990 PCT/US2012/054789 AC CTAACTC CAC CATATT CAAAGTAGC TAATAAATTT CA TGAAAAATAAATCCATGAAA-AAGTGTGGT CAGAGACAAC TTTTTAGGAATTCAATTCATTTTATATGTAA-ATTTTTAA ATTTTTTATATAA-AATAATTTCAA-AAGAAATTAATCGAA TTCTTTTGAAAAAGAATGATTTCAAGCACATGAGAATTA TT TTAT CCACAATATT GTAT CAGTAAATT TTCT CT TAAA TTGATAAAAAAAATAGTGTTAACTGCCATTCGGTTATAC TTACAATTGTCTCTTTCAATTACTACTATGCACGTAATT TAAAAACAAAAGTAGAACTTTATTTCTATGCCTTATTGC CAAAATACTCAGGCCATAGGCTAGTCATTTTGCAGAAAC GT TTGCAC CAGTGCACAAACAATCGGGCAAA-AT GTAT GG CCAGTTAGTTGCCTCAGCATTTTGGCAA-ATCGGCAAGTT GTATTTACATTTTTCAATAGAAACGTATAAAA-AATTTTG GAATTCGAAAAGATGTCCATTGGTTTCCTTAGATGCATT TTTAAAGCTAATCTAGTTATTTCGAAGGTATATACTTCT TCTTCTATATTTACAATTTCATATTATATAGTTTCTGTA ATTATAGTGATATTAGAAGAAGGGCTAA-AAGGCTTTACC AACACAACCTTTTTGGTTTGGTCTTCATTCAA-AAGCCCA TT CCACAATC TT CATTT TAT GTCCC CACAAA-AC CTAC TT CT CTCT CAC CAA-AC CTAC CTAT TATAAT GAC CAAA-ATAC TGATTT GGCAATAC CTAATTGGTAAGTTGCAAATCATAA CAATAAAATCGACTTCACACTATCAAA-ACCTTCGTTAAC TACCACGTCCCACAGTGTTTGGTATAGACGCCACATTCT CAGTCTCACCAACCCCCTTTCTTTTCAGTCCTTCAA-ATT CACAACATTCCAATTTAGCCCACAAAATTTTATTTTCTG T GC C TCCAAT TC TAT TATACACAAT CCCC TAAC TTAACT TTTTATCACTAAAAATCAAATAA-AGTTGATGGGTCAATT TCGAAAATTGATGAAATATGAGGTTGGTAGGAAGATTGA AATACCCTCAATTGATTTGAATACAACCAACTCCTAATT ACAACTAA-ACCCTCACCAATCTCAAATCAACGCACCCAT TTCTCTTCTTCCCCATTGAGAATTCAAGACCTCCATAGG GATCAGAGAGTTGCAGAGAACTTGATAGCCCTACTTGAA TGGCTCAAGT TAGCAA-AT TCT GCAATGGAGTTCAAA-AGA CC TACACTTT CCC CAATT TTT CTAAACC GGAAACCCC CA AATCTATGCCTTCATTTTCAATCAGGTCAAGGCTTAATG GGTCGCCGGTTTCATTGGCTGTAA-ATCGGAGAAGGGGCG GCTGTATTGTTGCTAAAGGTAAAGGTAGTTCTTTTCAAG TTTCGGCTTCAGTAGCCACAACAGAGAA-ACCCTCGACTG CGCCGGAAATAGTTTTGCAGCCAATCAA-AGAA-ATCTCCG GCACCGTCACTTTGCCTGGTTCAA-AATCGCTGTCCAATC GGATTCTTCTACTTGCTGCTTTATCTGAGGTATGAATTG CT CTGGTTTT TCC GGCAACAGCAT TAT GT GCCT TT GAAT T GTAAGC TGAGGAGAT T TCAT TGTT GT CAT CAT TATAAT TGGTGCTTCCTTCTTGTTTGTTAGAAACTTAGTTGAAAG GCAA-AC GAAATTAGGATCACATAGATTAC TAAC TGTCAA TAGTCTATTTAAATTGTTGTTATCGATCGTTCAGGGCAC AACTGTTGTTGACAACTTGCTGAATAGTGACGATGTTCA TTATAT GCTGGGCGCACT TAAAACACTGGGACTACGAGT GGAAGACAACAGTGAA-AT TAAACAAGCTATTGT GGAAGG TTGTGGAGGTCAGTTCCCTGTGGGTAA-AGAATCAA-AGAA GGACATTCAACTTTTTCTCGGAA-ATGCCGGGACAGCAAT GCGCCCTTTGACTGCTGCAGTTACTGCAGCCGGTGGAAA TTCAAGGTCTTTTACCTTCCCCCTTTTTACCCTTGCAGA _________________ATTATTGGACTTGTATTTTTGAGACTCTATATGGTTTTA 145 WO 2013/039990 PCT/US2012/054789 ATCAGAGTATGTGGTTTAGGATTTATAAGCTTGTCTTAT ACGCACTCAGTATGACCTAATCAGGTTTAACAGCTAGAT GGAATCAAATTGTTTCCTCTATTTTGTAATTCATATGGT TTGCATTTTCGTCTGAAATGGGATTTGGGTACAAAGCCT GAATGAGAAATTTTGATCGTTAATTTGAATGAAGTGGCT GCTTTATCTGGGCATTAGATGCTGAAATTGTAATAGGGT GTATTTTCCTGGACATCTTTTTTCAAAGGATTTGGATTC TCTAAAGTTCAAACTCAATGAATGGTTGAGATTGAGTGA AATGTACAACTTTAGAG 73 Euphorbia Genom 4647 CTTTAGAGAATCCAAATCCTTTTCAAATTATTTCCTAGA heterophyll ic TCTATTGTCGATTTCTCATTTATATTTTCAGTTTTAGGC a AATAACTGAATGATATGCAGTTATGGATGGCTTTGGACT CTGGTAATGTTTTGTTAATGTACACTACTGCCTCCCAAG GGCTGAGCATAATGCGGTTTAAACCGAAACACCGATCCA AACCGAATTATGATATTCGGTTCAGTTATTTAATATTCC TGTTTTTTATTCGGTTTTCTGTTCGGTCTGGTTTAAGAG GCAAAAATTGTGAAAAACTGAACCAAATTATAGGTTTTC ATATGCAAGTAGGCCCAAGCCGAACCCAAACCAATAGTT TCATTTTCATCTATAAGTCATTATCTAATTCAACCAAAT GATTCTTTTCTTTTATTTTCTCCAAGTAAACCCCAATTA ATTGCAATTTTTGATAAATTCTGTTCAGAAAAACCGAAA TTTAGTCTAAATGTTTTCACTTTCAGCTCTGAAAATTCA GTTTTTAGGTGTAATTCGTTTCGGTTCGGTAAGCATTTT TAGATAACTCAGCTGGGCTTATTCAGTTTAGTATAGCCA AATGTTAAACCCCTGGCCCCTATCGAGCTCTTTCCTCTA AATTTTTCTAATTGGAATTAACTATCAAATGTGTTTCAG CTACATACTTGATGGGGTGCCACGAATGAGAGAGAGACC AATTGGGGATTTGGTAACCGGTCTTAAGCAGCTTGGAGC CGACGTCAATTGCTCGTCCACAAACTGCCCCCCTGTTCA TGTAAATGCAAATGGCGGCCTTCCTGGGGGAAAGGTATA ATATATCGTCTCATTAAGTAAATATGAAAGAACAAGTTT TCCTCTTGTTTTGACTAGATCCATCATTATTGTATCCCT TTTAGGTTAAGCTCTCAGGATCAATTAGTAGCCAATACT TGACTGCTTTGCTCATGGCAGCTCCCCTGGCTCTTGGAG ACGTAGAAATCGAGATTATCGATAAACTAATTTCCATTC CTTACGTTGAGATGACTTTGAAGTTAATGGAACGTTACG GTGTTTCTGTAAAACACACTAGTAGCTGGGATCGTTTCT TCATTCAAAGAGGTCAAAAGTACAAGTAGGTATTTTCGT TGATTTACGAATTCCGAAACCCTCGATTTTCGTTCGAAC AAAAAAATGAAAACCCGGAATGTCAATTAGGTCCCCGGG AAATTCATATGTTGAAGGCGATGCCTCGAGTGCCAGTTA TTTCCTGGCCGGTGCAGCAATCACTGGTGGAACTATCAC TGTAGAAGGTTGTGGCACAACTAGTTTACAGGTATTTTT TGTAGTTATTGCTTTGTGTTGGTTAAAATTTCAGAATTT TTTTCGTATTAGGGATACAAAGTGACTTGTTATATGGAA TTTCAGGGAGATGTGAAGTTTGCCGAGGTTTTAGAGAAG ATGGGAGCAAAAGTTAGCTGGACAGAGAATAGTGTTACA GTGACTGGGCCACCGCGAAATTCTCCTCGTGACAAGCAC TTGCGTGCCATCGATGTGAACATGAACAAAATGCCAGAT GTCGCTATGACATTGGCTGTCGTTGCGCTTTTTGCTGAT GGCCCTACTGCCATAAGAGACGGTAACTTCATTTAATCT TTTCGCAAAAATAAGGCTTAATGCATCTAGACCCCCTAT AGTTGTCCCTAAAAACCTCTTAGCCCCCTGAACTTGTAA AAGTGGACCTTATGGCCCCCTGAACTTGTAAAGGTGGNC 146 WO 2013/039990 PCT/US2012/054789 CTTATAGCCCCTTGAACTTGGGAAAAGCGAACCTCAAAG CCCCTTCATGATAACCAGGGCCGTTCCTGGGGCGGGGCA ATAGGGGCGACGGCCGGGGGCCCAATGGAATAAGGGGCC CATTTTTAAGGATTATTAAGTTATTTTTATTAAATTAGA GTTTAAGTTAATTAAATAGTTCTTTTGTGTAAAATATTA AGAATAAAATACTATTAAATCTAAAGTGATTAGTTAGTT AAAGACACGTGTTAGCTTTGTTTGAATTAAACTCTAATC TCATTGATTTTTCTTACCTCCATTATCACCACCATCATC ATCTCTTAACATTTATTTCCTTACAAATTTTCTTTAGTC TATTCAACTTCTAAATTTAAAATTGAAGTTGAAGTGCAT TCATCTTCCATACTATACTGCTATCAATCTCCAAATTTC ATTCTTGTTCAATCCTTTTAGTACCTATAAATAATTCTT CATTTACTCTTTCAACAACATGTATCTAAAAAAAAAGTT AGAGCATGTTGATGTAAACTTTATTAGCGATTTTGCGGT TAGGTTTACTCATAGACATCATTTTATTTGATCTATGAT AAAGTTTTAGTTATAGTATTATTTTCTGCTTTATAATGT GAAATTTTGATGTTCTGTTTAATCTATTATTAAATGTCG TAGTAAAAGTTCAATATTATATGTTTCATTTTAAATTTT AACTCATTAATAGGGCCCCGATTTTTATTATCGCCCATA GGCCCCAAAAAGGTAGGAACGGGCCTGATGATAACATGC CCAATTTTGTTCCGGTTAATTAATCTTCGATTCAATCTT TATCAAAACAATCTTGGAGTCAATTTCTAGAAAAATAAT ATTTGAAATATCAACATCAAGGGCCTGTGGGGTTCACTT TTAACAAGTTCAGGGAGCTATAATGTCAAGTTTAACAAG TTTAGGGGGTTCAGGGACCTTTGTAAGTTCAGGGGATTA AGGGGTTTTTAGGGACAACTATAGGGGGTTTAGATGTAT TAGGCCCAAAAATAATTATAAATTTGAAAGCGTAGTTTA AATTGCCAAACCGAGTAAACTGTTTCGGCATTCTCTTGT TTCCAGTGGCAAGTTGGAGAGTGAAAGAAACCGAAAGGA TGATTGCTGTTTGCACAGAACTCAGGAAGGTTAGTTGCT GATAAATTTTGGCTATTATAAAAACAAAACTTATTGGCA TATAATTATAATTTATAATGTTGGATTAAATTGATTAAT TATTCCATTATATATTCAGTTAGGAGCAACAGTAGAGGA AGGAGCAGATTACTGTGTGATAACTCCGCCGGAAAAACT AAATATAACGGAGATTGACACTTACGATGATCACCGAAT GGCGATGGCCTTCTCTCTTGCTGCCTGTGGGGATGTTCC GGTCACTATTAAAGATCCCGGTTGTACTCGAAAAACTTT CCCTGACTACTTTCAAGTCCTCCAAAGCTTTACCAAGCA ATGACCACGAACCCCTAAAACATTGGAGTACTAGAAATG GATCAGGCTCTTATATTCAATGGATCATTCAAGTGAGTT TATGTTATTAATGTGCCGGACATAACAGATTTTGTTAGA CAATGTATACCGGATGAATTTGTATTTTATGTTTTGTAT TTGTATTCTATCAAGTTGATCAGCAATAAATGGGTGAAT GTGTTAATTTTTGTGATATACTTACAGTGTTATTATTCA GTTCGACCGGTTTTACTGTGAACCGGCTATGGTCACAGA GCGATTTAGTTAAAATTGGGTTGAACATGAAAAAATCGG TAAACCCTTGTGGCAAAAATAAAATGCGTTGCTAAACAC ATAAAAAAGATTTGTAATAGCCTTATACGTTCTTTTCCA AAATTCCTTTGGCAACTTTGTGGAACGTCGTAATAGACC TAGAAAGCGGTGAAATAGTCACTTGAAATCATAAACTCT CTCTCTATATATACCTTTTAGCCCTTCAATTTCTTTACT AATTGAAGCAAGTAAAATACAAACTCATTTCTTTTTCAA GTTAGTGATATAAGTTTGTTTCTTTAACACCCAAAGATA ACACATCCCCAAGAAGGAATACTCATTCACTTGTTGAAG 147 WO 2013/039990 PCT/US2012/054789 AATTATCTTCTTTATTAGTTGAAACATAACTTACATCTG AATAATCTTCGAAAACCAAAGAAAATTCCGTATAGGTCA AACCATGATCCTTGGTTCCTTTGAAGTACTTTAATACTC GGCCTAAAGCTTGTCAACGATGCGAACTATGACTACTAG TATATCAACCGAGCTTTCCAACAACACAAGCTATATATG GCTTAGTGCTAATCACATACACACTTTTTATATACACAC TTGCATACTTGGTTGATAACAAAACCATTAGATAAAATC ACATCATCGAACTTTTAATGTCACACTTTTCTGTGGGCG TTTTAGCCCATATAACAAATTCTTTAGCTTGCATACCTT ATTTTCTCAACCTGACATAACAAACCCTTGAATCTGATT GTTTTTCGATGCCCGAGACCAAAGAATATCATTATAATA CCATCTATATAAAAAAATGAGACTGAATCACCTATATTT CGGATATCAACAGGTTTCCACAACTTCTTCAACACTTAT TACACAAACTGCCTTAAAATTTACAATTTGATGGGTATA GTAGATGATTGCAGAAAGGCTTTTTTTAAGCTCAAAAAT CACGTGGATGACATGGAAAGGAAAAGAGGAAGAAGCTGT AAAGATAACATCACATTCCTCAAAAACCAATCTCAATCT AACATTAAATCATTAGGCATGGAACATGTTAGCTTTGTC TTTATAATTAAAATATTATTTATCTCCATTTTATTTTTA TTTTTTAATTTTATACACTTTTTCACATGGGCTAGTTTG TTGGAT 74 Euphorbia Genom 378 TTATATTAGCTAAAATTTGGTAGTCTTTGAAATTTAAAC heterophyll ic TCAAAAGCTTGACATGTTTTTTGTAGGTCCTCTTGGACA a GGGAATTGCCAATGCTGTTGGTTTAGCCCTTGCAGAGAA GCACTTGGCAGCTCGATTCAACAAACCAGACAACGAAAT TGTTGACCACTACACGTATGATAACCTCCTCTATAATTA TGTTACTTTGTGTTGTTTTGTTTAATGCTAGATTAATGT GACATGCTGTAATTTAATATTGTTCTGTGTTTATCTTTT TGTTAGATATTGTATATTGGGAGATGGTTGTCAAATGGA AGGAATTGCAAATGAAGCTTGTTCCCTTGCTGGACATTG GGGGCTTGGAAAGCTTATTGCTTTCTA 75 Euphorbia Genom 220 GTGTGAATTAGTTAAAAAGACCATTATTTCTAGACGAAG heterophyll ic GGAATATTAAGTAAGAAAAAGGGAAAAGCAAAAAAATAT a AAGGACCAATCAAAGACCTAGAAAAAGCTAAAAATAGTG CCAATACATTGTAGTATAGATACAAATAAAAATAATTCA CATTACTCATTTATATTACCTTAAAGTATGATTAGTGTC ACAATTTTACTGTTCTATCTTCTGT 76 Euphorbia Genom 4459 GTCTAATGAACTTTGATACTATAATCAATTGGTGAATAT heterophyll ic TGTGATTTTATTTTTTATAAGATAATAGGTACTTTATTT a TTCATTATTGTTGGATTAGTGATGTGGAATTCAAACAAT GGTAGAGTAGCATATAATTTTTAATTATATTTATTACAT TTATATTATATAATCTCACAAAATATAATTATAAAAGGT GATATGCTTATATATCTATAATAACCACTATTAATCTTG GTTGTTAGCAATAAGAGTTAGTCTAAGTGGTGAGTGGTT TGGTATCGCTTAAGCAAGGTCTTGTGTTTAATTCTGGAG TACGCAAAAAATTTTATCGAGAGACTCACCTACCATAGT TAGGTGCGCGACCCGTATCGAATCTGGATGTAGTCGAAA CAAAGTTTCGGTAAATCAGATGAACAATCGAAGAAAGAA CCTCAGCGTTTGTTGAATAAGAAATTAGAAGGCTTACCA AACACAGTATTTTGGTTAGTATTCAAAAGCCCATTTTCA ATGTCCACCGGGTCCCCACTAAACCTACCCACTTTCTAT CTCTCACCAAACCTGCCCTTAATGGACCAAAATGCTGAT TTGGCAAAATCTAATTGGTAAGTTGCTAATCACATAATA ACAAAATTGACTCTATATCTTCAAAACCTTGGCTATCTA 148 WO 2013/039990 PCT/US2012/054789 C CAC GT CCCAC TAC CATAC GC CACT TCT CAATC TTAC CA ACCCCTTTTTCTTTTTGGCCCCATAATATTCTTAACATT TCAATTTAGCGATTTGAGCAAGTCAAATCATTTTTTTAA TTTCATTTGTCAAACTCCATTTTGAAGAATTTACAGTTC TT TCAT TC TAAC TAT CAT TCT CATT TTT CATAT TAAATT AT CAAAAAATAATAATAT TT TAT TAT TATAT TAATT TAT GTAGAT CGTT TAT GT TAT GTT GTAC TGAAC TAATAA-AAT AAT TAAAAACAT CAAAAT TCAAACAAAGTAATAAAATAA TGATTCCCTGAA-ATAGAGAATGCCCATATACGAGAA-ACC CT CGTT TT GAAGAATACC CTAT GGAGAAT GGTT GGAC TT AGGTCATTTTTATTTAGATTACTACTCAATGTAGTTCAA TT CAGTAATCAATAAGAATTGGTCCAAGT GGTAAGCGAC TTAGTATCGCTCAGGCAAGGTCTCGAGTTCGAATCCTGG TGTATGCAATTCGGATCTGGATGTAGTTGGAGCAA-AGCT CCGGTGAACCAGATGAATAACAAAAAAAATGTAAACTTT TAGTTAATATTTGTTATTGTAATTGAAA-ATCAAATAAAG TTGTGGGTCAAATTTGGAAA-ATTGTGAA-AGATTGGAATA ATGAAACACCTCAATTGTCGTTACAATAACGCCTAA-AAC CTCACCAATCTCAAATCCAGAGCAGCCATTTTTCTTCTT CCCCGTTGAGACCAGCAAGAATCAGAGATACACGGAGAT TGGTGGAGGGGGAT CCTGTAGCTCTAGTTAA-AT GGCACA AGTTAGCAAATTCTGCAATGGAGTTCAA-AAAACCTCCAT TT TCCC CAAT TTTC CTAAACC CGAAACCC CCAAATCC GT TCCTTCGTTTTCAATCAGGTCAAGTTTTAACGGGTCGCC GGTTT CAT CGGGT CTAAATC GGC GC CGAACAA-AGGGC GA TTGTATTGTTGTTAAAGGTAAAGCTAGTTCGTTTAA-AGT TTCAGCTTCAGTAGCCACAACAGAGAAACCCTCTACTTC ACCGGAGATCGTGTTGCAACCAATTAA-AGAA-ATCTCCGG CACTGTCACTTTGCCGGGTTCTAAGTCGCTGTCCAATCG GATTCTTCTCCTCGCTGCTTTATCTGAGGTATGAATTGT TCTGGATTTTTCGGCGATTGCATTCTGTGCCGTTGAATT GTAAGC TGCGGTTT TAGTATAAT CATAAT TAGATGAAGC AGAAAGGAACTTAGTTCTTTTGCATTTTATGTTCAGAAT CACATAGATCACTAATTGTTGGGGAAATC TGGAAATGAA GGCTAGATAAATAT GAAGTTATAGC GAACATTGTGAT TG AAACTTATTGACAAGAACTTAGAACGAATGTTGTTGTGA TGTTATGAA-ACAAAAAAGTCTGTAAAACGTTATATTTGC CAATGCGTTCTCTCTATATATATATATAGAGAACCGAAA TAACCGTCATATGTTAACTGTTTTTGTAGTTATTTTCGT C TAAGT CGC GACAT GGTC CAAATCC CAAATT CAT GAATT TT CCAAGGGAACTT TTAC TT TAGCT CGAC CC CAGTTT GG GGCAC TAC C CCC GAAATC CGAACAT TGAACTT GAACAAA GCATGCACTCCACACTCTCGTGACTTGTTCAATGAA-ATA TCACAATCGCACAACTAGTTGATCTAATTACAC TAA-AAT AC TAC TAACAACAC TTAAT CAACAGTC TAT CAT GTT GTT GGTTTTTCTTTGAACTTCTGAAGCAGGATAGATAA-AGAT C GT TC CTTCC CAC TAATT GATAC TAT CAT TGCATT GACC TTTAAATTATCTTCTTTTGGTGCATATAGATTACAGATT TAGTTAAATCACGTAAAGTTTGGGCTGAATTTTTGTTAA AATAAACTTCAAATTTGAAATCTTTACTAATTTTTCAGT CC CTAGGTTT CCATATCC CCT TTAT TTC TAAAAGCC GTT GTTTTGTTGGCATGCCTTATAATTGATTTTTGTTTATTT CTTGCAATAAACAACTTAAA-AACTCTGGCCTTGGAAGCC _________________TTTTTATCTGTGTAAAGTAGTGATTCTGAGTGTTCTACG 149 WO 2013/039990 PCT/US2012/054789 TTCAAAATTTTGCTTCTCGAGACCATAAAACGGTGCTTT ACATCTATTGTCCAGGGCACAACTGTTGTGGACAACTTA CTAAACAGCGATGATGTTCATTACATGCTTGGCGCACTT AAAACATTAGGACTACGAGTAGAAGACAATAGTGAACTC AAACAAGCTATTGTGGAAGGTTGTGGCGGTCAATTCCCA GTGGGTAAAGAGTCAAAGAAAGACATTCAACTTTTTCTC GGAAATGCAGGAACTGCAATGCGTCCTTTGACTGCTGCA GTTACTGCAGCCGGTGGAAATTCTAGGTTTACTTTTCCC CCTTTTTTTACCCTCTTTAGACATGCCTTGCTTTATAGA ACAATAAGCACTTATTTTCCACGACTTATGAGATTCTAT ATGGTTTAACATGTATCTAATGTGTTTCAGCTACATACT TGATGGGGTGCCACGAATGAGAGAGAGACCAATTGGGGA TTTGGTAACCGGTCTTAAGCAGCTTGGAGCCGACGTCAA TTGCTCGTCCACAAACTGCCCCCCTGTTCATGTAAACGC AAATGGCGGCCTTCCTGGGGGAAAGGTATAAATATATCA TCTCATTAAGTAAATACGAAAGAACAAGTTTTCCTCTTG TTTTGACTAGATCCATCATTATTGTATCCCTTTTAGGTT AAGCTCTCAGGATCAATTAGTAGCCAATACTTGACTGCT TTGCTCATGGCAGCTCCTTTGGCTCTGGGAGATGTAGAA ATCGAGATTATCGATAAACTGATTTCGATTCCTTACGTT GAGATGACTTTAAAGCTAATGGAACGCTACGGTGTTTCT GTACAACACAGTAATAGCTGGGATCGTTTCTTCATCCCA GGAGGTCAAAAGTACAAGTAGGTATTTTTATCGATTTAC GAATTAGGAAACCCTAGATTCTTTCAAACAAAAAACGAA AACCTTAAATGTCAATCAGGTCCCCGGGAAATTCATATG TCGAAGGCGATGCCTCGAGTGCCAGTTATTTCCTGGCAG GTGCAGCAATTACCGGTGGAACTATCACTGTAGAAGGTT GTGGCACTTCCAGTTTACAGGTATTTTTTAAAATTTCAG ATTTTTTTTCGTATTAGGGATACAAAGTAACTTGTGATT GGCTGCTTGTTCTATATGAAAATTAAGGGAGATGTAAAG TTCGCTGAGGTTTTAGAAAAGATGGGAGCAAAAGTTAGC TGGACGGAGAACAGTGTTACAGTGACTGGGCCACCACGA AATTCTCCTCGTGACAAGCACTTGCGTGCCATCGATGTG AACATGAACAAAATGCCAGATGTCGCTATGACATTGGCT GTGGTTGCGCTTTTCGCTGATGGCCCCACTGCCATAAGA GACGGTAACTTCGTTCAATCTTCTCGTGAAAATAATAAT TAATATTCTTCAAATAATCTGAAAGGACATTTTCTTGAT TCCAGTGGCAAGTTGGAGAGTGAAAGAAACCGAAAGGAT GATTGCTGTTTGCACAGAACTAAGAAAGGTTAGTTGCTG ATAAATTTCGGCTATTAACAAAACAAAACCTATCGGCAT ATAATTATAAGAGTTAACTTCAAAAACATAACCTGTGGT TTCACTTATTTTTAAAAGGGGGTCTGTGAAATTTTACAT TACGAAACATGGTCTGTGGTTTCAAAAACTTTGCAAATA AAGGATCCTCAAT 77 Euphorbia Genom 1339 TATTCAGTTAGGAGCAACAGTAGAGGAAGGAGCAGATTA heterophyll ic CTGTGTGATAACTCCGCCGGAAAAACTAAATATAACGGA a GATTGACACTTACGATGATCACCGAATGGCGATGGCCTT CTCTCTTGCTGCCTGTGGGGATGTTCCGGTCACTATTAA AGATCCCGGTTGTACTCGAAAAACTTTCCCCGACTATTT TCAAGTCCTCCAAAGCTTTACTAAGCAATGACCACGAAC CCCTGAAACTTTACTAGAATTGGATCAGGCTCTTATATT CAATGGATCATTCAAGTGAGTTTATGTTATTAATGTGCC GGGCATAACAGATTTTTTATACCGGATGAATTTGTATTT TATGTTTTGTATTTGTATTCTATCAAGTTGATCAGCAAT 150 WO 2013/039990 PCT/US2012/054789 AAATGGATGAATGTGTTAATTTTTGTGATTTACTTAAGG TGTTATTAATCAGTTCGACCGGTTTTAGGTGAACCGGCT ATGGTCTCGGAGTGATTTAGTTAAAAATTGGGTTGAATA GGAAGAATCAAACCCTTATGGCAAAAAGAAAATGTCATG TTAAACACATAGGAATGCGTTGTAATAGCCCTTTATGTT TTATTCAAAATTCCTCTGGTAACATGCAGAATGTTGCAA AGGACCTAGAAAGCAGTTAAATAGCCACTTGAAACCATA AATTCTCTCTCTATATATATTCTTTTAAGATAAAAAATC GGTAAAATTAGCAATCATGTCAATAATATTGATTATACT ACATATCATTAACTTCACGTTTCACGAGTATGAAGTTTG GTTTGATATTGATAACAATGTGTACTTATTGAAAGGGAA TTATAAAAATGACTTGGATAATATCTAAAGTTGTAATAA TACTTTCAAATAGAAACGAAGTTGATGGTTTTCCCAAAA TTTTTAGTTGAATAAAATCAAAGTAAAATCATGAACTTA GAATAAATTTTCATTGTGTAAAAAAATGAACCAATAACA ATCGTTGCTGAAAATATCCTATAAGTGTTGCCAATGCCA GATTTTTATAAACCTGGAATGAGCATTTGCAATGCTTTG AAGACAAAGAGTTGCTAAAAGGCGTGTCCATTAGATCAA TTGCATCTGTTTATAACAAAAACATTGCAAAATGGCATG TCCATTCGAGCAGTTGCAATAATTCATAACAAAAGTGTT GCGAAATGTAGCTTCCGGCTCTCATAAGCTAAGTGTCGT AATAGAATTCGAACAAGCATGCACTTCCTGCTCTCCTGA CTTGTTCGACGAAATATTACAACCGCATTGATCAACTAG TTGATCTAATTACACTTACCTACAATCCTCCACATTTTA GTGTAATCCATGA 78 Euphorbia cDNA 1668 CGTTTTCAATTAGGTCAAGTTTTAACGGGTCGCCGGTTT heterophyll CATCGGGTCTAAATCGGCGCCGAACAAAGGGCGATTGTA a TTGTTGTTAAAGGTAAAGCTAGTTCGTTTAAAGTTTCAG CTTCAGTAGCCACAACAGAGAAACCCTCTACTTCACCGG AGATAGTGTTGCAACCAATTAAAGAAATCTCCGGCACCG TCACTTTGCCGGGTTCCAAGTCGCTGTCCAATCGGATTC TTCTCCTTGCTGCTTTATCCGAGGGCACAACTGTTGTTG ACAACTTGCTGAATAGTGACGATGTTCATTACATGCTTG GTGCTCTTAAAACACTGGGATTACGAGTGGAAGACAATA GTGCGATCAAACAAGCTATTGTGGAAGGTTGTGGGGGTC AGTTCCCTGCGGGTAAAGAACCGAAAAAGGACATTGAAC TTTTTCTCGGAAACGCCGGGACAGCAATGCGCCCTTTGA CTGCTGCAGTTACTGCAGCCGGTGGAAATTCGAGCTACA TACTTGATGGGGTGCCACGTATGAGAGAGAGACCAATCG GGGATTTGGTAACCGGTCTTAAGCAACTTGGAGCTGACG TAAATTGCTCGTCCACAAACTGCCCCCCTGTTCATGTAA ATGCCAATGGTGGTCTTCCTGGGGGAAAGGTTAAGCTAT CAGGATCAATTAGTAGCCAATACTTGACCGCCTTGCTCA TGGCAGCTCCCCTGGCTCTTGGAGACGTAGAAATCGAGA TTATCGATAAACTGATTTCCATTCCTTATGTTGAGATGA CTCTGAAGTTAATGGAACGCTACGGTGTTTCTGTAAAAC ACACTAGCAGCTGGGATCGTTTCTTCATTCAAAGAGGTC AAAAGTACAAGTCCCCGGGAAATTCATATGTCGAAGGCG ATGCCTCGAGTGCCAGTTATTTCCTGGCCGGTGCAGCAA TCACTGGTGGAACTATCACTGTAGAAGGTTGTGGCACTT CCAGTTTACAGGGAGATGTAAAGTTCGCTGAGGTTTTAG AAAAGATGGGAGCAAAAGTTAGCTGGACGGAGAACAGTG TTACAGTGACTGGGCCACCACGAAATTCTCCTCGTGATA AGCACTTGCGTGCTATCGATGTGAACATGAACAAAATGC 151 WO 2013/039990 PCT/US2012/054789 CAGATGTCGCTATGACATTGGCTGTGGTTGCGCTTTTCG CTGATGGCCCCACTGCCATAAGAGACGTGGCAAGTTGGA GAGTGAAAGAAACCGAAAGGATGATTGCTGTTTGCACAG AACTAAGAAAGTTAGGAGCAACAGTAGAGGAAGGAGCAG ATTACTGTGTGATAACTCCGCCCGAAAAACTAAATATAA CGGAGATTGACACTTACGATGATCACCGAATGGCGATGG CCTTCTCTCTTGCTGCCTGTGGGGATGTTCCGGTCACTA TTAAAGATCCCGGTTGTACTCGAAAAACTTTCCCTGACT ATTTCAAGTCCTCCAAAGCTTTACTAAGCAATGACCACG AACCCCTGAAACTTTACTAGAATTGGATCAGGCTCTTAT ATTCAATGGATCATTCAAGTGAGTTTATGTTATTAATGT GCCGGGCATAACAGATTTTTTATACCGGATGAATTTGTA TTTTATGTTTTGTATTTGTATTCTATCAAGTTGATCAGC AATAAATGGATGAATGTGTTAATTTTTGTG 79 Euphorbia cDNA 783 ATGTTGAAGGAGATGCCTCGAGTGCCAGCTACTTTCTAG heterophyll CCGGAGCAGCAATTACCGGTGGAACTATCACTGTTGAAG a GTTGTGGGACTAGCAGTTTGCAGGGAGATGTGAAATTCG CCGAGGTTTTGGAGAAGATGGGAGCTAGAGTTACCTGGA CGGAGAACAGTGTAACTGTGACTGGACCACCACGCGATT CTCCTCGTCAAAAACACTTGCGTGCTATCGATGTGAATA TGAACAAAATGCCAGATGTTGCTATGACATTAGCTGTGG TTGCACTTTTCGCTGATGGTCCCACTGCCATCAGAGATG TGGCAAGTTGGAGAGTGAAAGAAACCGAAAGGATGATTG CTGTTTGCACAGAACTTAGGAAGTTAGGAGCAAAAGTTG AAGAAGGGGAAGATTACTGTGTGATAACTCCACCCGAGA AACTAAATATAACGGAGATTGACACTTACGATGATCACC GAATGGCGATGGCCTTCTCTCTTGCTGCCTGTGGGGATG TTCCGGTCACTATTAAAGATCCCGGTTGTACTCGAAAAA CTTTCCCTGACTATTTCAAGTCCTCCAAAGCTTTACTAA GCAATGACCACGAACCCCTGAAACTTTACTAGAATTGGA TCAGGCTCTTATATTCAATGGATCATTCAAGTGAGTTTA TGTTATTAATGTGCCGGGCATAACAGATTTTTTATACCG GATGAATTTGTATTTTATGTTTTGTATTTGTATTCTATC AAGTTGATCAGCAATAAATGGATGAATGTGTTAATTTTT GTG 80 Euphorbia Genom 2185 GACAGACTTTGACCCAGGCAATTGAACAGTACCAGAGAT heterophyll ic CTCTTTGATGGGTTGTAACACAATTTCTGGGACAGATGA a AGGTTTCTCAGCTGCAGCAGCAACAGAAGCTTGAATCTT GGGAACAATTGATGATTGCCCACCAACTCTTTTATTGGT TAAAGACATGAACTTTGGAGAAATTCTCAAGTTTGATCC AAAATTAAGAGTTTTTGAAGATTTGGGTAACTGGGTTTT GGGTAAAGTATGGTGCAATTGACCAGTATGGACACCATT GTTGATGGTAGTAGCTTGAGCCATTATTCTTCCTCTGAA TTTGGCGTTGTTTGTTGGCTGAAAAAGTTAGGTGGATTT TAGGCTTTTAAGAGAGAGAAGGGAAAGAAGAGGGCTTAG TTCTTACCAAACCAAAGTTTTGGTGGGCAAAGAGAAAGT GGGTTGGTGTAGACTCTAGTAGAGTAGAGGGAATCATTA TAAGAGTTTGTTGTTGAATTTTTTAAAAGTTTTTTGCAT TCCTCCGATTTGCAACACGGTTTACCTACTGTTTATTTG AATTTTTTGTGTTGAGAAAAGGCTTACAGGCTTGCTCTT GTATATGTGTATGTATTTGCTTTGTGGTTAAATATGCTG CATGTTGTAATGAAAACTCTGCCCGGGGATGGTGGGCTT ACACGCCAAAGAAAAAGATTGTTTTCCACAAGCAAAAAT ATCCCATTGGCAACAGCGTGCAATTATTTAGGGAATGGT 152 WO 2013/039990 PCT/US2012/054789 GTTAGAGCATTAAAATTGGAAAATAAATGAGCTCTCATT TTGTTCAAACCATGAGAATTTTCCCCTGGTCCAATATTC AGGCGTTTTGTTTCATTTGTAAAAATTACGATCATATTT CTCTTTAGTGAAGCAACTGATTGGAAAACTTTGGTATAT GCCATATCTTTCCAAGTTAAAGAGTTCCCAGGCATCATC CTCAATGATCTTCCTCTATATTCCTGTACAAATATTGTT GATAGGAAGTTCATTCATGCCAATAACAATATGTCTCTT GCGAATTTCTAGAAGACCAGAAATTTGTTGTGACCTGTG GAGTTCTTCCAAAAGTATCCTCTGTGCGACGCATGAAAA AAGCCTTTGGGCTAGACTACTGAGATGCAGCTGCCTGGT AATTCATGCCTCTCTCCCAAGAGAGTACGAGAAGTCATT TATAGCCGCTTAAGAGAGCCAAGGATCAATTTAGGCGTG TTCTATTTCCATATCTTAATGTATCACTGAAGTTTAGCA AGTAAACAAACATCACAATCCCTGATGCTTGCATAGTCA TGGCAAATGTTATACTCTTTGTTTACATATGAAAAACCA GATATTACTCCATATTTTTAGAAACCAGCAACCAAAGGA GCTTAAATGGTCCCTGCTCCTAAGTCATATCTCTTGGCA ATGGGGTGTTTGTAGATCTTGAGTGCTGCCAGTCCACTT ACTGTAATGCAATACATCAATATTGAGCTAGTTTCTCAT GGGAAAAAACCATAGAAATGGGACAAATTTGATGTTAAT GTTCTGTAATCCAACTTGAGGATTAGTTTTATCACATAA AAGCTACATTGAAAGTTCTATTATTATTTTGAGTTTGCA TCTTATGTTGTTTTTCCTTTGTGATTTTATCCATTTTCT TAACTAGTTATTCGTTTCCTGAAGTTTTTAGTGTCATAA CTCCTAATCACAATCATGCTACAGGGCACAACAGTGGTC GACAACTTGCTGTATAGTGATGATATTCTTTATATGTTG GACGCTCTCAGAACTCTTGGTTTAAAAGTGGAGGATGAT AGTACAGCCTAAAGGGCAGTCGTAGAGGGTTGTGGTGGT CTGTTTCCTGTTGGTAAAGATGGAAAGGAAGAGATTCAA CTTTCCTTGGTAATGCAGGAACAGCGATGCGCCCATTGA CAGCTGCGGTTGCCGTTGCTGGAGGAAATTCAAGGTTTG TCCAATTATATTCTTTATGTGAGTGTTGTTTTTTGTGTT AGTTTCAATCATGAAGGTACTAATGCAGAAGCCGTACCC CTGAAATTTTCTTATTTTGTATATATCAATTGGTAATTG ATGTAAGATATTTTTCCGAGAGGAATAAAAACAGGGGGA TAGAGAATATTAAAGTATTGTTCTATCACATTAACTTTT TATCAAAGGTGTACATTGTGTTTGTGAAGTTTATAGAGC T 81 Euphorbia Genom 1702 ATTTTCCTGAACATCTTTTTTCCAAATTATTTCCTAGAT heterophyll ic CACTGTGAATATCTCATTCATATTTTCAGTTTTATGTAA a TAACTGAAGGATACGCAGTTATGTATGGCTTTGGACTCT TTGTACACCACTGCCCCCCTACTAGGGCTGAGCATAATG CGGTTTTAACCGAAACACCGACCCAAACTGAATTATGAT ATTTGGTTCGGTTATTTAATATTTCAGTTTGTTATTCGT TTTTCTGTTCGGTCTGGTTTCAAGAGGCAAAAATTGTGA AAAACTGAACCAAATTATAGGTTTTCATATGTAAGTAGG TCCAAGCCAAACCCAATCCAATAGCTTCATTTTCATATG CAAGTCATCATCTACTTTAACCAAATAATTCTTTTCTTT TACTCTCTCCAAGTAAACCCCAATTAATTGCAATTTTTG TTAAATAAATTCTGTCTGTTCAGAAAAACCGAAATTTAT CCGAAATGTTTTCAGTTCTGAAAGTTTTATTTTTGGCTG TAATTCGGTTCGGTTTAATAAGAATTTTAGAAAACTCAG CTGGGCTTATTCGGTTTGGTTTACCCACATGCTCAACCC CTGGCTCCTATTGACCTCTTTCCTTAAATTTTTTCTAAT 153 WO 2013/039990 PCT/US2012/054789 TGCGATCAACTATCAAAAATGTTTCAGCTACATACTTGA TGGGGTGCCACGTATGAGAGAGAGACCAATCGGGGATTT GGTAACCGGTCTTAAGCAACTTGGAGCTGACGTAAATTG CTCGTCCACAAACTGCCCCCCTGTTCATGTAAATGCCAA TGGTGGTCTTCCTGGGGGAAAGGTATAAATATATCATCT CATTAAGTAAATACGAAAGAACAATTTCCTTCTTCTTTT GACTAGATCCATCATCATTGTATCGCTTCTAGGTTAAGC TATCAGGATCAATTAGTAGCCAATACTTGACCGCCTTGC TCATGGCAGCTCCCCTGGCTCTTGGAGACGTAGAAATCG AGATTATCGATAAACTGATTTCCATTCCTTATGTTGAGA TGACTCTGAAGTTAATGGAACGCTACGGTGTTTCTGTAC AACACACTAGCAGCTGGGATCGTTTCTTCATTCAAAGAG GTCAAAAGTACAAGTAGGTATTTTTATCGATTTACGAAT TAGGAAACCCTAGATTCTTTCAAACAAAAAACGAAAACC TTAAATGTCAATCAGGTCCCCGGGAAATTCATATGTCGA AGGCGATGCCTCGAGTGCCAGTTATTTCCTGGCAGGTGC AGCAATTACCGGTGGAACTATCACTGTAGAAGGTTGTGG CACTTCCAGTTTACAGGTATTTTTTAAAATTTCAGATTT TTTTTCGTATTAGGGATACAAAGTAACTTGTGATTGGCT GCTTGTTCTATATGAAAATTAAGGGAGATGTAAAGTTCG CTGAGGTTTTAGAAAAGATGGGAGCAAAAGTTAGCTGGA CGGAGAACAGTGTTACAGTGACTGGGCCACCACGAAATT CTCCTCGTGATAAGCACTTGCGTGCTATCGATGTGAACA TGAACAAAATGCCAGATGTCGCTATGACATTGGCTGTGG TTGCGCTTTTCGCTGATGGCCCCACTGCCATAAGAGACG GTAACTTCGTTCAATCTTCTCGTGAAAATAATAATTAAT ATTCTTCAAATAATCTGAAAGGACATTTTCTTGATTCCA GTGGCAAGTTGGAGAGTGAAAGAAA 82 Euphorbia Genom 1400 TCAACCAAATGATCCTTTTCTTTTATTTTCTCTAAGTAA heterophyll ic ACCCCAATTAATTGCAATTTTTGATGAACTCTGTTCAGA a AAAACCGAAATTTAGTCGAAATGTTTTCACTTTCAGTTC TGAAAATTCAGTTTTTAGGTGTAATTCGGTTCGGTTCGG TTCGGTAAGCATTTTTAGATAACTCAGCTGGGTTATTCG GTTTAGTTCAGCCAAATGCTAAACCCCTGGCCCCTATTG AGCTCTTTCCTCTAAATTTTTCTAATTGGAATTAACTAT CAAATGTGTTTCAGCTACATACTTGATGGGGTGCCACGA ATGAGAGAGAGACCAATTGGGGATTTGGTAACCGGTCTT AAGCAGCTTGGAGCCGACGTCAATTGCTCGTCCACAAAC TGCCCCCCTGTTCATGTAAACGCAAATGGCGGCCTTCCT GGGGGAAAGGTATAATATATAGTCTCATTAAGTAAATAT GAAAGAACAAGTTTTCCTCTTGTTTTGACTAGATCCATC ATTATTGTATCCCTTTTAGGTTAAGCTCTCAGGATCAAT TAGTAGCCAATACTTGACTGCTTTGCTCATGGCAGCTCC CCTGGCTCTTGGAGATGTAGAAATCGAGATTATCGATAA ACTAATTTCCATTCCTTACGTTGAGATGACTTTGAAGTT AATGGAACGTTACGGTGTTTCTGTAAAACACACTAGTAG CTGGGATCGTTTCTTCATTCAAAGAGGTCAAAAGTACAA GTAGGTATTTTCGTTGATTTACGAATTCCGAAACCCTCG ATTTTCGTTCAAACAAAAAAATGAAAACCCGGAATGTCA ATTAGGTCCCCGGGAAATTCATATGTTGAAGGCGATGCC TCGAGTGCCAGTTATTTCCTGGCCGGTGCAGCAATCACT GGTGGAACTATCACTGTAGAAGGTTGTGGCACAACTAGT TTACAGGTATTTTTTGTAGTTATTGCTTTGTGTTGGTTA AACTTTCAGAATTTTTTTCGTATTAGGGATACAAAGTGA 154 WO 2013/039990 PCT/US2012/054789 CTTGTTATATGAAATTTCAGGGAGATGTGAAGTTTGCCG AGGTTTTAGAGAAGATGGGAGCAAAAGTTAGCTGGACAG AGAATAGTGTTACAGTGACTGGGCCACCACGAAATTCTC CTCGTGACAAGCACTTGCGTGCCATCGATGTGAACATGA ACAAAATGCCAGATGTCGCTATGACATTGGCTGTCGTTG CGCTTTTCGCTGATGGCCCTACTGCCATAAGAGACGGTA ACTTCATTTAATCATTTCGCAGAAATAAGGCTTAATGCA TCTAGACCCCCTATAGTTGTCCCTAAAAACCTCTTAGCC CCCTGAACTTGTAAAAGTGGACCTTATGGCCCCCTAAAC TTATAAAGGTGGACCTTATAGCCCCTTGAACTTGG 83 Euphorbia Genom 584 TCTAGAGACGGTATTAACTCCTTTCTGATACATTACACT heterophyll ic TTTCTTGTGCTATATATTGTTTCAAATTTGATAATTCGA a TCATGCTTCAAATTTTGCACACAGCCGTAATCCATGGTT ATAAAATGACTATGACACTTGTCTTGTTACTGAAAAGTG CATACAGTAACAAAGCTGATGTTACTTCTTAGTTTACTC TAATAATGGTTGGACGGTCACTGGCGCACATCCCCATGG TTGGAAGTTGTGAATATTGTTGTCATAATGGCTTATGGA GCATCTTTTGGTACACTTCAGGAGTAAAAGACCACTAGT CCAGTATAGGGTTAATCACCTCTAGAACTAGTTAGTCAC ATATACTCGGAAAATTATTCATATTTTGTGGTTACATGC GTTCGTTTATCTGCATCTTGCCTAGTGTCTCCTCTTGAA ATCATTCATATATGTTCTTTTTTTCCCCTTCATCTGTTA CATGTTCAAAATATGCTTACAACGAAATTGGGTAACTTG ACCAGTTGCTAGCTGGAGAGTGAAGGAAACAGAAAGGAT GATTGCCATCTGTACAGAACTCAGAAAGGTTAGCCACA 84 Commelina cDNA 1250 CCCAAATCAAAATGGCCGCCAAAACCCTAGCTCTCTCGC diffusa CGTCGTCGCCGGCGGCGATCGCCGGAGCTCGCCGGAGCT CACCAGCGCCGCCGCCGGCGCTGGTACGGCTCGGATCCG GCCCAAAGGCGGCGCCTTTGGGCGCTCTGAGGGTCTTTG GGCGGCGGCCGGCGGCGCTGCGGGTCGCGGCGGCGGCGG CGGTGAAGACGGCGGCGGCGGCGGAGGAGGAGATAGTTT TGGAGCCGATTCGGGAGGTTTCGGGGGTTGTGAAGTTGC CCGGATCGAAGTCGCTGTCGAACCGGATTTTGCTGCTCG CGGCGCTGGCCGAGGGAACAACCGTAGTGGACAACTTGT TGAACAGTGACGATGTCCGCTACATGCTTGCTGCTCTGA GGACCCTGGGACTATCCGTGGAGGATGATGTTGCAACCA AAAGAGCGGTTGTTGAGGGATCTGGTGGCCACTTCCCAG TCGGTAACGAATCAAAAGAAGTTGAGCTGTTCTTAGGAA ATGCGGGAACTGCAATGCGACCACTAACTGCTGCTGTTA CAGCAGCTGGTGGAAATGCAAGCTACATACTTGACGGGG TGCCAAGGATGAGGGAAAGACCCATCGGAGATTTGGTTG ATGGCTTGAAGCAGCTTGGTGCTGATGCTGATTGTTTCC TTGGAACCAACTGCCCACCCGTTCGTGTAAATGCAAAGG GAGGTCTTCCCGGTGGAAAGGTGAAACTCTCTGGATCGA TTAGCAGCCAGTACTTAACTGCTTTGCTCATGGCAGCTC CTTTAGCCCTTGGAGATGTTGAGATTGAGATCATCGACA AGCTCATATCGGTCCCCTATGTTGAGATGACTCTGAAAT TGATGGAACGTTTTGGCGTTAAGGTAGAGCATTCTGAAA GCTGGGACAGGTTCCTCATCAAGGGTGGTCAGAAATACA AGTCTCCAGGTAAAGCTTATGTCGAAGGTGATGCATCGA GCGCTAGTTACTTCTTGGCCGGTGCTGCAGTCACTGGTG GCACTGTCACCGTTGAAGGTTGTGGTACGACCAGTCTGC AGGGTGATGTGAACTTTGCTGCAGTTCTTGAGAAAATGG GTGCAAAAGTTACATGGACTGAGAACAGCGTTACAGTTA 155 WO 2013/039990 PCT/US2012/054789 CTGGTCCACCACGCGATCCTTCGAAGAGAACAAACTTGC ACGGAATTGATGTTAATATGAATAAAATGCCAGACGTCG CTATGACACTTGCGGTTGTTGCACTGTTTGCTGACGGCC CT 85 Commelina Genom 9352 TTATTATTATTATTTTCATTGTTCCGGCTAGTTCTAGCC diffusa ic CCCCCACTGTCCATCTTCCCGTCTACCGCCCTCCTACAT CCTCTCTCACCCATTTCAGCCCCTCTTCCACACCTGACC ACTCACAGCCGACGGCCATCTAATCATACTTAGAGGACA TGTTCTAACAAAAAGATTAGGCTTCCACCTTTTAATACG AAAAAT TAAAGAAATAAT TATAAAAT T T TAAAT CAC T T T C GAAACAACACAAAAAAAAAAAATAAAAAAAT GCAACAT CCTTGATAATAAACTCAAACTAGAAAAATAAACTAAAAC AAAACCAAAATTTCAAAGTTGTTCTATAAAAAAAAAATA AAAAAATTCCAAGACTTGCTTCTTCGGCTCTTTTGTAGT CGATCGGTCTTCAAGACAAGTTAGCTGCTATGCTCGACT CTTGGAGAAATGTTCATTGCTTGAGCTTGAACCCACCTC AAACTCTTCGGATAGGCGGTCTCTTCTCCCTACTCCCAC TTTGTCTTCGGTTCCGAGGAAGAATGCCATCTTTTCTAC TTCCCCCATCTCTTTGGTTCTCTCAGCCACTCCCTCGGG GCTTTCTAGGATGTCTCGAGGCAGAACGAGAACCATGGT GTCTAGGTACTCAGTCGATGTTTGACCTCTCGGAGCTCG AAGCACGAGGAAGTCGAAACGATGAGAGAAGGTTTGTTT GTCACCGCTCGGCGTGGCGCAACGTTATCGTAGGTGATT CCGCGATTCAGGTTAAGCACAGCCTCGATCCAGCTAATG GATCAGAATAGGGGAGTCTCTTCACTGTAGATTTTTTTT CTTCTTGAGTTGTTTCACTTTGTTCTTATGGTGGGACCC TTCGGGGTCCCATATACGTAGGTGCGCACCGATGTTTGT TTGTATGGCTGTGGACGTCCTTATGTCAACTTTTTCGGC TTCCCTTCTTGGATCCCAAACACGAGAGGTGCACCGCCA CTGCATATGTGCACCACACTTTTTCATTCTACTAATACT AGGTCGTATAGTTCGGGTTGAAAAAAGAATAAAATAATA AGGGTGTTATACATATTTTTAATGATCTTAGTAAAGCTT TTGGTTTGATGATATAAAATGTGTTATTTTTGTTTGAAT ATATGACTACTTCATACATAACTTTTATGATGTCAGTAG GAATTTTGCATTGATTGTATAAATGTGTCATCTTGCTTA AATTAAACAAATTCATAACTGGTTTTATACATATTTTTT ATGATCTTACTAGGACTTCTGCATTGATTGTATAAAGGT GTTATTTTTGCTTGAATTTATGACTATTTTTATACATAA CTTTTATGATCTTAGCCTAAATTTTGCATTGATTGTATA AAGGTGTTATCTCGCTTGAATTTATGATTGGTTGGAATT TTGTGTATTTGCATTGTATATTGATTGTATAAAGGTGGC ATCTTGCTTGAATTCATGAGTAGTTTTATTCATAACTTT TATTATCTTAGTAGGACTAATGTATTGATTATATAAAGG AAGGAGTCATTTTACTTGAATTTAGAGAGGAGTTTTAGT TATGTGATTGCTGAGAAATGGAAATCATATTGTTTAATG GTTGGTAACTTGAACCTTGGGAGAGTGACTATGACTACT TTAGCATTTTACATATATTATAAGATTCAATGTTTGGTA GCAGAAAGTATATGCTTTTGAAAAGATCTTTCAGGAGCC TTGTATCACAATTAACAACTCAATCTGCTAAATCTGAGG ATAATTGGAGTGTTATACTTGTAGAATGTTAGATTGCTT ATTTACTTAAAAAATATTCGTCATATATAGGCTGTTCAT TGATAGCTATGGTATTTTCGGTCAATCTGTCTATTCAAC AAATAAATGGGAGTTTCATCTATCAATATTTATGATCTT GGTCATCAATAATGAATTTTCCTTAAGAGTTTGTATACT 156 WO 2013/039990 PCT/US2012/054789 TGATTGATCTGCTAACTCCTATTATGTCAATGCTAATTA CTATTGTCGGAATCTTAGTTCTTATAGGGGAATTGAAGA ATGTTGTTAGCTTTATTTTTCCGCAACTGATTGCCATTA ATTCGATCAGGGAACGACCGTAGTGGAGAACTTGTTGAA CAGCGACGATGTCTCCTATATGATTGCTTCCTTAAGGAC ACTGGGAATCTCTGTTGAACATGATGTTGCAACCAAAAG AGCACTTGTTAAAGGATCTGGAGGCCAATTCCCAGTCGG TAACGAATCGAAAGAAGTTAAGCTGTTCTTAGGAAACGC GGGAACTGCAATACGACCACTAACTGCTGCTGTTGCAGC TGCTGGTGGAAATGCAAGGTTTTTTATCACATTTTAAAT CCTGGCAATGTTTCTTCGTCTGCGTATTCCTAAATTCTA TTTTTCTGTTTATCTTCAGCTACGTACTTGATGGGTTGT CGAGGATGAGGGAAAGACCCATCGGAGATTTGGTCGATG GCTTGAGGCAGTTTGGTTGCGATGCTGATTGTTTCCTGG GAACCAACTGCCCACCCGTTCGTGTAAATGCGAAGGGAG GCCTCCGTGGTGGAAAGGTTTGTATGACAATTAGTTGAT CCAAGAGAGTTTCATGCCATGCTTCACCACCGATGTTTA CT CAACAAAAGATGCATAAGAAAT GAAAGCAAACCAC TC TATTCTGACCAAAGATCCGGTCGAATATGGTCATATTCG GTTGGAAATTCATATTTTCTGACTGAAAAACCAGTTGTA GTGATCGGTTGTCTCAGGCCTGGTCGCAAACTGAACCAC CCCTCAATTCGAAATATACGGTCAGAATAGGACCTGACT TTTGTAGTGTATGCCCGACAAGTGCTACGCCAGTCATTG GTATAAAAAAATTAGGGATATGCTTTAGTATCCATGGAA CAAGAGTAGCCCGGTTCGTTTTCCCAAATTAGTGCTAAA ATTTCAAGAATGAGTTATTCCTGTGCTCAAAAGATATAT ATCACTCCTGCCTAAACTTGATTTTAGCTTATCTTTGAT TAGAGAATTGATGTAGTTAATTCAATTTGCCTAATGATA GGAC TAACAAAAAT C CAAAAAAAAAAAAAC T T T GATAAT GCTAAAGACTATTAACTATGCTGATTCATTTTTTGTTTT TTAATTGATAAAGGTAGTCTTGTTTCCTATTTCCTTCTT GTTTTTTTATCAATAGAAACTAGGATTTGGAATTGGCTT GCTAAGACCCTATGATTAATTCGATTGAAAGAGTAACTA GATGCTGCTGGTGACTAGAAGATGAAGAAGGCGAGAGAT CGTATTCCATTCCAGTAAATTTAGTGGAATCAAGCAAAA TGATTCGTCATCGAAGACTAAATAGTATATCATAGGATC TTGTAAATTCAAAAGGGTTTTCATTTTTGAATTAGGATG TAACCGAAGTTGATGAACTTGTTTTATAAGGTCTAAGTT GTTTGTTCCTTTCACTTCCTGCAGATAACTTTTTTTCGA ATCTTCTTGCATTATGTGTATCTTTTGCTTAATATATAC ACTCGTAGATTAATGGCTTGGCATCTCTGTACGCAGGTG AAACTCTCTGGATCGATTAGCAGCCAGTACTTAACTGCT TTGCTCATGGCAGCTCCTTTAGCCCTTGGAGACGTCGAG ATCGAGATCATTGACAGGCTCATATCGGCCCCCTATGTG GAGATGACTCTAAAAGTGATGGAACGTTTTGGCGTTAAG GTAGAGCATTCCGATAGCTTGGATAGGTTCCTCGTCAAG TGTGGCCAGAAATACAGGTCAGTATTCAAGTGACTAAAT CACATTAACATTATCGGCATCACATGTGTGCACATTCTC TTCTTTGTGGCAGGTCTCCAGGAATAGCTTATGTCGAAG GCGATGCATCGAGTGCCAGTTACTTCTTAGCTGGTGCTG CAGTCACTGGCGGTATCGTCACCGTTGAAGGCTGTGGTA CCACCAGTCTTCAGGTATTTTTATTACTTTGAAACTGTA CAAAATCCTTTGTTTCTTATCGTCGAATAAAATGATGTT TCATCTTGTGTTTTCTGCTTAGGGTGATGTGAGATTTGC 157 WO 2013/039990 PCT/US2012/054789 TGAAGTTCTTGAGAAAATGGGAGCAAAAGTTACATGGAC TGAGGACAGTGTTACGGTTACTGGTCCACCACGCGATCC TTCAAAGAGAGGGAACTTACGGGGAATCGATGTTAACAT GAATAAAATACCGGATGTCGCTATGACGCTTGCAGTTGT TGCATTGTTTGCCGATGGCCCTACGGCTATAAGAGATGG TTAGTTATCGAAAGAAAAATTAGCTGCAAAAGCACTAAA GAATATCGAATTCAATACCAAATTGCACACGGTGTTTGA TAACCAACTATCTCAATCTACTTCTGTTTAGGGTCTATT TGATTTGAGAGACTTGAGAATTAACTTCTGTAGTTGGTA CTACAATCTAAATGGTGTAATGCGAACTGCGGCAGTTGA AAGTTTTTTAACATACAAGACGGATTCCGTGACTTATAA CT CAAC TACAT CAAAC TAAACAAGC GATACAAAAT TACT TCATTTAACTACTCCAGTTCAACTTTAACTACATCAAAC TAAATAGCCT CCTAGCAGCACAAAAACTC TAAT CAAC GT TGCAGCGTTCACAGAACAAGAAAGTGCCAACACTCACAC TTATATACGATATGCAGAATCTTTTTTATTCGAAATATC TTCTTTATTAACTTGTTTTCTCTATTTTTAGTGGCTTCT TGGAGAGTTAAGGAGACGGAGAGGATGATAGCCATTTGC ACAGAGCTCCGAAAGGTCGGTAATGTTCATTCTCTTGTA ACTTAGCTCTCGGTTTTCACATTCTGATTTTTCTATTGT ATTATGTTTTGGTTCAGCTCGGTGCTACAGTTGAAGAAG GGCCAGATTATTGCATTATCCATCCACCTGAAAAGCTGA ACGTAACGGCTATCAACACATACGACGATCACCGGATGG CAATGGCATTCTCTATTGCTGCCTGCGCCGACATCCCCG TTGCAATCAAAGACCCTGGTTGTACTCGCAAGACTTTTC CGGACTATTTTGATGTTCTGCATAGTCTTGCCAAGTACT GAACGAAACCTACGAAAGTTAATTTAGTCGACTTGGTTG GTGAATCAGTTTTCATGTAAAATTGTGTAATTCGTGTAT TAATAATCTTTTTCATACAAAATAAACACGGCAAAATTT TCTTTAGCAACAATTGAGTTGATCAAAACACAGCACAAT TATTTTGGTACAAAAATATTTTCATATATTAACATAACT AAC CAAC TAAC TAGT T T GT C TAGAAAATAAAAGC TAAGA AACAAAAATCATAACAACAAATCAGTAGGCAGTTTATAA CTGAAATAACTGCCCTCTAGTTTAAACACAACAAAGCCC TTTCCTTCCCTCCAAAACTAAAACTTCGACCGATTCTCC GAAAATTCCTTCTCTCCCACCCCCATTTCCTCCCATCTT CTAGGACTCCAAAGTCATCTTTCCCCTCTCCACCACAGC TGAACCTTGGTCAGTACAGCCCTGGAGATTGAGGGATAA TACTGTCAGTGCTATCGTTCGATGTTGGGACAATATCGA GTGCCTAAAGTCTTCTGTTCCTTTTATGCAGCAACACCT CAAAGAATTCCGGGTCCCATTTTCCTTTCCTTCCCCTTT GGAGTTTGTTGGTGATTGTTGTTTTTGTTTGTTTGGTGG TAGGAAATGATGGAGAGTTATGGGGTAAAGTTGGAGAGA TGTTGTGAGGAAATTGAAATGAAGAGGGTGGAGATGGAG ACCGAGGATGTCGAGCGAAAGAAATTGGAGGAGGAGAGA TCATTGACGCTCCTGTGGGATTTTGGGCCTAGCGTGGAC TAGTTGTAGACGGGTGGTTTGTCGAGATTTCTCCTGTAG AGCGTCCTCGGACTTTCTCTAGATTTCTTTGTGGGTTCT CAAGGAGGGTCCCCCATAAGGTTTGGGCCACTAGGATGA TGTCAACATGTGCGCTAGGTGAACCTAAGTTCGTTATGA CTTTGCGTGCGTCATATGATCCGTACTGGACGAACATGA GAAAGGAGTGAGACACATGCCCCTTGCTTAGTGCCAGTT GTACTTTTTGTAGGATTTGGGAATGGCTCCCAACTCTTG AGTCATTAGTGTGGTATTTGTGCCATTAATGCATGGATC 158 WO 2013/039990 PCT/US2012/054789 TTCGGGGGTGAGCCCTAAAGACGAGGTCCTACGATCGTG GGTGTTGGGGATTTAGCCATCCTAAGCATGGGGCTCCTG GATCTCTGAGGACATTTGTCACGGGGCCGTTGGATCCCC AGACATATCATGACACTCTTACAAGTGTCTGAGCCTGAC TGTTCTTGGAATCGCTGGGTCCCAAGACGGATTAGTCAT TATCCTCTATAGGCCCGTCTTGAAAAATGTTGAGGCCTT GTGCCAAATTAAAAATAGGGCTTTAACTAAATAAAATAA ATAAATTTTAATTTTTCGAATACATTAGTCTCTTCCTTA AAACAACAAAAACTATTAACAAAATAAAAAAATCAATAC AATACATTAAAATGAAGCTATGAAACAATCGGAGCAATC ACGAAATACCAACATAACAGTCTAAAATAGCAAAAATTA GTATATAACTCTTAAAAAATTACACAAATTATATAGCTA TACTTAAAAAATAAATAATTAAAAAATAAATTTCTAATA AGTGGAGGATATGGATTGGGCACCCTTAAAGTGGAGGCC CTGTGCTGTAGGGCTAATAGAACCCCCCACAGAGACCCC TTATCCTCTAGTTTGTCTTTGATTTTTACTCTTGTTGTC AATATAGAAGAACAAAAGAGAATAATCTAGTGTGCTTTT TCTTGTTGTTGTGGTTAATTTTATTGTTTTTGATATGGA AGAATGCAATAACACTATTGTGTTTCTTGTTGTTGTCGT CGTCAAAATTCTTCTCATTGTTCTTAGTGTTGACAGATG GTATTTGGTAATATTTATGAATTTTTTTTGTTGAAGTAA TATAATCCAATGTTCTTTTTGTTCATGTTAGATTCAACG AATGATCTAGTGCCTATGTTAGCATTGTGTTGATGTCTA GGAATGAAATGTTGTTATCGTCTAGTATTGATTATGATT TGTTATCAATATGCTGAATGAATTTGATTATTGATATAA TGTTTGGCATTACGCATTTTCAAAGTGCGAGGATTAAGT ATGATTTGTCGAGACGTAGGAAGCAATCCCTATAAGAGA TTATTGCTTTCTATAAATGATAGGTATTGTTAACTCTTC CTGATGTTTTCTCTCATTTCTCTAAAAATGTAGATTTGA TTCATATGTTAGAATTAGTGATGGTCATAGGGCGGGTTG GGGTGGGTAGGCACTCCCCCGCGACCCGCCCTGCTAAAT ACATATCCGCCCCGAAACTCAGCTCGCTTTGGGTTTTAA AAACATGACTCATGACCCGTCCCACAACGGAATGGGTCG ACCAGCGGGTCGCCCTGTTCACCAAGTTATTTATAAAAA AAAATATATGCATACTTATATAAAATATTATAGGCTTAT GTGCATGTATTTAATTCTATACATTTTAAATTATAATTA AAGTTTGTAGTTAAATCTATTAAAATTTTATTTTTTAAA CTATAAAGTACTAAACTATAATATTAAACTTATAAAAAA ATAGATATATTATACTATAAATATGCGGGGCGGGTACGC GTGGCAGGAATAACCATGACCTGTGACCCGCTCCGTCCC GTTGCGGGTCAAAAATAACCGCCCCACTACCCACCCCAC AACCCGTTTAGTTAACCTGTTTATAATCCATTCGGGTCG AAAACCCTATAGGACGAGTAATTTTTTGCCCCATGACCA TCCCTAGCTAGTTAGAACAATGTGTAGTTAGAGTAGGAT CTCAGCAAGGAACGGAGACTCTTTTCACACATTTTTAAA AAGTAATGATGGAAAACTAGATAAAGATCTCATACTCTT TTTGCGAATTCACAAAAAGTAATAAACTAAACTCATAGC AACAATTATTATCTTACATATAGATAATTCCTCGTATCT TGTTCATTCGCAATAAATTATTTTAGTTTTAAAGATACA TGCAACTAGAGTCACATGTATTCGACATATTTATAACCA ACGATTTTTCGTTCTGAATTATCACTTTTGTAAGATACA TTTGTCAACAATGTTGTACAAAATCGTTATATTGATCTA TATGCACTTGTAAGTACACAACATGGACTAACATATGCA TGTATATTATAAATATCAACTTGTACATATATGATATGG 159 WO 2013/039990 PCT/US2012/054789 TTGAACGTATATGCACTATACTTTTATGGCATGAAACTC CTTGTTCTTTGGGACATGCACATCTTGTCTTTTATTTTC TTAATATATATACTTTTCTTTTCTTAAGAAAAAAAATAA ATCTAGAGCTTGTTGTGGTATACATTTGCGTTCTCTGTC TTTCTTAAATATCTACTATACTAACGATCTATTGCTTGC TTAGTGCGGCAAAAGGAACCTTTTTTTTTTCTTAATATA TACTAAAATTTTTACTTCTCTTCTTAAATAAATAAATAA TAATAAAAAACTTGTTGCTACATACATTTGCACCCTACC TTTCTTCAATATCAGTTACACTTTCTACTCTTTTACTAA ATAGCTAGGAAAAAAAAATCTACGGCACAAAGGACAATT CTTACCTTTCACAAGGAAAAAAAAAAAATAAAAAAAAAT CATGTTATTTAAAAGACACTTTCAAGTTTGGGTACAAAT GGCGTCAACCTCGAACATTGTTTGAATCAGAATCGTTTC AATTATATGTTCCTAGTCCCTAGAGTAAGAAGTCACTTT TTGCTTAGCACGTGAGACTATCTTACAAGTGGACTACCC CAACACTCCACATCCCCCTCCACCTCCGCCATCGCCTTC TGTGCCTGTCTCTTCGCCTCCCTTGCCAACCCCGTGGCC TCCTCGACCGAAACCGCGCGAGTAGCGGCTGCGAGCATT AAGTTAGCTTTGTTGGCATTGCCCGCAGCTCTCTGAAAA CTATATTCCATCATGGAGGCGCAAAGTTCCATCTCGGCT TTTTCTTCTATGTATTGGGAGTGTTGAAACTCCTCCTTT GCAGAGGTTGCTTCGGCTTTGTAACTAGGTAGTTTGGGC TCGTAAAGTGCTTTGGCTTCCCGTAGACGAGACTCCGCT TTTGCGATATAGAGAGAAGCCTCTTGTAGTTGCATTTTT AAGGCTTTTCTTGGGTTTGTCTTTGCGAGGATGGAGATG TAGGATTTTGTGAGACAGTGAGGAAGTTTTGCCCACCAT GGCTTTGCTATTGTGCTCGGCATTGGTTTATTATTGATT GATTATCTTTAATCAATCAATATAATATATT 86 Commelina Genom 6205 ATATATTAAGCGAAGACGTTTTTGATACTTCTTATCGCG diffusa ic CCGCCTAAGCGCAACTTCATCAATCAAATATATATATTA TTAAACTCAATTCCTAATATATCTCTAAATCCTATTTGT GTATTTCTAGTTGCGGAGTTGTATTTGTACACTGAGTTT GCAGTATACTTTTGTATTTTCCATCTCTGACTTCTAATC GGAGACTGAGTGGTCAGCTAGGAAGTAATCATCATCAAT TACAAATATCACATGCAATGTTTTTTGAAAAAATTCTTG ACAAACATTTTCTTTTAGGGGGTTAATAATCTGTAAAAT CTCATAGATAACTCTTCGGTGTTGTTTTATAATATGATG ATACTCAAGGTGGTCATAATCTGAGGTGCTAAGTAGGAT CGGCAAAGGGTCCAGAGAATTGAAATCATGGAGCTAGAT AAGGATCGTAAAATTCTACAAAAATAATAAAATATAGTA TAAATAAATTATAAAGAATATTTTATATGTAAAAATAAT GTAAATATGTACACAATATTTTTTGTAAATTTATATATA AGCAATTTCAACATAAGGATTAATATTTACATGACAAAA TTATCGAATTTAATAATATAACACAATAAAAGTAAAATT GTGAGTCCTTAATTAATTAACTTAAGCATTCTTATAAAT GTAGATACTTTGTTTTGAAATTTATGTTGTTTAAATTAT CTAATATAATAGATATTTTCAAAATAATTTTTGTTCATG TCATGCATATAAATATTTTTATATTTTTTAAAAAAAGAA TTCATGCACAAAATAGTCTAATAAATTATTATTTTCAAT ATTATGGTGAGCATATTTTCTTTTGAGTTATTGTGGATT TGTGGTGAGCAAATTATTATTAATTAGTTTCAAATTTTA AAATATAATATGTATATGACATCTATTGCAACTAAACAT GATTTTATAAATTAATACAAATAATTTTAGGTTAATTAT TATTGACATCTTAATAATTTAATATATTGTTAAAATAAT 160 WO 2013/039990 PCT/US2012/054789 TTAATTTTATAATATATATTTTTAATATTGTGAAAA-AGT TTTTGTCATCTCTTTTTGAATTATAGATTTTTTAATTAC ATATATACATTTTTAATTATCTATCAGTATATACGCAAT AAATATCGATATATTTATTTTCATATCTATAA-AATGCAT ATCATAATTATTTATAGCAA-AAATGATTTTAA-AAATGAA TATACAATTATCCTATAAATATTTTAGAAATTT TTAGCA CACAATAATATATT TAATAA-AATT TAT CAT CATATAT TA AATAA-AATAAT TAC TATAT TATAT GAAA-AT GCAAATAAT AATATT TAAAAATC TCTCATGTAATAGGAAA-ATAATATC TAT TAT GT TAATC GAA-AT TTAGACAGT GAAGTATATC TA AC CATT TATAATGGTAAT TTACTTAGTTATATGATTATA TAGTTTTTTAATACTAAGAA-ACGTATATAAA-ACCCTATG AAGCATAA-ACATGATTTGAATCGATGGGGTCCCCCCATC TTGTTTGTTTGTTTTTTTTTTTCCAATCATTGTTTTTAT ATCCTAATATTCTTGATTTTTTTTTTTCCAA-ATATACTC TATTAGTTTTTCCATCCAAA-ATGCTGTCATCACATTATT T TAT TAATAT T TTAT CAATAAAATAT TGATATAAATAAA TGAAATAAAAACACTTTATTTTTTATTTATTAAAATAAT CATTTAAATTGTTTCTTACTAAA-ACCAA-ATAATTCTTAT AAAGTATACAT GATAAAAAGAAC TAAAGTATAAATATT T AAAA-ATAAA-AATATAAA-AGATATTT GAAGTTGTATAT GT AT CACAATTGTATAAATATTT TAT GAAAT TATATTTTAA AACCAATATTTTAATATAATAATATTTTATTAAAAA-ATA CAATAATTTTATAAGCATAATAATAATAATAATATTT TT TTTTTTCTTCACATTTCTCTATTCATTGTAATAATGTAT AATTAATATATTGTTTTTAGATGATACTATGGGTTGGTA TTATTTTAATTTTAATTTTTTTTTTGAATAAA-ACTAGGT GCATC TAGT GT GTTAT T TCAT TCAAAAATAT GTAAT CAT GATTACACTAATCTTGAAGACTATCTCGTGAAGAGAGAA CCC CACAT GATAAT CC C CCAAAAGAAAAT TATATACAAA AATGTGTAATAAAAAATATGTTATTTTAAATTTTTTGAA AAAGGAAAAGTATAATTAACT TAATATGCAAA-ATAAT TT TTGTATACAATAGATGGTTATTATCGTTTAA-ATACATAT GGAGTATAAT GTCCATGT GAAGCAT GGGC CATGTGCTAG TTTGCTAAAAATATAAATATTTTGCTTTAGTTTTAACTA TTTAATTCATTTTATTTATTACATTACTATTTAAATTGT ATTATTGTTTTAA-ATTAATTGAACATCGTATAACTTTTT T GAGT TCAAGAAAAT TATAA-AGAACAAC TTAAAAACACA ATTTTTTAA-ATTAATCTTTTATAATAAGACCATTTTAAA TT TATAC TAT TAT GTAAAATAGAGGATTC CC TAAATT TA ATATAT TAT TTAT TTAATAAATAAT TTACATAGAA-ACT T ATAAATAGACCTTAAAATTTATTTATTATATATATATGT ATATATATAAT CAGT TC CTAT GATT CCTAAAAATT TATT ACATTCAACAGTATTATATTTTTGATATTTTTTTTATTT TTCCTAGATCAAAAGTATATTTTTTTAACTTACATAAAT TTTCTTAAGATAGTTTCCCTTTATTTGAATCCTAATAAA ATATTTTTTCTGATTAATTTATTAATAA-AGATGATTAAA AATATTTGATTATGATCCTTTTTTTTCCTTGATCAA-AAG TATGGTTTTTTTTTTTTTTTAACTATAGAATTTTAAGAT AATTTTCCTTTATTTGAATCCTGATATAATTTTTCTAAT TAAT TTAT TAATAAATAT GAT TAAAAATAT T TGAT TAT G GT GCAAATTTAAAATTTTAGGCCAATAA-AAAATATTT TA ATTAAATAATGATATATTTATATTTGGTATAAGATATTT ____ ___________TTTTGTATAAAATATTTTTTTTACAAA-ATTAA-ATATTTT 161 WO 2013/039990 PCT/US2012/054789 CTATTTTATATTAATTTATTCTTTATTTTTTTAAATGTA TTTTTATTCTTTTATTGTTGAATAAGAGTTATAACTTTA TTGAACAACTTATATGATTTCAAA-AGTATACATATTATT CAACCT TTT GGGAT TCACAT GCC CAATCT CC CAT GC TAT TTTGCGATGTAAATATTTGCCGCTTAAGGTACGCATTTT TGTTTGACTTCTCTCCACAACACATATTGCTACGAGGGA TCAACTTAGAATAGACATGCATGTTGACTCACACTATGC ATTCTGCGGAGCCGATAATTCGGCGGATCATCTTTTCCT CTTGTATCCTATCGGAAGCTTGTTTTGATTTACATGTTA CT CCTATTC GT GCT CGAC CACAATT CAAGAGGT GT GGAT TAGTGGACGTCGGTGTCAACGTGTCGCCTGGTCGGCATT CTGCTGGACTCTTTGGAAGGCACGGAACCGCCTCATCTT T GAC CGT TAT CCTC CTAAGTT GC GAGC TATT CAGT GGGT GGTTCACTATCTTTTTGTGGATTGGACGTTGACCATTTA CTGTTTTAGGTTGGTCTTGCTTTGTTCGCTCTGTAGATA AT TATT CT GCTTTC TTTT TAGAGCC TGT GCAC CAA-ACCT CTTTTTGCAATGAAATGCTAGGTCTCCTAGTTTTCAAAA AAAAA-AAGTATATATAT T TTAAATAAA-AT TAAATAAAAA TATTTTCTTGACATTAAAATATTAATTTTTAATAGTAAT ATAATGTGATAGAT TTATAAAAATGTTTTAA-AT TTAC TA AATAGAGAA-ACTTGTTAAATATTTT TGGGTCATAAA-AAT TTAAAATAAAATAATTATAAAAACATAAT TATGTTAAAT TGTTTT TTTAAATATTAT TATATTAAATACGATATATAA TAAT GT CATAAAGT TATAC CAT CACATATACAC TAATAT TTCAATAAAAAAATATGTGTATGATTTTTTTTTCCTTCA TAATTTCTTTTACAGTGATATTTTTAATAAA-AGTAATTA AATAACAAGT TTGAGAGGTAT GAT GAGCT CCTGAGACAA TATTATATTTTCTATATTTTCAATTTGTATATATATGTT TTTATTTTATTTTTTTGAAATTATAAACATAGAATCTTA TTATTTTTAATCATTCAATAAATTCTAAGTGGTTTATAT TTAGTTCACTTTTTACTTATCATATTATTGTTAGGTTGC TTTCTTTCTTTATGATAGCAATTTTTTTAATTTTTTTTT TATATTAATGGTAAGATATGT TAAAAT TAACAC TTCATA TATATATAATATATATAT TAGAAAAAAT TAACAC T TCAT ATTGACTCTTCATGTGTTGATTGATTACTATCCAATACT TGCAATCTTAACGCTATTGTTAAA-AATCGTAACGGAACT ATGAAGCTTTGAACCAA-ACTACCTCCTCAGAGAAAGATT GATACAATTCCGGTGGTTTACTTTTTTATTAA-ATTATAA CATTGTAAGATGACTTGCTAATTACATACATTACATACA AT TATAACATAAATATAGTGAATAATAATAGAAACTAAA TAACCAACTAGGTAATAGCCTAGTTGGGATTTCGTCTCC AAAAGAGATGGAGGGGCCAGGTTTT GAGC CATGGTGACT GC GCTT GTCGCAAATTTT CCAAAGAAAAAGAGCATAAAT GCCATAGAATTATGACATAAACTACAATTTTTAATAATT CGAACAACAGTACT TAATAATATGC CATAATAT TATGAC ACAA-AT TACAGCAATTAATAATTCGAACAACTACAA-ACT GCAGTACTTAATAATTCGAATAACCACAATACTTAATAA TT CGAACAAAACAACATAATTATAT TAAT GCAT CACGTG TTTGCATGAAATTATGACATCATATATATATACACTAAT TC TTAACCT TACAATTTT TAT TTTT TTTT TGAAT TAT GA CATAAACTATTATATACACTAATTCTTAACCTTAAA-AAA AAACTATGACAACATGTATATATATATGCTAATTCTTAA CC TTACAAAAATAAATAAAT CT TGAAT TAT GACATAAAC _____ ____________TATAGTAC TTAATAAT T TGAACAAAACAACATAAT TACA 162 WO 2013/039990 PCT/US2012/054789 TTAATACATCACATGCTTGCATGCAATTATGACATATAT ATATACATACACACACAAACACACTAATTCTTAACCTTA AAAAAAATAAAAAATCTTGATCTATTGAAAGCAACAAAA TAGCATATTAACTTTGGTATAGTACACAAAATTATGACA TAAAATATTAACTTTGCTGTAAGGCTTTTAAAAAATAAC TTCTCTATCCCAATTTAATAATAATGATAATGATAATGA TAATGATAATAATAATAATAATAATAATAGTAGGAGCAG CAGCAGGATTAGATCTAGATTCTTTTATGACTTCACCAT ACAGTGATTTTACATTATGAATAATAGGATTTGATTCTC TTAACTTAATAATAATATTAATAAGAATTAGATCTAGAT TCTTTTATGACTTCACCGTACAGTGATTTGATTTTACAT TATGAATAATAGGATTAGATTCTCTTAACTATAATAATA ATAATAATATATTTGGTAATGCGACTTTATAGAAAGGAC CCGAATTTAATTCGGAGTTCCGTATAGTTAAACTGTGTC TCTCACTAATAGTAAATATATATATATTTGCATTCTCAC TGGTCTCTCAAACATCAATGGCCAAAACCCAACACTTCC ACTCATCCTCGCCGGCGGCGATGGCCGGAGCATCCCCTG AGGTCGTTCTCCAGCCCATTCGGCAGATATCCGGGACGG CGAAGCTCCCCGGATCGAAGTCTCTGTCGCAGAGGATAC TGCTCCTTGCTGCGCTCTCTGAGGTGAGGATTGTTCGTT TTATGGTAAAAATGAATTCTTAGTAGTTTTGCTAATGTA ATTGAGCTGCATTGATATGAATGCATATACTTGGTAACC TAGTGTTAGTTTTCCAAGAATGTTGGAGATAGTTTGACT TTTTTTTTAATACAGAAATTTTATTATATTATTATATAA GGGTGTTACTACTACTACTACTACTTCTACTACTACTAC TACT 87 Commelina Genom 818 CTTAAAAGCCTAAAATCCACCTAACTTTTTCAGCCAACA diffusa ic AACAACGCCAAATTCAGAGGAAGAATAATGGCTCAAGCT ACTACCATCAACAATGGTGTCCATACTGGTCAATTGCAC CATACTTTACCCAAAACCCAGTTACCCAAATCTTCAAAA ACTCTTAATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNN GGATCAAACTTGAGAATTTCTCCAAAGTTCATGTCTTTA ACCAATAAAAGAGTTGGTGGGCAATCATCAATTGTTCCC AAGATTCAAGCTTCTGTTGCTGCTGCAGCTGAGAAACCT TCATCTGTCCCAGAAATTGTGTTACAACCCATCAAAGAG ATCTCTGGTACTGTTCAATTGCCTGGGTCAAAGTCTTTA TCCAATCGAATCCTTCTTTTAGCTGCTTTGTCTGAGGTA TTTATTTCTCAACTGCGAAAACAATCTCTATTTGATATT GGAATTTATATTACATACTCCATCTTGTTGTAATTGCAT TAGTACATACTTATGTTTTGACCTTTGTTCGTTTGTTTG TTGAATTGGTAGTGTTGAGAATTTGAATCTAATTATTTG TTTTTCCATGTGAATTTAATCTGATTAAATCCACTTCTT ATTTATGTTAAGTTGCAATGATGTTTGCCAAACGGTTAT CATTGAAGGATAAGTTCGCCTACTTTTGACCCTCCCAAC TTCGCGTTGGTAGAGCCATTTTATGTTATTGGGGGAAAG TAGAAAGATTTATTTGTTTTGCCATTCGAAATAGTAGCG TTCGTGATTCTGATTTGGGTGTCTTTATAGATATGATA 88 Commelina Genom 127 TGATTAATTTGATGTATATATATAGTTGAAGAGTTGTAC diffusa ic TTGTACGCTGAGTATGTATGTAGTATATTTGTACTCGGA GACTAGCTAAGTTACCATGTAATTAATTATCCATCATCA ATTACAAAAA 89 Digitaria cDNA 783 ATTAATTCTTCGTCTTTTTGTCTGCAAATCACCAAGAAA sanguinalis CATAATGGCAGTTCACATTAACAACATATCCAACTTTAC TTCCAATCTCACCAATACCCACAATCCCAAACCCTTCCC 163 WO 2013/039990 PCT/US2012/054789 CAAATCATTACCATCATCTTTTGGATCCAAGTTCAAGAA CCCCATGAATCTTGCTTCTGTTTCTTGCAACCAAAACTT TCAAAAAGATCACTTTCTGTTACAGCTTCTGTTGCCACC ACAGAGAAGTCCTCAGTGGAGGAGATTGTGTTGAAGCCC ATTAAAGAGATTTCTGGAACTGTTAATTTACCTGGATCT AAGTCTCTGTCTAATCGGATCCTTCTTTTAGCTGCTCTT GCTGAGGGGACTACTGTTGTAGACAACTTATTGAACAGT GACGATGTTCATTATATGCTTGGGGCATTGAGAGCTCTA GGGTTGAATGTTGAGGAAAATGGTCAGATTAAAAGAGCA ACTGTGGAAGGGTGTGGTGGTGTGTTTCCGGTGGGTAAA GAAGCTAAGGATGAAATCAAACTATTTCTTGGAAATGCA GGAACTGCTATGCGTCCGTTGACTGCTGCAGTTACTGCT GCTGGTGGAAATTCAAGCTACATACTAGATGGTGTTCCC CGAATGAGAGAGAGACCAATTGGTGATTTAGTCACAGGT CTTAAACAACTCGGTGCAGATGTTGATTGCTTCCTTGGT ACAAATTGCCCACCTGTTCGTGTAGCTGCCAATGGAGGC CTTCCTGGTGGAAAGGTCAAACTGTCGGGATCTATTAGT AGT 90 Digitaria cDNA 679 GGATTGGAGGGCTACCTGGCGGCAAGGTTAAGCTGTCTG sanguinalis GTTCAATCAGCAGTCAATACTTGAGTGCCTTGCTGATGG CTGCTCCTTTAGCTCTTGGGGATGTGGAGATTGAGATCA TTGATAAACTAATCTCCATTCCCTATGTCGAAATGACAT TGAGATTGATGGAGCGTTTTGGCGTGAAAGCAGAGCACT CTGATAGCTGGGACAGGTTCTACATCAAGGGAGGTCAAA AATACAAGTCCCCTAAAAATGCATATGTGGAAGGAGATG CCTCAAGTGCTAGCTATTTCTTGGCTGGTGCTGCAATTA CTGGAGGGACTGTGACAGTTGAAGGGTGTGGCACCACCA GTTTGCAGGGTGATGTGAAATTTGCTGAGGTTCTGGAGA TGATGGGAGCGAAGGTTACATGGACTGAGACAAGTGTAA CTGTTACTGGTCCACCGCGGGAGCCATTTGGGAGGAAAC ACCTAAAACCCATTGACGTCAACATGAACAAAATGCCTG ATGTCGCAATGACTCTTGCTGTGGTTGCCCTCTTTGCTG ATGGCCCAACCGCAATCAGAGATGTGGCTTCCTGGAGAG TGAAGGAGACTGAGAGGATGGTTGCAATCCGGACTGAGC TAACTAAGCTTGGAGCATCAGTTGAGGAAGGTCCAGATT ACTGCATCATCACGCC 91 Digitaria cDNA 638 TGTAGAGGGTGATGCTTCAAGTGCAAGTTACTTCTTGGC sanguinalis TGGAGCTGCTATAACTGGTGGCACTATCACTGTTGAAGG TTGTGGAACAAGTAGTTTGCAGGGTGATGTGAAATTTGC GGAGGTTCTTGGACAAATGGGGGCTGAAGTAACATGGAC CGAAAACTCTGTTACAGTGAGGGGTCCACCGAGGGGTTC TTCTGGAAGTAAACATTTGCGTGCTGTAGATGTTAACAT GAACAAAATGCCCGATGTTGCCATGACTCTTGCCGTGGT TGCTCTCTATGCAGATGGTCCTACAGCCATTAGAGATGT TGCTAGCTGGAGAGTCAAAGAAACCGAAAGGATGATTGC CATTTGCACAGAACTCAGAAAGTTGGGAGCGACAGTTGA AGAAGGGCCTGACTACTGTGTGATCACTCCACCTGAGCG GTTGAATGTGGCAGCAATAGACACATATGATGATCACAG GATGGCCATGGCTTTCTCCCTTGCCGCTTGTGCAGATGT TCCTGTCACCATCAAGGATCCTGCTTGCACTCGTAAGAC GTTTCCCGATTACTTTGAAGTTCTTCAGAGATTCACCAA GCATTGATGTTTTCAATAGAGTTTTTGTTTCATTTGTAA GGTGCCAAATATGT 92 Digitaria cDNA 605 CTTAGCTGGTGCTGCCATCACCGGTGGCACCGTTACGGT 164 WO 2013/039990 PCT/US2012/054789 sanguinalis GGAAGGTTGTGGGACAAGTAGTTTACAGGGGGATGTAAA GTTTGCTGAGGTCCTTGGACATATGGGCGCAGAAGTAAC CTGGACAGAGAACTCAGTGACAGTGAAGGGCCCACCAAG AAACGCTTCCGGAAGGGGGCACTTGCGTCCAGTCGATGT TAACATGAACAAAATGCCCGATGTTGCCATGACTCTTGC CGTGGTTGCTCTCTATGCAGATGGTCCTACAGCCATTAG AGATGTTGCTAGCTGGAGAGTCAAAGAAACCGAAAGGAT GATTGCCATTTGCACAGAACTCAGAAAGTTGGGAGCGAC AGTTGAAGAAGGGCCTGACTACTGTGTGATCACTCCACC TGAGCGGTTGAATGTGGCAGCAATAGACACATATGATGA TCACAGGATGGCCATGGCTTTCTCCCTTGCCGCTTGTGC AGATGTTCCTGTCACCATCAAGGATCCTGCTTGCACTCG TAAGACGTTTCCCGATTACTTTGAAGTTCTTCAGAGATT CACCAAGCATTGATGTTTTCAATAGAGTTTTTGTTTCAT TTGTAAGGTGCCAAATATGT 93 Digitaria cDNA 605 CTTAGCTGGTGCTGCCATCACCGGTGGCACCGTTACGGT sanguinalis GGAAGGTTGTGGGACAAGTAGTTTACAGGGGGATGTAAA GTTTGCTGAGGTCCTTGGACATATGGGCGCAGAAGTAAC CTGGACAGAGAACTCAGTGACAGTGAAGGGCCCACCAAG AAACGCTTCCGGAAGGGGGCACTTGCGTCCAGTCGATGT TAACATGAACAAAATGCCCGATGTTGCCATGACTCTTGC CGTCGTTGCTCTCTATGCAGATGGTCCTACAGCCATTAG AGATGTTGCTAGCTGGAGAGTCAAAGAAACCGAAAGGAT GATTGCCATTTGCACAGAACTCAGAAAGTTGGGAGCGAC AGTTGAAGAAGGGCCTGACTACTGTGTGATCACTCCACC TGAGCGGTTGAATGTGGCAGCAATAGACACATATGATGA TCACAGGATGGCCATGGCTTTCTCCCTTGCCGCTTGTGC AGATGTTCCTGTCACCATCAAGGATCCTGCTTGCACTCG TAAGACGTTTCCCGATTACTTTGAAGTTCTTCAGAGATT CACCAAGCATTGATGTTTTCAATAGAGTTTTTGTTTCAT TTGTAAGGTGCCAAATATGT 94 Digitaria cDNA 510 TGTAGAGGGTGATGCTTCAAGTGCAAGTTACTTCTTGGC sanguinalis TGGAGCTGCTATAACTGGTGGCACTATCACTGTTGAAGG TTGTGGAACAAGTAGTTTGCAGGGTGATGTGAAATTTGC GGAGGTTCTTGGACAAATGGGGGCTGAAGTAACATGGAC CGAAAACTCTGTTACAGTGAGGGGTCCACCGAGGGGTTC TTCTGGAAGTAAACATTTGCGTGCTGTAGATGTTAACAT GAACAAAATGCCCGATGTTGCCATGACTCTTGCCGTCGT TGCTCTCTATGCAGATGGTCCTACAGCCATTAGAGATGT TGCTAGCTGGAGAGTCAAAGAAACCGAAAGGATGATTGC CATTTGCACAGAACTCAGAAAGTTGGGAGCAACTGTCGA AGAAGGGCCAGATTATTGTGTTATCACTCCGCCAGAGAA GTTGAACGTGACAGCCATCGACACATATGATGATCACAG AATGGCCATGGCATTCTCCCTTGCTGCATGCGCAGACGT TCC 95 Digitaria cDNA 510 TGTAGAGGGTGATGCTTCAAGTGCAAGTTACTTCTTGGC sanguinalis TGGAGCTGCTATAACTGGTGGCACTATCACTGTTGAAGG TTGTGGAACAAGTAGTTTGCAGGGTGATGTGAAATTTGC GGAGGTTCTTGGACAAATGGGGGCTGAAGTAACATGGAC CGAAAACTCTGTTACAGTGAGGGGTCCACCGAGGGGTTC TTCTGGAAGTAAACATTTGCGTGCTGTAGATGTTAACAT GAACAAAATGCCCGATGTTGCCATGACTCTTGCCGTGGT TGCTCTCTATGCAGATGGTCCTACAGCCATTAGAGATGT TGCTAGCTGGAGAGTCAAAGAAACCGAAAGGATGATTGC 165 WO 2013/039990 PCT/US2012/054789 CATTTGCACAGAACTCAGAAAGTTGGGAGCAACTGTCGA AGAAGGGCCAGATTATTGTGTTATCACTCCGCCAGAGAA GTTGAACGTGACAGCCATCGACACATATGATGATCACAG AATGGCCATGGCATTCTCCCTTGCTGCATGCGCAGACGT TCC 96 Digitaria cDNA 477 CTTAGCTGGTGCTGCCATCACCGGTGGCACCGTTACGGT sanguinalis GGAAGGTTGTGGGACAAGTAGTTTACAGGGGGATGTAAA GTTTGCTGAGGTCCTTGGACATATGGGCGCAGAAGTAAC CTGGACAGAGAACTCAGTGACAGTGAAGGGCCCACCAAG AAACGCTTCCGGAAGGGGGCACTTGCGTCCAGTCGATGT TAACATGAACAAAATGCCCGATGTTGCCATGACTCTTGC CGTCGTTGCTCTCTATGCAGATGGTCCTACAGCCATTAG AGATGTTGCTAGCTGGAGAGTCAAAGAAACCGAAAGGAT GATTGCCATTTGCACAGAACTCAGAAAGTTGGGAGCAAC TGTCGAAGAAGGGCCAGATTATTGTGTTATCACTCCGCC AGAGAAGTTGAACGTGACAGCCATCGACACATATGATGA TCACAGAATGGCCATGGCATTCTCCCTTGCTGCATGCGC AGACGTTCC 97 Kochia cDNAC 1548 ATGGCTCAAGCTACCACCTTTAACAATGGTGTCAAAAAT scoparia ontig GGTCATCAATTATGCGCCAATTTACCAAAAACCCACTTG CCCAAATCTCAAAAAGCTGTCAAATTTGGATCAAACTTG AGATTTTCTCCAAAGTTGAAGTCTTTCAACAATGAAAGA GTTTCTGGGAAATCATCAGTTGTTTTTAAGGTTCATGCT TCAGTTGCTGCTGCTCCCTCAACTTCCCCAGAAATTGTG TTGCAACCCATTAAGGAGATTTCTGGCACTGTTCAATTG CCTGGTTCTAAGTCTTTATCTAATCGAATTCTTCTTTTA GCTGCTCTTTCTGAGGGTACAACAGTACTTGACAACTTG CTATATAGTGATGATATTCGCTATATGTTGGATGCTCTA AGAACTCTTGGGCTCAACGTAGAGGATGATAATAAGGCC AAAAGGGCAATCGTGGAGGGTTGTGGCGGTCTATTTCCT GCTGGTAAAGAGAATAGGAGTGAGATTGAACTTTTCCTT GGAAACGCGGGAACGGCAATGCGCCCATTGACAGCTGCA GTTGCCGTTGCTGGAGGAAATTCCAGTTATGTACTTGAT GGAGTGCCAAGAATGAGGGAGCGACCCATTGGGGATCTG GTAGCTGGTCTGAAGCAACTGGGTGCAGATGTTGACTGT TTTCTTGGCACAAATTGTCCTCCTGTAAGAGTAAATGCT AAAGGAGGTCTTCCAGGGGGCAAGGTCAAGCTCTCAGGA TCAGTTAGTAGCCAATATCTTACTGCGCTACTCATGGCT ACCCCTTTGGCTCTTGGAGATGTGGAGGTTGAAATCATT GATAAATTGATTTCTGTCCCTTACGTAGAGATGACAATA AAGTTAATGGAACGGTTTGGAGTGTCAATAGAGCATACT GCTAGCTGGGACAGGTTTTTGATCCGAGGTGGTCAGAAG TACAAATCTCCTGGAAATGCATTTGTTGAGGGTGATGCT TCAAGTGCCAGTTACTTCTTAGCAGGGGCCGCGATCACT GGTGGGACTGTGACTGTTGAGGGTTGTGGAACAAGCAGT TTGCAGGGTGATGTTAAATTCGCGGAGGTTCTTGAGAAG ATGGGTTGCAAAGTTACATGGACAGAGACCAGTGTCACT GTAACTGGACCGCCCAGGGACTCATCTGGAAGAAAACAT TTGCGTGCCATCGATGTTAACATGAACAAAATGCCAGAT GTTGCGATGACTCTTGCTGTTGTTGCCCTATATGCAGAT GGGCCCACAGCTATCAGAGACGTTGCTAGCTGGAGAGTG AAGGAAACAGAAAGGATGATTGCCATCTGTACAGAACTC AGAAAGCTTGGAGCAACAGTTGAGGAAGGACCTGATTAC TGTGTGATCACTCCACCAGAAAAACTAAACGTAACCGCC 166 WO 2013/039990 PCT/US2012/054789 ATCGACACATATGATGATCATCGAATGGCCATGGCATTC TCTCTTGCTGCCTGTGCTGATGTTCCTGTCACTATTAAG GACCCAGGCTGCACCCGCAAGACCTTCCCAGACTACTTT GACGTCTTGGAACGGTTTGCCAAGCAT 98 Kochia Genom 7037 TTTTCATGAAATAAATCTTGATCCTTCATTCAAAATCCA scoparia ic ACGATCAAAATTGCTTCTCACGTTTCTCATTTTAAGGGT GCTTCTCATTTGATCCTAAATCTATATACATATGTAAGT ACCTTGAATGCCATGGAATTGAAATTTTAAATTATGTGT TGGTTGTGAATGGGGTTAATGAAGTAGATAGAGTAGGCT GACAAATATTCCAAGGGGTACCTACAGCTACTCTTGGTC ACTAAGTCATTGTTCTGTTTTTAGATTTTAATTGCTTTC CCTTATGGTTTTTTCAGTTATGTACTTGATGGAGTGCCA AGAATGAGGGAGCGACCCATTGGGGATCTGGTAGCTGGT CTGAAGCAACTGGGTGCAGATGTTGACTGTTTTCTTGGC ACAAATTGTCCTCCTGTAAGAGTAAATGCTAAAGGAGGT CTTCCAGGGGGCAAGGTAGAGTAAATTTCTTGTAGATTA ACTTTGTTGATAATTCACTCATTAATATATCAATGAGAC ATCCTCAAAAAATAACTCTGTCCTGTTTTCCTGTCATTA AGCTCTGTTACATAACTTACATTATTTTAAAGCATTTTG ATGGAATGTATCTGCAGGTCAAGCTCTCAGGATCAGTTA GTAGCCAATATCTTACTGCGCTACTCATGGCTACCCCTT TGGCTCTTGGAGATGTGGAGGTTGAAATCATTGATAAAT TGATTTCTGTCCCTTACGTAGAGATGACAATAAAGTTAA TGGAACGGTTTGGAGTGTCAATAGAGCATACTGCTAGCT GGGACAGGTTTTTGATCCGAGGTGGTCAGAAGTACAAGT AAGTCACTCTTCTTTTACTTGCATGTATTGAACGTCATT CCATTGGTAGACTGATGCAGCATTAATAATATGTCAGAT CTCCTGGAAATGCATTTGTTGAGGGTGATGCTTCAAGTG CCAGTTACTTCTTAGCAGGGGCCGCGATCACTGGTGGGA CTGTGACTGTTGAGGGTTGTGGAACAAGCAGTTTGCAGG TATGATCCAAAGCCTCACTTCAATAAATTTTCAAGTACA CATTCGTTTTACTTCCTCCGTTTTGTATTACTCGCACCG GTTTCCATTTTGGGAAATTTGCGAATACTTGCACCACTT TGCTTTATTCCCTTTTTTGGCAATTTATTTTGTTTGAAA TGACCATTTTAGCCTTATTGTTTTTCCCCACATGGTGGG ATCAAAGGAATTAACACCATAAAACACACCTCCTTTATA CCCCACCAACTTAATCACACTACCCTTCCCTCAACTAAT TATACCAACAAAAAAACGCCTTGGAGTCCGCAATAATGA AAGTGGTGCGAGTAATATAAAACGGAGGAAGTATTTATT TTTTAGATTAACTGTTGTAACCATTTTTTGGTTAATTTT GAGGCTAAAGTATGGCCTTTTGACAATTAACTTTCAATA TTAATCTCTAATGTGGTGTAAAGTCATCCATTTTAATAT CAGACAATTGTGTTTGACTCCCAAAAAAGGATAATTTAC TTCTTATTGTTTTGTGACTGCCAAAAAGGATCACTTGAA TGTCATGGATTGTTTAATCACCTATTTAGGCATTGTTGT GTTGTGATTCACCTCATCTTTAGGTCCAATAGATTTTGG CTGAATCTTACTTGTGACTGCCAAAAAGGATCACTGACA ATTTACTTGTTTAACGGATTTTACTCAGGGTGATGTTAA ATTCGCGGAGGTTCTTGAGAAGATGGGTTGCAAAGTTAC ATGGACAGAGACCAGTGTCACTGTAACTGGACCGCCCAG GGACTCATCTGGAAGAAAACATTTGCGTGCCATCGATGT TAACATGAACAAAATGCCAGATGTTGCGATGACTCTTGC TGTTGTTGCCCTATATGCAGATGGGCCCACAGCTATCAG AGACGGTATTAACTCCTTTCTGATACATTACACTTTTCT 167 WO 2013/039990 PCT/US2012/054789 TGTGCTATATATTGTTTCAAATTTGATAATTCGATCATG CTTCAAATTTTGCACACAGCCGTAATCCATGGTTATAAA ATGACTATGACACTTGTCTTGTTACTGAAAAGTGCATAC AGTAACAAAGCTGATGTTACTTCTTAGTTTACTCTAATA ATGGTTGGACGGTCACTGGCGCACATCCCCATGGTTGGA AGTTGTGAATATTGTTGTCATAATGGCTTATGGAGCATC TTTTGGTACACTTCAGGAGTAAAAGACCACTAGTCCAGT ATAGGGTTAATCACCTCTAGAACTAGTTAGTCACATATA CTCGGAAAATTATTCATATTTTGTGGTTACATGCGTTCG TTTATCTGCATCTTGCCTAGTGTCTCCTCTTGAAATCAT TCATATATGTTCTTTTTTTTCCCCTTCATCTGTTACATG TTCAAAATATGCTTACAACGAAATTGGGTAACTTGACCA GTTGCTAGCTGGAGAGTGAAGGAAACAGAAAGGATGATT GCCATCTGTACAGAACTCAGAAAGGTTAGCCACATTCTT TAATCTTGTAGTAAAAAATAAAGTTGCCTGTTTCATGTA AGTTGATGTTAATTCGGACTTTTAAAATTTTCAGCTTGG AGCAACAGTTGAGGAAGGACCTGATTACTGTGTGATCAC TCCACCAGAAAAACTAAACGTAACCGCCATCGACACATA TGATGATCATCGAATGGCCATGGCATTCTCTCTTGCTGC CTGTGCTGATGTTCCTGTCACTATTAAGGACCCAGGCTG CACCCGCAAGACCTTCCCAGACTACTTTGACGTCTTGGA ACGGTTTGCCAAGCATTGAGCGGCTATCTGCAGATTTTT CATAAAGTATGCACGAAAGTTTCAATTTAAGAAGATACC GAGTTGATTATATGCTTTCCGCATAAGTTATTGTCACAT TTTTTGTATTATGTTTGTAAGATCTTAGGCAATAAGATA TACTGTTAGAAATTATGTGTATCTGATTATTTAGAGATG TATACTTGGGTCAGTTGAAATTGTACGAGAAAGGTCTGG ATTTCGAAAAAAATGTGATCCAGACATTAGTGTGGTCTG AACTGAAGCAAGTACTCCCTCCGTCTCATAATTCTCACA ACTCTTGCTATTATTTGTGAGAAATAAAATATTCAAGTG TTGCGAGAATTGTGTGACAGCGGGAGTAGCAACTTTTCA AGTTTGGAATTAATTTTGTGATGTGAGTTTTTTGTGTAT TCTTTGTTTTCCATCAAACCCTCCTCCAAAGTACAAACC CAATTCATGGTATGGTTGATGCAACAGCAATATGTCAAA ATCAGTGTTTGTGATGTTGGCTTCTCTACTTCATTATCT CTTCTTGTTCAGTATGATTTCGCAATCTCTTCCCGTCAA AATCCCTTCTCTGATAAACGCGGAAATCGTGTCTTCCCC TCAGTGTGTATCCACCTCTTAAAAATTTGTTGAGAGTTG AAATGTGCTGCCACTGGATTCATCCTTTAGGGCGAATTT TGAACGGATTTTAGGTGGTTAGGATTCAATCCCTGTCAA TTATTGTTACGGGAATTAGACACGCGTTCTGCCTTACCA ACCCCATTTTTTTTGTCACTATATCAAGTATCCATTGCT AGTTGTAGTCATGTAGTAGGGTCTGAAATCTAAAGCTAA GTAGCAAGATTGCAACAACAGGAACAGCAAATAAATCTA GACTTTTGAGGTTTGTTTTTTTTTTTTTTTTTTTTGACT TTTGAGCTTAGTTTGTCATATTGGTTAAATAATAAGTTA CTGTAAATAGATTCAGTTTTAATTTTGTTGTTAGTGTTA GTGTGTTTGGCGGTGGTTGGTGGTTTATCTATCTTTTCC ATTACTAGTGTCATAATTCAGAGAAGATCTACTTTGTTG ATGATAATCTGTGTAGTATTGAATCAGACATCAAATCAA TTCGTAGAATTTGTTGAATCTAGTATTAGCAAGGTCCCC TTGTAGACGGCTGCAGATGACAGCGATTCATGAGACGAG AGTATTTTTTAATGTCAGATTTTACAAGCGATTATAGTG ATGTTGAATTAGAATTATTATTAGGTTCAATTTTCATTA 168 WO 2013/039990 PCT/US2012/054789 TCTTTGTTATTTTTTTTATCTCTGTTGTAAATGTCGTAT GACTTGTTATTTTTTATCTCTGTCGTAAATAGTTACTTT TCCCCTAGAAAAAAGTCAGAACTGACATACGACTACCAC TTCAGTTCGTAATTTATAATTATAATTATTATTATTCTC CCTTGTTTTACTTTAGACAA-AAACAGTAATTGCAA-ATAA TAATT TAT CAT GAAT CAT GAT GAAAAATT GAAAAT GGAA TAGAAGAAGT GAAGAACT GCC TTAGTTTAAAAAAAA-ACG AAGATTAGATAGAATTACACT GAAGGTAAGAATATAGTG AGAGTC TAAT TAGT GGTTAAT TAAC TATC TAGGCTTAAT TCTCAATCACTTTTTTAAAA-ACTTGTGCTATCACTTTTG CCCTTCAATTAGGGTTCATTAGTGGGGTTAA-ATAATGCA CAATAGGGTT TGCATTATATGACAACATTAGAGTGAGGG ATAACTCAAGTGGTTAA-AACTCTTCTCTCGATTTCAGAA TATTCTGAGATCGATTCTCATTTCCATTCTAGTGGCTCT CT TAACAC CAAA AAAA-ATAAAAA-ATAA-AAA-AT TAGT GG GGTTAAATAATGCACAATAGGGTTT GCAT TATATGACAA CATTAACTTGTTAACTAAACGAACACATACATGTGTAAA TAAA-AC GATAAGAAAGTT GTT CTATACTTATTCAA-AGGT CT CGAGTTC GAGCC CT GAGAAT GAAGAAGCAT GT GTTAA AAGAACTAATTTCACAATTGTGACTTAACTCGATTCGAA TCCAAATTAATCAAATCCTAACGGATTTCGAATATTGAA TACGCTTGTGTAA-AACATAACATTTATGAACTTGTTAAG TAGTTTAATGGAGTAGTTAATAATC CTTTATAACATAGG TAT TAT TAAAGT GATAAAGTAAACAAGAT TGTAAGAC GA CAATAAGACCAATCAAAGTTGGGGT CAAATGAT TGAATA AAAT GAAATAATT TT T TTAAAAAAAATAGAGAAAAGAT T AT GTGATAATATAAT TACAAAT TAT TACAT TAT CACC GC CAAAACTTATTGTAGCATGTGAGAATGTGATTATTAAAT TAAAAAAAGGCAAAGTTGGAAGTTAAACATGTCATCT TT CT TCCT TT GTAGTC TGCC CTAAGCT TAAC CAT GTT GT CT CCCCTTTTTAAAA-AAATAAATTAAAAGTTGCATTATTGA T TAT TAAGT TTACAAAT TATATCC TAT GATAAATT GCTA AT TGAAC CATACC TAATAAGC CTAAGC TAT TAGATC TAT CACTTATATATATAGTTGCACACATTCGTACCCCTTAGG TCCTTACTAAATCAATTTCGATCTCGGTCATTTAATATT GCTAACAACTATCTGTATAAGAATCTATTAAA-ATGTATA AGCTCGATATTTTTCAA-ATGAAA-ACAAATACTTCGTAAT TCATTTTTGTTCGGTTATCTTTAATTGTCCACAAGGTGG ATAATAATTAGCTT GGTAGTGCAATAATAAACAAGAATA ATACTAGCTAGTGCAATAATAATACAA-ATGTGAAGATTA TCAATAATAAACACAATTAATTGTAATTAACTCAAGATT AGGTGAATTT TAT GAT GAGGAGTGTAGAGTAA-AGAAT GT GGGGACATAACATAAGAT TAT TAAAGTAGATTATCCTAT AACCTT TTCT CCACATCT CTACT TATCTC TTAGTAT TAA AT TAGAAAGAC T TGAAGC TTAAGAAT CAAGGTAATATAC ATGGTATATCTAGCTTGTTTGTTGAAGCAATTTTGTAGG GCACTTCAACTTTATTTTTTTTATTTTTTTTAATTAAAT AGT GACAATATAT TTAAT TTT GAT CATTT TTAT TTAT CT TGTATGCTAGTAA-ATTAAAGAATTAAACCTTGGTGTCAG GAATAAATAAATAAATAATAC TGAC TTTC GATTAACGGA ATAATAGAGAAAGT TACATAGGAGATCGAATTCAATT CA CTTGTTTAA-ATCTTACCTATAGTTTATACCATGTATGTT TTTACTACTTCATAAATAAA-ATTTAGGACATGTTTGGCA _________________ATTGATTTAATACTAACGATTTTTTTTTATTTTTTTTAT 169 WO 2013/039990 PCT/US2012/054789 GACATTTCGTCATCAATTTGAAAAGGTGAATATCCATTA TCCTAGGCAACACACTTTCGAACAGTCTACAAATAAACG CAAATAAATCAAACCAGCGAATTGCGATTGAGTGCATAT GTATGAGATGATGATCAATCATCGCATATTACTCCGAAT AAAGCATTGATTGATTTGGAATGAAAGATATCCAAAGAA TATTGAAGGAAAGATGCTAAATTGCTATGAATATATATA CAATGAAGATTAGCTTGTTTATTATAGTATTCAGGATTA GCTTGTTTATTATAGTATTCAGGATTGGAACCTAACCAC CCAAAACGGATTCTCGAATCCGGATTAGTTCAATAGGTT GAATTGGATGATACACCAAAAAAAAATTATAATATTCAA GAGTTTGAATTAGCATGTGCAAGTAGCGCGATGACACAT AGTCCAAAAATAAAAGGATCTGGTCCAAAATTTACTATA TAACTTATTACATAATTAAAGATAAAATTTGTAACATAC ATATACGGGACATATTTAAAAATTACACCAATCTTTAAA ATCCTTGTAATATCGTAGCCACGACATTGTTTGTATTGT AGTAGCACGTACACCTGCCCAACATAACATCGCTATTCT ATTGAATTGAACACAAAAATGAAAAAAAGGACTTATTTC ACATTCTCACAGCATTCACATAATCACATGTCTTTGTCT CCCGTTCTATTGAATTTAACTCCACTCCTATATTAATTA TTTCCCATACAATAATACAAACAAACAACTTACACATAA AAATGAATAATAAAAGACAGTGAGAGATCAGGGCTGCCT AGTCAATCCAGTGGATTAACAAAAATTGTCAATCTAATG GCATTTTGGTAAATAAA 99 Kochia Genom 5741 ATTTTATTTACAATTTTGCCATTTATTTTTTTCTTTTTT scoparia ic GGTTTTATTTACCAAAATGTCACTAGATTGACAACTTTT ATCAATCCACTGGATTGACTAAGAATTTTTCGTGAGCGA TAGTTCGGTAGATAGAAATTTTCTTTTGATCTCGAGAAA TTTTAGGATCGATTTTCATTTTTGATCCACCCTTGTGAC TCTTTAAAAATATATATTAAAAAAATGTATAATAACGCC CACCTTATTTAGGAAAACAAAGTGGATCTTTTTCTGTTT TATTTTAAACCGTGCCCTGTATCTGTGTGTGTGACCATT ATTTGGCCTCAATTTTGAACTTCTCCGAGTAGTTGTTAA TACTTAGCATTTGGGACCTGCAATGTTTAGGTTTTAGGA TCTGCAATGTCCGGTGGTGGGGAAGCCTCATTGAATGGG GAAAGATGTACTGGTAATGTAGATGGTCCTTACAGTGAC TCTTCACCAAGGAATGATACAAACCCTAAGCCTTCTTGT GATGCTAATGTTCCAACTGTATTAGATGGTCAAGTCGGT GGTGCTTGTGATGATGTAGATGTTAATGAAATTGTTTTG GAAGCAGTACCTCCTGTAGTCGGAATGAGTTTTAAAAGT ATGCTTGAGGTTGATGTGTTTTACAAGAAGTATGCAAAG AGTAAGGGGTTTGCTGTTGTGAGGGTTGGTGGATCGTCT AATGTTGCTAAAGAAAGAATAAATCAGACATGGCGTTGT GAGTGTTATGGCTCTCCTGATGCGAAGATTATTGCCAAG TCAAAGAGATTTGCTAAGGATCCAGTATCGGAGAATTTA AAGGATCAGGAACTGTGTAATCCACGTAGGCGCAAGTCT AAAAAATGTAATTGCACAGCTAAGATTTATGCTAGTGTT AATGAATGTAGACATTGGATTATACGTGAAGTAGTGCTT GATCATTTGAATCATGATCCCAAACCTAAGGATGCCAAA CTAGTGAAGGCATATAGGATGCAGGAGTTTACTTCTACG GACCGTTCAAGAGTTATAAATGGTGCTGCAGCTGGTGGG AAGGTGGGTGTTATGTATGGTTCAATGGCGAACGAAAGG GGTGGTTATGAGAACATGCCCTTTACTCAATGTGACATG AGGCATGTGCTTAATGAAGAACGTAGGAGAAAGATGAGT GGTGGTGATTTTAATGCGTTGCTAGCTTATTTTGGGAAG 170 WO 2013/039990 PCT/US2012/054789 TTGCAGCGTGATAATTCTAACTTTTATCATGTTCACCGA GTCGATTCTGGGGGAACAATCAAGGATGTTCTGTGGGTA GATGCTCGTAGTATGGCCGCATATGAGGAGTTTTCTGAC GTTGTGTGTTTTGACACCACGTACTTGACTAATCAATAT TCTTTACCTTTTGCAAATTTCATTGGCGTTAACCATCAT GGTCAAAGCATCCTTTTTGGGTGTGCTCTGATTTCCAAT GAAGATAGCGAGACGTTTGAGTGGGTTTTTAGGGAGTGG CTGTTATGCATGAAGGGAAAGGCTCCGGGTGGTATCTTA ACCGATCAAGCCGCTGCAATGCGACGACCCTTGGAGAAA GTCATGCCTGATACCAAACATCGTTGGTGTATTTGGCAT ATTACCAAGAAACTGCCCTACAAGTTTGGATCTCGCAAG TGGTATTATTTCGAACCCTAATCTTCCTTGTTTATTCTT GTATTTGTGTTATTTTGCTGTTTAGTGTCTCCTTGATAA GTGTCTTGTGACTCCTTGATTTTTTTCACTTGTGCTGAA TATCTTAGTGAAATGCAATTGTTTAAATCTTAGTGAAAT GCAATTCTTAGTGGAATATCTTAGTGAAATGCAATATCT TAGTGAAATGCAATTCTTAGTGGAATATCTTAGTGAAAT GCAATATCTTAGTGAAATGCAATTCTCTTAACATTCGAT CAAATTGAAATGCAATTTTTTTGCTTGTTCTGGTGTTGT TGAATGATTAATTTTCCGGTTTATGCTTGTGTCGTATCT TTCATAAGTTGCAGCATATTATGGTAATATGTTTTAATT TGTTAATATTTCCAAACTTGCACAGTTACAAGGAATTTA AGAAGGAGTGGTTGAATGTTGTTTATAATAGTTTGAATG AGGCCTCCTTCGAACGCCGTTGGAAGGAGGTTGTGAGTA AGTATGGTTTGGAAAACGATGAGTGGTTGCAGAATCTAT TTGCTGAGAAACACATGTGGGTGCCCTCGTTTATGACTG ATCATTTTTGGGCGGGTATGCGTTCTACGCAAAGGGTGG AGAGTATAAATAGTTTTTTTGACCAATTTGTTGATCGAA ACACGTCCTTTGCTGAATTTGGAGAAAAGTACATTAATG CGGTCGAGAAGAGGATTATGGAGGAGAATGAAGCTGACC ATAAGGAGGTGAAGTTCTTTAGGAATTATTCTACTGGTT TTAGTGTCGAGAGGTTTTTTAAGAAAATTTACACCTCAA GTATGTTTAGGTCTATACAAAAGGAGTGTGAGAAACGAA CCTATTGTATGATTGATGAGGTGAAGAGGTTGGATGACA AAAATTTTGAGTATTTGATGGAGGATAGGGTGTGGATTA AAAAGAAGAAGAGATATATTGAAATATTGACTGATGATC GTACTCACTATACCGTGTCTTACAATTGTGAGACTAAGG ATGGTATTTGTGAATGCAAAAAATTTGAGACTGACGGTA TTATTTGTAGGCACTTGATAACTCTCTTTTATAAGGTCA GGCTAGATGATATACCAGATAAGTACGTTCTTAGGCGTT GGAGGAAAGATGTTGTGAGGAAGCACTCTAGTGTCACTG TCTCCTTTCATGATTTGAGTCGAACAGAACAGGTTAAGA GGCGTGATAGGTTGGTGGTGGTATTTGAGCCTCTTAGTC AACTTGCTTCAAAGTCAGAAGTGTGTACTGTAATTATGC TTAAAGGCATGGCTACAATTGAGGGTGAAATTACTAAAG TGTTGTCTGAGGATAAGGTTGAAGAGGTTAATGAAGCTG CTGCTGATGTTGAGATGCAATCAGGTGTAGGATGTGACA CGGATGACAGCCTTGATGGCTCTGAGTCTGAAATGGGTG GCCATAGCAATGGTGTTGAATCTCGAGCGAGTGAGGTAG TAGGCTCATCTACAAGTACCCCTAGCAAAAGTGTAGGAA TCAAGGATCCAGTTATTAAAAAGAAGCGCGGAAGGCCAG TTGGTTCTAGGTTCAAGGCAATTTCAGAGACGGGTTGGT CAT T GAAAT CAAAAT CT CAAAGT GAAT CAT GCAC CT GT C AGTGCGATGCTCATAAGTGTGTGAGCTCTAAGAAGAAGG 171 WO 2013/039990 PCT/US2012/054789 GACGTGGGAAAGGCAAGTGTAACGAGAAGAAGGTGTCCC AATCTGAGCACACACAGGTATGTTTTTGGTTTCGTGTCT CATTTTAATCAAAGTGTCCCATTTAATTACAATATTAAC TATGCTCTGTATGAGTTCATATTTAATGTAGTGTGTTTG AACTTAGGATGATGGAGCTCAAGCCTGCAGCAATCCCGG AGATGCCCCTCGTAAGGTGACTGGGATATTAGCTATTCA TGTTCAGTGTTTTTCATTATTGGTGATTTGATACTTGAT ATGCATGTTCATTCTTGAGCCGAAGAAGTCTCTTATTGG TGCTTTGATACTTAATATGCATGTAAATTTGTTTTGATT TCAATTGTTTGCAGTCGAAACGAATCAAAAAAGTTTCTT TCGTTGATGAGGAATTGAATCCGGAAGGAGATACTCGTG TAGGTGATGTTTTTAACAATGCCAATGAAAGTCAGGATT ATGTTTCCTTAAGTTGACTCAACATTTAAATGTTAAAGG TATTTTATTTTAAAATTTCCTCTACGGCGGCATAAATTT TATTTACGAGCATTGCATCATTAGTATGGTTGACTAGAA TGTTAGATACAATGAATGCTTTTGCGAAAAATGAAAAGA AATGTTTCTGGGATCATGCTCATGACTTCACCCTTGTTT GACAGGAAATGATGTTTGAATTGAAGATTGTTGGAACGA TTTCAGCTGTGCAATCAGGGTGCTTCAAGTGATCCGCTT CAAAAGATTAATGCTAATTGGAAACTAGTGAAAGACGAT TATGCGTGTTTCCCTTTAATTATGTATTTGATTGATGCA TTCTTTCATTAATTTGCTCACTGTGCAACCAGGAATTCT ATCTTTTGGATTAGAGCTGCAATTTGAAACTTGAAAGAA TTTGTAAACAGGATTCAAAAGTTCTCGCATTGCATATTA CGCTATTCTTTTGTTGAGTTATACTTCATTATCCGTCAC TATTGCCATTATAATACATAGAGATTTTTCTTGAACACA ATAATCATGTGTTTTGTTGCACGATATTACTAATTACTG TTTGATGATTTTTAAACCATTAACTTCATATTGTAACTT TCATTTAATGCTACAGATTTTTATCTAAAATTAAAAAAA GGGCACCCAAAAAGGATTATAAATTCCATGATGATCTAG TTAGCTTGTTGATAAGATAACTTCTCTCCCGTATCCTCT TGAATTTGATCACATTCACATCATATCAAGAAACTAAAA TAGGTAGAATAGATTGGTGTTAGTTGAAAATAGTGCAAA GAAACAAGCTAAGGTTAATAAATAAGACTTATTATACAG GTGACAAGTAATATTATCACTAATTAAGCTAGATTCTAC GTAATAAATAAGACTTATAATAAGACCCTATTAATATTC TTGACGTGGACATTGTACGTAAATAATGGTAGTCGAGTC AAAATGTATAGATAGATT GGAGAGT CAAAATGTAAATAA TGGTAATCGCAATTATTTCACCCATTTTCTTCTTTTTAA TCAGCACCATCCATAACAAACATTCGATTATGCTGTGAA CAAATCAGAT CAT GAAAGTAAGTCAAGGT GAACAAAT CA GATCATGCAAATTACAATTATGCTACAAAGAACTCAAAC TTGTTCCAAAGCTCGAAATCCAAGAAAGTCTCAGGGGTT AAAATAAACAATGC TAGGACAAATT CGAATCCAAAAGTT TGTCTTTCGTTCATTGCACCATATTTAATTAAACATAAA TCCATACAAACATAAGAAATTCCTAAACATCATTCAACA CATAATAGCTAATGCAATTCGCACTCCCTTCCGTATTCT GCTCGGCCAAACTTGGGTTACTCCACTTCCTTCTTTACA CCCTGAAATTCAATTGAAATCAGTTTGCAACTTACATGA GTCGACAACAGGACAATGAAGTTATTAAAATAGGTGACA CAAAGAGGCAGCACACAAGAATCTAGATTAATACCCCAA AATGCATTTTGATAATTAAACAAGAATCTAGTTTGCAAT TTTGTGTTAACAACAAACCAGTGGGCATTTAATTTATGT TTTAAAATATTACTAAACCCTAAACCCTTAACTTTGTTT 172 WO 2013/039990 PCT/US2012/054789 ATATTAAACCATGCACAACCATTAACTTTGTTTATATTA AAAATTATGTTATAAAATATTACTAAACCCTAAACCCTT ATTCGGATATGGTCATACCTCGATGCGACCATGCATCTC CCCCTCTATTAGCTGTGAGCGAGTGAAGTGCACCTTGCC TTCATCCCAAAGCATTAAGAGGCCGCCTGTTTTCCCTCG TGGAGGAGTGTACACCATTTTGTAATGTAGGCCAACTGC TTCAAGGATGTTGTTGGTGTGGAATGGGGAAGTTCTACT CTCAGAGATGAAGAGTACACATGGCGTGTGATGGGTGGC CAAGTGAT 100 Kochia Genom 4546 CCCTCGTTTTCCTCTTCTTTTTTTCCATACAGGTTTTGT scoparia ic AGTCATTTAGTGGAGGTGGGTTGATCTCCTAATAAAGTG GGTTTGTCGATTCTTCTTTCTTCTGCAACCAGCAGAGCC GAGTTGAATTGAGGTGCAGCCTTGAGGAAGACCTGAAAC AAAGTCATTACAAAGAGAATTATAGATGTTCATGATTCT GTGTAAGCCTGATGAGCTTTGTAAAACTTTGTAGTTTGT GCAATTTGGTAATTGATTTTGTAACCACCATCGTTATCT TTAGCGCGCCTTATGGTAAATTTGGAAGCATAATGAGCT AAAAGATCCCAATTTGGCTTTGTAAAATTGCTATTGATT GGAACCTTGTTTTTGGGAGCTTGAAACGATTACTTCAAA CAAACAAAAAAAATTGTTGATGCCGTAATGCGGTATATA GTGTTTGTCCTTAATTAGACATTTGGGGTTTTTTTTCCC AACTTGAATTTGACAAAGATGAGATCCCAGGAATAAGTG ACAGCCAAAACTTAAGTTGGTGCAACAACTAGTGTAATT CATAAATTTTGTATGGTGTGATAGTGTCAAAATTATAAC TAGGGCACACAAAATGACTGCAATAATGCTTAATAAGCA CTAAATGTACTTTGTGTCGAATTTTGAGTCAAGTCCACG TGTCTTTGGATCGGATAAGACAGTCCATGGTTTAGCCAA CGAGTCAGGTTCACGTGTCTTTGGGTCGTATAAGACGAT CCATGGTCTAACCCGGTGACGATGCGCCGTGCCCTAGTT GCCCACTAGTAGGCAAGGAAAGTGGTGTTTGCATGGAGC CTAAGAAGATATGGATTAGGCTGTCACTGATCCCTTGTG GCCTTGTATGTTAATCAAATTATTAGTAGAGGTTATAAA GGGGGGGTTGGTGAGCTACTAAACTGATTGCCTTGTTGA TTGACAAAACCATTTTATGATTTTAGTTCCATCTTTATT CAATAGTTTATATATGGTGTGCTACACTAGTATTATTAC TATTATATGATGGAATATTATTCTCTCCTTTTCTTTCAC ACATATTCTTTTTATCTACTACATTAATTTATATAATAC CACATGAAGTATATACAAAGTTGCTTATTTCTTATGTAA TAAGCACATGATCATTGTGATATTAATTAATCTTTTCGT GGAGAAAATGACTAGAGGAAAATTCAAAATATTAAAGTG TTTTTATGAACAAATGAACAAATGGTGTTAATCTAATTT CATAGACAAGTTGGTAACTATGGTCAATCACCTCGGGAA AAAGTAATGACAATTGTATCGATAGTTTGGTTCATGTGG AATCAAAAAAATTTATCGAATTCATATTATTAATTTTGT GTGCGAATGAATATCTATATTTCATGGAATATTGACTAA ATTGTGTGATTTAGACTAAATAAAAATGCATTAACGAGA GTCGATGAAATCGTTAAAGGATTAAAACATTAATAAAAT GATTTATATTTTAACTTTTTCATAGTTAACCTAAAATAG ACAAAAAATTACTCATACTCGATATAAAAAAGGATTTTT TTATATATAAATAAACATAGAGATATATAATTTTAAAAA AAAATAGCTCGAACTTATTCTCCCATTTGTTTTATCCTT TATTGATGTAAATCACTAACAAAGTTAATTATCATTCCA TTCTTAATTTTTTTTAATGAAGGTCAATATTCTTACAAT AGTGATTAGCTTTTTCAATATAATTTTGTTCCAAAAAAA 173 WO 2013/039990 PCT/US2012/054789 ATATTAGTGATCTTTCTTTTTAAAAAAAATGGTAGCACT AGCACACCAACACTCTCACAAATTCAACCACAACAACCC ATGTTTTTGATTTGCCCAATTTCTTCTTCACCAACCCCC TTCTCTCTTCCACCTAATTTTGGTTGGTGAATCCTTCTT CTCATTCTCTCTCCTAAAAAGAAGCTTAAACCCATCGTC AAT CAT ATAG TAT TAGC CAT CAAAAACAACAACAAGAGA GAGAAGAAACAATGGCTCAAGCTAC CACC TTTAACAATG GTGTCAAAAATGGTCATCAATTATGCGCCAATTTACCAA AAACCCACTTGCCCAAATCTCAAAAAGCTGTCAAATTTG GATCAAACTTGAGATTTTCTCCAAAGTTGAAGTCTTTCA ACAATGAAAGAGTTTCTGGGAAATCATCAGTTGTTTTTA AGGTTCATGCTTCAGTTGCTGCTGCTCCCTCAACTTCCC CAGAAATTGTGTTGCAACCCATTAAGGAGATTTCTGGCA CTGTTCAATTGCCTGGTTCTAAGTCTTTATCTAATCGAA TTCTTCTTTTAGCTGCTCTTTCTGAGGTACTTTTCGATT GTTTGATTTCATCTTTTACCCTGAATTTGGCGTTTGTTT AATGCAGTTTTTGTGTTTTGAATCTTTGTAATTTATGTT AAGTTTTAAAAGAATGATGCTTCTTGTTTCTCTTGTTGT TTGTGCATTGGTTGTTGGATTGGTATCATTGAGAAATAT GTATGCATTAGTAAAAATTGGTGTGTTTTGTGTAGTTTT GCATTAAGTTGTTTAATTGATATCATTGAGAAATTGGGT TCAGTACATTGTTTGACTTTGGAATATAAAAATTGGTGG AAAAAAAACAGCAGATTTTTAACAAATGATTGTTATGTG AAGATTTGTTATCATATAATGGAGGATGAAAGTCCTGAA GTTGTATGAACTAGATGATAAAACCTCACTTTCACTGAT TTCGGGGTGGACAATCAAAGAACCTTGATCGAGTAGGAG CAAAATGACACCCTGAACATAGATGAACAGGCTTCATAA TATATGTATTCACTTGATGCTTTCGGTTACCTCGAACTG CTGATGAGGTTGAGGAAATTGGGATGTGTGGTGCACTTT TTCATTTTGGTGGCAAGAATGCAAGCCTTATGGTACGGC TTGGGAGCGATCACTGATTAGTTGGCTCAAGCTTGACTT TTCTAGGGAGACTATCTCGAGGAAGGTGGTTTAGTTTAA TACGGTGTACAGTAGTCGAATCCTCACAAATCACAACTC AAATCCAAGTAAAAGGGACAACTACACATGAAACTCAGA TTAGTTCATTTATCAATACCTCAAGAACATACTTAAGGA ACCAAGTACAATTTCTTCTCTAGATATTGAAAGGGGAGG AAGTGATATAAAAACCTAAACTCTTGTCAGGCCACACTT AAAGGTCCACATCATATACCCCAGAACTATAGGTTAAAG ACATACAGTACATAAGAATTACGTCGATATGTTGAAAGA ACTGTCAGATTCTAACATAATTGCACACAAGCATTCCTC TACAATCTGAGTTTAACGAAATTCCCATCGCCTGCTTGC AACAATGGGCATCGTAAGTCCATTCACTAGCACCTTCAT CTTCACCTTCACCTTCACTTGACCCAGATGGCACATTGT AGTGCAATTTGAAAAACTATTCTGAGAACTTACATAACC AGCCTTTGTTCATAGTTACAGTCCTTCGAATCCTACTCC TTAGGCATGCACAATTTCTTCCTATCAATAAGGAGCTTT TAGGTTCTCAAAACTGAGGTGGGAAGGAAAGTTGAGAAT AGTATGCATTTAAGTTTGTTTTTTCATTTTTCGTTCCTG AACAACTACACATGTCTCCTGTAGATGGACTTTGGTACT AGTGTAATTCTGTGTCAGTCTCATGTCTGCTGCGTTTTT GCACCCTCCCTTTTTCTTTGACCTTGTGTTGTCCTATTT TCTAAAGTTTCAACAACCTAACCAAATTTATGCTGCAGG GTACAACAGTACTTGACAACTTGCTATATAGTGATGATA TTCGCTATATGTTGGATGCTCTAAGAACTCTTGGGCTCA 174 WO 2013/039990 PCT/US2012/054789 ACGTAGAGGATGATAATAAGGCCAAAAGGGCAATCGTGG AGGGTTGTGGCGGTCTATTTCCTGCTGGTAAAGAGAATA GGAGTGAGATTGAACTTTTCCTTGGAAACGCGGGAACGG CAATGCGCCCATTGACAGCTGCAGTTGCCGTTGCTGGAG GAAATTCCAGGTTAGTGAATAACGATTTCTATGTGGATG TAATACTGATAGGTTTGTGTAAGGCTTATGATATAGTTG CACGATAGGTCTACTAGAAAGATGCTATTCATTGTGAAA AAATATGTTAGATTAATGTTTGTGAAATGAAAATTTAAA GAGATTGTAACTGTGGAAGTATTGCTGATGGATGAACAC AAACTAGATATAATTAAAAGGCTAACAGCGTGTATTATC TCGTTAATATCTGATGAACTTTTTCAGATTTATCTAAAC ATAAGCTATTGTATTGGGATTAGGATAATTCTCGTAGTC CAGACATCCTGTCATGGAGTAAGGATTCTTAAGACTATG GATGGTTAATTCAAACTCTGGCAATCATCTTTTGGTAGT GAGAAAACTGCTGTCTTTTTTAGAATCTTCTTTATCCAT AAACTCTTAAATCCTAAATAAACCGGAAGCAATCTTGGT CGTTGATTTTTGAGATGTATGGTCAAGATGTGCATAAGT TTAATAGTAAATGTGCATATTT 101 Kochia Genom 57 GTTTTTGCACATTCACAGGAAAATTCGTGCACATTTACG scoparia ic TACAAAAATTTGCACATT 102 Kochia cDNAC 1548 ATGGCTCAAGCTACCACCTTTAACAATGGTGTCAAAAAT scoparia ontig GGTCATCAATTATGCGCCAATTTACCAAAAACCCACTTG CCCAAATCTCAAAAAGCTGTCAAATTTGGATCAAACTTG AGATTTTCTCCAAAGTTGAAGTCTTTCAACAATGAAAGA GTTTCTGGGAAATCATCAGTTGTTTTTAAGGTTCATGCT TCAGTTGCTGCTGCTCCCTCAACTTCCCCAGAAATTGTG TTGCAACCCATTAAGGAGATTTCTGGCACTGTTCAATTG CCTGGTTCTAAGTCTTTATCTAATCGAATTCTTCTTTTA GCTGCTCTTTCTGAGGGTACAACAGTACTTGACAACTTG CTATATAGTGATGATATTCGCTATATGTTGGATGCTCTA AGAACTCTTGGGCTCAACGTAGAGGATGATAATAAGGCC AAAAGGGCAATCGTGGAGGGTTGTGGCGGTCTATTTCCT GCTGGTAAAGAGAATAGGAGTGAGATTGAACTTTTCCTT GGAAACGCGGGAACGGCAATGCGCCCATTGACAGCTGCA GTTGCCGTTGCTGGAGGAAATTCCAGTTATGTACTTGAT GGAGTGCCAAGAATGAGGGAGCGACCCATTGGGGATCTG GTAGCTGGTCTGAAGCAACTGGGTGCAGATGTTGACTGT TTTCTTGGCACAAATTGTCCTCCTGTAAGAGTAAATGCT AAAGGAGGTCTTCCAGGGGGCAAGGTCAAGCTCTCAGGA TCAGTTAGTAGCCAATATCTTACTGCGCTACTCATGGCT ACCCCTTTGGCTCTTGGAGATGTGGAGGTTGAAATCATT GATAAATTGATTTCTGTCCCTTACGTAGAGATGACAATA AAGTTAATGGAACGGTTTGGAGTGTCAATAGAGCATACT GCTAGCTGGGACAGGTTTTTGATCCGAGGTGGTCAGAAG TACAAATCTCCTGGAAATGCATTTGTTGAGGGTGATGCT TCAAGTGCCAGTTACTTCTTAGCAGGGGCCGCGATCACT GGTGGGACTGTGACTGTTGAGGGTTGTGGAACAAGCAGT TTGCAGGGTGATGTTAAATTCGCGGAGGTTCTTGAGAAG ATGGGTTGCAAAGTTACATGGACAGAGACCAGTGTCACT GTAACTGGACCGCCCAGGGACTCATCTGGAAGAAAACAT TTGCGTGCCATCGATGTTAACATGAACAAAATGCCAGAT GTTGCGATGACTCTTGCTGTTGTTGCCCTATATGCAGAT GGGCCCACAGCTATCAGAGACGTTGCTAGCTGGAGAGTG AAGGAAACAGAAAGGATGATTGCCATCTGTACAGAACTC 175 WO 2013/039990 PCT/US2012/054789 AGAAAGCTTGGAGCAACAGTTGAGGAAGGACCTGATTAC TGTGTGATCACTCCACCAGAAAAACTAAACGTAACCGCC ATCGACACATATGATGATCATCGAATGGCCATGGCATTC TCTCTTGCTGCCTGTGCTGATGTTCCTGTCACTATTAAG GACCCAGGCTGCACCCGCAAGACCTTCCCAGACTACTTT GACGTCTTGGAACGGTTTGCCAAGCAT 103 Kochia Genom 5426 GGGGTATTTCATGGAAAACGCAAATTTACAGGGGTACCC scoparia ic TGTAGAAAATCCCAACAAAAAAAATTGTTGATGCCGTAA TGCGGTATATAGTGTTTGTCCTTAATTAGACATTTGGGG TTTTTTTTCCCAACTTGAATTTGACAAAGATGAGATCCC AGGAATAAGTGACAGCCAAAACTTAAGTTGGTGCAACAA CTAGTGTAATTCATAAATTTTGTATGGTGTGATAGTGTC AAAATTATAACTAGGGCACACAAAATGACTGCAATAATG CTTAATAAGCACTAAATGTACTTTGTGTCGAATTTTGAG TCTAGTTTACGTGTCTTTGGATCGGATAAGACAGTCCAT GGTTTAGCCCATGAGTCAGGTTCACGTGTCTTTGGATCG TATAAGACGATCCATGGTCTAACCCGGTGACGATGCGCC GTGCCCTAGTTGCCCACTAGTAGGCAAGGAAAGTGGTGT TTGCATGGAGCCTAAGAAGATATGGATTAGGCTGTCACT GATTCCTTGTGGCCTTGTATGTTGATCAAATTATTAGCA GAGGTTATAAAGGGGGGTTGGTGAGCTACTAAACTGATT GCCTTGTTGATTGACAAAACCATTTTATGATTTTAGTTC CATCTTTATTCAATAGTTTATATATGGTGTGCTACACTA GTATTATATGATGGAATATTATTCTCTCCTTTTCTTTCA CAAATATTCTTTTTATCTACTACATTAATTTATATAATA CCACATGAAGTATATAAAAAGTTGCTTTTTCTTATGTAA TAAGCACATGATCATTGTGATTTTAATTAATCTTTTCGT GGAGAAAATGACTAGAGGAAAATTCAAAATATTAAAGTG TTTTTATGAACAAATGAACAAATGGTGTTAATCTAATTT CATAGACAAGTTGGTAACTATGGTCAATCACCTCGGAAA AAGTAATGACAATTGTATCGATAGTTTGGTTCATGTGGA ATCAAAAAAATTTATCGAATTCATATTATTAATTTTGTG TGCGAATGAATATCTATATTTCATGGAATATTGACTAAA TTGTGTGATTTAGACTAAATAAAAATGCATTAACGAGAG TCGATGAAATCGTTAAAGGATTAAAACATTAATAAAATG ATTTATATTTTAACTTTTTCATAGTTAACCTAAAATAGA CAAAAAATTACTCATACTCGATATAAAAAAGGATTTTTT TATATATAAATAAACATAGAGATATATAATTTTAAAAAA AAATAGCTCGAACTTATTCTCCCATTTGTTTTATCCTTT ATTGATGTAAATCACTAACAAAGTTAATTATTCCATTCC TAATTTTTTTTTATGAAGGTCAATATTCTTACAATAGTG ATTAGCTTTTTCAATATAATTTTTTTCCAAAAAAATATT AGTGATCTTTCTTTTTTTAAAAATGGTAGCACTAGCACA CCAACACTCTCACAAATTCAACCACAACAACCCATGTTT TTGATTTGCCCAATTTCTTCTTCACCAACCCCCTTCTCT CTTCCACCTAATTTTGGTTGGTGAATCCTTCTTCTCATT CTCTCTCCTAAAAAGAAGCTTAAACCCATCGTCAATCAT ATAGTATTAGCCATCAAAAACAACAAGAGAGAGAAGAAA CAATGGCTCAAGCTACCACCTTTAACAATGGTGTCAAAA ATGGTCATCAATTATGCGCCAATTTACCAAAAACCCACT TGCCCAAATCTCAAAAAGCTGTCAAATTTGGATCAAACT TGAGATTTTCTCCAAAGTTGAAGTCTTTCAACAATGAAA GAGTTTCTGGGAAATCATCAGTTGTTTTTAAGGTTCATG CTTCAGTTGCTGCTGCTCCCTCAACTTCCCCAGAAATTG 176 WO 2013/039990 PCT/US2012/054789 TGTTGCAACCCATTAAGGAGATTTCTGGCACTGTTCAAT TGCCTGGTTCTAAGTCTTTATCTAATCGAATTCTTCTTT TAGCTGCTCTTTCTGAGGTACTTTTCGATTGTTTGATTT CATCTTTTACCCTGAATTTGGCGTTTGTTTAATGCAGTT TTTGTGTTTTGAATCTTTGTAATTTATGTTAAGTTTTAA AAGATTGATGCTTCTTGTTTCTCTTGTTGTTTGTGCATT GGTTGTTGGATTGGTATCATTGAGAAATATGTATGCATT AGTAAAAATTGGTGTGTTTTGTGTAGTTTTGCATTAAGT TGTTTAATTGATATCATTGAGAAATTGGGTTCAGTACAT TGTTTGACTTTGGAATATAAAAATTGGTGGAAAAAAAAC AGCAGATTTTTAACAAATGATTGTTATGTGAAGATTTGT TATCATATAATGGAGGATGAAAGTCCTGAAGTTGTATGA ACTAGATGATAAAACCTCACTTTCACTGATTTCGGGGTG GACAATCAAAGAACCTTGATCGAGTAGGAGCAAAATGAC ACCCTGAACATAGATGAACAGGCTTCATAATATATGTAT TCACTTGATGCTTTCGGTTACCTCGAACTGCTGATGAGG TTGAGGAAATTGGGATGTGTGGTGCACTTTTTCATTTTG GTGGCAAGAATGCAAGCCTTATGGTACGGCTTGGGAGCG ATCACTGATTAGTTGGCTCAAGCTTGACTTTTCTAGGGA GACTATCTCGAGGAAGGTGGTTTAGTTTAATACGGTGTA CAGTAGTCGAATCCTCACAAATCACAACTCAAATCCAAG TAAAAGGGACAACTACACATGAAACTCAGATTAGTTCAT TTATCAATACCTCAAGAACATACTTAAGGAACCAAGTAC AATTTCTTCTCTAGATATTGAAAGGGGAGGAAGTGATAT AAAAACCTAAACTCTTGTCAGGCCACACTTAAAGGTCCA CATCATATACCCCAGAACTATAGGTTAAAGACATACAGT ACATAAGAATTACGTCGATATGTTGAAAGAACTGTCAGA TTCTAACATAATTGCACACAAGCATTCCTCTACAATCTG AGTTTAACGAAATTCCCATCGCCTGCTTGCAACAATGGG CATCGTAAGTCCATTCACTAGCACCTTCATCTTCACCTT CACCTTCACTTGACCCAGATGGCACATTGTAGTGCAATT TGAAAAACTATTCTGAGAACTTACATAACCAGCCTTTGT TCATAGTTACAGTCCTTCGAATCCTACTCCTTAGGCATG CACAATTTCTTCCTATCAATAAGGAGCTTTTAGGTTCTC AAAACT GAGGTGGGAAGGAAAGTTGAGAATAGTATGCAT TTAAGTTTGTTTTTTCATTTTTCGTTCCTGAACAACTAC ACATGTCTCCTGTAGATGGACTTTGGTACTAGTGTAATT CTGTGTCAGTCTCATGTCTGCTGCGTTTTTGCACCCTCC CTTTTTCTTTGACCTTGTGTTGTCCTATTTTCTAAAGTT TCAACAACCTAACCAAATTTATGCTGCAGGGTACAACAG TACTTGACAACTTGCTATATAGTGATGATATTCGCTATA TGTTGGATGCTCTAAGAACTCTTGGGCTCAACGTAGAGG ATGATAATAAGGCCAAAAGGGCAATCGTGGAGGGTTGTG GCGGTCTATTTCCTGCTGGTAAAGAGAATAGGAGTGAGA TTGAACTTTTCCTTGGAAACGCGGGAACGGCAATGCGCC CATTGACAGCTGCAGTTGCCGTTGCTGGAGGAAATTCCA GGTTAGTGAATAACGATTTCTATGTGGATGTAATACTGA TAGGTTTGTGTAAGGCTTATGATATAGTTGCACGATAGG TCTACTAGAAAGATGCTATTCATTGTGAAAAAATATGTT AGATTAATGTTTGTGAAATGAAAATTTAAAGAGATTGTA ACTGTGGAAGTATTGCTGATGGATGAACACAAACTAGAT ATAATTAAAAGGCTAACAGCGTGTATTAT CTCGTTAATA TCTGATGAACTTTTTCAGATTTATCTAAACATAAGCTAT TGTATTGGGATTAGGATAATTCTCGTAGTCCAGACATCC 177 WO 2013/039990 PCT/US2012/054789 TGTCATGGAGTAAGGATTCTTAAGACTATGGATGGTTAA TTCAAACTCTGGCAATCATCTTTTGGTAGTGAGAAAACT GCTGTCTTTTTTAGAATCTTCTTTATCCATAAACTCTTA AATCCTAAATAAACCGGAAGCAATCTTGGTCGTTGATTT TTGAGATGTATGGTCAAGATGTGCATAAGTTTAATAGTA AATGTGCATATTTTTTTGGTTTTTGCACATTCACAGGAA AATTCGTGCACATTTACGTACAAAAATTTGCACATTTAC TTTTTTCATGAAATAAATCTTGATCCTTCATTCAAAATC CAACGATCAAAATTGCTTCTCACGTTTCTCATTTTAAGG GTGCTTCTCATTTGATCCTAAATCTATATACATATGTAA GTACCTTGAATGCCATGGAATTGAAATTTTAAATTATGT GTTGGTTGTGAATGGGGTTAATGAAGTAGATAGAGTAGG CTGACAAATATTCCAAGGGGTACCTACAGCTACTCTTGG TCACTAAGTCATTGTTCTGTTTTTAGATTTTAATTGCTT TCCCTTATGGTTTTTTCAGTTATGTACTTGATGGAGTGC CAAGAATGAGGGAGCGACCCATTGGGGATCTGGTAGCTG GTCTGAAGCAACTGGGTGCAGATGTTGACTGTTTTCTTG GCACAAATTGTCCTCCTGTAAGAGTAAATGCTAAAGGAG GTCTTCCAGGGGGCAAGGTAGAGTAAATTTCTTGTAGAT TAACTTTGTTGATAATTCACTCATTAATATATCAATGAG ACATCCTCAAAAAATAACTCTGTCCTGTTTTCCTGTCAT TAAGCTCTGTTACATAACTTACATTATTTTAAAGCATTT TGATGGAATGTATCTGCAGGTCAAGCTCTCAGGATCAGT TAGTAGCCAATATCTTACTGCGCTACTCATGGCTACCCC TTTGGCTCTTGGAGATGTGGAGGTTGAAATCATTGATAA ATTGATTTCTGTCCCTTACGTAGAGATGACAATAAAGTT AATGGAACGGTTTGGAGTGTCAATAGAGCATACTGCTAG CTGGGACAGGTTTTTGATCCGAGGTGGTCAGAAGTACAA GTAAGTCACTCTTCTTTTACTTGCATGTATTGAACGTCA TTCCATTGGTAGACTGATGCAGCATTAATAATATGTCAG ATCTCCTGGAAATGCATTTGTTGAGGGTGATGCTTCAAG TGCCAGTTACTTCTTAGCAGGGGCCGCGATCACTGGTGG GACTGTGACTGTTGAGGGTTGTGGAACAAGCAGTTTGCA GGTATGATCCAAAGCCTCACTTCAATAAATTTTCAAGTA CACATTCGTTTTACTTCCTCCGTTTTGTATTACTCGCAC CGGTTTCCATTTTGGGAAATTTGCGAATACTTGCACCAC TTTGCTTTATTCCCTTTTTTGGCAATTTATTTTGTTTGA AATGA 104 Kochia Genom 2430 CACTACCCTTCCCTCAACTAATTATACCAACAAAAAAAC scoparia ic GCCTTGGAGTCCGCAATAATGAAAGTGGTGCGAGTAATA TAAAACGGAGGAAGTATTTATTTTTTAGATTAACTGTTG TAACCATTTTTTGGTTAATTTTGAGGCTAAAGTATGGCC TTTTGACAATTAACTTTCAATATTAATCTCTAATGTGGT GTAAAGTCATCCATTTTAATATCAGACAATTGTGTTTGA CTCCCAAAAAAGGATAATTTACTTCTTATTGTTTTGTGA CTGCCAAAAAGGATCACTTGAATGTCATGGATTGTTTAA TCACCTATTTAGGCATTGTTGTGTTGTGATTCACCTCAT CTTTAGGTCCAATAGATTTTGGCTGAATCTTACTTGTGA CTGCCAAAAAGGATCACTGACAATTTACTTGTTTAACGG ATTTTACTCAGGGTGATGTTAAATTCGCGGAGGTTCTTG AGAAGATGGGTTGCAAAGTTACATGGACAGAGACCAGTG TCACTGTAACTGGACCGCCCAGGGACTCATCTGGAAGAA AACATTTGCGTGCCATCGATGTTAACATGAACAAAATGC CAGATGTTGCGATGACTCTTGCTGTTGTTGCCCTATATG 178 WO 2013/039990 PCT/US2012/054789 CAGATGGGCCCACAGCTATCAGAGACGGTATTAACTCCT TTCTGATACATTACACTTTTCTTGTGCTATATATTGTTT CAAATTTGATAATTCGATCATGCTTCAAATTTTGCACAC AGCCGTAATCCATGGTTATAAAATGACTATGACACTTGT CTTGTTACTGAAAAGTGCATACAGTAACAAAGCTGATGT TACTTCTTAGTTTACTCTAATAATGGTTGGACGGTCACT GGCGCACATCCCCATGGTTGGAAGTTGTGAATATTGTTG TCATAATGGCTTATGGAGCATCTTTTGGTACACTTCAGG AGTAAAAGACCACTAGTCCAGTATAGGGTTAATCACCTC TAGAACTAGTTAGTCACATATACTCGGAAAATTATTCAT ATTTTGTGGTTACATGCGTTCGTTTATCTGCATCTTGCC TAGTGTCTCCTCTTGAAATCATTCATATATGTTCTTTTT TTTCCCCTTCATCTGTTACATGTTCAAAATATGCTTACA ACGAAATTGGGTAACTTGACCAGTTGCTAGCTGGAGAGT GAAGGAAACAGAAAGGATGATTGCCATCTGTACAGAACT CAGAAAGGTTAGCCACATTCTTTAATCTTGTAGTAAAAA ATAAAGTTGCCTGTTTCATGTAAGTTGATGTTAATTCGG ACTTTTAAAATTTTCAGCTTGGAGCAACAGTTGAGGAAG GACCTGATTACTGTGTGATCACTCCACCAGAAAAACTAA ACGTAACCGCCATCGACACATATGATGATCATCGAATGG CCATGGCATTCTCTCTTGCTGCCTGTGCTGATGTTCCTG TCACTATTAAGGACCCAGGCTGCACCCGCAAGACCTTCC CAGACTACTTTGACGTCTTGGAACGGTTTGCCAAGCATT GAGCGGCTATCTGCAGATTTTTCATAAAGTATGCACGAA AGTTTCAATTTAAGAAGATACCGAGTTGATTATATGCTT TCCGCATAAGTTATTGTCACATTTTTTGTATTATGTTTG TAAGATCTTAGGCAATAAGATATACTGTTAGAAATTATG TGTATCTGATTATTTAGAGATGTATACTTGGGTCAGTTG AAATTGTACGAGAAAGGTCTGGATTTCGAAAAAAATGTG ATCCAGACATTAGTGTGGTCTGAACTGAAGCAAGTACTC CCTCCGTCTCATAATTCTCACAACTCTTGCTATTATTTG TGAGAAATAAAATATTCAAGTGTTGCGAGAATTGTGTGA CAGCGGGAGTAGCAACTTTTCAAGTTTGGAATTAATTTT GTGATGTGAGTTTTTTGTGTATTCTTTGTTTTCCATCAA ACCCTCCTCCAAAGTACAAACCCAATTCATGGTATGGTT GATGCAACAGCAATATGTCAAAATCAGTGTTTGTGATGT TGGCTTCTCTACTTCATTATCTCTTCTTGTTCAGTATGA TTTCGCAATCTCTTCCCGTCAAAATCCCTTCTCCTCTGA TAATCGCAGAAATCGTGTCTTCCCCTCGGTGTGTATCCA CCTCTTAAAAATTTGTTGAGAGTTGAAATGTGCTGCCAC TGGATTCATCCTTTAGGGCGAATTTTGAACGGATTTTAG GTGGTTAGGATTCAACCCCTGTCAATTATAGTTACGGGA ATTAGACACGCGTTCTGCCTTACCAACCCCATTTTTTTG TCACTATATCAAGTATCCATTGCTAGTTGTAGTCATGTA GTAGGGTCTGAAATCTAAAGCAAAGTAGCAAGATTGCAA CAACAGGAACAGCAAATAAATCTAGACTTTTGAGGTTTG TTTTTTTTTTTT 105 Kochia Genom 4880 TCACCTTCACTTGACCCAGATGGCACATTGTAGTGCAAT scoparia ic TTGAAAAACTATTCTGAGAACTTACATAACCAGCCTTTG TTCATAGTTACAGTCCTTCGAATCCTACTCCTTAGGCAT GCACAATTTCTTCCTATCAATAAGGAGCTTTTAGGTTCT CAAAACTGAGGTGGGAAGGAAAGTTGAGAATAGTATGCA TTTAAGTTTGTTTTTTCATTTTTCGTTCCCTGAACAACT ACACATGTCTCCTGTAGATGGACTTTGGTACTAGTGTAA 179 WO 2013/039990 PCT/US2012/054789 TTCTGTGTCAGTCTCATGTCTGCTGCGTTTTTGCACCCT CCCTTTTTCTTTGACCTTGTGTTGTCCTATTTTCTAAAG TTTCAACAACCTAACCAAATTTATGCTGCAGGGTACAAC AGTACTTGACAACTTGCTATATAGTGATGATATTCGCTA TATGTTGGATGCTCTAAGAACTCTTGGGCTCAACGTAGA GGATGATAATAAGGCCAAAAGGGCAATCGTGGAGGGTTG TGGCGGTCTATTTCCTGCTGGTAAAGAGAATAGGAGTGA GATTGAACTTTTCCTTGGAAACGCGGGAACGGCAATGCG CCCATTGACAGCTGCAGTTGCCGTTGCTGGAGGAAATTC CAGGTTAGTGAATAACGATTTCTATGTGGATGTAATACT GATAGGTTTGTGTAAGGCTTATGATATAGTTGCACGATA GGTCTACTAGAAAGATGCTATTCATTGTGAAAAATATGT TAGATTAATGTTTGTGAAATGAAAATTTAAAGAGATT GT AACTGTGGAAGTATTGCTGATGGATGAACACAAACTAGA TATAATTAAAAGGCTAACAGCGTGTATTATCTCGTTAAT ATCTGATGAACTTTTTCAGATTTATCTAAACATAAGCTA TTGTATTGGGATTAGGATAATTCTCGTAGTCCAGACATC CTGTCATGGAGTAAGGATTCTTAAGACTATGGATGGTTA ATTCAAACTCTGGCAATCATCTTTTGGTAGTGAGAAAAC TGCTGTCTTTTTTAGAATCTTCTTTATCCATAAACTCTT AAATCCTAAATAAACCGGAAGCAATCTTGGTCGTTGATT TTTGAGATGTATGGTCAAGATGTGCATAAGTTTAATAGT AAATGTGCATATTTTTTTGGTTTTTGCACATTCACAGGA AAATTCGTGCACATTTACGTACAAAAATTTGCACATTTA CTTTTTTCATGAAATAAATCTTGATCCTTCATTCAAAAT CCAACGATCAAAATTGCTTCTCACGTTTCTCATTTTAAG GGTGCTTCTCATTTGATCCTAAATCTATATACATATGTA AGTACCTTGAATGCCATGGAATTGAAATTTTAAATTATG TGTTGGTTGTGAATGGGGTTAATGAAGTAGATAGAGTAG GCTGACAAATATTCCAAGGGGTACCTACAGCTACTCTTG GTCACTAAGTCATTGTTCTGTTTTTAGATTTTAATTGCT TTCCCTTATGGTTTTTTCAGTTATGTACTTGATGGAGTG CCAAGAATGAGGGAGCGACCCATTGGGGATCTGGTAGCT GGTCTGAAGCAACTGGGTGCAGATGTTGACTGTTTTCTT GGCACAAATTGTCCTCCTGTAAGAGTAAATGCTAAAGGA GGTCTTCCAGGGGGCAAGGTAGAGTAAATTTCTTGTAGA TTAACTTTGTTGATAATTCACTCATTAATATATCAATGA GACATCCTCAAAAAATAACTCTGTCCTGTTTTCCTGTCA TTAAGCTCTGTTACATAACTTACATTATTTTAAAGCATT TTGATGGAATGTATCTGCAGGTCAAGCTCTCAGGATCAG TTAGTAGCCAATATCTTACTGCGCTACTCATGGCTACCC CTTTGGCTCTTGGAGATGTGGAGGTTGAAATCATTGATA AATTGATTTCTGTCCCTTACGTAGAGATGACAATAAAGT TAATGGAACGGTTTGGAGTGTCAATAGAGCATACTGCTA GCTGGGACAGGTTTTTGATCCGAGGTGGTCAGAAGTACA AGTAAGTCACTCTTCTTTTACTTGCATGTATTGAACGTC ATTCCATTGGTAGACTGATGCAGCATTAATAATATGTCA GATCTCCTGGAAATGCATTTGTTGAGGGTGATGCTTCAA GTGCCAGTTACTTCTTAGCAGGGGCCGCGATCACTGGTG GGACTGTGACTGTTGAGGGTTGTGGAACAAGCAGTTTGC AGGTATGATCCAAAGCCTCACTTCAATAAATTTTCAAGT ACACATTCGTTTTACTTCCTCCGTTTTGTATTACTCGCA CCGGTTTCCATTTTGGGAAATTTGCGAATACTTGCACCA CTTTGCTTTATTCCCTTTTTTGGCAATTTATTTTGTTTG 180 WO 2013/039990 PCT/US2012/054789 AAATGACCATTTTAGCCTTATTGTTTTTCCCCACATGGT GGGATCAAAGGAATTAACACCATAAAACACACCTCCTTT ATACCCCACCAACTTAATCACACTACCCTTCCCTCAACT AATTATACCAACAAAAAAACGCCTTGGAGTCCGCAATAA TGAAAGTGGTGCGAGTAATATAAAACGGAGGAAGTATTT ATTTTTTAGATTAACTGTTGTAACCATTTTTTGGTTAAT TTTGAGGCTAAAGTATGGCCTTTTGACAATTAACTTTCA ATATTAATCTCTAATGTGGTGTAAAGTCATCCATTTTAA TATCAGACAATTGTGTTTGACTCCCAAAAAAGGATAATT TACTTCTTATTGTTTTGTGACTGCCAAAAAGGATCACTT GAATGTCATGGATTGTTTAATCACCTATTTAGGCATTGT TGTGTTGTGATTCACCTCATCTTTAGGTCCAATAGATTT TGGCTGAATCTTACTTGTGACTGCCAAAAAGGATCACTG ACAATTTACTTGTTTAACGGATTTTACTCAGGGTGATGT TAAATTCGCGGAGGTTCTTGAGAAGATGGGTTGCAAAGT TACATGGACAGAGACCAGTGTCACTGTAACTGGACCGCC CAGGGACTCATCTGGAAGAAAACATTTGCGTGCCATCGA TGTTAACATGAACAAAATGCCAGATGTTGCGATGACTCT TGCTGTTGTTGCCCTATATGCAGATGGGCCCACAGCTAT CAGAGACGGTATTAACTCCTTTCTGATACATTACACTTT TCTTGTGCTATATATTGTTTCAAATTTGATAATTCGATC ATGCTTCAAATTTTGCACACAGCCGTAATCCATGGTTAT AAAATGACTATGACACTTGTCTTGTTACTGAAAAGTGCA TACAGTAACAAAGCTGATGTTACTTCTTAGTTTACTCTA ATAATGGTTGGACGGTCACTGGCGCACATCCCCATGGTT GGAAGTTGTGAATATTGTTGTCATAATGGCTTATGGAGC ATCTTTTGGTACACTTCAGGAGTAAAAGACCACTAGTCC AGTATAGGGTTAATCACCTCTAGAACTAGTTAGTCACAT ATACTCGGAAAATTATTCATATTTTGTGGTTACATGCGT TCGTTTATCTGCATCTTGCCTAGTGTCTCCTCTTGAAAT CATTCATATATGTTCTTTTTTTCCCCTTCATCTGTTACA TGTTCAAAATATGCTTACAACGAAATTGGGTAACTTGAC CAGTTGCTAGCTGGAGAGTGAAGGAAACAGAAAGGATGA TTGCCATCTGTACAGAACTCAGAAAGGTTAGCCACATTC TTTAATCTTGTAGTAAAAAATAAAGTTGCCTGTTTCATG TAAGTTGATGTTAATTCGGACTTTTAAAATTTTCAGCTT GGAGCAACAGTTGAGGAAGGACCTGATTACTGTGTGATC ACTCCACCAGAAAAACTAAACGTAACCGCCATCGACACA TATGATGATCATCGAATGGCCATGGCATTCTCTCTTGCT GCCTGTGCTGATGTTCCTGTCACTATTAAGGACCCAGGC TGCACCCGCAAGACCTTCCCAGACTACTTTGACGTCTTG GAACGGTTTGCCAAGCATTGAGCGGCTATCTGCAGATTT TTCATAAAGTATGCACGAAAGTTTCAATTTAAGAAGATA CCGAGTTGATTATATGCTTTCCGCATAAGTTATTGTCAC ATTTTTTGTATTATGTTTGTAAGATCTTAGGCAATAAGA TATACTGTTAGAAATTATGTGTATCTGATTATTTAGAGA TGTATACTTGGGTCAGTTGAAATTGTACGAGAAAGGTCT GGATTTCGAAAAAAATGTGATCCAGACATTAGTGTGGTC TGAACTGAAGCAAGTACTCCCTCCGTCTCATAATTCTCA CAACTCTTGCTATTATTTGTGAGAAATAAAATATTCAAG TGTTGCGAGAATTGTGTGACAGCGGGAGTAGCAACTTTT CAAGTTTGGAATTAATTTTGTGATGTGAGTTTTTTGTGT ATTCTTTGTTTTCCATCAAACCCTCCTCCAAAGTACAAA CCCAATTCATGGTATGGTTGATGCAACAGCAATATGTCA 181 WO 2013/039990 PCT/US2012/054789 AAATCAGTGTTTGTGATGTTGGCTTCTCTACTTCATTAT CTCTTCTTGTTCAGTATGATTTCGCAATCTCTTCCCGTC AAAATCCCTTCTCCTCTGATAATCGCAGAAATCGTGTCT TCCCCTCGGTGTGTATCCACCTCTTAAAAATTTGTTGAG AGTTGAAATGTGCTGCCACTGGATTCATCCTTTAGGGCG AATTTTGAACGGATTTTAGGTGGTTAGGATTCAACCCCT GTCAATTATAGTTACGGGAATTAGACACGCGTTCTGCCT TACCAACCCCATTTTTTTGTCACTATATCAAGTATCCAT TGCTAGTTGTAGTCATGTAGTAGGGTCTGAAATCTAAAG CAAAGTAGCAAGATTGCAACAACAGGAACAGCAAATAAA TCTAG 106 Lolium Genom 6967 GATAAACTGATCTCTGTTCCTTATGTTGAAATGACATTG multiflorum ic AGATTGATGGAGCGTTTTGGCGTGACGGCAGAGCATTCT GATAGCTGGGACAGATTCTACATTAAAGGAGGACAGAAG TACAAGTAAGTTTTGAATTGTTCTGCTTATTCTAAGCAT TTGTCACATTTGACTTCTGGATAAACTACAGAATTGAAT ATTAGAAAGAAATATTGACTGCTCAAGTAACTTTATTTA TCTGGAAATGACCATGCTGTTATTAGCTATGAAGTCAAG CTTTACTAGGAAATCAGTGCCTTAGGCAATTGACTATGC TACTTACAATGCACTGGCTGCACAGCTATGTTTTCTGGT GCATAAACATTTATTCATCTGGCTAGGACCAAACTTTTA GTAGCTATGAACTGTACTAGGAAATCACTGCCTAGGCAA AACTCCACAATTTACAATGACATTGCATGGTTTTATTTT CTTGTGCATAAATTTGGTCACATCAGAAGTGCCATCCAT CTAAAAAATCGGCGAAAATTGAGAACATAGGCAGCTTAA TGACAGCGGTTTGGCAATAAGCATTTTTTGCAGACGATT CTTGCTTTGCTTCTTTTAGCCCTTTTTATTGTTATATAC CCTGCCAAATGTCGCATCAGGATATCTGCTGCCAAATGT TGCATCAGGATATGGATCGTGGTTTTACTGAGCATACTT CACTGATGTAATTGAAAACTGTCAGTTCAAACTTCATAA AAGTTGTAGTAATGGCTTCCTAACAAGCCCTCCCTTGCT CTGGAATTTACAATTGACAGGTCCCCTGGAAATGCCTAT GTCGAAGGTGATGCCTCAAGTGCGAGCTATTTCTTGGCT GGCGCTGCAATCACTGGAGGAACTGTGACTGTCCAAGGT TGCGGCACCACCAGTTTGCAGGTAGAACTGTACTATCAG TTTTTACCATTGGTTAAGCATACTTGCAGTATAACATAA TCAAAGATATACTGCTGTCAACCAAACATGCTTTAAGTG GACATTCATTTATGAATCTATAATATAACTACAGTACCG TAATTTGGTTTTCTTGTGCTATATCCCTGATGATGCCTA ATATTGCAGGGTGATGTGAAATTTGCTGAGGTACTAGAA ATGATGGGAGCAAAGGTTACATGGACCGACACTAGTGTA ACTGTTACTGGTCCACCGCGTCAGCCCTTTGGACGGAAA CACCTTAAAGCTGTTGATGTCAACATGAACAAAATGCCT GATGTTGCCATGACTCTTGCCGTCGTTGCCCTTTTTGCC GATGGTCCAACTGCTATCAGAGATGGTAAACCGTCTTAT GTGTTGCTGTTGATTTCATTTGGATGGATTTAGCTACAG CGCATGATTTGTTGCTGACACTTGTCCATTCTCCTCTGC AGTTGCCTCCTGGAGAGTGAAGGAAACCGAGAGAATGGT GGCAATCCGGACGGAACTAACAAAGGTAGCACACCTATC TCCACTTCTTATATTTCAGCTCACTGTTGCACTCCCCAG TGCTTAGTCTCACCTGTTGTGTGCCTCGTGCTATAGCTG GGAGCAACGGTAGAGGAAGGCCCGGACTACTGCATTATC ACACCACCAGAGAAGCTGAACGTCACGGCGATCGACACC TACGATGACCACCGGATGGCGATGGCCTTCTCCCTTGCC 182 WO 2013/039990 PCT/US2012/054789 GCTTGTGCTGAGGTGCCTGTCACGATCAGGGACCCCGGG TGCACCCGCAAGACCTTCCCCAACTACTTTGACGTGCTA AGCACCTTCGTGAAGAACTAGCTCCTTTTGTAGCCTGTC CATGGTTTGAGGAAATTTTTACTGTTTTGGTCCTTCTTG CGAAATGATTTATGAGTCTGTAATACTAGTTTTGTAGCA TGTCGTGGGCCTTTTGAGGTAAAATGAGTTGTAATGCAT ACCGAGTTCGTTTTGAATAAGAAGCAAGTTAGGCGTACC ATACTGTGATCTAGATGTTCGTCTTTCGTTTCCAGAAAT ATTATGTTGGCTGCTGGTACTCGAGTGTGTTCGAAAACA ACATGATAGCCATGGGATTTGGGAGATGACATGTGGGTA TGTGGCTACTTGAGGAAGATCTTCATCAAAGCAACCAAG AACACCAGCCGATGGTAAAACAGTGCAGCTTGCACGAAG AACGTTTGCCTACACTGCTTGGTAAAAGCGAAGGTTTGG TTTGATAAATTTCTCAGCAGTATTTTGTAATGCTTCGAT GGTAATTCTTCTACGCAAACCATCAGCCTCAATAGTAAT CCTGTGCAGTATTTTTTTAGTAGCCCTCGGCACGCTTGA ACTGTAATTCTTCAACTAAAAACTCAGCTTGAAAATAAT TATTCGTTGTTAATTGTTCAACAATAATTTTCCTAGCGC TTAATTGGTGAGAGGTAATTCTCAGCAGCAGTAATTCTC CCAATGCAAAATCTTTAACTCCAATTGGAGCGGCTTCTC CACACTCCACCGTGCTTCACTGTAGAGCTTCATCTTTTA CCAACCTGGACCCGCGGAACAAGAAGGTCATGGTTACAT GGACCATGGTACAGGAAACAGAGCAGGCCACACGAGACA CGACTATAGCAGCACATCGTTGGTTCCCCACAACCGATT CCAGCGACTGGCCTGGCGGCGCGCATGTAGAGCAGGCGA CCGGTGAGACACAACGGTACTTCACCGGCGGCTCCTATG GATTTCACATGGAGGCTGTGAGCAGGTAAGTGCGTGTTT TTTTCTCGATTGGAAACTATGGGTGAGAAATTTGTCCCC AATTATGGCGGGCGGCCGATTATTTCTGCCATTGCGGTG CGCCAATCTACGAGGGCACAGTTGTTGTGCCTGAAAATG GTGCAAATCCATCCGTGATGCAGTGCTGGAAGGCGGTGC CTGCAGCCATGTCGGGTCAGTTGAGCCAGATCCATCCGT GGCGGGCATCTTGCAAGTGCTACCTAGCAGGTGCCGACA ACGGAAAAGGGGACGGGGAGGCCGATTCAACGCAGTGCA CCATGAATCAGACATCGATGGACCGCGCCAAGAGGTAAA AAAGTAAATCATATTCGTAATTTCTGAAATTTTGGAAAA TGTCAGTCATTGTGTAGGTGGATAACATATAAAAAGCAG CCCAGGAATCTGAGTTTGGTAGACCGGTGTAAGCAACAC ATGAGAATTGGCCAGGATAAAAGAAAAATCATGTCGATT TGAGTAAGCTGATCGTCCATGGTCAGTTAAAGAATTGTT ATTGTGAATGATGCAGTGATGTGAAGTTAGTGAACATTA GAAGGGGTTGTGCGTTGTAGTTAAAGTTCAAATTTAGCT GGAAATGGCATGAATCTGAGCCAGGTTGTGAACTCCTGA GGTATGAAGTTCTGTATAGAAAAGAAATTGTTCAGTTGT TGAGTGAACTGGATGTAGGTAAGTGGCAGTGATGATAAG GTAGAATTTACACATACAAAGATAGCATGAATTTGTAGC CCTGGCTAGCAGGTTGCCAACAGTTATCAGTTTGTGCAG TT GCGT GTAAAAAGGAAAAAT GATGATGAAAGAATTAGT ATGAGTGTTCTGTAGACCTAACTAACCTATGGTAGATGT TGCGAACCTGTGCAGGATAAAGATGGGTCAGGCGCCATC AGACATGGCGCCATGTCTTTCGAGACCGAGTGCTCTTGA GAAATCAATATGTGGCTACACAGAAAAGCTAGGTTGGGA GGGGTGCACATGGAGACACAATGGTTGCCGGTGCAATAG CGGGTACAGAACAGACACAAAAATACCTTTGATGTTTGC 183 WO 2013/039990 PCT/US2012/054789 ATGCATTGGCTGAACAGAATTAGATCACGTATTTGCAGG GGTTCCAGAAAAAAATGCAGCACACTGAGGCCGAGGGGG TTGCTGCTGGATTATCATCCGATGAAATATTTACAAGAT AACTACATGAGCTCTACAGTTTGAACAGTACGTTCCAAT ATCACTAGTTTTAATAATTTATCCAAACACATCTGTAAA GAAAATGCAGATAATAACGTTGATCTGACATGTTTGGTC AGTTCTTGACGTGGACAAGGTAACAAGTGAAACAATAAA AGGCGCTACAGTCTCGGCACACGCTAGTCGAGTTGCATC TCTCGGAGGAAAAGGTGCTCCTAAATTTTCAGCAGGTGA GTTCTCCTTCTGTTTGCAGCACACCTCGTGTTTGTATTC CCCATGATGGAAAAATTAAGGGGTATGCATGATTTTAAT TCAGAAAATTGTGTGGCTCCGCAGATGCCCCGTCCAATT GTGGAGCTGTTGTGATATCGAGGAACTAAAGTGCCAGAA ATGGATGATGACGTGCTAGATGCTCCAGGGGCTGAAACG GTGGCGTCAAACCCGTCCATGCCTATCTGAGGTAGGAGA AACAAACGAGATCACACTGGTTTACCTTTGAATGCACTA TGCACCGAAGAGAGTTCGGTTTGCATCTGGTGCCACCTC AGTGGGTGGACAATCTAGCATGAGAGGGTAGGAATCTCA TGGACGCATGTAATTTTCACAGAGACCTGTGTTTTATGT TGTGGGGTGTGCAAATTCAGTAACCTAATGATGCCTACT TTTTGTCAAGAAAAATATAGTTAATGAGTCTGGCTGATC GTGAGGAACTGACAGCTACCTAATCGGGCAGTGGTAATG GGTTTAGCTGTGCATATTTGTGATAGTGTGCTCATAGAT TCTTCTAATTCTGATAATGGTTTACGGTTATCCGTAGGT CAAGGAGGACATAGTGATAGGGAGTGCAAAGACGACCAG TACAACTCATCATGGTGCATCAGCAGCAGCTGGTAATTC ATGAATTTGAGTATATACCTGGGATACAAAAGGTGAGGG TTGGATAAGTCTTAATGCCATGTTATACTGCGTATTCAG CAGGTGCAGCGAGTGGCGACGTATCCAGGGGGCGTCGTC CAGTTGAAGCCTCGGCACTATAACTGGTATGTCGTGCTC AAGTGGTAAT GACATTAC TAT GTGATGGT GAAAAAAC TT TGCAGTTGAGTGTACTCCGAATCTGATATGGCTAGTTGT TGCGCACTGTCTGAAAGTTGTGCTTCTACCCTTTGCTGT AGGTATACGGACTTTCGTTCAGCTTCCAGGCATAGAGAA GCACATTCGGTGCTCATTCAGATAGACGATAAGGATTGC GCGAAGAGAGAGCTAGACTAGCAGTTCCCAATCACAGAC GATGCAGGGGTGCAGCATGATCAGCCAGTCCTTCAATAT GGATGAGATGGGCGAAGCCATGGATCTCGGGGAATGTAT CCACAAAGATACCACCCCTGTTCCGCAATGAAGGAGTTC TAGTCGTGAGCAATGCTACATCTAGGGGCTCGTTTTTAC AAAATCGAACTTACGGGCTGACGTGGAGAATCATGGAGG GATTAAGGTTCCTCAAATCAAATCATGGGAGGAGAAAGA TTTGCACCACCCACGTTCATCCACCTCATCCCGTAAAAC CACCCCGTAACAAAAATCCCATAGGTGTAGGATTATTGG TTTATTAATCGGGATACTGACTCCAATACTCACAAATAT ACGCACATGGGCTTCCATCTGTCTGGGCATGATTGGTCC AGGACGCGAGTGTAGATGCACCCGGGAGCCAAACCACAT TTCCTTCTCTCGAAGCTAAAACTCGTTTAGTTTTTCATT AGTTAGGCTCAGGTTATTCAGATCTTTTTTACGTTGCTA GCAATGACAATTGTCACAATTCCAAGTGTCATGCAGCAA AGCAGACGCCACTCTTTCACGCATAGAACAACGATATAA TCTGCAGAGATACTGCCGAAATGCTAACAATATCAATAG CAAGCCATATATATAAACTTCCAATCAGATACACCAGAG AGCAATGAAAATTGGTGATGATGATAACTCAGACGATAG 184 WO 2013/039990 PCT/US2012/054789 GGACTCAGAATCGTGATGCAAAGAACCTAGTCATACAAA AACCGGTCTCATACTAGAAATTCAAAGACATGTCATTCT CTGGTGTCTCTCCACCTTTTTAATAAACAGATAAAAGGC ACTGGGTAGGATAACTACTGGTCGGTGATGGTCACTTCG ACCTCGACACCAGGCTCGATAGTGATAGAGGTGATCTGC TTCACAACGTCTGGGGAGCTGACAAGGTCAATCACCCTC TTGTGCACCCGCATCTCGAACCGATCCCAGGTGTTGGTA CCTGATTTAACAAAACAGAGTTAGCCATTTCATTTTGGA AGATGATGAAGCTTCAGCATAGCTGCAGGTAATGAATGA TCTGTGACAGGCTGAGCATCAGTTTTAAAAAGCTCGATT TTGAAACATCAAATGTATCAGACAAAATCATATGGAATC ATCATCTGCTCAGCCCATCCACAGGATACATGTTTCCTT TCCAAAAAAATTAAATCAGGCGTTATTGAACAACAAGAT CTTACTGCCAGTAGTGCTGGAAGAACCACTAGACGAATT GTATGTAGAGCAACAAACAAGCATTATACAGGCTAATCA TCAGTTTTAAAAAGCTCGATTGTGATTCCTCAAAGAAAA TCTCAGGAATAACTTGGTTTAGCATCATCTGATCAGCCC GTTACAGAACAAAGGTGTAAAAACTAGCAGCACACACTC TTAACAGTAGAGACTGGGTTACATAAATGGAGGTAATAT GTATGAAATACAACTGAGGTATGCTGAGAAGTGTTCATG TTTAGGATCACAAATAAATCAGCAGATCGCCAGAAGCAA TGAATGTACTTGCTGCAGATTAGCCCCTAGCTAACTTAC TAGAAAAACCCAAGCATCAGTTTTAAAAAGCTCGGTTTA AGATACTTCAACGATGGAACATCTCAGTAGCATCTCCTT GTAACATCACATGCTCAGTTTACAGTAAACGATTCGCCA TGTAGACTCCATTTTACTTGAAATCATACCACACTAACA GAACTACCACGAACATAATAAAAAAGCGATGACATGCTA AGCATCAGTTTTAAAAAGCTCGATT 107 Lolium Genom 1093 GTAGTAGCTGCTGGTGGAAATGCGACGTATGTTTCTTTT multiflorum ic TTTTATCCTTACGGGAATAAGTATGAGTTCCGTGGTTAT GCTTTGAGACTGATGGTTTACGTCTCTCTTCTGAACTTC AGTTATGTTCTTGATGGAGTACCAAGAATGATGGAGCGT CCTATCGGTGACTTAGGTGTCGGTTTGAAACAACTAGGT GCGAGTGTTGATTGTTTCCTCGGCACTGACTGCCCACCT GTTCGTATCAACGGCATTGGAGGGCTACCTGGTGGCAAG GTTAGCTTCATGAACTTCCATGTTATACGCTTTTGTACA AACATTTCACTTGTCTGGAGAAAAAACAAGATTACTGAC AGAGTGAGAGTAGTACGGTGCAATGCGACCACACAATAA CTCCAAAATTGCCATAACCAATAGGCCCTTTTTCGTGTA AAACAGATATGCTGATTGTATTGTGGTCTTAGATCACAT GGGTCTATCATGAACTAGCACTTAACATTGAACCACATT CCACAGGTTAAGCTGTCTGGTTCCATCAGCAGCCAATAC TTGAGTTCCTTGCTGATGGCTGCTCCTTTAGCTCTTGGG GATGTCGAGATTGAAATCATTGATAAACTGATCTCTGTT CCTTACGTTGAAATGACATTGAGATTGATGGAGCGTTTT GGCGTGACGGCAGAGCATTCTGATAGCTGGGACAGATTC TACATTAAAGGAGGACAGAAGTACAAGTAAGTTTTGAAT TGTGCTGCTTATTCTAAACATTTGTCCAAACATTTGACT TCTGGATAAACTAGGGAATTGAGCATTGGAAAGAACTAT TGGCTGCTCAACTTTATTCATCTGGAAATGACCATACTG TTATTAGCTAAGTCAAGCTTTACTATGAAATCAGTGACT CTGCTACTTACAATGCACTGGCTGCACAACTATGTTTTC TGGTGCATAAACTATAGTCTGCCCAAATAACTACCAAAC TTGTAGTAGCTATGAACTGTACAAGGAAATCAGTGTGGC 185 WO 2013/039990 PCT/US2012/054789 AAAACTCCGCTACTTACAATGGCATTGCATGGTTATATT TTGTTGTGCATAAACTTGGTCACATCAGAAGTGTCATCC A 108 Lolium Genom 983 CATTGAAAGTTCTATTATTATTTTGAGTTTGCATCTTAT multiflorum ic GTTGTTTTTCCTTTGTGATTTTATCCATTTTCTTAACTA GTTATTCGTTTCCTGAAGTTTTTAGTGTCATAACTCCTA ATCACAATCATGCTACAGGGCACAACAGTGGTCGACAAC TTGCTGTATAGTGATGATATTCTTTATATGTTGGACGCT CTCAGAACTCTTGGTTTAAAAGTGGAGGATGATAGTACA GCCAAAAGGGCAGTCGTAGAGGGTTGTGGTGGTCTGTTT CCTGTTGGTAAAGATGGAAAGGAAGAGATTCAACTTTTC CTTGGTAATGCAGGAACAGCGATGCGCCCATTGACAGCT GCGGTTGCCGTTGCTGGAGGAAATTCAAGGTTTGTCCAA TTATATTCTTTATGTGAGTGTTGTTTTTTGTGTTAGTTT CAATCATGAAGGTACTAGTGCAGAAGCCGTACCCCTGAA ATTTTCTTATTTTGTATATATCAATTGGTAATTGATGTA AGATATTTTTCCGAGAGGAATAAAAAACAGGGGGATAGA GAATATTAAAGTATTGTTCTATCACATTAACTTTTTATC AAAGGTGTACATTGTGTTTGTGAAGTTTATAGAGCTAAA GGGATGGAAGGGAAGGGGATTGAAGAAGAGGAGAAAAGA AGAAGATCCTCCTTTGAATACCAAGGTTTGAACGGAAGG GAGAAGGAGGAAACTCTAAACAATATGGAGATGAACTGA TGAAGTTTTTGGATCAGAACCGCTTGAGAATCAGAGTTA AGCCATGTGAAAGTCTATGAGCATGACTTCACCTGGTTA ATAATTTTAAGCTCTCAACTTCTCATCCTCTTTTCTTTG TCGAAAATGTCATGTCTTCATGTGATACGTGCTTACATA ATCGTTTCTTTTGTAAAGCGATTGTCTCTCCAGATTTCT CCCCTTACGAAAATAATCCTTGAAGGTTGAAGAAATCCC TTCATTTC 109 Lolium Genom 591 AGTCTACACCAACCCACTTTCTCTTTGCCCACCAAAACT multiflorum ic TTGGTTTGGTAAGAACTAAGCCCTCTTCTTTCCCTTCTC TCTCTTAAAAGCCTAAAATCCACCTAACTTTTTCAGCCA ACAAACAACGCCAAATTCAGAGGAAGAATAATGGCTCAA GCTACTACCATCAACAATGGTGTCCATACTGGTCAATTG CACCATACTTTACCCAAAACCCAGTTACCCAAATCTTCA AAAACTCTTAATTTTGGATCAAACTTGAGAATTTCTCCA AAGTTCATGTCTTTAACCAATAAAAGAGTTGGTGGGCAA TCATCAATTGTTCCCAAGATTCAAGCTTCTGTTGCTGCT GCAGCTGAGAAACCTTCATCTGTCCCAGAAATTGTGTTA CAACCCATCAAAGAGATCTCTGGTACTGTTCAATTGCCT GGGTCAAAGTCTTTATCCAATCGAATCCTTCTTTTAGCT GCTTTGTCTGAGGTATTTATTTCTCAACTGCGAAAACAA TCTCTATTTGATATTGGAATTTATATTACATACTCCATC TTGTTGTAATTGCATTAGTACATACTTATGTTTTGACCT TTGTTC 110 Lolium Genom 514 GGGCGGTGCTCTGGAGAAGGTCGTGCTGCAGCCCATCCG multiflorum ic GGAGATCTCCGGCGCCGTGCAGCTGCCCGGCTCCAAGTC GCTCTCCAACCGGATCCTTCTCCTCTCCGCCTTGTCCGA GGTGAGAAAACAAGCAGACAAAGCCCCTCTCCCTACTTC TCCCCTTTGTGTGAATTGGGTGCCGAGATGGTTTAGGAG CACCTTATCATGCTTGGTGCTCGTGAGATCATAAGATTT TTTTCTTTTTACTTAAAACGATCTAGCCATAGGATTTAG TTCAAGGTTACTCTTCTTAGTAGCCAATTCCTATATTCG TTTATCGAATCGTTAGAATTATGTAGTTAGTTGGATCAA 186 WO 2013/039990 PCT/US2012/054789 TATTATATGTGGCCTTGGATGAGCAAAAGTCAGTTTATT CACTTTCCACTCATCGGAATATTATAGTGCAGCATGTCC TGTCAACTTATTTGCAGTACGATAAGCAATTGAAACTGC TTTGCTTCGCTGTCATCTCTTGCTGATCATTAACTGGCT TTTGCTC 111 Lolium Genom 460 CAAGATATACAACATGCAAATTTTGCCATCGCAAAAGGT multiflorum ic TTTCACGAGCTATAAGGTACTACTAAATCTAGGATCCTC CTGGGCTTATTCAGTTTAGATCCGTTGGAATATTATAGT GCAGCATGCCCTGCTAACCTTTGTACAGTAAGATAAGAA ATTGAAACTGGTTTATTTCGCTGTCGTCTCTTGTTGATC ATTAACTGGCTTTTGCTCATCAGGGAACAACGGTTGTGG ATAACCTGTTGAACAGCGAGGATGTCCACTACATGCTCG AGGCCCTGGACGCGCTTGGGCTCTCAGTGGAAGCAGACA AAGTTGCAAAAAGAGCTGTAGTCGTCGGCTGCGGCGGCA GGTTCCCGATTGAAAAGGATGCCAAGGAGGAAGTAAAGC TCTTCTTGGGCAACGCTGGAACTGCGATGCGGTCATTGA CGGCAGCTGTAGTAGCTGCTGGTGGAAATGC 112 Lolium Genom 1377 ACCTGAATGGGCACTTAGTATTCATGTACCTACATTCAA multiflorum ic GACATACAACATGCAAATTTTGTTATCGCAAAAGGTTTT CACGATCTGTAAGACACTACATCTAGGATCCTCCTGGGC TTATTCAGTTTCGACCCGTTCGAATGTTATAGTGCAGCA TGCCCTGTTAACCTTTGTACATCAAGATAAGAAACTGAA ACCTGTTTACTTCGCTGTCGTCTCTTGCTGATCCTTACT TTCTCTCATCAGGGAACAACGGTTGTGGATAACCTGTTG AACAGCGAGGATGTCCACTACATGCTCGAGGCCCTGGAC GCGCTCGGGCTCTCCGTGGAAGCAGACAAAGTTGCAAAA AGAGCTGTAGTCGTTGGCTGCGGCGGCAGGTTCCCGATT GAAAAGGATGCCAAGGAGGAAGTAAAGCTCTTCTTGGGC AACGCTGGAACTGCAATGCGGCCATTGACGGCAGCTGTA GTAGCTGCTGGTGGAAATGCGACGTATGTTTCTTTTTTT TATCCTTACGGGAATAAGTATGAGTTCCGTGGTTATGCT TTGAGACTGATGGTTTACGTCTCTCTTCTGAACTTCAGT TATGTTCTTGATGGAGTACCAAGAATGATGGAGCGTCCT ATCGGTGACTTAGGTGTCGGTTTGAAACAACTAGGTGCG AGTGTTGATTGTTTCCTCGGCACTGACTGCCCACCTGTT CGTATCAACGGCATTGGAGGGCTACCTGGTGGCAAGGTT AGCTTCATGAACTTCCATGTTATACGCTTTTGTACAAAC ATTTCACTTGTCTGGAGAAAAAACAAGATTACTGAGAGT AGTATGGTGCAATGCGACCACACAATAAATTTGAAATAG CCATAACCAATAGGCCCTATTTTGTGTAAACAGATATGC TGATTGTGTTGTGGTCTTAGATCACACGGTCTATCATAA ATTAGCACTTAACATTGAACCACATTCCACAGGTTAAGC TGTCTGGTTCCATCAGCAGCCAATACTTGAGTTCCTTAC TGATGGCTGCTCCTTTGGCTCTTGGGGATGTTGAGATTG AAATTATTGATAAACTAATCTCTGTTCCTTACGTTGAAA TGACATTGAGATTGATGGAGCGTTTTGGTGTGACGGCAG AGCATTCTGATAGCTGGGATAGATTCTACATTAAAGGAG GACAGAAGTACAAGTAAGTTTTGAATTGTTCTGCTTATT CTAAACATTTGTCACATTTGACTTCTGGATAAATTAGAG AACTGAACATTGGAAAGAACTATTGGCTGCTCAAGTAAC TGTATTCATCTGGAAATGACGATACTGTTAGTAGCTATG AAGTCAAGCTTTACTAGGAAATCAGTGCCTAGGCAATCG ACTCTCCTACTT 113 Lolium Genom 1107 CCTACTTACAATGCACTAGCTGCACAGCTATTTTTTTGG 187 WO 2013/039990 PCT/US2012/054789 multiflorum ic TGCATAAACTATTGACTGCTCAAATAACTTTATTCATGT GGATAGGACCAAACTTTTAGTAGCTATGAACTGTACTAG GAAATCAGTGCCTACGCAAAACTCCGCTACTTACAATGA CATTGCACGGTTATATTTTCTTGTGCATAAATTTGGTCA CATCAGAAGTGCCATCCATCTAAAAAAATCGGCGAAAAT TGAGAACATAGGCAGCTTAATGACATCGGTGGCAATAAG CATTTTTTGCAGACGATTCTTGCTTTGCTTCTTTTAGCC CTTTTTATTGTTATGCCCTGCTGCCAAATGTCGCATCAG GATATCTGCTGCCAAATGTTGCATCCGCATATGGATCCT GGTTTTACTGAGCATACTTCACTGATGTAATCGAAAACT GTCAGTTCAAACTTCATAAAAGTTGTAGTAATCGCTTCC TAACAAGCCCTCCCTTGCTCTGGAATTTACAATTGACAG GTCCCCTGGAAATGCCTATGTAGAAGGTGATGCCTCAAG TGCAAGCTACTTCTTGGCTGGCGCTGCAATCACTGGAGG AACTGTGACTGTCCAAGGTTGCGGCACCACCAGTTTGCA GGTAGAACTGTACTGTCAATTTTTACCATTTGGTTAAGC ATACTTGCAGTATAACATAATCAAAGATATACTGCTGTC AACCAAACATGCTTTAAGTGGACACTCATTTATGAATCT ATAATATAACTACAGTACAGTAAGTTGGTTTTCTTGGGC TATCTACCTGACGATGCTTAATATTGCAGGGTGATGTGA AATTTGCTGAGGTACTAGAAATGATGGGAGCCAAGGTTA CATGGACCGACACTAGTGTAACTGTTACTGGCCCAACAC GTCAGCCCTTTGGAAGGAAACACCTAAAAGCTGTTGATG TCAACATGAACAAAATGCCTAATGTTGCTATGACTCTTG CCGTTGTTGCCCTTTTTGCAGATGGTCCAACTGCTATCA GAGATGGTGAACCCTCTTATGTGTTTCTGTTGATTTCTT TTGGATGACTTCCGCTACAGCTTAAGATTTGTTCCTGAC ACTTGTCCATTCTCC 114 Lolium Genom 480 CTTGTCCATTCTCCTCTGCAGTTGCCTCCTGGAGAGTGA multiflorum ic AGGAAACCGAGAGAATGGTGGCAATCCGTACGGAACTAA CAAAGGTAGCACACCTGTCTCCACTTCTTATTTTCAGCT CACTGTTGCACCCCCCCAGTGCTTAGTCTCACCTGTTGT GTTCCTCGTGCTATAGCTAGGAGCAACGGTAGAGGAAGG CCCGGACTACTGCATTATCACACCACCAGAGAAGCTGAA CGTCACGGCGATCGACACCTACGATGACCACCGGATGGC GATGGCCTTCTCCCTCGCTGCCTGTGCAGAGGTGCCTGT CACGATCAGGGACCCTGGGTGCACCCGCAAGACCTTCCC CAACTACTTTGATGTGCTAAGCACCTTCGTGAAGAACTA GCTCAAGGAAAATCTACAGCATATCGCCTTTGTACTTTT GTAGCCTGTTGTTCATGGTCTGAGGAATTTTTTACTGTT TTGATCTTCTTG 115 Lolium Genom 318 CCACGTCCGTGGCCGCGCCCGCGGCGCCGGCCGGCGCGG multiflorum ic AGGAGGTCGTGCTGCAGCCCATCCGGGAGATCTCCGGCG CCGTGCAGCTGCCCGGCTCCAAGTCGCTCTCCAACCGGA TCCTTCTCCTCTCCGCCTTGTCCGAGGTGAGAAAACAAG CAGACAAAGCCCCTCTCCCTACTTCTCCCCTTTGTGTGA ATTGGGTGCCGAGATCGGAATATAGCTAGGTGCTTGTGA AGTCGTGAGATCATAAGATTTTTTTTCCTTTTTACTTAA AACGATCTAGCCATAGGATTTAGTTCAAGGTTACTCTTC TTAGTA 116 Lolium cDNA 1284 CAGCTGCCCGGCTCCAAGTCGCTCTCCAACCGGATCCTC multiflorum CTCCTCTCCGCCTTGTCCGAGGGAACAACGGTCGTGGAT AACCTGTTGAACAGCGAGGATGTCCACTACATGCTCGAG GCCCTGGACGCGCTCGGGCTCTCCGTGGAAGCAGACAAA 188 WO 2013/039990 PCT/US2012/054789 GTTGCAAAAAGAGCTGTAGTCGTTGGCTGTGGCGGCAGG TTCCCGATTGAGAAGGATGCCAAGGAGGAAGTAAAGCTC TTCTTGGGCAACGCTGGAACTGCAATGCGGCCATTGACG GCAGCTGTAGTAGCTGCTGGTGGAAATGCAACTTATGTT CTTGATGGAGTACCAAGAATGAGGGAGCGACCTATCGGT GACTTAGTTGTCGGTTTGAAACAACTAGGTGCGAATGTT GATTGTTTCCTCGGCACTGACTGCCCACCTGTTCGGATC AACGGCATTGGAGGGCTACCTGGTGGCAAGGTTAAGCTG TCTGGTTCCATCAGCAGCCAATACTTGAGTTCCTTGCTG ATGGCTGCTCCTTTGGCTCTTGGGGATGTCGAGATTGAA ATCATTGATAAACTGATCTCTGTTCCTTACGTTGAAATG ACATTGAGATTGATGGAGCGTTTTGGCGTGACAGCAGAG CATTCTGATAGCTGGGACAGATTCTACATTAAAGGAGGA CAGAAGTACAAGTCCCCTGGAAATGCCTATGTCGAAGGT GATGCCTCAAGTGCGAGCTATTTCTTGGCTGGTGCTGCA ATCACTGGAGGAACTGTGACTGTCCAAGGTTGCGGCACC ACCAGTTTGCAGGGTGATGTGAAATTTGCTGAGGTACTA GAAATGATGGGAGCGAAGGTTACATGGACCGACACTAGT GTAACTGTTACTGGTCCACCGCGTCAGCCCTTTGGAAGG AAACACCTAAAAGCTGTTGATGTCAACATGAACAAAATG CCTGATGTTGCCATGACTCTTGCCGTTGTTGCCCTTTTT GCTGATGGTCCAACTGCTATCAGAGATGTTGCCTCCTGG AGAGTGAAGGAAACCGAGAGAATGGTGGCAATCCGGACG GAACTAACAAAGCTGGGAGCAACGGTAGAGGAAGGCCCG GACTACTGCATTATCACACCACCAGAGAAGCTGAACGTC ACGGCGATCGACACCTACGATGACCACCGGATGGCGATG GCCTTCTCCCTCGCTGCCTGTGCAGAGGTGCCTGTCACG ATCAGGGACCCTGGGTGCACCCGCAAGACCTTCCCCAAT TACTTTGACGTGCTAAGCACCTTCGTGAAGAACTAG 117 Lolium Genom 302 AAACAACATCATATGGTTTCTTTTGTCTTTATGACTAGA rigidium ic CCACTCTTTATTATTCCTTGTATTGGGATCTTATTTTGA ATGGTTGTTTAGCCTACACCTCATGTTCTAGATTTTGTT CGTATACCAGACTTTTCTTGATTGCGATCTATTTGTCCC CTGGATTTTGCATAGGGTGATGTAAAATTTGCCGAAGTT CTTGAGAAGATGGGTTGCAAGGTCACCTGGACAGTACAA TAGCGTAACTGTTACTGGACCACCCAGGGAATCATCTGG AAGGAAACATTTGCGCGCTAATCGACGTC 118 Sorghum cDNA 608 GAGGAAGTGCAGCTCTTCTTGGGGAATGCTGGAACTGCA halepense ATGCGGCCATTGACAGCAGCTGTTACTGCTGCTGGTGGA AATGCAACTTACGTGCTTGATGGAGTACCAAGAATGAGG GAGAGACCCATTGGTGACTTGGTTGTCGGATTGAAGCAG CTTGGTGCGGACGTTGATTGTTTCCTTGGCACTGACTGC CCACCCGTTCGTATCAATGGAATTGGAGGGCTACCTGGC GGCAAGGTTAAGCTCTCTGGCTCCATCAGCAGTCAGTAC TTGAGTGCCTTGCTGATGGCTGCTCCTTTGGCTCTTGGG GATGTGGAGATTGAAATCATTGATAAATTAATCTCCATT CCCTATGTTGAAATGACATTGAGATTGATGGAGCGTTTT GGCGTGAAAGCAGAGCATTCTGATAGCTGGGACAGATTC TACATTAAGGGAGGTCAAAAATACAAGTCCCCCAAAAAT GCCTATGTTGAAGGTGATGCCTCAAGTGCAAGCTATTTC TTGGCTGGTGCTGCAATTACTGGAGGGACTGTGACTGTT GAAGGTTGTGGCACCACCAGTTTGCAGGGTGATGTGAAG TTTGCTGAGGTACTGGAGATGAT 119 Lolium Genom 647 CGCCACGTCCGTGGCCGCGCCCGCGGCGCCGGCCGGCGC 189 WO 2013/039990 PCT/US2012/054789 rigidium ic GGAGGAGGTCGTGCTGCAGCCCATCCGGGAGATCTCCGG CGCCGTGCAGCTGCCCGGCTCCAAGTCGCTCTCCAACCG GATCCTTCTCCTCTCCGCCTTGTCCGAGGTGAGAAAACA AGCAGACAAAGCCCCTCTCCCTACTTCTCCCCTTTGTGT GAATTGGGTGCCGAGATGGGATTTTAGGAGGGTTAGGTG CATCTTATCATGCTAGGTGCTCGTGAGATCATAAGATTT TTTTCTTTTTACTTAAAACGATCTAGCCATAGGATTTAG TTCAAGGTTACTCTTCTTAGTAGCCAATTCCTATGTTCG TTTATCGAATCGTTAGAATTATGTAGTTAGTTGGATCAA TATTATATGAGGCCTTGGATGAGCAAAAGTCAGTTAATG GTAATTAGAATTATGTAGGACCTGGTGATCCTCTTATGT CAGTCTGATGGCTTCCTCATGAAAGTATTACGCTGCAAC GCTGTCATGGACACCTAGTATTCATATACCTGCATTCAA GATGCACGACTTTCAAATCTTGTTATCGCTAAAGGTTTT CACAAGCTATAAGATCCTAAATCTAGGATCCCCTCCAGA GTTTATTCACTTTCCACTCATCG 120 Lolium Genom 4472 TCCTCTCCGCCTTGTCCGAGGTGACCAAACAACCCGAAA rigidium ic CGCTTCCCCCTCCTCCCCTTCCTTTGGGGTGAATTGGGT GTACTAAAGATGGGATTTTTGGAGGTTTAGGGGCGCACT TGTATCTTGTCATGCTAGGTGCTGGCCAGATCATAAGAT ATTCTTTCATTCTTATTAAGACGATCTAGCCATAAGACA TATACTTAAGAAGGTAGTCTGTTCAGTAGGCAATTCATA AGTCTGTTCACCCAATTATTGCATACATACTGTAGCTTG TATTTGAATGAAGATGATCTCACCATAGGATACTCTACT CCATTCCAAATAGATTCAAGTTGTATGTGTCCTAATTAA AACTATTTCTGGTTTCACAGAAAAGTGTGTCACTTTAAT TTCGTTAGTTTCATCATAAAATATATTTTTTGTACTGTA CTATAGAGATTTGATGTTGTATATATTATCATTTTTCTC GTCTACAAACTGGGTCAAACGTAGACAAGGTTGACACAG GACAAACATAAGACTTCGATTAATTTGGAACCGAGGGAG TGGTATGTTTACCAGACAAATCCTATGTTCGTTTATTGA ATCATTAGAATTATGTACTAGCTATTAGTTGGATCAAGA TGATACATAAGGTTAAAAGGTATTAGTATAATCAGGTGA TCCTTAGGCTGGTCTTTTTTTTTTCTTCTGATGGCTTCT TTATGAAAGATTTGTATTGCAATGGTGTCGTGGACACTT GATAAGAAACTGAAACTGGTTTACTTTGCTGGCATCTCT AGTTGATCGTTAGCTGACTATTTTGCTCTTCAGGGAACA ACGGTGGTGGATAACCTGTTGAACAGTGAGGATGTCCAC TACATGCTCGAGGCCCTGGACGCGCTCGGGCTCTCCGTG GAAGCAGACAAAGTTGCAAAAAGAGCTCTAGTCGTCGGC TGTGGCGGCAGGTTCCCGATTGAGAAGGATGCCAAGGAG GAAGTAAAGCTCTTCTTGGGCAACGCTGGAACTGCGATG CGGCCATTGACGGCGGCTGTAGTAGCTGCTGGTGGAAAT GCAACGTATGTTTCTTTTCTTTAATCCTTATTATGGGAA TAAGTATGAGTTCCGTGGTTATGCTTTGAGACTGATGGT TTATGTCTCTCTTCTGAACTTCAGTTATGTTCTTGATGG AGTACCAAGAATGAGGGAGCGACCTATCGGTGACTTAGT TGTCGGTTTGAAACAACTAGGTGCGAATGTTGATTGTTT CCTCGGCACCGACTGCCCACCTGTTCGGATCAACGGCAT TGGAGGGCTACCTGGTGGCAAGGTTAGCCTCATCAACTT CCCTTTTATGCGCTTTTGTACACACATTTCAGTTCTCTG AAAAAAACAAGATTATGCGACCTTTAAAATAGCCATAAC CATTAGGCCCTATTTCGTGTAAAACAGATATGCTGATTG TGTTGTGGTCTTAGATCACACGGCCTATCATAAATTAGC 190 WO 2013/039990 PCT/US2012/054789 ACTTAACATTGAATTGCATTCCACAGGTTAAGCTATCTG GTTCCATCAGCAGCCAGTACTTGAGTTCCTTGCTGATGG CTGCTCCTTTGGCTCTTGGGGATGTTGAGATTGAAATCA TTGATAAACTAATCTCTGTTCCTTATGTTGAAATGACAT TGAGATTGATGGAGCGTTTTGGCGTGACGGCAGAGCATT CTGATAGCTGGGACAGATTCTACATTAAAGGAGGACAGA AGTACAAGTAAGTTTTGAATTGTTCTGCTTATTCTAAAC ATTTGTCCAAACATTTGACTTCTGGATAAACTAGGGAAT TGAACATTGGAAAGAACTATTGACTGCTCAACTTACTGT TATTAGCTAAGTCAAGCTTTACTAGGAAATGAGTAACTC TGCTACTTACAATGCACTGGCTGCACAGCTATGTTTTCT GGTGCATAAACTATTGTCTGCCCAAATAACTTTAATCAT CTGGTTAGGACCAAACTTGTAGTAGTTATGAACTGTACA AGGAAATCAGTGTGACAAATCTCCGCTACTTACAATGAC ATTGGACGGTTATATTTTCTTGTGCATAAACTTGGTCAC ATCAGAAGTGCCATCCATCTAAAAAAGGGTGAGAATTGA GAACATATGCAGCTTAATGACAGCTGTTTGGCAATAAGC ATTTCTTTTGCGGATGATTCTTGATTTGCTTCTTTTAGC CTTTTTTATTGTTACTAGTTGAATGTCCGTGCTTCGCCA CGGCTCCTTAGTGTATATTTAATGGCATTCGTGTTATAC GGATAAAGATACTATGTATGTAAATATTGAAAGTACTTT TTTTGGACCCCCTTCCGGCATGTTCTATTGTCTTCATCG TCGAAGCCAAATGTTACATTGGGATATCTGCTGCCAAAT GTTGCAGCAGGATATGCATCCTGATTTTACTGAGCATAC TTCACTGATGTAATTGAAACTGTCAGTTCAAACTTCATA AAAGTTGCAGTAATCGCTTCCTAAACAAGCCCTCCCTTG CTCTGGAATTGACAATTGACAGGTCCCCTGGAAATGCCT ATGTCGAAGGTGATGCCTCAAGTGCGAGCTATTTCTTGG CTGGCGCTGCAATCACTGGAGGAACTGTGACTGTCCAAG GTTGCGGCACCACCAGTTTGCAGGTACAACCAGTTTTAA CCATTTGGTTAAGCATACTTGCGGTATATAACATAATCA AAGATATACTGCTGTCAACCAAACTGATTTAAGTGGACA TTCATTTATGAATCTATATAACTACAGTACTGTAAGTCG GTTTCTTGTGCTATCTCCCTGACGATGATTAATATTGCA GGGTGATGTGAAATTTGCTGAGGTACTAGAAATGATGGG AGCGAAAGTTACATGGACCGACACTAGTGTAACTGTTAC TGGTCCACCACGTCAGCCCTTTGGAAGGAAACACCTAAA AGCTGTTGATGTCAACATGAACAAAATGCCTGATGTTGC CATGACTCTTGCCGTTGTTGCCCTTTTTGCCGATGGTCC AACTGCTATCAGAGATGGTAAACCCTCTTATGTGTTGCT GTTGATTTCTTTTGGATGGATTCCGCTACAGCACATGAT TTGTTCCTGACACTTGTCCATTCTCCTCTGTAGTTGCCT CTTGGAGAGTGAAGGAAACCGAGAGAATGGTGGCAATCC GGACGGAACTAACAAAGGTAGCACACCTATCTCCACTTC TTATATTTCAGCTCACTGTTGCACTCCCCAGTGCTTAGT CTCACCTGTTGTGTGCCTCTGTGCTATAGCTGGGAGCAA CGGTAGAGGAAGGCCCAGACTACTGCATTATCACACCAC CAGAGAAGCTGAACGTCACGGCAATCGACACCTACGATG ACCACCGGATGGCGATGGCCTTCTCCCTCGCCGCCTGCG CTGAGGTGCCTGTCACGATCAGGGACCCTGGGTGCACCC GCAAGACCTTCCCCAACTACTTTGACGTGCTAAGCACCT TCGTGAAGAACTAGCTCGATGAAAATCTACAGTGTATCG CATTTGTACTTTTGTAGCCTGTCCATGGTCCGAGGAAAT TTTTACTGTTTTGGTCTTCTTGCGAAATGATTTATGAGT 191 WO 2013/039990 PCT/US2012/054789 GTAATACTAGTTTTGTAGCATGGCGTGGGGCTTTTGAGG TAAAATGAGTTGTATGCATACTGAGTTCGTTTTGAATAA GAAGCAAGTTAGGAGTACCATAGACCATACTGTGACCTA CATGTTCTTCCGTTTCCAGAGGTATTATGTTGGCTGCTG GTACTCAAGTGTGTTCGAAAACTACTCGACAGCCATGGA ATTTGGGAGATGCCATTTGGGTATGTGGATGCTTGAGGA AGATCATCAAAGCAAACAAGAACACCAGTCGATGGTAAA ACAGTGCAGCTTGCACCAAGAATGTTTGCCTATCAGAGT AAACAAACCAGACT CAGCAGATAT GAAAAAAAC TCAGCA CTGTGACACTCGTGCTAAAACTAATTTCATTTAGGCCGT GGAGTAGGCCATTGCATACTTACGTATTAGAGCATCTCT AGTCGAGTCCTAGAGCATCTCTAGTCGAGTCCCCACAAA CGGCGCCGGATCGAGCGCTTGGGGGACGAGTTTTGTTCG TGCCGTGTTTGGGGTACATCGCTCCCTAGTCGCGTCCCC CAAACGCCGTCCCCAATGAGGAATTCAAAATAGTTTGTG CATTTAAAAAAGATGGTGTTCGTCGAAGTCGTCGCGATC AAAGTACTTGGCGCGCGATCATATTACAGGCCGACTTGC ACAAACATAGATCCTCCAGAACGGTCCACTTGGGACAGT GTGCCCTACGCCTTCTTCTTCTTTTCCTCCGGACCGGGT CCTGGCTCGTACGTCGGGGAGTAGAACATAGCGTTGGGG TTGAAGCCGTCACGAGGCAGCGCATCCTCGTACCGCGGC AACAAGTTTGGTGTCACGCACCCGGGAGTGGCGGAGGGG CCGTCGTTGTAGAACCCGGATGTCGA 192

权利要求:
Claims (35)
[1] 1. A method of plant control comprising: treating a plant with a composition comprising a polynucleotide and a transfer agent, wherein said polynucleotide is essentially identical or essentially complementary to a portion of an EPSPS gene sequence or fragment thereof, or to a portion of an RNA transcript of said EPSPS gene sequence or fragment thereof, wherein said EPSPS gene sequence is selected from the group consisting of SEQ ID NO: 1-120 or a polynucleotide fragment thereof, whereby said plant growth or development or reproductive ability is reduced or said plant is more sensitive to an EPSPS inhibitor herbicide relative to a plant not treated with said composition.
[2] 2. The method as claimed in claim 1, wherein said transfer agent is an organosilicone surfactant composition or compound contained therein.
[3] 3. The method as claimed in claim 1, wherein said polynucleotide fragment is 19 contiguous nucleotides, 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO: 1-120.
[4] 4. The method as claimed in claim 3, wherein said polynucleotide fragment is selected from the group consisting of sense or anti-sense ssDNA or ssRNA, dsRNA, or dsDNA, or dsDNA/RNA hybrids.
[5] 5. The method as claimed in claim 1, wherein said plant is selected from the group consisting of Amaranthus-palmeri, Amaranthusrudis, Amaranthus-graecizans, Amaranthus-hybridus, Amaranthuslividus, Amaranthus-spinosus, Amaranthus thunbergii, Amaranthusviridis, Lolium-multiflorum, Lolium-rigidium, Ambrosiaartemisiifolia, Ambrosiatrifida, Euphorbia-heterophylla, Kochiascoparia, Abutilontheophrasti, Sorghum-halepense, Chenopodium-album, Commelinadiffusa, Conyza-candensis, Digitaria-sanguinalis,.
[6] 6. The method as claimed in claim 1, wherein said composition further comprises said EPSPS inhibitor herbicide and external application to a plant with said composition.
[7] 7. The method as claimed in claim 6, wherein said composition further comprises one or more herbicides different from said EPSPS inhibitor herbicide. 193 WO 2013/039990 PCT/US2012/054789
[8] 8. The method as claimed in claim 7, wherein said composition further comprises an auxin-like herbicide.
[9] 9. The method as claimed in claim 8, wherein said auxin-like herbicide is dicamba or 2,4-D.
[10] 10. The method as claimed in claim 3, wherein said composition comprises any combination of two or more of said polynucleotide fragments and external application to a plant with said composition.
[11] 11. A composition comprising a polynucleotide and a transfer agent, wherein said polynucleotide is essentially identical or essentially complementary to an EPSPS gene sequence or fragment thereof, or to an RNA transcript of said EPSPS gene sequence, wherein said EPSPS gene sequence is selected from the group consisting of SEQ ID NO: 1-120 or a polynucleotide fragment thereof, and whereby a plant treated with said composition has its growth or development or reproductive ability regulated, suppressed or delayed or said plant is more sensitive to an EPSPS inhibitor herbicide as a result of said polynucleotide containing composition relative to a plant not treated with said composition.
[12] 12. The composition of claim 11, wherein said transfer agent is an organosilicone composition.
[13] 13. The composition of claim 11, wherein said polynucleotide fragment is 19 contiguous nucleotides, 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO: 1-120.
[14] 14. The composition of claim 11, wherein said polynucleotide is selected from the group consisting of SEQ ID NO: 121-3222.
[15] 15. The composition of claim 11, wherein said polynucleotide is selected from the group consisting of SEQ ID NO:3223-3542.
[16] 16. The composition of claim 11, further comprising an EPSPS inhibitor herbicide.
[17] 17. The composition of claim 16, wherein said EPSPS inhibitor molecule is glyphosate.
[18] 18. The composition of claim 17, further comprising a co-herbicide.
[19] 19. The composition of claim 18, wherein said co-herbicide is an auxin-like herbicide.
[20] 20. The method as claimed in claim 8, wherein said auxin-like herbicide is dicamba or 2,4-D.
[21] 21. A method of reducing expression of an EPSPS gene in a plant comprising: external application to a plant of a composition comprising a polynucleotide and a transfer agent, wherein said polynucleotide is essentially identical or essentially complementary to an EPSPS gene 194 WO 2013/039990 PCT/US2012/054789 sequence, or to the RNA transcript of said EPSPS gene sequence, wherein said EPSPS gene sequence is selected from the group consisting of SEQ ID NO: 1-120 or a polynucleotide fragment thereof, whereby said expression of said EPSPS gene is reduced relative to a plant in which the composition was not applied.
[22] 22. The method as claimed in claim 21, wherein said transfer agent is an organosilicone compound.
[23] 23. The method as claimed in claim 21, wherein said polynucleotide fragment is 19 contiguous nucleotides, 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO: 1-120.
[24] 24. The method as claimed in 21, wherein said polynucleotide molecule is selected from the group consisting of sense or anti-sense ssDNA or ssRNA, dsRNA, or dsDNA, or dsDNA/RNA hybrids.
[25] 25. A microbial expression cassette comprising a polynucleotide fragment of 19 contiguous nucleotides, 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO: 1-120.
[26] 26. A method of making a polynucleotide comprising a) transforming the microbial expression cassette of claim 25 into a microbe; b) growing said microbe; c) harvesting a polynucleotide from said microbe, wherein said polynucleotide is 19 contiguous nucleotides, 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO: 1-120.
[27] 27. A method of identifying polynucleotides useful in modulating EPSPS gene expression when externally treating a plant comprising: a) providing a plurality of polynucleotides that comprise a region essentially identical or essentially complementary to a polynucleotide fragment of 19 contiguous nucleotides, 20 contiguous nucleotides or at least 21 contiguous nucleotides in length and at least 85 percent identical to an EPSPS gene sequence selected from the group consisting of SEQ ID NO: 1-120; b) externally treating said plant with one or more of said polynucleotides and a transfer agent; c) analyzing said plant or extract for modulation of EPSPS gene expression, and whereby a plant treated with said composition has its growth or development or reproductive ability regulated, suppressed or delayed or said plant is more sensitive to an EPSPS 195 WO 2013/039990 PCT/US2012/054789 inhibitor herbicide as a result of said polynucleotide containing composition relative to a plant not treated with said composition.
[28] 28. The method as claimed in 27, wherein said plant is selected from the group consisting of Amaranthus-palmeri, Amaranthusrudis, Amaranthus-graecizans, Amaranthus-hybridus, Amaranthuslividus, Amaranthus-spinosus, Amaranthus thunbergii, Amaranthusviridis, Lolium-multiflorum, Lolium-rigidium, Ambrosiaartemisiifolia, Ambrosiatrifida, Euphorbia-heterophylla, Kochiascoparia, Abutilontheophrasti, Sorghum-halepense, Chenopodium-album, Commelinadiffusa, Conyza-candensis, Digitaria-sanguinalis,.
[29] 29. The method as claimed in 27, wherein said EPSPS gene expression is reduced relative to a plant not treated with said polynucleotide fragment and a transfer agent.
[30] 30. The method as claimed in 27, wherein said transfer agent is an organosilicone compound.
[31] 31. An agricultural chemical composition comprising an admixture of a polynucleotide and a glyphosate herbicide and a co-herbicide, wherein said polynucleotide is essentially identical or essentially complementary to a portion of an EPSPS gene sequence or fragment thereof, or to a portion of an RNA transcript of said EPSPS gene sequence or fragment thereof, wherein said EPSPS gene sequence is selected from the group consisting of SEQ ID NO: 1-120 or a polynucleotide fragment thereof, and whereby a plant treated with said composition has its growth or development or reproductive ability regulated, suppressed or delayed or said plant is more sensitive to an EPSPS inhibitor herbicide as a result of said polynucleotide containing composition relative to a plant not treated with said composition.
[32] 32. The agricultural chemical composition of claim 31, wherein said co-herbicide is selected from the group consisting of amide herbicides, arsenical herbicides, benzothiazole herbicides, benzoylcyclohexanedione herbicides, benzofuranyl alkylsulfonate herbicides, carbamate herbicides, cyclohexene oxime herbicides, cyclopropylisoxazole herbicides, dicarboximide herbicides, dinitroaniline herbicides, dinitrophenol herbicides, diphenyl ether herbicides, dithiocarbamate herbicides, halogenated aliphatic herbicides, imidazolinone herbicides, inorganic herbicides, nitrile herbicides, organophosphorus herbicides, oxadiazolone herbicides, oxazole herbicides, phenoxy herbicides, phenylenediamine herbicides, pyrazole herbicides, pyridazine herbicides, pyridazinone herbicides, pyridine herbicides, pyrimidinediamine herbicides, pyrimidinyloxybenzylamine herbicides, quaternary ammonium herbicides, thiocarbamate herbicides, thiocarbonate herbicides, thiourea herbicides, triazine herbicides, 196 WO 2013/039990 PCT/US2012/054789 triazinone herbicides, triazole herbicides, triazolone herbicides, triazolopyrimidine herbicides, uracil herbicides, and urea herbicides.
[33] 33. An agricultural chemical composition comprising an admixture of a polynucleotide and a glyphosate herbicide and a pesticide, wherein said polynucleotide is essentially identical or essentially complementary to a portion of an EPSPS gene sequence, or to a portion of an RNA transcript of said EPSPS gene sequence, wherein said EPSPS gene sequence is selected from the group consisting of SEQ ID NO: 1-120 or a polynucleotide fragment thereof, and whereby a plant treated with said composition has its growth or development or reproductive ability regulated, suppressed or delayed or said plant is more sensitive to an EPSPS inhibitor herbicide as a result of said polynucleotide containing composition relative to a plant not treated with said composition.
[34] 34. The agricultural chemical composition of claim 33, wherein said pesticide is selected from the group consisting of insecticides, fungicides, nematocides, bactericides, acaricides, growth regulators, chemosterilants, semiochemicals, repellents, attractants, pheromones, feeding stimulants, and biopesticides.
[35] 35. A polynucleotide molecule applied to the surface of a plant that enhances said plant sensitivity to a glyphosate containing herbicide composition, wherein said polynucleotide comprises a homologous or complementary polynucleotide having at least 85 percent idendity to a polynucleotide selected from the group consisting of SEQ ID NO: 3781-3789. 197

类似技术:

---

公开号 | 公开日 | 专利标题

---

EP2756085B1|2019-03-20|Methods and compositions for weed control

---

AU2012308737B2|2018-06-14|Methods and compositions for weed control

---

EP2755987B1|2018-06-06|Methods and compositions for weed control

---

US9416363B2|2016-08-16|Methods and compositions for weed control

---

AU2014235180C1|2020-07-30|Methods and compositions for weed control

---

EP2756083B1|2020-08-19|Methods and compositions for weed control

---

CA2848685A1|2013-03-21|Methods and compositions for weed control comprising topical application of a glutamine synthetase polynucleotide

---

CA2848680A1|2013-03-21|Methods and compositions for weed control

---

AU2012308694A1|2014-03-27|Methods and compositions for weed control

---

US20190264222A1|2019-08-29|Methods and Compositions for Weed Control Using EPSPS Polynucleotides

---

US10760086B2|2020-09-01|Methods and compositions for weed control

同族专利:

---

公开号 | 公开日

---

EP2756085A1|2014-07-23|

---

CA2848669A1|2013-03-21|

---

UA115534C2|2017-11-27|

---

WO2013039990A9|2013-05-16|

---

US20130288895A1|2013-10-31|

---

UY34325A|2013-04-30|

---

EP2756085B1|2019-03-20|

---

CN103975068A|2014-08-06|

---

AU2012308818B2|2018-06-21|

---

BR112014005951A2|2017-04-04|

---

EP2756085A4|2015-03-04|

---

AR088754A1|2014-07-02|

---

MX2014003066A|2014-07-17|

---

MX350775B|2017-09-15|

---

WO2013039990A1|2013-03-21|

引用文献:

---

公开号 | 申请日 | 公开日 | 申请人 | 专利标题

---

US36449A||1862-09-16||Improvement in the |

---

US37287A||1863-01-06||Improvement in boot and shoe soles |

---

US4535060A|1983-01-05|1985-08-13|Calgene, Inc.|Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use|

---

US5331107A|1984-03-06|1994-07-19|Mgi Pharma, Inc.|Herbicide resistance in plants|

---

US4761373A|1984-03-06|1988-08-02|Molecular Genetics, Inc.|Herbicide resistance in plants|

---

US5304732A|1984-03-06|1994-04-19|Mgi Pharma, Inc.|Herbicide resistance in plants|

---

EP0189707B1|1984-12-28|1993-08-25|Plant Genetic Systems N.V.|Recombinant dna which can be introduced into plant cells|

---

JP2615013B2|1985-08-07|1997-05-28|モンサントコンパニ−|Glyphosate resistant chimeric gene|

---

US4940835A|1985-10-29|1990-07-10|Monsanto Company|Glyphosate-resistant plants|

---

US4810648A|1986-01-08|1989-03-07|Rhone Poulenc Agrochimie|Haloarylnitrile degrading gene, its use, and cells containing the gene|

---

ES2018274T5|1986-03-11|1996-12-16|Plant Genetic Systems Nv|VEGETABLE CELLS RESISTANT TO GLUTAMINE SYNTHETASE INHIBITORS, PREPARED BY GENETIC ENGINEERING.|

---

US5273894A|1986-08-23|1993-12-28|Hoechst Aktiengesellschaft|Phosphinothricin-resistance gene, and its use|

---

US5605011A|1986-08-26|1997-02-25|E. I. Du Pont De Nemours And Company|Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase|

---

US5378824A|1986-08-26|1995-01-03|E. I. Du Pont De Nemours And Company|Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase|

---

US5013659A|1987-07-27|1991-05-07|E. I. Du Pont De Nemours And Company|Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase|

---

US5312910A|1987-05-26|1994-05-17|Monsanto Company|Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthase|

---

US5145783A|1987-05-26|1992-09-08|Monsanto Company|Glyphosate-tolerant 5-endolpyruvyl-3-phosphoshikimate synthase|

---

US4971908A|1987-05-26|1990-11-20|Monsanto Company|Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthase|

---

US5310667A|1989-07-17|1994-05-10|Monsanto Company|Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases|

---

US5550318A|1990-04-17|1996-08-27|Dekalb Genetics Corporation|Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof|

---

CA2083948C|1990-06-25|2001-05-15|Ganesh M. Kishore|Glyphosate tolerant plants|

---

US5633435A|1990-08-31|1997-05-27|Monsanto Company|Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases|

---

US5866775A|1990-09-28|1999-02-02|Monsanto Company|Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases|

---

FR2673643B1|1991-03-05|1993-05-21|Rhone Poulenc Agrochimie|TRANSIT PEPTIDE FOR THE INSERTION OF A FOREIGN GENE INTO A PLANT GENE AND PLANTS TRANSFORMED USING THIS PEPTIDE.|

---

FR2673642B1|1991-03-05|1994-08-12|Rhone Poulenc Agrochimie|CHIMERIC GENE COMPRISING A PROMOTER CAPABLE OF GIVING INCREASED TOLERANCE TO GLYPHOSATE.|

---

US5731180A|1991-07-31|1998-03-24|American Cyanamid Company|Imidazolinone resistant AHAS mutants|

---

US5767373A|1994-06-16|1998-06-16|Novartis Finance Corporation|Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms|

---

AT342968T|1995-04-20|2006-11-15|Basf Ag|BASED ON YOUR STRUCTURE DESIGNED HERBICIDE RESISTANT PRODUCTS|

---

US5853973A|1995-04-20|1998-12-29|American Cyanamid Company|Structure based designed herbicide resistant products|

---

FR2734842B1|1995-06-02|1998-02-27|Rhone Poulenc Agrochimie|DNA SEQUENCE OF A HYDROXY-PHENYL PYRUVATE DIOXYGENASE GENE AND OBTAINING PLANTS CONTAINING A HYDROXY-PHENYL PYRUVATE DIOXYGENASE GENE, TOLERANT TO CERTAIN HERBICIDES|

---

FR2751347B1|1996-07-16|2001-12-07|Rhone Poulenc Agrochimie|CHIMERIC GENE WITH MULTIPLE HERBICIDE TOLERANCE GENES, PLANT CELL AND PLANT TOLERANT WITH MULTIPLE HERBICIDES|

---

DE19652284A1|1996-12-16|1998-06-18|Hoechst Schering Agrevo Gmbh|Novel genes encoding amino acid deacetylases with specificity for N-acetyl-L-phosphinothricin, their isolation and use|

---

US7022896B1|1997-04-04|2006-04-04|Board Of Regents Of University Of Nebraska|Methods and materials for making and using transgenic dicamba-degrading organisms|

---

US6245968B1|1997-11-07|2001-06-12|Aventis Cropscience S.A.|Mutated hydroxyphenylpyruvate dioxygenase, DNA sequence and isolation of plants which contain such a gene and which are tolerant to herbicides|

---

US6069115A|1997-11-12|2000-05-30|Rhone-Poulenc Agrochimie|Method of controlling weeds in transgenic crops|

---

US6506559B1|1997-12-23|2003-01-14|Carnegie Institute Of Washington|Genetic inhibition by double-stranded RNA|

---

CA2381927A1|1999-08-13|2001-02-22|Syngenta Participations Ag|Herbicide-tolerant protoporphyrinogen oxidase|

---

FR2815969B1|2000-10-30|2004-12-10|Aventis Cropscience Sa|TOLERANT PLANTS WITH HERBICIDES BY METABOLIC BYPASS|

---

CN101684458A|2000-10-30|2010-03-31|弗迪亚股份有限公司|Novel glyphosate N-acetyltransferase genes|

---

CN1162542C|2000-11-03|2004-08-18|中国科学院微生物研究所|Vegetable lectin gene|

---

US7312379B2|2000-12-07|2007-12-25|Syngenta Limited|Methods for production of plants resistant to HPPD herbicides|

---

US20050246784A1|2001-02-16|2005-11-03|Gunnar Plesch|Method for identifying herbicidally active substances|

---

US6743905B2|2001-04-16|2004-06-01|Applera Corporation|Mobility-modified nucleobase polymers and methods of using same|

---

WO2003077648A2|2001-11-08|2003-09-25|Paradigm Genetics, Inc.|Methods for the identification of herbicides and the modulation of plant growth|

---

DE10161765A1|2001-12-15|2003-07-03|Bayer Cropscience Gmbh|Substituted phenyl derivatives|

---

WO2003076409A1|2002-03-14|2003-09-18|Syngenta Participations Ag|Derivatives of 1-phenyl-3-phenylpyrazole as herbicides|

---

AR039208A1|2002-04-03|2005-02-09|Syngenta Participations Ag|PHENYL AND PIRIDYL ALKIN COMPOUNDS, HERBICIDE COMPOSITION CONTAINING THEM, PROCEDURE FOR PREPARATION OF THOSE AND PROCEDURE TO COMBAT THE GROWTH OF INDENATED PLANTS|

---

KR20040102153A|2002-04-25|2004-12-03|바스프 악티엔게젤샤프트|3-heteroaryl substituted 5-methyloxymethyl isoxazolines used as herbicides|

---

CA2484035A1|2002-04-26|2003-11-06|Ishihara Sangyo Kaisha, Ltd.|Pyridine compounds or salts thereof and herbicides containing the same|

---

DE10219435A1|2002-05-02|2003-11-13|Bayer Cropscience Ag|Substituted pyrazolo-pyrimidin-4-ones|

---

AR040413A1|2002-05-31|2005-04-06|Syngenta Participations Ag|HETEROCICLILALQUINOS ACTIVE AS HERBICIDES|

---

AR041181A1|2002-07-01|2005-05-04|Syngenta Participations Ag|HERBICIDE TENYLALKINS AND PROCEDURE FOR PREPARING SUCH COMPOUNDS|

---

AR041182A1|2002-07-01|2005-05-04|Syngenta Participations Ag|DERIVATIVES OF PHENOXIPROPENYLPHENYL AND ITS USE AS HERBICIDES|

---

CA2493030C|2002-07-24|2011-04-19|Basf Aktiengesellschaft|Synergistically acting herbicidal mixtures|

---

AU2003252259A1|2002-07-26|2004-02-16|Nihon Nohyaku Co., Ltd.|Novel haloalkylsulfonanilide derivatives, herbicides and usage thereof|

---

AR044743A1|2002-09-26|2005-10-05|Nihon Nohyaku Co Ltd|HERBICIDE, METHOD OF USE, DERIVED FROM REPLACED TIENOPIRIMIDINE, INTERMEDIATE COMPOUNDS, AND PROCEDURES USED TO PRODUCE THEM,|

---

WO2004035564A1|2002-10-17|2004-04-29|Syngenta Participations Ag|Pyridine derivatives useful as herbicides|

---

AU2003274022A1|2002-10-17|2004-05-04|Syngenta Participations Ag|3-heterocyclylpyridine derivatives useful as herbicides|

---

EP1556346A1|2002-10-18|2005-07-27|Basf Aktiengesellschaft|1-phenylpyrrolidine-2-one-3-carboxamides|

---

WO2004035545A2|2002-10-18|2004-04-29|E.I. Du Pont De Nemours And Company|Azolecarboxamide herbicides|

---

CN1521165A|2003-01-30|2004-08-18|拜尔农作物科学股份公司|Thiophene derivative|

---

DE10303883A1|2003-01-31|2004-08-12|Bayer Cropscience Ag|Substituted pyrimidines|

---

CN1526704A|2003-03-06|2004-09-08|拜尔农作物科学股份公司|Substituted triazolformamide compound|

---

JP2005015390A|2003-06-26|2005-01-20|Bayer Cropscience Ag|Azolidine derivative and herbicide|

---

CN1208325C|2003-07-04|2005-06-29|中国科学院上海有机化学研究所|2-pyrimidine oxy-N-ureido phenyl-benzyl amide compound, preparing method and use thereof|

---

WO2005007627A1|2003-07-18|2005-01-27|Nihon Nohyaku Co., Ltd.|Phenylpyridine derivative, intermediate therefor, and herbicide containing the same as active ingredient|

---

WO2005040152A1|2003-10-20|2005-05-06|E.I. Dupont De Nemours And Company|Heteroyclylphenyl-and heterocyclylpyridyl-substituted azolecarboxamides as herbicides|

---

WO2005047233A1|2003-10-31|2005-05-26|Syngenta Participations Ag|Novel herbicides|

---

WO2005047281A1|2003-11-13|2005-05-26|Syngenta Participations Ag|Novel herbicides|

---

EA011928B1|2003-12-19|2009-06-30|Басф Акциенгезельшафт|Heteroaroyl-substituted phenylalanine amides|

---

WO2005061443A2|2003-12-19|2005-07-07|Basf Aktiengesellschaft|Benzoyl-substituted phenylalanine amides|

---

GT200500013A|2004-01-23|2005-08-10||HERBICIDE AMIDAS|

---

DE102004011705A1|2004-03-10|2005-09-29|Bayer Cropscience Gmbh|Substituted 4- -pyrimidines|

---

WO2005095335A1|2004-03-31|2005-10-13|Kureha Corporation|Ylide compounds, process for production of the same, and use thereof as herbicide and intermediates of drugs|

---

CN1984558B|2004-04-30|2011-01-12|美国陶氏益农公司|Novel herbicide resistance genes|

---

WO2006006569A1|2004-07-12|2006-01-19|Nihon Nohyaku Co., Ltd.|Phenylpyridine derivative or salt thereof, herbicide containing the same as active ingredient, and method of use thereof|

---

US20060135758A1|2004-08-31|2006-06-22|Kunsheng Wu|Soybean polymorphisms and methods of genotyping|

---

AT459605T|2004-09-03|2010-03-15|Syngenta Ltd|ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES|

---

EP1791825B1|2004-09-16|2008-09-17|Basf Se|Benzoyl-substituted serine amides|

---

KR20070058618A|2004-09-16|2007-06-08|바스프 악티엔게젤샤프트|Heteroaroyl-substituted serine amides utilized as herbicides|

---

DE602005018084D1|2004-10-05|2010-01-14|Syngenta Ltd|ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES|

---

DE102004054665A1|2004-11-12|2006-05-18|Bayer Cropscience Gmbh|Substituted bicyclic and tricyclic pyrazole derivatives Methods for the preparation and use as herbicides and plant growth regulators|

---

EP1852425A1|2005-02-24|2007-11-07|Nihon Nohyaku Co., Ltd.|Novel haloalkylsulfonanilide derivative, herbicide, and method of use thereof|

---

GB0510151D0|2005-05-18|2005-06-22|Syngenta Ltd|Novel herbicides|

---

US7786046B2|2005-05-25|2010-08-31|Basf Aktiengesellschaft|Benzoyl-substituted serineamides|

---

MX2007014490A|2005-05-25|2008-02-11|Basf Ag|Heteroaroyl-substituted serine amides.|

---

DE102005031412A1|2005-07-06|2007-01-11|Bayer Cropscience Gmbh|3- [1-Halo-1-aryl-methane-sulfonyl] and 3- [1-halo-1-heteroaryl-methanesulfonyl] -isoxazoline derivatives, processes for their preparation and use as herbicides and plant growth regulators|

---

WO2007026834A1|2005-09-01|2007-03-08|Kumiai Chemical Industry Co., Ltd.|Pyrazole derivatives and herbicides for agricultural and horticultural use|

---

GB0526044D0|2005-12-21|2006-02-01|Syngenta Ltd|Novel herbicides|

---

AR058408A1|2006-01-02|2008-01-30|Basf Ag|PIPERAZINE COMPOUNDS WITH HERBICITY ACTION|

---

ES2342624T3|2006-01-05|2010-07-09|Basf Se|PIPERAZINE COMPOUNDS WITH HERBICIDE EFFECT.|

---

GB0603891D0|2006-02-27|2006-04-05|Syngenta Ltd|Novel herbicides|

---

TWI375669B|2006-03-17|2012-11-01|Sumitomo Chemical Co|Pyridazinone compound and use thereof|

---

BRPI0710930A2|2006-05-19|2012-02-14|Basf Se|compound process for preparing a compound, composition, processes for preparing compositions and for combating unwanted vegetation, and use of the compound|

---

US7884262B2|2006-06-06|2011-02-08|Monsanto Technology Llc|Modified DMO enzyme and methods of its use|

---

GB0614471D0|2006-07-20|2006-08-30|Syngenta Ltd|Herbicidal Compounds|

---

GB0617575D0|2006-09-06|2006-10-18|Syngenta Ltd|Herbicidal compounds and compositions|

---

US7897846B2|2006-10-30|2011-03-01|Pioneer Hi-Bred Int'l, Inc.|Maize event DP-098140-6 and compositions and methods for the identification and/or detection thereof|

---

TW200829171A|2006-11-17|2008-07-16|Nihon Nohyaku Co Ltd|Haloalkyl sulfonanilide derivatives or salts thereof, herbicide using it as effective constituent and use-method thereof|

---

GB0624760D0|2006-12-12|2007-01-17|Syngenta Ltd|Herbicidal compounds|

---

GB0625598D0|2006-12-21|2007-01-31|Syngenta Ltd|Novel herbicides|

---

WO2008084073A1|2007-01-11|2008-07-17|Basf Se|Heteroaryl-substituted serine amides|

---

CL2008000376A1|2007-02-09|2008-08-18|Du Pont|COMPOUNDS DERIVED FROM PIRIDINE N-OXIDES; HERBICIDE COMPOSITION; AND METHOD TO CONTROL THE GROWTH OF INDESEATED VEGETATION.|

---

JPWO2008102908A1|2007-02-23|2010-05-27|日産化学工業株式会社|Haloalkylsulfonanilide derivatives|

---

AU2008258254B2|2007-06-07|2014-07-03|Agriculture And Agri-Food Canada|Nanocarrier based plant transfection and transduction|

---

BRPI0812955A2|2007-06-12|2014-12-09|Basf Se|PIPERAZINE COMPOUNDS, USE OF A PIPERAZINE COMPOUND, COMPOSITION, AND METHOD FOR COMBATING UNWANTED VEGETATION|

---

CN101679316A|2007-06-12|2010-03-24|巴斯夫欧洲公司|Piperazine compounds with a herbicidal action|

---

TW200906807A|2007-06-22|2009-02-16|Basf Se|Piperazine compounds having herbicidal action|

---

KR100884933B1|2007-07-03|2009-02-23|주식회사경농|Optically active r-aryloxypropionic acid amides and herbicidal compositions comprising same|

---

CL2008002703A1|2007-09-14|2009-11-20|Sumitomo Chemical Co|Compounds derived from 1,4-dihydro-2h-pyridazin-3-one; herbicidal composition comprising said compounds; weed control method; use of said compounds for weed control; and intermediate compounds.|

---

US20110015084A1|2007-10-25|2011-01-20|Monsanto Technology Llc|Methods for Identifying Genetic Linkage|

---

US20110171287A1|2007-11-05|2011-07-14|Baltic Technology Develpment, Ltd.|Use of Oligonucleotides with Modified Bases as Antiviral Agents|

---

US20110152346A1|2007-11-05|2011-06-23|Baltic Technology Development Ltd.|Use of Oligonucleotides with Modified Bases in Hybridization of Nucleic Acids|

---

GB0722472D0|2007-11-15|2007-12-27|Syngenta Ltd|Herbicidal compounds|

---

EP2065373A1|2007-11-30|2009-06-03|Bayer CropScience AG|Chiral 3--5,5-dimethyl-4,5-dihydroisoxazole and 5,5-dimethyl-3-[ sulfinyl]-4,5-dihydroisoxazole derivatives, methods for their preparation and their use as herbicides and plant growth regulators|

---

EP2065374A1|2007-11-30|2009-06-03|Bayer CropScience AG|2-sulfinyl-thiazol-derivatives as herbicides and plant growth regulators|

---

CL2008003785A1|2007-12-21|2009-10-09|Du Pont|Pyridazine derived compounds; herbicidal compositions comprising said compounds; and method of controlling the growth of unwanted vegetation.|

---

GB0800856D0|2008-01-17|2008-02-27|Syngenta Ltd|Herbicidal compounds|

---

GB0800855D0|2008-01-17|2008-02-27|Syngenta Ltd|Herbicidal compounds|

---

CA2714460C|2008-03-03|2016-05-17|Ms Technologies Llc|Antibodies immunoreactive with mutant 5-enolpyruvylshikimate-3-phosphate synthase|

---

WO2009116151A1|2008-03-19|2009-09-24|アグロカネショウ株式会社|1-phenyl-5-difluoromethylpyrazole-4-carboxamide derivatives and herbicides containing the derivatives as the active ingredient|

---

GB0805318D0|2008-03-20|2008-04-30|Syngenta Ltd|Herbicidal compounds|

---

EP2135865A1|2008-06-17|2009-12-23|Bayer CropScience AG|Substituted 1-pyrazol-4-yl acetic acids, method for their production and their use as herbicides and plant growth regulators|

---

WO2009158258A1|2008-06-25|2009-12-30|E. I. Du Pont De Nemours And Company|Herbicidal dihydro oxo six-membered azinyl isoxazolines|

---

TWI455944B|2008-07-01|2014-10-11|Daiichi Sankyo Co Ltd|Double-stranded polynucleotides|

---

ES2566008T3|2008-07-10|2016-04-08|Regenesance B.V.|Complement antagonists and uses thereof|

---

EP2315760B1|2008-07-29|2013-03-06|Basf Se|Piperazine compounds with herbicidal effect|

---

KR101667063B1|2008-09-02|2016-10-17|닛산 가가쿠 고교 가부시키 가이샤|Ortho-substituted haloalkylsulfonanilide derivative and herbicide|

---

WO2010034153A1|2008-09-25|2010-04-01|沈阳化工研究院|New 2-pyrimidinyloxy benzoxy olefin acid ester compounds and uses thereof|

---

AU2009309837A1|2008-10-29|2010-05-06|Basf Se|Substituted pyridines having a herbicidal effect|

---

US20110207609A1|2008-10-31|2011-08-25|Basf Se|Piperazine Compounds With Herbicidal Effect|

---

CN102202504A|2008-10-31|2011-09-28|巴斯夫欧洲公司|Method for improving plant health|

---

US20110209253A1|2008-10-31|2011-08-25|Basf Se|Method for Improving Plant Health|

---

EP2194052A1|2008-12-06|2010-06-09|Bayer CropScience AG|Substituted 1.- and 1-pyrazol-4-yl acetic acids, method for their production and their use as herbicides and plant growth regulators|

---

DE102008063561A1|2008-12-18|2010-08-19|Bayer Cropscience Ag|Hydrazides, process for their preparation and their use as herbicides and insecticides|

---

WO2010069802A1|2008-12-18|2010-06-24|Basf Se|Heterocyclic diketone derivatives with herbicidal action|

---

EP2204366A1|2008-12-19|2010-07-07|Bayer CropScience AG|Herbicidal and insecticidal phenyl-substituted pyridazinones|

---

JP2010235603A|2009-03-13|2010-10-21|Sumitomo Chemical Co Ltd|Pyridazinone compound and use thereof|

---

EP2229813A1|2009-03-21|2010-09-22|Bayer CropScience AG|Pyrimidine-4-ylpropandinitrile derivatives, method for their manufacture and their use as herbicides and plant growth regulators|

---

GB0905441D0|2009-03-30|2009-05-13|Syngenta Ltd|Herbicidal compounds|

---

BRPI1016044B1|2009-04-06|2021-03-09|Syngenta Limited|herbicidal compounds, agronomically acceptable salt of the compound, herbicidal composition, method of selectively controlling pests at a site comprising crop plants and pests, method of producing said compound and use of the same|

---

EP2420493A4|2009-04-14|2012-09-05|Nissan Chemical Ind Ltd|Haloalkylsulfonanilide derivative|

---

GB0908293D0|2009-05-14|2009-06-24|Syngenta Ltd|Herbicidal compounds|

---

WO2011003776A2|2009-07-09|2011-01-13|Basf Se|Substituted cyanobutyrates having a herbicidal effect|

---

WO2011035874A1|2009-09-25|2011-03-31|Bayer Cropscience Ag|N- benzamides and the use thereof as herbicides|

---

CN103260393B|2009-11-23|2015-05-13|孟山都技术公司|Transgenic maize event mon 87427 and the relative development scale|

---

JP2011195561A|2009-11-24|2011-10-06|Sumitomo Chemical Co Ltd|Ketone compound, and herbicide comprising the same|

---

US9121022B2|2010-03-08|2015-09-01|Monsanto Technology Llc|Method for controlling herbicide-resistant plants|

---

CN101914540A|2010-08-09|2010-12-15|大连大学|Method for introducing RNA interference into plants|

---

CN102154364A|2010-12-31|2011-08-17|广西作物遗传改良生物技术重点开放实验室|Method for agrobacterium tumefaciens-mediated genetic transformation of sugarcane|US8097712B2|2007-11-07|2012-01-17|Beelogics Inc.|Compositions for conferring tolerance to viral disease in social insects, and the use thereof|

---

US8962584B2|2009-10-14|2015-02-24|Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd.|Compositions for controlling Varroa mites in bees|

---

US9121022B2|2010-03-08|2015-09-01|Monsanto Technology Llc|Method for controlling herbicide-resistant plants|

---

EP3382027A3|2011-09-13|2018-10-31|Monsanto Technology LLC|Methods and compositions for weed control|

---

BR112014005979A2|2011-09-13|2017-06-13|Monsanto Technology Llc|Weed control methods and compositions|

---

US9840715B1|2011-09-13|2017-12-12|Monsanto Technology Llc|Methods and compositions for delaying senescence and improving disease tolerance and yield in plants|

---

US10760086B2|2011-09-13|2020-09-01|Monsanto Technology Llc|Methods and compositions for weed control|

---

US10806146B2|2011-09-13|2020-10-20|Monsanto Technology Llc|Methods and compositions for weed control|

---

WO2013040057A1|2011-09-13|2013-03-21|Monsanto Technology Llc|Methods and compositions for weed control|

---

EP3296402B1|2011-09-13|2020-04-15|Monsanto Technology LLC|Methods and compositions for weed control|

---

US10829828B2|2011-09-13|2020-11-10|Monsanto Technology Llc|Methods and compositions for weed control|

---

US9920326B1|2011-09-14|2018-03-20|Monsanto Technology Llc|Methods and compositions for increasing invertase activity in plants|

---

US10240162B2|2012-05-24|2019-03-26|A.B. Seeds Ltd.|Compositions and methods for silencing gene expression|

---

WO2014062989A2|2012-10-18|2014-04-24|Monsanto Technology Llc|Methods and compositions for plant pest control|

---

US10683505B2|2013-01-01|2020-06-16|Monsanto Technology Llc|Methods of introducing dsRNA to plant seeds for modulating gene expression|

---

WO2014106837A2|2013-01-01|2014-07-10|A. B. Seeds Ltd.|ISOLATED dsRNA MOLECULES AND METHODS OF USING SAME FOR SILENCING TARGET MOLECULES OF INTEREST|

---

US10000767B2|2013-01-28|2018-06-19|Monsanto Technology Llc|Methods and compositions for plant pest control|

---

WO2014164797A2|2013-03-13|2014-10-09|Monsanto Technology Llc|Methods and compositions for weed control|

---

UA123082C2|2013-03-13|2021-02-17|Монсанто Текнолоджи Ллс|Methods and compositions for weed control|

---

US20140283211A1|2013-03-14|2014-09-18|Monsanto Technology Llc|Methods and Compositions for Plant Pest Control|

---

US10568328B2|2013-03-15|2020-02-25|Monsanto Technology Llc|Methods and compositions for weed control|

---

US9850496B2|2013-07-19|2017-12-26|Monsanto Technology Llc|Compositions and methods for controlling Leptinotarsa|

---

PL3030663T3|2013-07-19|2020-04-30|Monsanto Technology Llc|Compositions and methods for controlling leptinotarsa|

---

CN105849266A|2013-11-04|2016-08-10|孟山都技术公司|Compositions and methods for controlling arthropod parasite and pest infestations|

---

EP3080147B1|2013-12-10|2019-03-13|Beeologics, Inc.|Compositions and methods for virus control in varroa mite and bees|

---

AU2015206585A1|2014-01-15|2016-07-21|Monsanto Technology Llc|Methods and compositions for weed control using EPSPS polynucleotides|

---

BR112016022711A2|2014-04-01|2017-10-31|Monsanto Technology Llc|compositions and methods for insect pest control|

---

CN106795515B|2014-06-23|2021-06-08|孟山都技术公司|Compositions and methods for modulating gene expression via RNA interference|

---

RU2021123470A|2014-07-29|2021-09-06|Монсанто Текнолоджи Ллс|COMPOSITIONS AND METHODS FOR COMBATING PESTS|

---

CA2974101A1|2015-01-22|2016-07-28|Monsanto Technology Llc|Compositions and methods for controlling leptinotarsa|

---

AU2016270870A1|2015-06-02|2018-01-04|Monsanto Technology Llc|Compositions and methods for delivery of a polynucleotide into a plant|

---

WO2016196782A1|2015-06-03|2016-12-08|Monsanto Technology Llc|Methods and compositions for introducing nucleic acids into plants|

---

JP6242844B2|2015-10-01|2017-12-06|花王株式会社|Amino acid pesticide efficacy enhancer composition|

---

CN110346502A|2019-07-04|2019-10-18|广东省测试分析研究所（中国广州分析测试中心）|The method of 2,4-D and bentazone in water with ion chromatography|

法律状态:
2018-10-18| FGA| Letters patent sealed or granted (standard patent)|

优先权:

---

申请号 | 申请日 | 专利标题

---

US201161534057P| true| 2011-09-13|2011-09-13||

---

US61/534,057||2011-09-13||

---

PCT/US2012/054789|WO2013039990A1|2011-09-13|2012-09-12|Methods and compositions for weed control|

---